Low Anterior Resection Syndrome: Current Management and Future Directions
Open accessAbstract
Outcomes for rectal cancer surgery have improved significantly over the past 20 years with increasing rates of survival and recurrence, specifically local recurrence. These gains have been realized during a period of time in which there has been an increasing emphasis on sphincter preservation. As we have become increasingly aggressive in avoiding resection of the anus, we have begun accepting bowel dysfunction as a normal outcome. Low anterior resection syndrome, defined as a constellation of symptoms including incontinence, frequency, urgency, or feelings of incomplete emptying, has a significant impact on quality of life and results in many patients opting for a permanent colostomy to avoid these symptoms. In this article, we will highlight the most recent clinical and basic science research on this topic and discuss areas of future investigation.
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LARS and GIQLI are commonly accepted tools for the evaluation of postoperative bowel dysfunction in patients undergoing a low anterior resection.
“LARS and GIQLI are commonly accepted tools for the evaluation of postoperative bowel dysfunction in patients undergoing a low anterior resection.”
From Pain, gastrointestinal function and fertility outcomes of modified nerve‐vessel sparing segmental and full thickness discoid resection for deep colorectal endometriosis – A prospective cohort study (2023) · cites this paper as [20]
The Abstract reports use of a LAR syndrome score to assess symptoms after low anterior resection, and the Discussion (p. 241) recommends standardized questionnaires for bowel function and quality of life. Our copy does not identify GIQLI or establish that LARS and GIQLI are both commonly accepted tools. (LLM, conf=0.82)
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- Authors
- Berger, N., Ludwig, K., & Ridolfi, T.
- Affiliations
- Medical College of Wisconsin (US)
- Corresponding author
- Ridolfi, Timothy
- Venue
- Clinics in Colon and Rectal Surgery
- Publisher
- Georg Thieme Verlag KG
- Published
- 2016-08-19
- Volume
- 29
- Issue
- 03
- Pages
- 239-245
- ISSN
- 1521-5741 (ISSN-L)
- 1531-0043
- 1530-9681
- PMC
- PMC4991969
- OpenAlex
- W2512979748
- Cited by
- 88
- References
- 59
- Citations by year
- 2026: 10 · 2025: 9 · 2024: 8 · 2023: 11 · 2022: 11 · 2021: 13 · 2020: 11 · 2019: 8 · 2018: 5 · 2017: 2
- FWCI
- 0.50
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinics in Colon and Rectal Surgery (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Colorectal Cancer Surgical Treatments
- Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
- Health Sciences › Medicine › Surgery › Colorectal and Anal Carcinomas
- Keywords
- low anterior resection syndrome, rectal cancer surgery, sphincter preservation, fecal incontinence, bowel dysfunction, quality of life, permanent colostomy, local recurrence, anorectal function
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