The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Nucleus Accumbens Deep Brain Stimulation for Alcohol Addiction – Safety and Clinical Long-term Results of a Pilot Trial
Open accessAbstract
We report on the long-term clinical outcome (up to 8 years) of 5 patients who received deep brain stimulation (DBS) of the nucleus accumbens to treat their long-lasting and treatment-resistant alcohol addiction. All patients reported a complete absence of craving for alcohol; 2 patients remained abstinent for many years and 3 patients showed a marked reduction of alcohol consumption. No severe or long-standing side effects occurred. Therefore, DBS could be a promising, novel treatment option for severe alcohol addiction, but larger clinical trials are needed to further investigate the efficacy of DBS in addiction.
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“In a study of five participants with treatment-resistant alcohol use disorder who received DBS of the NAc, all reported a complete absence of craving for alcohol up to 8 years following DBS implantation; two patients remained abstinent for several years, and three showed a marked reduction of alcohol consumption [90].”
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Neural systems of reinforcement for drug addiction: from actions to habits to compulsion
Everitt, B. J., & Robbins, T. W. (2005) · Nature Neuroscience · doi:10.1038/nn1579 · Cited by 3,785
A cognitive model of drug urges and drug-use behavior: role of automatic and nonautomatic processes
Tiffany, S. T. (1990) · Psychological Review · doi:10.1037/0033-295x.97.2.147 · Cited by 1,554
The Development and Maintenance of Drug Addiction
Wise, R. A., & Koob, G. F. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.261 · Cited by 617
The clinical significance of drug craving
Tiffany, S. T., & Wray, J. M. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06298.x · Cited by 556
Jasinska, A. J., Stein, E. A., Kaiser, J., Naumer, M. J., & Yalachkov, Y. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.10.013 · Cited by 513
Maisel, N. C., Blodgett, J. C., Wilbourne, P. L., Humphreys, K., & Finney, J. W. (2013) · Addiction · doi:10.1111/j.1360-0443.2012.04054.x · Cited by 470
The dark side of emotion: the addiction perspective
Koob, G. F. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2014.11.044 · Cited by 433
Human alcohol-related neuropathology
de la Monte, S. M., & Kril, J. J. (2014) · Acta Neuropathologica · doi:10.1007/s00401-013-1233-3 · Cited by 416
Alcohol use disorders and mortality: a systematic review and meta-analysis
Roerecke, M., & Rehm, J. (2013) · Addiction · doi:10.1111/add.12231 · Cited by 326
Alcohol and the Human Brain: A Systematic Review of Different Neuroimaging Methods
Bühler, M., & Mann, K. (2011) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2011.01540.x · Cited by 310
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Goutaudier, R. (2022) · theses.fr (ABES) · doi:10.70675/6619b466z54bfz41e3z8a90zf0967825d579
Samadi, F., Seddighfar, M., & Haghparast, A. (2026) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2026.111842
Levin-Carrion, Y., Riestra, J. M., Campbell, T., Titkov, K., Gibson, N., Riestra, D. B., Alabed, S. T., Meda, S., Raghu, A. L. B., Gad, S. N., et al. (2026) · Acta Neurochirurgica · doi:10.1007/s00701-026-06979-0
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Metadata
- Authors
- Müller, U., Sturm, V., Voges, J., Heinze, H.-J., Galazky, I., Büntjen, L., Heldmann, M., Frodl, T., Steiner, J., & Bogerts, B.
- Affiliations
- Otto-von-Guericke-Universität Magdeburg (DE)
- University of Cologne (DE)
- Department of Stereotactic Neurosurgery, Otto-von-Guericke-University of Magdeburg, Magdeburg
- Corresponding author
- Müller, U.
- Venue
- Pharmacopsychiatry
- Publisher
- Georg Thieme Verlag KG
- Published
- 2016-05-04
- Volume
- 49
- Issue
- 04
- Pages
- 170-173
- ISSN
- 0176-3679 (ISSN-L)
- 1439-0795
- OpenAlex
- W2346795379
- Cited by
- 108
- References
- 26
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 12 · 2023: 10 · 2022: 14 · 2021: 10 · 2020: 13 · 2019: 7 · 2018: 20 · 2017: 4 · 2016: 2
- FWCI
- 8.26
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Pharmacopsychiatry (publishedVersion)
- PubMed (publishedVersion)
- Kölner Universitäts PublikationsServer (Universität zu Köln) (publishedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- deep brain stimulation, nucleus accumbens, alcoholism, alcohol craving, alcohol abstinence, long-term outcomes
- MeSH terms
- Adult, Alcoholism, Humans, Longitudinal Studies, Middle Aged, Nucleus Accumbens, Pilot Projects, Psychiatric Status Rating Scales, Surveys and Questionnaires, Deep Brain Stimulation
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