The DOI matches its Crossref record; 167 of the 167 references it cites were found in a registry or an index.
Genetics, Cell Biology, and Pathophysiology of Pancreatitis
Open accessAbstract
Since the discovery of the first trypsinogen mutation in families with hereditary pancreatitis, the field of pancreatic genetics has made rapid progress. The identification of mutations in genes involved in the digestive protease/antiprotease pathway has lent additional support to the notion that pancreatitis is a disease of autodigestion. Clinical and experimental observations provided compelling evidence that premature, intrapancreatic activation of digestive proteases is critical in pancreatitis onset. Disease course and severity, however, are mostly governed by inflammatory cells that drive local and systemic immune responses. Here we review the genetics, cell biology and immunology of pancreatitis with a focus on protease activation pathways and other early events.
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Cites
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Cited by
Diagnosis and Management of Chronic Pancreatitis: A Review
Singh, V. K., Yadav, D., & Garg, P. K. (2019) · JAMA · doi:10.1001/jama.2019.19411 · Cited by 486
Liu, L., Xie, Y., Li, G., Zhang, T., Sui, Y., Zhao, Z., Zhang, Y., Yang, W., Geng, X., Xue, D., et al. (2023) · British Journal of Pharmacology · doi:10.1111/bph.15980 · Cited by 56
Mechanotransductive receptor Piezo1 as a promising target in the treatment of fibrosis diseases
Xu, Y., Huang, Y., Cheng, X., Hu, B., Jiang, D., Wu, L., Peng, S., & Hu, J. (2023) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2023.1270979 · Cited by 24
Lowe, M. E., Andersen, D. K., Caprioli, R. M., Choudhary, J., Cruz-Monserrate, Z., Dasyam, A. K., Forsmark, C. E., Gorelick, F. S., Gray, J. W., Haupt, M., et al. (2019) · Pancreas · doi:10.1097/mpa.0000000000001412 · Cited by 15
Metadata
- Authors
- Mayerle, J., Sendler, M., Hegyi, E., Beyer, G., Lerch, M. M., & Sahin-Tóth, M.
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2019-05
- Volume
- 156
- Issue
- 7
- Pages
- 1951-1968.e1
- ISSN
- 0016-5085 (ISSN-L)
- OpenAlex
- W2910053234
- Cited by
- 375
- References
- 167
- FWCI
- 29.38
- Type
- journal article
- Language
- en
- Open access
- green
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- Mayerle, J., Sendler, M., Hegyi, E., Beyer, G., Lerch, M. M., & Sahin-Tóth, M. (2019). Genetics, Cell Biology, and Pathophysiology of Pancreatitis. Gastroenterology. https://doi.org/10.1053/j.gastro.2018.11.081
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
