Cited by 40

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Hepatic Damage by Natural Remedies

Medina-Caliz, Inmaculada, Gonzalez-Jimenez, Andres, Garcia-Cortes, Miren, Lucena, M. Isabel, Andrade, Raul·2018·Seminars in Liver Disease

Abstract

The rising burden of herbal and dietary supplement hepatotoxicity (HILI) is a growing concern in Western countries. The estimated incidence of HILI in well-designed prospective studies ranges from less than 1 to 3 individuals per 100,000 inhabitants/year. Herbal hepatotoxicity has a particular signature encompassing female predominance, hepatocellular type of damage with markedly elevated transaminases on presentation, more common unintentional rechallenge, and a greater risk of death/liver transplantation. Herbal hepatotoxicity recognition is particularly challenging for hepatologists because of the often hidden herbal consumption, difficulties in identifying the causative herbal component, and the possibility of contamination, adulteration, and misidentification, which preclude a proper adjudication and lead to inaccurate reporting of cases in scientific journals. Collaborative efforts to retrieve detailed phenotypic data and biological samples of patients with HILI would facilitate genomic and other molecular approaches for a better understanding of host risk factors and, hopefully, for biomarker identification.

Overview

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Registry

Crossref · 10.1055/s-0038-1623518

Cites

7 of 7 references verified0 citation errors · 0 not checkable

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Verification

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Claims other papers make about this one

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  • The proportion of DILI cases attributed to medicinal plants and dietary supplements is increasing worldwide.

    “The proportion of DILI cases attributed to medicinal plants and dietary supplements is increasing worldwide, indicating an evolving trend in the epidemiology of DILI and pointing to the need for greater awareness and regulation [7,8].”

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Metadata

Authors
Medina-Caliz, I., Gonzalez-Jimenez, A., Garcia-Cortes, M., Lucena, M. I., & Andrade, R.
Venue
Seminars in Liver Disease
Published
2018-02
Volume
38
Issue
01
Pages
021-040
ISSN
  • 0272-8087
  • 1098-8971
Cited by
40
References
7
Language
en

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