Cadaveric Hepatocytes Repopulate Diseased Livers: Life After Death
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Hepatocyte isolation is technically demanding, requires cadaveric liver donation, and hepatocytes cannot be expanded effectively in vitro.
“Hepatocytes have a high replicative potential in vivo3, 4, however hepatocyte isolation is technically demanding, requires cadaveric liver donation, and hepatocytes cannot be expanded effectively in vitro5.”
From Hepatic progenitor cells of biliary origin with liver repopulation capacity (2015) · cites this paper as [5]
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Hepatic progenitor cells of biliary origin with liver repopulation capacity
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- Authors
- Hay, D. C.
- Affiliations
- MRC Centre for Regenerative Medicine (GB)
- Corresponding author
- Hay, David C.
- ORCID
- Hay, David C.
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2010-09
- Volume
- 139
- Issue
- 3
- Pages
- 729-731
- ISSN
- 0016-5085 (ISSN-L)
- OpenAlex
- W2092753020
- Cited by
- 9
- References
- 16
- Citations by year
- 2023: 1 · 2015: 2 · 2013: 1 · 2012: 2
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Surgery › Organ Transplantation Techniques and Outcomes
- Health Sciences › Medicine › Hepatology › Liver physiology and pathology
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Keywords
- hepatocyte repopulation, liver failure, cell transplantation, liver regeneration, organ shortage, bridge to transplant, inherited metabolic liver disease, liver insufficiency
- MeSH terms
- Animals, Cadaver, Cell Separation, Cell Survival, Cells, Cultured, Humans, Hydrolases, Liver, Liver Regeneration, Temperature, Time Factors, Tyrosine, Biomarkers, Tyrosinemias, Hepatocytes, Cell Proliferation
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