Regenerative peripheral nerve interface for prostheses control: electrode comparison
Abstract
BACKGROUND: This study compared epimysial patch electrodes with intramuscular hook electrodes using monopolar and bipolar recording configurations. The purpose was to determine which strategy transduced muscle signals with better fidelity for control of myoelectric prostheses. METHODS: One of the two electrode styles, patch (n = 4) or hook (n = 6) was applied to the left extensor digitorum longus muscle in rats. Electrodes were evaluated at the time of placement and at monthly intervals for 4 months. Evaluations consisted of evoked electromyography signals from stimulation pulses applied to the peroneal and tibial nerves in both monopolar and bipolar recording configurations. RESULTS: Compared with hook electrodes, patch electrodes recorded larger signals of interest and minimized muscle tissue injury. A bipolar electrode configuration significantly reduced signal noise when compared with a monopolar configuration. CONCLUSION: Epimysial patch electrodes outperform intramuscular hook electrodes during chronic skeletal muscle implantation.
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Increasing growth rate of regeneration of individual or groups of fibers through holes in RPNI can activate selective stimulation and make it possible to record action potentials from individual axons or a small group.
“The increase in growth rate of regeneration of individual or a group of fibers through those holes can activate selective stimulation and make it possible to record action potentials (Micera and Navarro, 2009; Sando et al., 2016) from individual axons or a small group.”
From Selectivity and Longevity of Peripheral-Nerve and Machine Interfaces: A Review. (2017) · cites this paper as Sando et al., 2016
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“The increase in growth rate of regeneration of individual or a group of fibers through those holes can activate selective stimulation and make it possible to record action potentials (Micera and Navarro, 2009; Sando et al., 2016) from individual axons or a small group.”
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<i>In vivo</i> characterization of regenerative peripheral nerve interface function
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Self-citationRegenerative Peripheral Nerve Interface Surgery: Anatomic and Technical Guide
Leach, G. A., Dean, R. A., Kumar, N. G., Tsai, C., Chiarappa, F. E., Cederna, P. S., Kung, T. A., & Reid, C. M. (2023) · Plastic & Reconstructive Surgery Global Open · doi:10.1097/gox.0000000000005127 · Cited by 41 · see citing works
Self-citationWang, Z., Yi, X. Z., & Yi, X. Z. (2022) · Neural Regeneration Research · doi:10.4103/1673-5374.353498 · Cited by 26 · see citing works
“An RPNI is constructed by implanting a PNS into a free skeletal muscle graft and was originally designed to transduce and amplify neural signals for controlling a neuroprosthetic limb (Kung et al., 2014; Sando et al., 2016; Frost et al., 2018; Vu et al., 2020).”
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BackgroundMethodResultInfluentialUpdate on Upper Limb Neuroma Management
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Ursu, D. C. (2016) · Deep Blue (University of Michigan)
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- Authors
- Sando, I., Leach, M., Woo, S., Moon, J., Cederna, P., Langhals, N., & Urbanchek, M.
- Affiliations
- University of Michigan (US)
- Venue
- Journal of Reconstructive Microsurgery
- Publisher
- Georg Thieme Verlag KG
- Published
- 2015-10-26
- Volume
- 32
- Issue
- 03
- Pages
- 194-199
- ISSN
- 0743-684X (ISSN-L)
- 1098-8947
- OpenAlex
- W2258501430
- Cited by
- 14
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 1 · 2021: 1 · 2018: 1 · 2017: 2 · 2016: 4
- FWCI
- 1.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Reconstructive Microsurgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Physical Sciences › Engineering › Biomedical Engineering › Muscle activation and electromyography studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › EEG and Brain-Computer Interfaces
- Keywords
- peripheral nerve interfaces, myoelectric prosthesis, bipolar recording, extensor digitorum longus, evoked electromyography, signal noise, neurostimulation
- MeSH terms
- Animals, Electric Stimulation, Electrodes, Electromyography, Hindlimb, Nerve Regeneration, Peripheral Nerves, Rats, Inbred F344, Muscle, Skeletal, Rats
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