Pathogenesis of cholestatic liver disease and therapeutic approaches
Hirschfield, Gideon M., Heathcote, E. Jenny, Gershwin, M. Eric·2010·Gastroenterology
Cited by (286)
Items 101–200 of 286
- Cell-specific regulatory effects of CXCR2 on cholestatic liver injuryTakanori Konishi, Rebecca M. Schuster, Holly S. Goetzman, Charles C. Caldwell, Alex B. Lentsch · 2019 · American Journal of Physiology-Gastrointestinal and Liver Physiology
- Fetal androgen exposure is a determinant of adult male metabolic healthKatarzyna J. Siemienowicz, Panagiotis Filis, Sophie Shaw, Alex Douglas, Jennifer L. Thomas, Sally Mulroy, Forbes A. Howie, Paul Fowler, William Colin Duncan, Mick T. Rae · 2019 · Scientific Reports
- A UPLC-MS/MS-based metabolomics analysis of the pharmacological mechanisms of rabdosia serra against cholestasisKaihui Zhang, Yufeng Yao, Meiqi Wang, Fangle Liu, Qian Wang, Huanhuan Ma, Yuanyuan Xie, Yunxia Ma, Pengyu Dai, Chenchen Zhu et al. · 2021 · Phytomedicine
- The Pyruvate Dehydrogenase Complex and Related Assemblies in Health and DiseaseOlwyn Byron, John Gordon LINDSAY · 2017 · Sub-cellular biochemistry/Subcellular biochemistry
- Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing CholangitisMatteo Tardelli, Francesca Virginia Bruschi, Claudia Daniela Fuchs, Thierry Claudel, Nicole Auer, Victoria Kunczer, Maximilian Baumgartner, Onne A. H. O. Ronda, Henkjan J. Verkade, Tatjana Stojaković et al. · 2019 · Hepatology
- Serum cell death biomarkers for prediction of liver fibrosis and poor prognosis in primary biliary cirrhosisSekiguchi, Tomohiro, Umemura, Takeji, Fujimori, Naoyuki, Shibata, Soichiro, Ichikawa, Yuki, Kimura, Takefumi, Joshita, Satoru, Komatsu, Michiharu, Matsumoto, Akihiro, Tanaka, Eiji et al. · 2015 · PLOS ONE
- Recent advances in three-dimensional cell culturing to assess liver function and dysfunction: from a drug biotransformation and toxicity perspectiveCarlemi Calitz, Josias Hendrik Hamman, Stephen J. Fey, Krzysztof Wrzesinski, Chrisna Gouws · 2018 · Toxicology Mechanisms and Methods
- Tutorial Review for Understanding of CholangiopathyYasuni Nakanuma · 2011 · International Journal of Hepatology
- Structure, Function, and Responses to InjuryJames M. Crawford, Paulette Bioulac‐Sage, Prodromos Hytiroglou · 2017 · Elsevier eBooks
- Pregnane X receptor and constitutive androstane receptor modulate differently CYP3A-mediated metabolism in early- and late-stage cholestasisDaniela Gabbia, Arianna Dalla Pozza, Laura Albertoni, Roberta Lazzari, Giorgia Zigiotto, Maria Carrara, Vincenzo Baldo, Tatjana Baldovin, Annarosa Floreani, Sara De Martin · 2017 · World Journal of Gastroenterology
- Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis: an Update on MR Imaging Findings with Recent DevelopmentsJelena Djokić Kovač, Marc‐André Weber · 2016 · Journal of Gastrointestinal and Liver Diseases
- Genetics in PBC: What Do the “Risk Genes” Teach Us?Gideon Morris Hirschfield, Katherine A. Siminovitch · 2014 · Clinical Reviews in Allergy & Immunology
- Metabolic Regulation of Macrophages by SIRT1 Determines Activation During Cholestatic Liver Disease in MiceAnna Isaacs‐Ten, Mar Moreno‐Gonzalez, Caitlin Bone, André Märtens, Federico Bernuzzi, Tobias Ludwig, Charlotte Hellmich, Karsten Hiller, Stuart A. Rushworth, Naiara Beraza · 2021 · Cellular and Molecular Gastroenterology and Hepatology
- TNF-α/IL-1β-licensed hADSCs alleviate cholestatic liver injury and fibrosis in mice via COX-2/PGE2 pathwayLuan, Xiaoyu, Chen, Peng, Li, Yaxin, Yuan, Xinying, Miao, Longyu, Zhang, Pengyu, Cao, Qilong, Song, Xiaomin, Di, Guohu · 2023 · Stem Cell Research & Therapy
- Characterization of Ursodeoxycholic and Norursodeoxycholic Acid as Substrates of the Hepatic Uptake Transporters OATP 1B1, OATP 1B3, OATP 2B1 and NTCPJörg König, Sabine Klatt, Karin Dilger, Martin F. Fromm · 2012 · Basic & Clinical Pharmacology & Toxicology
- Na+/H+ exchanger regulatory factor 1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injuryMan Li, Albert Mennone, Carol J. Soroka, Lee R. Hagey, Xinshou Ouyang, Edward J. Weinman, James Lorenzen Boyer · 2015 · Hepatology
- The Liver, Oxidative Stress, and AntioxidantsSael Casas‐Grajales, Pablo Muriel · 2017 · Elsevier eBooks
- Diagnostic Approach to the Patient with JaundiceJames M. Winger, Aaron J. Michelfelder · 2011 · Primary Care Clinics in Office Practice
- Targeted Metabolomics Reveals a Protective Role for Basal PPARα in Cholestasis Induced by α-NaphthylisothiocyanateManyun Dai, Huiying Hua, Hante Lin, Gang-Ming Xu, Xiaowei Hu, Fei Li, Frank J. Gonzalez, Aiming Liu, Julin Yang · 2018 · Journal of Proteome Research
- Biliary epithelium: A neuroendocrine compartment in cholestatic liver diseaseLaurent Ehrlich, Marinda Scrushy, Fanyin Meng, Terry C. Lairmore, Gianfranco D. Alpini, Shannon S. Glaser · 2018 · Clinics and Research in Hepatology and Gastroenterology
- Laboratory assessment of liver function and injury in childrenVicky L. Ng · 2014 · Cambridge University Press eBooks
- Sortilin 1 Loss-of-Function Protects Against Cholestatic Liver Injury by Attenuating Hepatic Bile Acid Accumulation in Bile Duct Ligated MiceJibiao Li, Benjamin Leeland Woolbright, Wen Ming Zhao, Yifeng Wang, David J. Matye, Bruno Hagenbuch, Hartmut Jaeschke, Tiangang Li · 2017 · Toxicological Sciences
- Current therapies and novel approaches for biliary diseasesIndu G. Rajapaksha, Peter Angus, Chandana B. Herath · 2019 · World Journal of Gastrointestinal Pathophysiology
- The Enterokine Fibroblast Growth Factor 15/19 in Bile Acid MetabolismMarica Cariello, Marilidia Piglionica, Raffaella Maria Gadaleta, Antonio Moschetta · 2019 · Handbook of experimental pharmacology
- Roles of Trained Immunity in the Pathogenesis of Cholangiopathies: A Therapeutic TargetYan, Chao, Koda, Stephane, Wu, Jing, Zhang, Bei‐Bei, Yu, Qian, Netea, Mihai G., Tang, Ren‐Xian, Zheng, Kui‐Yang · 2020 · Hepatology
- Zinc promotes microbial p-coumaric acid production that protects against cholestatic liver injuryDongping Li, Meijuan Wan, Lan-Feng Xue, Zhelin Zhang, Yifeng Qiu, Fengyi Mei, Niexing Tang, Chunxiao Yu, Yu Yao, Tianqi Chen et al. · 2024 · Cell Host & Microbe
- Keratin 7 expression in hepatic cholestatic diseasesStratigoula Sakellariou, Constantinos Michaelides, Theodoros A. Voulgaris, Jiannis Vlachogiannakos, Emanuel K. Manesis, DINA G. TINIAKOS, Ioanna Kassiani Delladetsima · 2021 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
- Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver DiseaseThapa, Manoj, Tedesco, Dana, Gumber, Sanjeev, Elrod, Elizabeth J, Han, Jin-Hwan, Kitchens, William H, Magliocca, Joseph F, Adams, Andrew B, Grakoui, Arash · 2020 · The Journal of Immunology
- Chenodeoxycholic acid modulates cholestatic niche through FXR/Myc/P-selectin axis in liver endothelial cellsPeng Zhang, Xinying Li, Jinyuan Liang, Yuanwen Zheng, Yao Tong, Jing Shen, Yatai Chen, Penghu Han, Shuzheng Chu, Ruirui Liu et al. · 2025 · Nature Communications
- Genetic Determinants of CholestasisGideon Morris Hirschfield · 2013 · Clinics in Liver Disease
- Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic miceRongjun Jia, Fan Yang, Pengfei Yan, Liman Ma, Longfei Yang, Lihua Li · 2021 · Free Radical Biology and Medicine
- Pivotal roles of Kupffer cells in the progression and regression of DDC-induced chronic cholangiopathyLeila Jemail, Masashi Miyao, Hirokazu Kotani, Chihiro Kawai, Hirozo Minami, Hitoshi Abiru, Keiji Tamaki · 2018 · Scientific Reports
- Therapeutic Role of Bile Acids and Nuclear Receptor Agonists in Fibrosing CholangiopathiesMichael Trauner, Emina Halilbasic, Lili Kazemi-Shirazi, Christian Kienbacher, Katharina Staufer, Stefan Traussnigg, Harald Hofer · 2014 · Digestive Diseases
- Pathological Contribution of Extracellular Vesicles and Their MicroRNAs to Progression of Chronic Liver DiseaseChanbin Lee, Jinsol Han, Youngmi Jung · 2022 · Biology
- Identification of a candidate stem cell in human gallbladderRohan Manohar, Yaming Li, Hélène Fohrer-Ting, Lynda J. Guzik, Donna Beer Stolz, Uma R. Chandran, William A. LaFramboise, Eric Lagasse · 2015 · Stem Cell Research
- Identification and expansion of a unique stem cell population from adult mouse gallbladderRohan Manohar, Junji Komori, Lynda J. Guzik, Donna Beer Stolz, Uma Chandran, William A. LaFramboise, Eric Lagasse · 2011 · Hepatology
- Integrated systems toxicology approaches identified the possible involvement of ABC transporters pathway in erythromycin estolate-induced liver injury in ratXiaoyan Lu, Yu Tian, Xueping Lian, Yachao Jin, Tingting Jin, Qinqin Zhao, Bin Hu, Xiuping Shen, Xiaohui Fan · 2014 · Food and Chemical Toxicology
- Model Systems for Studying the Role of Canalicular Efflux Transporters in Drug-Induced Cholestatic Liver DiseaseBruno Stieger, Zaynab Mahdi · 2017 · Journal of Pharmaceutical Sciences
- Calprotectin in BileTorsten Voigtländer, Jenny Wlecke, Ahmed Abdelmoniem Negm, Henrike Lenzen, Michael Peter Manns, Tim Oliver Lankisch · 2014 · Journal of Clinical Gastroenterology
- Differential Regulation of Hepatic Organic Cation Transporter 1, Organic Anion-Transporting Polypeptide 1a4, Bile-Salt Export Pump, and Multidrug Resistance-Associated Protein 2 Transporter Expression in Lymphocyte-Deficient Mice Associates with Interleukin-6 ProductionConnor E. Bodeman, Anika L. Dzierlenga, Catherine M. Tally, Ryan M. Mulligan, April D. Lake, Nathan J. Cherrington, Susan C. McKarns · 2013 · Journal of Pharmacology and Experimental Therapeutics
- Insights into the pharmacological and therapeutic effects of apigenin in liver injuries and diseasesChenchen Bi, Wenwen Han, Jingru Yu, Huafang Zhang, Guiying Xing, Zheng Liu · 2023 · Heliyon
- Emerging drugs for the treatment of Primary Biliary CholangitisAhmad Hassan Ali, James H. Tabibian, Elizabeth J. Carey, Keith D. Lindor · 2016 · Expert Opinion on Emerging Drugs
- Total bile acid-to-cholesterol ratio as a novel noninvasive marker for significant liver fibrosis and cirrhosis in patients with non-cholestatic chronic hepatitis B virus infectionLiting Yan, Lili Wang, Jia Yao, Yating Yang, Xiaorong Mao, Wei Yue, Yongwu Mao, Wei Zhou, Qing-Feng Chen, Yu Chen et al. · 2020 · Medicine
- Cholestasis-Associated Pulmonary Inflammation, Oxidative Stress, and Tissue Fibrosis: The Protective Role of the Biogenic Amine AgmatineMohammad Mehdi Ommati, Hossein Niknahad, Asma Najibi, Abdollah Arjmand, Sepideh Alidaee, Sahra Mazloomi, Parinaz Ahmadi, Alireza Ghiasvand, Maral Javadi, Jamal Yazdani et al. · 2023 · Pharmacology
- Management of Primary Sclerosing Cholangitis: Conventions and ControversiesNatasha Chandok, Gideon Morris Hirschfield · 2012 · Canadian Journal of Gastroenterology
- Effects of Hepatocyte CD14 Upregulation during Cholestasis on Endotoxin SensitivityMing-Huei Chou, Jiin‐Haur Chuang, Hock‐Liew Eng, Po-Chin Tsai, Chih‐Sung Hsieh, Hsiang-Chun Liu, Chiou-Huey Wang, Chih-Yun Lin, Tsun‐Mei Lin · 2012 · PLoS ONE
- Baohuoside I inhibits FXR signaling pathway to interfere with bile acid homeostasis via targeting ER α degradationZhen Zhou Zhao, Lulu Yang, Qiao-Lei Wang, Jinfa Du, Zu‐Guo Zheng, Yan Jiang, Ping Li, Hui‐Jun Li · 2022 · Cell Biology and Toxicology
- Distribution dynamics and functional importance of NHERF1 in regulation of Mrp-2 trafficking in hepatocytesSerhan Karvar, Jo Suda, Lixin Zhu, Don C. Rockey · 2014 · American Journal of Physiology-Cell Physiology
- Bile acids in cholestasis: Bad for the liver, not so good for the kidneySerge Erlinger · 2014 · Clinics and Research in Hepatology and Gastroenterology
- Gut microbiome in liver pathophysiology and cholestatic liver diseaseShengmin Yan, Xiao‐Ming Yin · 2021 · Liver Research
- A Guide to Pathophysiology, Signaling Pathways, and Preclinical Models of Liver Fibrosis.Mehonaz Sultana, Md Asrarul Islam, Rhema Khairnar, Sunil Kumar · 2025 · Molecular and Cellular Endocrinology
- Protective Effects of Peroxiredoxin 4 (PRDX4) on Cholestatic Liver InjuryJing Zhang, Xin Guo, Taiji Hamada, Seiya Yokoyama, Yuka Nakamura, Jianbo Zheng, Nozomu Kurose, Yasuhito Ishigaki, Hidetaka Uramoto, Akihide Tanimoto et al. · 2018 · International Journal of Molecular Sciences
- Cholestatic models induced by lithocholic acid and α‑naphthylisothiocyanate: Different etiological mechanisms for liver injury but shared JNK/STAT3 signalingGang-Ming Xu, Manyun Dai, Xiuting Zheng, Hante Lin, Aiming Liu, Julin Yang · 2020 · Molecular Medicine Reports
- The role of natural killer T cells in a mouse model with spontaneous bile duct inflammationElisabeth Schrumpf, Xiaojun Jiang, Sebastian Zeißig, Marion Julia Pollheimer, Jarl Andreas Anmarkrud, Corey Tan, Mark Adrian Exley, Tom H. Karlsen, Richard S. Blumberg, Espen Melum · 2017 · Physiological Reports
- Pterostilbene Alleviates Cholestasis by Promoting SIRT1 Activity in Hepatocytes and MacrophagesChuanrui Ma, Jiaqing Xiang, Guixiao Huang, Yaxi Zhao, Xinyu Wang, Han Wu, Kewei Jiang, Zhen Liang, Lin Kang, Guangyan Yang et al. · 2021 · Frontiers in Pharmacology
- Exploration of the Molecular Basis of Forsythia Fruit in the Prevention and Treatment of Cholestatic Liver Injury through Network Pharmacology and Molecular DockingKe Fu, Yanzhi Li, Shu Dai, Yunxia Li · 2023 · Nutrients
- Mitochondrial Alpha-Keto Acid Dehydrogenase Complexes: Recent Developments on Structure and Function in Health and DiseaseEszter Szabó, Bálint Nagy, András Czajlik, Tímea Komlódi, Olivér Ozohanics, László Tretter, Attila Ambrus · 2024 · Sub-cellular biochemistry/Subcellular biochemistry
- Fasting reduces liver fibrosis in a mouse model for chronic cholangiopathiesAleksandar Sokolović, Cindy P. A. A. van Roomen, Roelof Ottenhoff, Saskia S. Scheij, Johan K. Hiralall, Nike Claessen, Jan Aten, Ronald P.J. Oude Elferink, Albert Kornelis Groen, Milka Sokolović · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Arachidonic acid enhances hepatocyte bile acid uptake and alleviates cholestatic liver disease by upregulating OATP1 expressionYanlu Ma, Chen Zou, Yilan Yang, Miao Fang, Yun‐Feng Guan, Jianqi Sun, Yueqiu Gao, Zhi Shang, Xin Zhang · 2024 · Food & Function
- Prognostic indicators in primary biliary cirrhosis: significance of revised IAHG (International Autoimmune Hepatitis Group) scoreHo Eun Jung, Jae Young Jang, Soung Won Jeong, Jin Nyoung Kim, Hee Yoon Jang, Yun Ju Cho, Sung Ae Woo, Sae Hwan Lee, Sang Gyune Kim, Sang‐Woo Cha et al. · 2012 · Clinical and Molecular Hepatology
- Mouse precision-cut liver slices as an ex vivo model to study drug-induced cholestasisRuby E. H. Karsten, Nikolaas Krijnen, Walid Maho, Hjalmar P. Permentier, Elisabeth M. J. Verpoorte, Peter Olinga · 2022 · Archives of Toxicology
- Dimethyl fumarate attenuates cholestatic liver injury by activating the NRF2 and FXR pathways and suppressing NLRP3/GSDMD signaling in miceZiqian Xu, Wan Tang, Qiaoling Xie, Xinyu Cao, Mengni Zhang, Xiaoxun Zhang, Jin Chai · 2023 · Experimental Cell Research
- 9-cis-retinoic acid elevates MRP3 expression by inhibiting sumoylation of RXRα to alleviate cholestatic liver injuryZhiqing Yuan, Guiyang Wang, Junwen Qu, Xiaopeng Wang, Kewei Li · 2018 · Biochemical and Biophysical Research Communications
- Identification of global mRNA expression profiles and comprehensive bioinformatic analyses of abnormally expressed genes in cholestatic liver diseaseJie Lena Sun, Jing Wang, Na Zhang, Renjun Yang, Keyang Chen, Derun Kong · 2019 · Gene
- Nerve growth factor induced farnesoid X receptor upregulation modulates autophagy flux and protects hepatocytes in cholestatic liversMing‐Shian Tsai, Hui-Ming Lee, Shih-Che Huang, Cheuk‐Kwan Sun, Ting-Chia Chiu, Po‐Han Chen, Yu‐Chun Lin, Tzu‐Min Hung, Po‐Huang Lee, Y. H. Kao · 2020 · Archives of Biochemistry and Biophysics
- Racial or ethnic differences on treatment adherence and persistence among patients with inflammatory bowel diseases initiated with biologic therapiesQian Cai, Zhijie Ding, Alex Z. Fu, Aarti A. Patel · 2022 · BMC Gastroenterology
- The protective effect of forsythiaside A on 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestatic liver injury in mice: Based on targeted metabolomics and molecular biology technologyKe Fu, Shu Dai, Yanzhi Li, Cheng Ma, Xinyan Xue, Shenglin Zhang, Cheng Wang, Honglin Zhou, Yafang Zhang, Yunxia Li · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Conventional type 1 dendritic cells are essential for the development of primary biliary cholangitisDebby Reuveni, Siwar Assi, Yael Gore, Eli Brazowski, Patrick S.C. Leung, Tali Shalit, Merrill Eric Gershwin, Ehud Zigmond · 2024 · Liver International
- Structural Basis of Novel Bile Acid-Based Modulators of FXRDannielle Kydd-Sinclair, Gemma Packer, Alex Weymouth‐Wilson, Kimberly A. Watson · 2025 · Journal of Molecular Biology
- Phosphorylation dynamics of radixin in hypoxia-induced hepatocyte injuryJo Suda, Don C. Rockey, Serhan Karvar · 2014 · American Journal of Physiology-Gastrointestinal and Liver Physiology
- Protective Effect of Rhus chinensis Mill. Fruits on 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine-Induced Cholestasis in Mice via Ameliorating Oxidative Stress and InflammationYilin Sun, Shengbao Cai, Yuanyue Zhang, Nan Ma, Junjie Yi, Xiaosong Hu, Tao Wang · 2022 · Nutrients
- Prevention of Cell Growth by Suppression of Villin Expression in Lithocholic Acid-Stimulated HepG2 CellsMunetaka Ozeki, Wulamujiang Aini, Aya Miyagawa‐Hayashino, Keiji Tamaki · 2018 · Journal of Histochemistry & Cytochemistry
- Clinical profile and outcome of primary sclerosing cholangitis: A single-centre experience from western IndiaPratik Tibdewal, Pratin Bhatt, Abhinav Jain, Deepak Kumar Gupta, Shobna J. Bhatia, Akash Shukla · 2019 · Indian Journal of Gastroenterology
- Dysregulation of Circulating FGF19 and Bile Acids in Primary Biliary Cholangitis-Autoimmune Hepatitis Overlap SyndromeZhan-Yi Li, Yu Liu, Fang-Ji Yang, Jia-Hui Pang, Yuan-Kai Wu, Y. Chong, Xiang-Yong Li · 2020 · BioMed Research International
- Predicting and preventing autoimmunity: the case of anti-mitochondrial antibodiesMałgorzata Milkiewicz, Llorenç Caballería, Daniel S. Smyk, Piotr Milkiewicz · 2012 · Autoimmunity Highlights
- Role for mycobacterial infection in pathogenesis of primary biliary cirrhosis?Daniel S. Smyk · 2012 · World Journal of Gastroenterology
- Autophagy – another piece of the puzzle towards understanding primary biliary cirrhosis?Stan F.J. van de Graaf, Ulrich H. Beuers · 2014 · Liver International
- The External Validation of GLOBE and UK-PBC Risk Scores for Predicting Ursodeoxycholic Acid Treatment Response in a Large U.S. Cohort of Primary Biliary Cholangitis PatientsAna Marenco‐Flores, Natalia Rojas-Amaris, Tamara F. Kahan, Leandro Sierra, Romelia Barba, Esli Medina‐Morales, Daniela Goyes, Vilas R. Patwardhan, Alan Bonder · 2024 · Journal of Clinical Medicine
- Asperdoles A–N: Indole Diterpenoids from the Endolichenic Fungus Aspergillus sp. TJ403-YJ22Jun Yao, Chenyang Wang, Hanxiao Zeng, Yu Cao, Xianjie Qiu, Wenqi Li, Yongzhi Lu, Jinsai Shang, Jianping Wang, Yonghui Zhang et al. · 2025 · Journal of Natural Products
- Molecular basis of progressive familial intrahepatic cholestasis 3. A proteomics studyLaura Guerrero, Lorena Carmona‐Rodríguez, Fátima Milhano Santos, Sergio Ciordia, Luiz Stark Aroeira, Loreto Hierro, Pablo Pérez‐Montero, David Vicent, Fernando José Corrales · 2024 · BioFactors
- Global Epidemiology of Cirrhosis in WomenGabrielle Jutras, Jennifer A. Flemming · 2024 · The American Journal of Gastroenterology
- Functional roles of gut bacteria imbalance in cholangiopathiesKeisaku Sato, Fanyin Meng, Giammarco Fava, Shannon S. Glaser, Gianfranco D. Alpini · 2018 · Liver Research
- Therapeutic action against chronic cholestatic liver injury by low-dose fenofibrate involves anti-chemotaxis via JNK–AP1–CCL2/CXCL2 signalingManyun Dai, Julin Yang, Yishuang Luo, Liping Xu, Haoyue Zhang, Gang-Ming Xu, Aiming Liu · 2020 · Pharmacological Reports
- Mammalian Target of Rapamycin Complex 2 Signaling Is Required for Liver Regeneration in a Cholestatic Liver Injury Murine ModelYi Zhou, Meng Michelle Xu, Liu Pin, Bin-yong Liang, Manning Qian, Haichuan Wang, Xinhua Song, Pranavanand Nyshadham, Li Che, Diego Francesco Calvisi et al. · 2020 · American Journal Of Pathology
- Pregnane X receptor as a therapeutic target for cholestatic liver injuryHuan Lan, Ying Zhang, Minqi Fan, Bingxin Wu, Caiyan Wang · 2023 · Drug Metabolism Reviews
- Engineered FGF19ΔKLB protects against intrahepatic cholestatic liver injury in ANIT-induced and Mdr2-/- mice modelLu Shi, Tiantian Zhao, Lei Huang, Xiaomin Pan, Tianzhen Wu, Xin Feng, Taoli Chen, Jiamin Wu, Jianlou Niu · 2023 · BMC Biotechnology
- Carnosine Mitigates Biomarkers of Oxidative Stress, Improves Mitochondrial Function, and Alleviates Histopathological Alterations in the Renal Tissue of Cholestatic RatsOmid Farshad, Mohammad Mehdi Ommati, Jale Yüzügülen, Akram Jamshidzadeh, Khadijeh Mousavi, Zahra Ahmadi, Negar Azarpira, Hasti Ghaffari, Asma Najibi, Marzieh Shafaghat et al. · 2020 · Pharmaceutical Sciences
- Hepatoprotective effect of astaxanthin against cholestasis liver fibrosis induced by bile duct ligation in adult Wistar ratsAzadeh Laderian, Maedeh Ghasemi, Pejman Mortazavi, Zahra Mousavi, Mahsa Ale‐Ebrahim · 2024 · Journal of Biochemical and Molecular Toxicology
- Autoimmunerkrankungen der LeberNadine Pannicke, Christoph Schramm, Ansgar Wilhelm Lohse · 2012 · Der Internist
- Molecular Insights of Cholestasis in MDR2 Knockout Murine Liver OrganoidsIrene Blázquez‐García, Laura Guerrero, Cristina Cacho-Navas, Nabil Djouder, Jaime Millán, Alberto Paradela, Lorena Carmona‐Rodríguez, Fernando José Corrales · 2024 · Journal of Proteome Research
- A rare cause of a cholestatic jaundice in a North African teenagerPhilipp Schreiner, Bruno Stieger, Valérie A. McLin, Anne‐Laure Rougemont, Verena Keitel, Carola Dröge, Beat Müllhaupt · 2019 · Liver International
- Substance-P prevents the cholestatic liver injury by regulating inflammatory responsesSuna Kim, Hyun Sook Hong · 2021 · Peptides
- Pharmacology of IridoidsBiswanath Dinda · 2019 · Springer eBooks
- Myocyte Enhancer Factor 2A Contributes to the TGF-β1-Mediated Cholangiocyte Epithelial to Mesenchymal Transition and Senescence in Cholestatic Liver FibrosisGuangxi Zhou, Fei Hou, Heng He, Yuan Xue, Yibo Wang, Xueying Chen, Fengqin Zhu · 2022 · Frontiers in Bioscience-Landmark
- The Role of hsa-miR-125b-5p Interaction with S1P/Ceramide Axis in the Potential Development of Inflammation-Associated Colon Cancer in Primary Sclerosing CholangitisJoanna Abramczyk, Małgorzata Milkiewicz, Bartosz Huła, Piotr Milkiewicz, Agnieszka Kempińska‐Podhorodecka · 2023 · International Journal of Molecular Sciences
- Therapeutic approaches for cholestatic liver diseases: the role of nitric oxide pathwayNaser‐Aldin Lashgari, Danial Khayatan, Nazanin Momeni Roudsari, Saeideh Momtaz, Ahmad Reza Dehpour, Amir Hossein Abdolghaffari · 2023 · Naunyn-Schmiedeberg s Archives of Pharmacology
- Lignans are the main active components of Schisandrae Chinensis Fructus for liver disease treatment: a reviewKe Fu, Shu Dai, Cheng Ma, Yafang Zhang, Shenglin Zhang, Cheng Wang, Lihong Gong, Honglin Zhou, Yunxia Li · 2023 · Food Science and Human Wellness
- Immunological diseases of the pancreatico-hepatobiliary system: update on etiopathogenesis and cross-sectional imaging findingsDeepak Kumar Garg, Arpit M Nagar, Shaile Philips, Naoki Takahashi, Srinivasa R. Prasad, Krishna Shanbhogue, Dushyant V. Sahani · 2011 · Abdominal Imaging
- Ursodeoxycholic Acid Influences the Expression of p27kip1 but Not FoxO1 in Patients with Non-Cirrhotic Primary Biliary CirrhosisMałgorzata Milkiewicz, Justyna Kopycińska, Agnieszka Kempińska‐Podhorodecka, Tara L. Haas, Dimitrios Petrou Bogdanos, Elwyn Elias, Piotr Milkiewicz · 2014 · Journal of Immunology Research
- Gentamicin alleviates cholestatic liver injury by decreasing gut microbiota-associated bile salt hydrolase activity in ratsYanrong Ma, Huan Wang, Jinru Yang, Mingyan Xin, Xinan Wu · 2023 · European Journal of Pharmacology