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The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Identification of Reduced ERAP2 Expression and a Novel HLA Allele as Components of a Risk Score for Susceptibility to Liver Injury Due to Amoxicillin-Clavulanate

Nicoletti, Paola, Dellinger, Andrew, Li, Yi Ju, Barnhart, Huiman X., Chalasani, Naga, Fontana, Robert J., Odin, Joseph A., Serrano, Jose, Stolz, Andrew, Etheridge, Amy S., Innocenti, Federico, Govaere, Olivier, Grove, Jane I., Stephens, Camilla, Aithal, Guruprasad P., Andrade, Raul J., Bjornsson, Einar S., Daly, Ann K., Lucena, M. Isabel, Watkins, Paul B.·2023·Gastroenterology
DOI 10.1053/j.gastro.2022.11.036PMC PMC9974860
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  • International DILI consortia have contributed to construction of a polygenic risk score for amoxicillin-clavulanate susceptibility, which may also improve causality assessment.

    “In addition, the international DILI consortia have contributed to the construction of a polygenic risk score for amoxicillin‐clavulanate susceptibility, which may also improve causality assessment.”

    From Methods for causality assessment of idiosyncratic drug‐induced liver injury (2025) · cites this paper as [65]

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Research works printed but not linked: 32

  1. Chalasani, 2015, Features and outcomes of 899 patients with drug-induced liver injury: the DILIN prospective study, Gastroenterology, 148, 1340, 10.1053/j.gastro.2015.03.006 · DOI · Paper page
  2. Watkins, 2019, Idiosyncratic drug-induced liver injury in patients: detection, severity assessment, and regulatory implications, Adv Pharmacol, 85, 165, 10.1016/bs.apha.2019.02.004 · DOI
  3. deLemos, 2016, Amoxicillin-clavulanate-induced liver injury, Dig Dis Sci, 61, 2406, 10.1007/s10620-016-4121-6 · DOI
  4. Lucena, 2006, Determinants of the clinical expression of amoxicillin-clavulanate hepatotoxicity: a prospective series from Spain, Hepatology, 44, 850, 10.1002/hep.21324 · DOI
  5. Lucena, 2011, Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles, Gastroenterology, 141, 338, 10.1053/j.gastro.2011.04.001 · DOI · Paper page
  6. Stephens, 2013, HLA alleles influence the clinical signature of amoxicillin-clavulanate hepatotoxicity, PLoS One, 8, 10.1371/journal.pone.0068111 · DOI
  7. Cirulli, 2019, A missense variant in PTPN22 is a risk factor for drug-induced liver injury, Gastroenterology, 156, 1707, 10.1053/j.gastro.2019.01.034 · DOI · Paper page
  8. Stanford, 2014, PTPN22: the archetypal non-HLA autoimmunity gene, Nat Rev Rheumatol, 10, 602, 10.1038/nrrheum.2014.109 · DOI
  9. de Castro, 2019, Intracellular antigen processing by ERAP2: molecular mechanism and roles in health and disease, Hum Immunol, 80, 310, 10.1016/j.humimm.2018.11.001 · DOI
  10. Fontana, 2009, Drug-Induced Liver Injury Network (DILIN) prospective study: rationale, design and conduct, Drug Saf, 32, 55, 10.2165/00002018-200932010-00005 · DOI · Paper page
  11. Aithal, 2011, Case definition and phenotype standardization in drug-induced liver injury, Clin Pharmacol Ther, 89, 806, 10.1038/clpt.2011.58 · DOI · Paper page
  12. Nicoletti, 2017, Association of liver injury from specific drugs, or groups of drugs, with polymorphisms in HLA and other genes in a genome-wide association study, Gastroenterology, 152, 1078, 10.1053/j.gastro.2016.12.016 · DOI · Paper page
  13. Gamazon, 2015, A gene-based association method for mapping traits using reference transcriptome data, Nat Genet, 47, 1091, 10.1038/ng.3367 · DOI
  14. Das, 2016, Next-generation genotype imputation service and methods, Nat Genet, 48, 1284, 10.1038/ng.3656 · DOI · Paper page
  15. Zheng, 2014, HIBAG–HLA genotype imputation with attribute bagging, Pharmacogenomics J, 14, 192, 10.1038/tpj.2013.18 · DOI
  16. Purcell, 2007, PLINK: a tool set for whole-genome association and population-based linkage analyses, Am J Hum Genet, 81, 559, 10.1086/519795 · DOI · Paper page
  17. Ombrello, 2015, Endoplasmic reticulum-associated amino-peptidase 1 and rheumatic disease: genetics, Curr Opin Rheumatol, 27, 349, 10.1097/BOR.0000000000000189 · DOI
  18. Cordell, 2009, Detecting gene-gene interactions that underlie human diseases, Nat Rev Genet, 10, 392, 10.1038/nrg2579 · DOI · Paper page
  19. Youden, 1950, Index for rating diagnostic tests, Cancer, 3, 32, 10.1002/1097-0142(1950)3:1<32::AID-CNCR2820030106>3.0.CO;2-3 · DOI
  20. Andres, 2010, Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation, PLoS Genet, 6, 10.1371/journal.pgen.1001157 · DOI
  21. Etheridge, 2020, A new liver expression quantitative trait locus map from 1,183 individuals provides evidence for novel expression quantitative trait loci of drug response, metabolic, and sex-biased phenotypes, Clin Pharmacol Ther, 107, 1383, 10.1002/cpt.1751 · DOI
  22. Nicoletti, 2019, Drug-induced liver injury due to flucloxacillin: relevance of multiple human leukocyte antigen alleles, Clin Pharmacol Ther, 106, 245, 10.1002/cpt.1375 · DOI
  23. Zumelzu, 2011, Black patients of African descent and HLA-DRB1∗15:03 frequency overrepresented in epidermolysis bullosa acquisita, J Invest Dermatol, 131, 2386, 10.1038/jid.2011.231 · DOI
  24. Robinson, 2012, The genetics of ankylosing spondylitis and axial spondyloarthritis, Rheum Dis Clin North Am, 38, 539, 10.1016/j.rdc.2012.08.018 · DOI
  25. Kuiper, 2018, Functionally distinct ERAP1 and ERAP2 are a hallmark of HLA-A29-(Birdshot) Uveitis, Hum Mol Genet, 27, 4333
  26. Tailor, 2020, HLA DRB1∗15:01-DQB1∗06:02-restricted human CD4+ T cells are selectively activated with amoxicillin-peptide adducts, Toxicol Sci, 178, 115, 10.1093/toxsci/kfaa128 · DOI
  27. Alvarez-Navarro, 2014, ERAP1 structure, function and pathogenetic role in ankylosing spondylitis and other MHC-associated diseases, Mol Immunol, 57, 12, 10.1016/j.molimm.2013.06.012 · DOI
  28. Overby, 2014, Estimating heritability of drug-induced liver injury from common variants and implications for future study designs, Sci Rep, 4, 5762, 10.1038/srep05762 · DOI
  29. O'Connor, 2021, The distribution of common-variant effect sizes, Nat Genet, 53, 1243, 10.1038/s41588-021-00901-3 · DOI · Paper page
  30. Chalasani, 2017, Idiosyncratic drug induced liver injury in African-Americans is associated with greater morbidity and mortality compared to Caucasians, Am J Gastroenterol, 112, 1382, 10.1038/ajg.2017.215 · DOI · Paper page
  31. Hollenbach JA, Ombrello MJ, Tremoulet AH, et al. IL-1 and IL-6 inhibitor hypersensitivity link to common HLA-DRB1∗15 alleles. medRxiv Preprint posted online January 17, 2021. https://doi.org/10.1101/2020.08.10.20172338 · DOI
  32. Kaliyaperumal, 2018, Pharmacogenomics of drug-induced liver injury (DILI): molecular biology to clinical applications, J Hepatol, 69, 948, 10.1016/j.jhep.2018.05.013 · DOI

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Metadata

Authors
Nicoletti, P., Dellinger, A., Li, Y. J., Barnhart, H. X., Chalasani, N., Fontana, R. J., Odin, J. A., Serrano, J., Stolz, A., Etheridge, A. S., Innocenti, F., Govaere, O., Grove, J. I., Stephens, C., Aithal, G. P., Andrade, R. J., Bjornsson, E. S., Daly, A. K., Lucena, M. I., & Watkins, P. B.
Venue
Gastroenterology
Publisher
Elsevier BV
Published
2023-03
Volume
164
Issue
3
Pages
454-466
ISSN
0016-5085
DOI
10.1053/j.gastro.2022.11.036
PMC
PMC9974860
Cited by
50
References
4
Language
en
Licence
Funders
  • NIDDKD (U01-DK065201, U01-DK083023, U01-DK065211, U01-DK082992, U01-DK065184, U01DK065193, U01-DK065176)
  • Johns Hopkins University (UOIHG004599, U01HG004424)
  • Instituto de Salud Carlos III
  • University of Nottingham
  • Duke University (U01-DK065201)
  • Indiana University (U01DK065193)
  • National Institutes of Health (R01 MH084098, RC2MH089964, U01HG007417)
  • University of North Carolina Wilmington (U01-DK065184)
  • European Cooperation in Science and Technology (BRC-1215-20003, CA17112)
  • National Human Genome Research Institute (U01HG004438, U01AG006781)
  • National Eye Institute
  • Vanderbilt University
  • NCATS
  • University of Connecticut
  • European Regional Development Fund (FIS PI16_01748, PI15 _01440)
  • Broad Institute (RC2MH089964, R01 MH084098, U01HG007417, U01HG004608, U01HG04603, U01HG004603)
  • National Cancer Institute (U01CA155309)
  • Hebrew University of Jerusalem
  • Icahn School of Medicine at Mount Sinai
  • Mayo Clinic
  • University of Texas Southwestern Medical Center
  • University of Southern California
  • National Institute for Health and Care Research
  • University of Michigan (U01-DK065211)
  • Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
  • Spanish Agency for Medications and Health Products

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