Pathogenesis of cholestatic liver disease and therapeutic approaches

Hirschfield, Gideon M., Heathcote, E. Jenny, Gershwin, M. Eric·2010·Gastroenterology

Cited by (286)

Items 101–200 of 286

  1. Cell-specific regulatory effects of CXCR2 on cholestatic liver injury
    Takanori Konishi, Rebecca M. Schuster, Holly S. Goetzman, Charles C. Caldwell, Alex B. Lentsch · 2019 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  2. Fetal androgen exposure is a determinant of adult male metabolic health
    Katarzyna J. Siemienowicz, Panagiotis Filis, Sophie Shaw, Alex Douglas, Jennifer L. Thomas, Sally Mulroy, Forbes A. Howie, Paul Fowler, William Colin Duncan, Mick T. Rae · 2019 · Scientific Reports
  3. A UPLC-MS/MS-based metabolomics analysis of the pharmacological mechanisms of rabdosia serra against cholestasis
    Kaihui Zhang, Yufeng Yao, Meiqi Wang, Fangle Liu, Qian Wang, Huanhuan Ma, Yuanyuan Xie, Yunxia Ma, Pengyu Dai, Chenchen Zhu et al. · 2021 · Phytomedicine
  4. The Pyruvate Dehydrogenase Complex and Related Assemblies in Health and Disease
    Olwyn Byron, John Gordon LINDSAY · 2017 · Sub-cellular biochemistry/Subcellular biochemistry
  5. Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing Cholangitis
    Matteo Tardelli, Francesca Virginia Bruschi, Claudia Daniela Fuchs, Thierry Claudel, Nicole Auer, Victoria Kunczer, Maximilian Baumgartner, Onne A. H. O. Ronda, Henkjan J. Verkade, Tatjana Stojaković et al. · 2019 · Hepatology
  6. Serum cell death biomarkers for prediction of liver fibrosis and poor prognosis in primary biliary cirrhosis
    Sekiguchi, Tomohiro, Umemura, Takeji, Fujimori, Naoyuki, Shibata, Soichiro, Ichikawa, Yuki, Kimura, Takefumi, Joshita, Satoru, Komatsu, Michiharu, Matsumoto, Akihiro, Tanaka, Eiji et al. · 2015 · PLOS ONE
  7. Recent advances in three-dimensional cell culturing to assess liver function and dysfunction: from a drug biotransformation and toxicity perspective
    Carlemi Calitz, Josias Hendrik Hamman, Stephen J. Fey, Krzysztof Wrzesinski, Chrisna Gouws · 2018 · Toxicology Mechanisms and Methods
  8. Tutorial Review for Understanding of Cholangiopathy
    Yasuni Nakanuma · 2011 · International Journal of Hepatology
  9. Structure, Function, and Responses to Injury
    James M. Crawford, Paulette Bioulac‐Sage, Prodromos Hytiroglou · 2017 · Elsevier eBooks
  10. Pregnane X receptor and constitutive androstane receptor modulate differently CYP3A-mediated metabolism in early- and late-stage cholestasis
    Daniela Gabbia, Arianna Dalla Pozza, Laura Albertoni, Roberta Lazzari, Giorgia Zigiotto, Maria Carrara, Vincenzo Baldo, Tatjana Baldovin, Annarosa Floreani, Sara De Martin · 2017 · World Journal of Gastroenterology
  11. Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis: an Update on MR Imaging Findings with Recent Developments
    Jelena Djokić Kovač, Marc‐André Weber · 2016 · Journal of Gastrointestinal and Liver Diseases
  12. Genetics in PBC: What Do the “Risk Genes” Teach Us?
    Gideon Morris Hirschfield, Katherine A. Siminovitch · 2014 · Clinical Reviews in Allergy & Immunology
  13. Metabolic Regulation of Macrophages by SIRT1 Determines Activation During Cholestatic Liver Disease in Mice
    Anna Isaacs‐Ten, Mar Moreno‐Gonzalez, Caitlin Bone, André Märtens, Federico Bernuzzi, Tobias Ludwig, Charlotte Hellmich, Karsten Hiller, Stuart A. Rushworth, Naiara Beraza · 2021 · Cellular and Molecular Gastroenterology and Hepatology
  14. TNF-α/IL-1β-licensed hADSCs alleviate cholestatic liver injury and fibrosis in mice via COX-2/PGE2 pathway
    Luan, Xiaoyu, Chen, Peng, Li, Yaxin, Yuan, Xinying, Miao, Longyu, Zhang, Pengyu, Cao, Qilong, Song, Xiaomin, Di, Guohu · 2023 · Stem Cell Research & Therapy
  15. Characterization of Ursodeoxycholic and Norursodeoxycholic Acid as Substrates of the Hepatic Uptake Transporters OATP 1B1, OATP 1B3, OATP 2B1 and NTCP
    Jörg König, Sabine Klatt, Karin Dilger, Martin F. Fromm · 2012 · Basic & Clinical Pharmacology & Toxicology
  16. Na+/H+ exchanger regulatory factor 1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injury
    Man Li, Albert Mennone, Carol J. Soroka, Lee R. Hagey, Xinshou Ouyang, Edward J. Weinman, James Lorenzen Boyer · 2015 · Hepatology
  17. The Liver, Oxidative Stress, and Antioxidants
    Sael Casas‐Grajales, Pablo Muriel · 2017 · Elsevier eBooks
  18. Diagnostic Approach to the Patient with Jaundice
    James M. Winger, Aaron J. Michelfelder · 2011 · Primary Care Clinics in Office Practice
  19. Targeted Metabolomics Reveals a Protective Role for Basal PPARα in Cholestasis Induced by α-Naphthylisothiocyanate
    Manyun Dai, Huiying Hua, Hante Lin, Gang-Ming Xu, Xiaowei Hu, Fei Li, Frank J. Gonzalez, Aiming Liu, Julin Yang · 2018 · Journal of Proteome Research
  20. Biliary epithelium: A neuroendocrine compartment in cholestatic liver disease
    Laurent Ehrlich, Marinda Scrushy, Fanyin Meng, Terry C. Lairmore, Gianfranco D. Alpini, Shannon S. Glaser · 2018 · Clinics and Research in Hepatology and Gastroenterology
  21. Laboratory assessment of liver function and injury in children
    Vicky L. Ng · 2014 · Cambridge University Press eBooks
  22. Sortilin 1 Loss-of-Function Protects Against Cholestatic Liver Injury by Attenuating Hepatic Bile Acid Accumulation in Bile Duct Ligated Mice
    Jibiao Li, Benjamin Leeland Woolbright, Wen Ming Zhao, Yifeng Wang, David J. Matye, Bruno Hagenbuch, Hartmut Jaeschke, Tiangang Li · 2017 · Toxicological Sciences
  23. Current therapies and novel approaches for biliary diseases
    Indu G. Rajapaksha, Peter Angus, Chandana B. Herath · 2019 · World Journal of Gastrointestinal Pathophysiology
  24. The Enterokine Fibroblast Growth Factor 15/19 in Bile Acid Metabolism
    Marica Cariello, Marilidia Piglionica, Raffaella Maria Gadaleta, Antonio Moschetta · 2019 · Handbook of experimental pharmacology
  25. Roles of Trained Immunity in the Pathogenesis of Cholangiopathies: A Therapeutic Target
    Yan, Chao, Koda, Stephane, Wu, Jing, Zhang, Bei‐Bei, Yu, Qian, Netea, Mihai G., Tang, Ren‐Xian, Zheng, Kui‐Yang · 2020 · Hepatology
  26. Zinc promotes microbial p-coumaric acid production that protects against cholestatic liver injury
    Dongping Li, Meijuan Wan, Lan-Feng Xue, Zhelin Zhang, Yifeng Qiu, Fengyi Mei, Niexing Tang, Chunxiao Yu, Yu Yao, Tianqi Chen et al. · 2024 · Cell Host & Microbe
  27. Keratin 7 expression in hepatic cholestatic diseases
    Stratigoula Sakellariou, Constantinos Michaelides, Theodoros A. Voulgaris, Jiannis Vlachogiannakos, Emanuel K. Manesis, DINA G. TINIAKOS, Ioanna Kassiani Delladetsima · 2021 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  28. Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver Disease
    Thapa, Manoj, Tedesco, Dana, Gumber, Sanjeev, Elrod, Elizabeth J, Han, Jin-Hwan, Kitchens, William H, Magliocca, Joseph F, Adams, Andrew B, Grakoui, Arash · 2020 · The Journal of Immunology
  29. Chenodeoxycholic acid modulates cholestatic niche through FXR/Myc/P-selectin axis in liver endothelial cells
    Peng Zhang, Xinying Li, Jinyuan Liang, Yuanwen Zheng, Yao Tong, Jing Shen, Yatai Chen, Penghu Han, Shuzheng Chu, Ruirui Liu et al. · 2025 · Nature Communications
  30. Genetic Determinants of Cholestasis
    Gideon Morris Hirschfield · 2013 · Clinics in Liver Disease
  31. Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice
    Rongjun Jia, Fan Yang, Pengfei Yan, Liman Ma, Longfei Yang, Lihua Li · 2021 · Free Radical Biology and Medicine
  32. Pivotal roles of Kupffer cells in the progression and regression of DDC-induced chronic cholangiopathy
    Leila Jemail, Masashi Miyao, Hirokazu Kotani, Chihiro Kawai, Hirozo Minami, Hitoshi Abiru, Keiji Tamaki · 2018 · Scientific Reports
  33. Therapeutic Role of Bile Acids and Nuclear Receptor Agonists in Fibrosing Cholangiopathies
    Michael Trauner, Emina Halilbasic, Lili Kazemi-Shirazi, Christian Kienbacher, Katharina Staufer, Stefan Traussnigg, Harald Hofer · 2014 · Digestive Diseases
  34. Pathological Contribution of Extracellular Vesicles and Their MicroRNAs to Progression of Chronic Liver Disease
    Chanbin Lee, Jinsol Han, Youngmi Jung · 2022 · Biology
  35. Identification of a candidate stem cell in human gallbladder
    Rohan Manohar, Yaming Li, Hélène Fohrer-Ting, Lynda J. Guzik, Donna Beer Stolz, Uma R. Chandran, William A. LaFramboise, Eric Lagasse · 2015 · Stem Cell Research
  36. Identification and expansion of a unique stem cell population from adult mouse gallbladder
    Rohan Manohar, Junji Komori, Lynda J. Guzik, Donna Beer Stolz, Uma Chandran, William A. LaFramboise, Eric Lagasse · 2011 · Hepatology
  37. Integrated systems toxicology approaches identified the possible involvement of ABC transporters pathway in erythromycin estolate-induced liver injury in rat
    Xiaoyan Lu, Yu Tian, Xueping Lian, Yachao Jin, Tingting Jin, Qinqin Zhao, Bin Hu, Xiuping Shen, Xiaohui Fan · 2014 · Food and Chemical Toxicology
  38. Model Systems for Studying the Role of Canalicular Efflux Transporters in Drug-Induced Cholestatic Liver Disease
    Bruno Stieger, Zaynab Mahdi · 2017 · Journal of Pharmaceutical Sciences
  39. Calprotectin in Bile
    Torsten Voigtländer, Jenny Wlecke, Ahmed Abdelmoniem Negm, Henrike Lenzen, Michael Peter Manns, Tim Oliver Lankisch · 2014 · Journal of Clinical Gastroenterology
  40. Differential Regulation of Hepatic Organic Cation Transporter 1, Organic Anion-Transporting Polypeptide 1a4, Bile-Salt Export Pump, and Multidrug Resistance-Associated Protein 2 Transporter Expression in Lymphocyte-Deficient Mice Associates with Interleukin-6 Production
    Connor E. Bodeman, Anika L. Dzierlenga, Catherine M. Tally, Ryan M. Mulligan, April D. Lake, Nathan J. Cherrington, Susan C. McKarns · 2013 · Journal of Pharmacology and Experimental Therapeutics
  41. Insights into the pharmacological and therapeutic effects of apigenin in liver injuries and diseases
    Chenchen Bi, Wenwen Han, Jingru Yu, Huafang Zhang, Guiying Xing, Zheng Liu · 2023 · Heliyon
  42. Emerging drugs for the treatment of Primary Biliary Cholangitis
    Ahmad Hassan Ali, James H. Tabibian, Elizabeth J. Carey, Keith D. Lindor · 2016 · Expert Opinion on Emerging Drugs
  43. Total bile acid-to-cholesterol ratio as a novel noninvasive marker for significant liver fibrosis and cirrhosis in patients with non-cholestatic chronic hepatitis B virus infection
    Liting Yan, Lili Wang, Jia Yao, Yating Yang, Xiaorong Mao, Wei Yue, Yongwu Mao, Wei Zhou, Qing-Feng Chen, Yu Chen et al. · 2020 · Medicine
  44. Cholestasis-Associated Pulmonary Inflammation, Oxidative Stress, and Tissue Fibrosis: The Protective Role of the Biogenic Amine Agmatine
    Mohammad Mehdi Ommati, Hossein Niknahad, Asma Najibi, Abdollah Arjmand, Sepideh Alidaee, Sahra Mazloomi, Parinaz Ahmadi, Alireza Ghiasvand, Maral Javadi, Jamal Yazdani et al. · 2023 · Pharmacology
  45. Management of Primary Sclerosing Cholangitis: Conventions and Controversies
    Natasha Chandok, Gideon Morris Hirschfield · 2012 · Canadian Journal of Gastroenterology
  46. Effects of Hepatocyte CD14 Upregulation during Cholestasis on Endotoxin Sensitivity
    Ming-Huei Chou, Jiin‐Haur Chuang, Hock‐Liew Eng, Po-Chin Tsai, Chih‐Sung Hsieh, Hsiang-Chun Liu, Chiou-Huey Wang, Chih-Yun Lin, Tsun‐Mei Lin · 2012 · PLoS ONE
  47. Baohuoside I inhibits FXR signaling pathway to interfere with bile acid homeostasis via targeting ER α degradation
    Zhen Zhou Zhao, Lulu Yang, Qiao-Lei Wang, Jinfa Du, Zu‐Guo Zheng, Yan Jiang, Ping Li, Hui‐Jun Li · 2022 · Cell Biology and Toxicology
  48. Distribution dynamics and functional importance of NHERF1 in regulation of Mrp-2 trafficking in hepatocytes
    Serhan Karvar, Jo Suda, Lixin Zhu, Don C. Rockey · 2014 · American Journal of Physiology-Cell Physiology
  49. Bile acids in cholestasis: Bad for the liver, not so good for the kidney
    Serge Erlinger · 2014 · Clinics and Research in Hepatology and Gastroenterology
  50. Gut microbiome in liver pathophysiology and cholestatic liver disease
    Shengmin Yan, Xiao‐Ming Yin · 2021 · Liver Research
  51. A Guide to Pathophysiology, Signaling Pathways, and Preclinical Models of Liver Fibrosis.
    Mehonaz Sultana, Md Asrarul Islam, Rhema Khairnar, Sunil Kumar · 2025 · Molecular and Cellular Endocrinology
  52. Protective Effects of Peroxiredoxin 4 (PRDX4) on Cholestatic Liver Injury
    Jing Zhang, Xin Guo, Taiji Hamada, Seiya Yokoyama, Yuka Nakamura, Jianbo Zheng, Nozomu Kurose, Yasuhito Ishigaki, Hidetaka Uramoto, Akihide Tanimoto et al. · 2018 · International Journal of Molecular Sciences
  53. Cholestatic models induced by lithocholic acid and α‑naphthylisothiocyanate: Different etiological mechanisms for liver injury but shared JNK/STAT3 signaling
    Gang-Ming Xu, Manyun Dai, Xiuting Zheng, Hante Lin, Aiming Liu, Julin Yang · 2020 · Molecular Medicine Reports
  54. The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation
    Elisabeth Schrumpf, Xiaojun Jiang, Sebastian Zeißig, Marion Julia Pollheimer, Jarl Andreas Anmarkrud, Corey Tan, Mark Adrian Exley, Tom H. Karlsen, Richard S. Blumberg, Espen Melum · 2017 · Physiological Reports
  55. Pterostilbene Alleviates Cholestasis by Promoting SIRT1 Activity in Hepatocytes and Macrophages
    Chuanrui Ma, Jiaqing Xiang, Guixiao Huang, Yaxi Zhao, Xinyu Wang, Han Wu, Kewei Jiang, Zhen Liang, Lin Kang, Guangyan Yang et al. · 2021 · Frontiers in Pharmacology
  56. Exploration of the Molecular Basis of Forsythia Fruit in the Prevention and Treatment of Cholestatic Liver Injury through Network Pharmacology and Molecular Docking
    Ke Fu, Yanzhi Li, Shu Dai, Yunxia Li · 2023 · Nutrients
  57. Mitochondrial Alpha-Keto Acid Dehydrogenase Complexes: Recent Developments on Structure and Function in Health and Disease
    Eszter Szabó, Bálint Nagy, András Czajlik, Tímea Komlódi, Olivér Ozohanics, László Tretter, Attila Ambrus · 2024 · Sub-cellular biochemistry/Subcellular biochemistry
  58. Fasting reduces liver fibrosis in a mouse model for chronic cholangiopathies
    Aleksandar Sokolović, Cindy P. A. A. van Roomen, Roelof Ottenhoff, Saskia S. Scheij, Johan K. Hiralall, Nike Claessen, Jan Aten, Ronald P.J. Oude Elferink, Albert Kornelis Groen, Milka Sokolović · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  59. Arachidonic acid enhances hepatocyte bile acid uptake and alleviates cholestatic liver disease by upregulating OATP1 expression
    Yanlu Ma, Chen Zou, Yilan Yang, Miao Fang, Yun‐Feng Guan, Jianqi Sun, Yueqiu Gao, Zhi Shang, Xin Zhang · 2024 · Food & Function
  60. Prognostic indicators in primary biliary cirrhosis: significance of revised IAHG (International Autoimmune Hepatitis Group) score
    Ho Eun Jung, Jae Young Jang, Soung Won Jeong, Jin Nyoung Kim, Hee Yoon Jang, Yun Ju Cho, Sung Ae Woo, Sae Hwan Lee, Sang Gyune Kim, Sang‐Woo Cha et al. · 2012 · Clinical and Molecular Hepatology
  61. Mouse precision-cut liver slices as an ex vivo model to study drug-induced cholestasis
    Ruby E. H. Karsten, Nikolaas Krijnen, Walid Maho, Hjalmar P. Permentier, Elisabeth M. J. Verpoorte, Peter Olinga · 2022 · Archives of Toxicology
  62. Dimethyl fumarate attenuates cholestatic liver injury by activating the NRF2 and FXR pathways and suppressing NLRP3/GSDMD signaling in mice
    Ziqian Xu, Wan Tang, Qiaoling Xie, Xinyu Cao, Mengni Zhang, Xiaoxun Zhang, Jin Chai · 2023 · Experimental Cell Research
  63. 9-cis-retinoic acid elevates MRP3 expression by inhibiting sumoylation of RXRα to alleviate cholestatic liver injury
    Zhiqing Yuan, Guiyang Wang, Junwen Qu, Xiaopeng Wang, Kewei Li · 2018 · Biochemical and Biophysical Research Communications
  64. Identification of global mRNA expression profiles and comprehensive bioinformatic analyses of abnormally expressed genes in cholestatic liver disease
    Jie Lena Sun, Jing Wang, Na Zhang, Renjun Yang, Keyang Chen, Derun Kong · 2019 · Gene
  65. Nerve growth factor induced farnesoid X receptor upregulation modulates autophagy flux and protects hepatocytes in cholestatic livers
    Ming‐Shian Tsai, Hui-Ming Lee, Shih-Che Huang, Cheuk‐Kwan Sun, Ting-Chia Chiu, Po‐Han Chen, Yu‐Chun Lin, Tzu‐Min Hung, Po‐Huang Lee, Y. H. Kao · 2020 · Archives of Biochemistry and Biophysics
  66. Racial or ethnic differences on treatment adherence and persistence among patients with inflammatory bowel diseases initiated with biologic therapies
    Qian Cai, Zhijie Ding, Alex Z. Fu, Aarti A. Patel · 2022 · BMC Gastroenterology
  67. The protective effect of forsythiaside A on 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestatic liver injury in mice: Based on targeted metabolomics and molecular biology technology
    Ke Fu, Shu Dai, Yanzhi Li, Cheng Ma, Xinyan Xue, Shenglin Zhang, Cheng Wang, Honglin Zhou, Yafang Zhang, Yunxia Li · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  68. Conventional type 1 dendritic cells are essential for the development of primary biliary cholangitis
    Debby Reuveni, Siwar Assi, Yael Gore, Eli Brazowski, Patrick S.C. Leung, Tali Shalit, Merrill Eric Gershwin, Ehud Zigmond · 2024 · Liver International
  69. Structural Basis of Novel Bile Acid-Based Modulators of FXR
    Dannielle Kydd-Sinclair, Gemma Packer, Alex Weymouth‐Wilson, Kimberly A. Watson · 2025 · Journal of Molecular Biology
  70. Phosphorylation dynamics of radixin in hypoxia-induced hepatocyte injury
    Jo Suda, Don C. Rockey, Serhan Karvar · 2014 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  71. Protective Effect of Rhus chinensis Mill. Fruits on 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine-Induced Cholestasis in Mice via Ameliorating Oxidative Stress and Inflammation
    Yilin Sun, Shengbao Cai, Yuanyue Zhang, Nan Ma, Junjie Yi, Xiaosong Hu, Tao Wang · 2022 · Nutrients
  72. Prevention of Cell Growth by Suppression of Villin Expression in Lithocholic Acid-Stimulated HepG2 Cells
    Munetaka Ozeki, Wulamujiang Aini, Aya Miyagawa‐Hayashino, Keiji Tamaki · 2018 · Journal of Histochemistry & Cytochemistry
  73. Clinical profile and outcome of primary sclerosing cholangitis: A single-centre experience from western India
    Pratik Tibdewal, Pratin Bhatt, Abhinav Jain, Deepak Kumar Gupta, Shobna J. Bhatia, Akash Shukla · 2019 · Indian Journal of Gastroenterology
  74. Dysregulation of Circulating FGF19 and Bile Acids in Primary Biliary Cholangitis-Autoimmune Hepatitis Overlap Syndrome
    Zhan-Yi Li, Yu Liu, Fang-Ji Yang, Jia-Hui Pang, Yuan-Kai Wu, Y. Chong, Xiang-Yong Li · 2020 · BioMed Research International
  75. Predicting and preventing autoimmunity: the case of anti-mitochondrial antibodies
    Małgorzata Milkiewicz, Llorenç Caballería, Daniel S. Smyk, Piotr Milkiewicz · 2012 · Autoimmunity Highlights
  76. Role for mycobacterial infection in pathogenesis of primary biliary cirrhosis?
    Daniel S. Smyk · 2012 · World Journal of Gastroenterology
  77. Autophagy – another piece of the puzzle towards understanding primary biliary cirrhosis?
    Stan F.J. van de Graaf, Ulrich H. Beuers · 2014 · Liver International
  78. The External Validation of GLOBE and UK-PBC Risk Scores for Predicting Ursodeoxycholic Acid Treatment Response in a Large U.S. Cohort of Primary Biliary Cholangitis Patients
    Ana Marenco‐Flores, Natalia Rojas-Amaris, Tamara F. Kahan, Leandro Sierra, Romelia Barba, Esli Medina‐Morales, Daniela Goyes, Vilas R. Patwardhan, Alan Bonder · 2024 · Journal of Clinical Medicine
  79. Asperdoles A–N: Indole Diterpenoids from the Endolichenic Fungus Aspergillus sp. TJ403-YJ22
    Jun Yao, Chenyang Wang, Hanxiao Zeng, Yu Cao, Xianjie Qiu, Wenqi Li, Yongzhi Lu, Jinsai Shang, Jianping Wang, Yonghui Zhang et al. · 2025 · Journal of Natural Products
  80. Molecular basis of progressive familial intrahepatic cholestasis 3. A proteomics study
    Laura Guerrero, Lorena Carmona‐Rodríguez, Fátima Milhano Santos, Sergio Ciordia, Luiz Stark Aroeira, Loreto Hierro, Pablo Pérez‐Montero, David Vicent, Fernando José Corrales · 2024 · BioFactors
  81. Global Epidemiology of Cirrhosis in Women
    Gabrielle Jutras, Jennifer A. Flemming · 2024 · The American Journal of Gastroenterology
  82. Functional roles of gut bacteria imbalance in cholangiopathies
    Keisaku Sato, Fanyin Meng, Giammarco Fava, Shannon S. Glaser, Gianfranco D. Alpini · 2018 · Liver Research
  83. Therapeutic action against chronic cholestatic liver injury by low-dose fenofibrate involves anti-chemotaxis via JNK–AP1–CCL2/CXCL2 signaling
    Manyun Dai, Julin Yang, Yishuang Luo, Liping Xu, Haoyue Zhang, Gang-Ming Xu, Aiming Liu · 2020 · Pharmacological Reports
  84. Mammalian Target of Rapamycin Complex 2 Signaling Is Required for Liver Regeneration in a Cholestatic Liver Injury Murine Model
    Yi Zhou, Meng Michelle Xu, Liu Pin, Bin-yong Liang, Manning Qian, Haichuan Wang, Xinhua Song, Pranavanand Nyshadham, Li Che, Diego Francesco Calvisi et al. · 2020 · American Journal Of Pathology
  85. Pregnane X receptor as a therapeutic target for cholestatic liver injury
    Huan Lan, Ying Zhang, Minqi Fan, Bingxin Wu, Caiyan Wang · 2023 · Drug Metabolism Reviews
  86. Engineered FGF19ΔKLB protects against intrahepatic cholestatic liver injury in ANIT-induced and Mdr2-/- mice model
    Lu Shi, Tiantian Zhao, Lei Huang, Xiaomin Pan, Tianzhen Wu, Xin Feng, Taoli Chen, Jiamin Wu, Jianlou Niu · 2023 · BMC Biotechnology
  87. Carnosine Mitigates Biomarkers of Oxidative Stress, Improves Mitochondrial Function, and Alleviates Histopathological Alterations in the Renal Tissue of Cholestatic Rats
    Omid Farshad, Mohammad Mehdi Ommati, Jale Yüzügülen, Akram Jamshidzadeh, Khadijeh Mousavi, Zahra Ahmadi, Negar Azarpira, Hasti Ghaffari, Asma Najibi, Marzieh Shafaghat et al. · 2020 · Pharmaceutical Sciences
  88. Hepatoprotective effect of astaxanthin against cholestasis liver fibrosis induced by bile duct ligation in adult Wistar rats
    Azadeh Laderian, Maedeh Ghasemi, Pejman Mortazavi, Zahra Mousavi, Mahsa Ale‐Ebrahim · 2024 · Journal of Biochemical and Molecular Toxicology
  89. Autoimmunerkrankungen der Leber
    Nadine Pannicke, Christoph Schramm, Ansgar Wilhelm Lohse · 2012 · Der Internist
  90. Molecular Insights of Cholestasis in MDR2 Knockout Murine Liver Organoids
    Irene Blázquez‐García, Laura Guerrero, Cristina Cacho-Navas, Nabil Djouder, Jaime Millán, Alberto Paradela, Lorena Carmona‐Rodríguez, Fernando José Corrales · 2024 · Journal of Proteome Research
  91. A rare cause of a cholestatic jaundice in a North African teenager
    Philipp Schreiner, Bruno Stieger, Valérie A. McLin, Anne‐Laure Rougemont, Verena Keitel, Carola Dröge, Beat Müllhaupt · 2019 · Liver International
  92. Substance-P prevents the cholestatic liver injury by regulating inflammatory responses
    Suna Kim, Hyun Sook Hong · 2021 · Peptides
  93. Pharmacology of Iridoids
    Biswanath Dinda · 2019 · Springer eBooks
  94. Myocyte Enhancer Factor 2A Contributes to the TGF-β1-Mediated Cholangiocyte Epithelial to Mesenchymal Transition and Senescence in Cholestatic Liver Fibrosis
    Guangxi Zhou, Fei Hou, Heng He, Yuan Xue, Yibo Wang, Xueying Chen, Fengqin Zhu · 2022 · Frontiers in Bioscience-Landmark
  95. The Role of hsa-miR-125b-5p Interaction with S1P/Ceramide Axis in the Potential Development of Inflammation-Associated Colon Cancer in Primary Sclerosing Cholangitis
    Joanna Abramczyk, Małgorzata Milkiewicz, Bartosz Huła, Piotr Milkiewicz, Agnieszka Kempińska‐Podhorodecka · 2023 · International Journal of Molecular Sciences
  96. Therapeutic approaches for cholestatic liver diseases: the role of nitric oxide pathway
    Naser‐Aldin Lashgari, Danial Khayatan, Nazanin Momeni Roudsari, Saeideh Momtaz, Ahmad Reza Dehpour, Amir Hossein Abdolghaffari · 2023 · Naunyn-Schmiedeberg s Archives of Pharmacology
  97. Lignans are the main active components of Schisandrae Chinensis Fructus for liver disease treatment: a review
    Ke Fu, Shu Dai, Cheng Ma, Yafang Zhang, Shenglin Zhang, Cheng Wang, Lihong Gong, Honglin Zhou, Yunxia Li · 2023 · Food Science and Human Wellness
  98. Immunological diseases of the pancreatico-hepatobiliary system: update on etiopathogenesis and cross-sectional imaging findings
    Deepak Kumar Garg, Arpit M Nagar, Shaile Philips, Naoki Takahashi, Srinivasa R. Prasad, Krishna Shanbhogue, Dushyant V. Sahani · 2011 · Abdominal Imaging
  99. Ursodeoxycholic Acid Influences the Expression of p27kip1 but Not FoxO1 in Patients with Non-Cirrhotic Primary Biliary Cirrhosis
    Małgorzata Milkiewicz, Justyna Kopycińska, Agnieszka Kempińska‐Podhorodecka, Tara L. Haas, Dimitrios Petrou Bogdanos, Elwyn Elias, Piotr Milkiewicz · 2014 · Journal of Immunology Research
  100. Gentamicin alleviates cholestatic liver injury by decreasing gut microbiota-associated bile salt hydrolase activity in rats
    Yanrong Ma, Huan Wang, Jinru Yang, Mingyan Xin, Xinan Wu · 2023 · European Journal of Pharmacology