Obesity and Cardiovascular Disease: Pathogenic Mechanisms and Potential Benefits of Weight Reduction
Abstract
The prevalence of obesity in industrialized countries has reached epidemic proportions, with about one in three people being obese and another one in three people being overweight and at risk of developing obesity. In recent years, obesity has gained the traditional tetrad of cardiovascular risk factors of smoking: hypertension, dyslipidemia, and dysglycemia. Attention has also focused on the importance of abdominal (or central) obesity as a determinant of cardiovascular risk, independent of the body mass index. In addition to effects on coronary artery disease, obesity has an effect on cardiovascular disease, including stroke, ventricular function, peripheral arterial disease, and venous thromboembolism. The objectives of this review are to summarize the effects of obesity on cardiovascular disease, and the possible mechanisms for these associations, and to investigate the effects of weight-loss interventions on the burden of cardiovascular disease. Large ongoing clinical outcome trials, such as the SOS study, the Look-AHEAD trial, or the SCOUT study, should provide important information on the effects of surgical and nonsurgical obesity treatment on cardiovascular morbidity and mortality.
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Obesity is strongly associated with the development of major risk factors for atherosclerotic disease such as hypertension, hyperlipidemia, and diabetes.
“Obesity is strongly associated with the development of major risk factors for atherosclerotic disease such as hypertension, hyperlipidemia, and diabetes (79, 89, 358).”
From Cardiac remodeling in obesity (2008) · cites this paper as [89]
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Abel, E. D., Litwin, S. E., & Sweeney, G. (2008) · Physiological Reviews · doi:10.1152/physrev.00017.2007 · Cited by 736 · see citing works
“Obesity is strongly associated with the development of major risk factors for atherosclerotic disease such as hypertension, hyperlipidemia, and diabetes (79, 89, 358).”
BackgroundDarvall, K., Sam, R. C., Silverman, S., Bradbury, A. W., & Adam, D. J. (2006) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2006.10.006 · Cited by 337 · see citing works
Katcher, H. I., Legro, R. S., Kunselman, A. R., Gillies, P. J., Demers, L. M., Bagshaw, D. M., & Kris-Etherton, P. M. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.1.79 · Cited by 317 · see citing works
“However, there were improvements in many of these variables with weight loss, which is in agreement with the findings of other studies (43, 44).”
ResultChen, B., Lam, K. S. L., Wang, Y., Wu, D., Lam, M. C., Shen, J., Wong, L., Hoo, R. L. C., Zhang, J., & Xu, A. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.01.004 · Cited by 238 · see citing works
Ryan, D. H. (2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2009.508 · Cited by 143 · see citing works
Blood pressure as a prognostic factor after acute stroke
Tikhonoff, V., Zhang, H., Richart, T., & Staessen, J. A. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70184-x · Cited by 122 · see citing works
Canonico, M., Oger, E., Conard, J., Meyer, G., Levesque, H., Trillot, N., Barrellier, M. ‐., Wahl, D. G., Emmerich, J., & Scarabin, P. (2006) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2006.01933.x · Cited by 115 · see citing works
Blood Pressure Lowering for Primary and Secondary Prevention of Stroke
Zhang, H., Thijs, L., & Staessen, J. A. (2006) · Hypertension · doi:10.1161/01.hyp.0000231939.40959.60 · Cited by 117 · see citing works
Risk of ischemic stroke and lifetime estrogen exposure
de Leciñana, M. A., Egido, J. A., Fernández, C., Martínez‐Vila, E., Santos, S. S., Morales, A., Martínez, E., Pareja, A., Álvarez‐Sabín, J., & Casado, I. (2007) · Neurology · doi:10.1212/01.wnl.0000250238.69938.f5 · Cited by 116 · see citing works
Cardiovascular Risk-Benefit Profile of Sibutramine
Scheen, A. J. (2010) · American Journal of Cardiovascular Drugs · doi:10.2165/11584800-000000000-00000 · Cited by 89 · see citing works
Resveratrol inhibits TNF-α-induced changes of adipokines in 3T3-L1 adipocytes
Ahn, J., Lee, H., Kim, S., & Ha, T. Y. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.10.109 · Cited by 89 · see citing works
Influence of body mass index on prognosis in gynecological malignancies
Münstedt, K., Wagner, M., Kullmer, U., Hackethal, A., & Franke, F. E. (2008) · Cancer Causes & Control · doi:10.1007/s10552-008-9152-7 · Cited by 86 · see citing works
“Overweight has long been recognized as a risk factor for diabetes and cardiovascular diseases [3].”
BackgroundLife Course Models of Socioeconomic Position and Cardiovascular Risk Factors: 1946 Birth Cohort
Murray, E. T., Mishra, G. D., Kuh, D. J., Guralnik, J. M., Black, S., & Hardy, R. (2011) · Annals of Epidemiology · doi:10.1016/j.annepidem.2011.04.005 · Cited by 84 · see citing works
“Seven additional CVD risk factors were chosen which have been shown to be related to SEP assessed at any period in the life course [3] and BMI [14, 15]: triglycerides (TRIG), glycated haemoglobin (HbA1c), systolic and diastolic blood pressure (SBP/DBP), total cholesterol (CHOL), and low-density and high-density lipopr…”
BackgroundConsequences of obesity and weight loss: a devil's advocate position
Brown, R. E., & Kuk, J. L. (2014) · Obesity Reviews · doi:10.1111/obr.12232 · Cited by 79 · see citing works
“sion, myocardial infarction, coronary artery disease, stroke and heart failure (9).”
BackgroundBMI Versus the Metabolic Syndrome in Relation to Cardiovascular Risk in Elderly Chinese Individuals
He, Y., Jiang, B., Wang, J., Feng, K., Chang, Q., Zhu, S., Fan, L., Li, X., & Hu, F. B. (2007) · Diabetes Care · doi:10.2337/dc06-2402 · Cited by 69 · see citing works
Links between thermoregulation and aging in endotherms and ectotherms
Flouris, A. D., & Piantoni, C. (2014) · Temperature · doi:10.4161/23328940.2014.989793 · Cited by 62 · see citing works
Weight reduction for primary prevention of stroke in adults with overweight or obesity
Curioni, C. C., André, C., & Veras, R. P. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006062.pub2 · Cited by 59 · see citing works
Sibutramine on Cardiovascular Outcome
Scheen, A. J. (2011) · Diabetes Care · doi:10.2337/dc11-s205 · Cited by 55 · see citing works
“Weight loss is considered to be the initial step that helps to prevent or to control the clinical consequences of obesity (5,6), especially in patients with type 2 diabetes (7).”
BackgroundInfluentialThe role of self-monitoring in the maintenance of weight loss success
Laitner, M. H., Minski, S. A., & Perri, M. G. (2016) · Eating Behaviors · doi:10.1016/j.eatbeh.2016.03.005 · Cited by 49 · see citing works
Environmental vascular risk factors: New perspectives for stroke prevention
Bernal-Pacheco, Ó., & Román, G. C. (2007) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2007.06.026 · Cited by 48 · see citing works
Metabolic Syndrome: Development of the Issue, Main Diagnostic Criteria
Belenkov, Y. N., Privalova, E. V., Kaplunova, V. Y., Zektser, V., Виноградова, Н. Н., Ilgisonis, I. S., Андрониковна, Ш. Г., Kozhevnikova, M. V., & Лишута, А. С. (2018) · Rational Pharmacotherapy in Cardiology · doi:10.20996/1819-6446-2018-14-5-757-764 · Cited by 46 · see citing works
Obesity Reduction Black Intervention Trial (ORBIT): Design and Baseline Characteristics
Fitzgibbon, M., Stolley, M. R., Schiffer, L. A., Sharp, L. K., Singh, V., Horn, L. V., & Dyer, A. R. (2008) · Journal of Women s Health · doi:10.1089/jwh.2007.0614 · Cited by 42 · see citing works
Dedov, I. I., Melnichenko, G. A., Troshina, E. A., Mazurina, N. V., & Galieva, M. O. (2018) · Obesity Facts · doi:10.1159/000488880 · Cited by 37 · see citing works
Clinical efficacy and safety of angiogenesis inhibitors: sex differences and current challenges
Cignarella, A., Fadini, G. P., Bolego, C., Trevisi, L., Boscaro, C., Sanga, V., Seccia, T. M., Rosato, A., Rossi, G. P., & Barton, M. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab096 · Cited by 36 · see citing works
Chan, A., Lam, K. F., TONG, T., et al. (2006) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.02958.x · Cited by 32 · see citing works
Yang, Z., Wang, H., Liu, N., Zhao, K., Sheng, Y., Pang, H., Shao, K., Zhang, M., Li, S., & He, N. (2022) · Food & Function · doi:10.1039/d2fo02185d · Cited by 31 · see citing works
Goyenechea, E., Crujeiras, A. B., Abete, I., et al. (2008) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2008.08.011 · Cited by 30 · see citing works
Kim, T. K., & Park, K. S. (2015) · Cytokine · doi:10.1016/j.cyto.2015.05.015 · Cited by 29 · see citing works
“Obesity, which is characterized by excessive accumulation of abdominal fat, is casually associated with the premature development of atherosclerosis, increased risk of stroke, and development of congestive heart failure [9].”
BackgroundAshrani, A. A., Silverstein, M. D., Lahr, B. D., et al. (2009) · Vascular Medicine · doi:10.1177/1358863x09104222 · Cited by 28 · see citing works
Spies, C., Farzaneh‐Far, R., Na, B., Kanaya, A. M., Schiller, N. B., & Whooley, M. A. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.05.027 · Cited by 28 · see citing works
Incremental weight loss improves cardiometabolic risk in extremely obese adults
Johnson, W. D., Brashear, M. M., Gupta, A. K., Rood, J. C., & Ryan, D. H. (2011) · The American Journal of Medicine · doi:10.1016/j.amjmed.2011.04.033 · Cited by 26 · see citing works
Jakovljević, B. D., Stojanov, V., Lović, D. B., Paunović, K., Radosavljević, V., & Tutić, I. (2010) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2010.07.019 · Cited by 26 · see citing works
“Obesity is an important risk factor for the development of cardiovascular diseases [9,10] and peripheral arterial disease [11–14].”
BackgroundHoffmann, I., Alfieri, A. B., & Cubeddu, L. X. (2008) · Journal of Clinical Hypertension · doi:10.1111/j.1751-7176.2008.07609.x · Cited by 24 · see citing works
National trends in the use and costs of anti-obesity medications in England 1998–2005
Srishanmuganathan, J., Patel, H., Car, J., & Majeed, A. (2007) · Journal of Public Health · doi:10.1093/pubmed/fdm013 · Cited by 20 · see citing works
Overweight and Increased Cardiovascular Mortality
Hu, F. B. (2005) · Hypertension · doi:10.1161/01.hyp.0000184229.64767.a1 · Cited by 19 · see citing works
Abrams, P. J., Boquete, H., Fideleff, H. L., Feldt‐Rasmussen, U., Jönsson, P., Kołtowska‐Häggström, M., Wilton, P., & Abs, R. (2008) · European Journal of Endocrinology · doi:10.1530/eje-08-0448 · Cited by 18 · see citing works
“Reduction in body fat in overweight and obese subjects without GHD improves lipid profile (20, 21 ) and QoL (22) per se. A correlation between reduction in cholesterol and decrease in fat mass (FM) during GH treatment has similarly been proposed (23, 24).”
BackgroundCommentary: Obesity-years--a new metric to measure health effects of obesity
de Koning, L., & Hu, F. B. (2011) · International Journal of Epidemiology · doi:10.1093/ije/dyr053 · Cited by 18 · see citing works
Zhou, Z., Parra-Soto, S. L., Boonpor, J., Petermann-Rocha, F. E., Welsh, P. I., Mark, P. B., Sattar, N. A., Pell, J. P., Celis-Morales, C. A., & Ho, F. K. W. (2023) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2023.101715 · Cited by 17 · see citing works
Obesity dilemma in the global burden of cardiovascular diseases
Boban, M., Peršić, V., Jovanović, Ž., Brozina, A., Miletić, B., Rotim, A., Drinković, N., Manola, Š., Laškarin, G., & Boban, L. (2013) · International Journal of Clinical Practice · doi:10.1111/ijcp.12254 · Cited by 15 · see citing works
Actuarially speaking: an overview of life expectancy. What can we anticipate?
Blacklow, R. S. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.5.1560s · Cited by 14 · see citing works
“There is no doubt that obesity, particularly central obesity, greatly increases the onset and progression of cardiovascular disease (11).”
BackgroundPharmacotherapy for weight loss: the cardiovascular effects of the old and new agents
Walter, C. P., Bleske, B. E., & Dorsch, M. P. (2014) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1111/jcpt.12177 · Cited by 14 · see citing works
“Obesity has been associated with coronary artery disease, stroke, peripheral arterial disease, venous thromboembolism, heart failure and hypertension.(3,4) In 1998, the American Heart Association reclassified obesity as a major, modifiable risk factor for coronary heart disease.”
BackgroundKim, K., & Park, S. W. (2012) · The Korean Journal of Obesity · doi:10.7570/kjo.2012.21.4.197 · Cited by 12 · see citing works
Lee, B.-S., Kim, K.-A., Kim, J.-K., & Nho, H. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17197321 · Cited by 11 · see citing works
“Obesity is a major risk factor for the development of chronic diseases such as type 2 diabetes, hypertension, coronary artery disease, and heart failure [4,5].”
BackgroundMomentary predictors of dietary lapse from a mobile health weight loss intervention
Crochiere, R. J., Abber, S. R., Taylor, L. C., Sala, M., Schumacher, L. M., Goldstein, S. P., & Forman, E. M. (2021) · Journal of Behavioral Medicine · doi:10.1007/s10865-021-00264-4 · Cited by 10 · see citing works
“Clinically meaningful weight loss is associated with improvement in these and other co-morbid health conditions (Douketis & Sharma, 2005; Jensen et al., 2014; Wing et al., 2011).”
BackgroundWang, Y. (2010) · doi:10.1002/9781444323351.ch18 · Cited by 10 · see citing works
Influence of Obesity on Histological Tissue Structure of the Cardiovascular System in Horses
Siwińska, N., Janus, I., Żak, A., & Noszczyk-Nowak, A. (2022) · Animals · doi:10.3390/ani12060732 · Cited by 8 · see citing works
“In humans, obesity is also strongly associated with the development of major risk factors for atherosclerotic disease [11,12].”
BackgroundМЕТАБОЛИЧЕСКИЙ СИНДРОМ: ПАТОГЕНЕЗ, КРИТЕРИИ ДИАГНОСТИКИ И ЛЕЧЕНИЕ
Банзарова, Б. Г. У. И. Д., & В., А. Э. (2019) · Вестник Бурятского государственного университета. Медицина и фармация · doi:10.18101/2306-1995-2019-2-3-9 · Cited by 5 · see citing works
Fan, Y., Liu, J., Jin, L., Liu, Z., Han, L., Wang, Y., Zhang, Y., Shen, P., & Li, Z. (2022) · BMC Cardiovascular Disorders · doi:10.1186/s12872-022-02954-6 · Cited by 4 · see citing works
“Losing weight and keeping normal glucose metabolism can significantly reduce the incidence of cardio-cerebrovascular events and improve the long-term prognosis after surgeries [4, 5].”
BackgroundEpidemiology of Peripheral Artery Disease
Bekwelem, W., & Hirsch, A. T. (2017) · doi:10.1002/9781118775998.ch1 · Cited by 4 · see citing works
Singh, R. B., Jotwani, P. M., Gupta, S. S., et al. (2025) · Journal of Thrombosis and Thrombolysis · doi:10.1007/s11239-025-03200-4 · Cited by 3 · see citing works
“This may in part be due to the higher prevalence of arterial disease in elderly males and smokers, as smokers tend to have a lower BMI than non-smokers [ 23 ].”
The place of central-acting drugs in the algorithms of treatment of primary obesity
Logvinova, O., Galieva, M. O., Mazurina, N. V., & Troshina, E. A. (2017) · Obesity and metabolism · doi:10.14341/omet2017218-23 · Cited by 3 · see citing works
Cardiovascular death risk and body mass index in male and female Tumen City residents
Акимова, Е. В., Pushkarev, G. S., Гафаров, В. В., et al. (2013) · Russian Journal of Cardiology · doi:10.15829/1560-4071-2013-3-24-28 · Cited by 3 · see citing works
Evaluation of commercial weight‐loss programmes in Greece
Grammatikopoulou, M. G., Panayiotoglou, A., & Hassapidou, M. N. (2007) · International Journal of Consumer Studies · doi:10.1111/j.1470-6431.2007.00625.x · Cited by 2 · see citing works
Whether Obesity is Associated with Peripheral Arterial Disease
Maksimović, M. (2014) · Angiology Open Access · doi:10.4172/2329-9495.1000e104 · Cited by 2 · see citing works
“In old people, because of loss of lean body mass, BMI can remain unchanged or even decrease although adiposity increase [9].”
BackgroundEfecto de la restricción calórico-proteica sobre la adipogénesis
Negrete, D. R., Olivo, L. S., Yáñez, J. R., et al. (2013) · Biológicas Revista de la DES Ciencias Biológico Agropecuarias Universidad Michoacana de San Nicolás de Hidalgo · Cited by 1 · see citing works
[Overweight and obesity in the population over 20 years in urban Bamako (Mali)].
Ba, H., Menta, I., Camara, Y., Sangaré, I., Sidibé, N., Doumbia, S., & Diarra, M. B. (2014) · PubMed Central · doi:10.11604/pamj.2014.19.352.4381 · Cited by 1 · see citing works
“Surpoids (SP) et obésité (OB) sont liés à un accroissement du risque cardiovasculaire et le bénéfice potentiel de leur réduction a été souligné [1-4].”
Consuming Your Feelings: The Mechanisms Underpinning Emotional Eating
Pink, A. E. (2019) · doi:10.23889/suthesis.50331 · Cited by 1 · see citing works
Design, implementation and evaluation of a reduced cardiac rehabilitation program
Godoy, F., & Noelia, A. (2013) · Summit (Simon Fraser University) · Cited by 2 · see citing works
Aortales Remodeling bei Diät-induzierter Adipositas und mögliche pharmakologische Interventionen
Krüger, F. (2009) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-13076
Effect of Triacsin C on LPS-induced Inflammation in 3T3-L1 Adipocytes
Park, E.-J., & Spurlock, M. E. (2012) · Journal of the Korean Society of Food Science and Nutrition · doi:10.3746/jkfn.2012.41.2.283
“뿐만 아니라 비만은 동맥경화, 뇌졸중, 울혈성 심부 전증 등의 발병의 직접적인 위험인자로 알려져 있다(2).”
Katcher, H. I., Legro, R. S., Kunselman, A. R., Gillies, P. J., Demers, L. M., Bagshaw, D. M., & Kris‐Etherton, P. M. (2008)
Dadson, J. K. E. (2014) · YorkSpace (York University)
Lannin, U., Vaughan, C., Perry, I. J., & Browne, G. (2015) · PubMed
Omar, H. E.-D. M. (2015) · Journal of Diabetes and Obesity · doi:10.15436/2376-0494.15.018
“Obesity is carelessly associated with the premature development of atherosclerosis, increased risk of stroke, and development of congestive heart failure (Douketis & Sharma, 2005).”
BackgroundGrover, A., Nicholson, J. J., Huitink, J. M., & Riedel, B. (2016) · International Anesthesiology Clinics · doi:10.1097/aia.0000000000000114
Influence of the insulin effects enhancer to the body mass and subjective feeling of being healthy
Vuković, B. (2007) · Scripta Medica · doi:10.5937/scrimed0702083v
“), ali i druga stanja (menstrualne nepravilnosti, gestacioni dijabetes, kongenitalne malformacije, porodajne tegobe, gastroezofagealni refluks,) itd [8,9].”
BackgroundObesity: Disease of the contemporary man
Mrkobrada, N., Rodić, R., & Šormaz, L. (2006) · Scripta Medica · doi:10.5937/scrimed0602093m
“[1,2,20,29] Povećane vrijednosti BMI, kao faktor rizika, trebalo bi sagledati na isti način, kao i krvni pritisak i nivo holesterola.”
BackgroundThe development and initial evaluation of a weight specific quality of life instrument
Jefferson, R. (2020) · CLOK (University of Central Lancashire)
(2007) · Current Hypertension Reports · doi:10.1007/s11906-007-0046-y
Li, K. (2014) · RMIT Research Repository (RMIT University Library) · doi:10.25439/rmt.27340191
Fan, Y., Liu, J., Jin, L., Liu, Z., Han, L., Wang, Y., Zhang, Y., Shen, P., & Li, Z. (2022) · Figshare · doi:10.6084/m9.figshare.21629196
Fan, Y., Liu, J., Jin, L., Liu, Z., Han, L., Wang, Y., Zhang, Y., Shen, P., & Li, Z. (2022) · Figshare · doi:10.6084/m9.figshare.21629193
Surya, B. N., Vijayalakshmi, S., Palaniappan, P., et al. (2026) · International Journal of Noncommunicable Diseases · doi:10.4103/jncd.jncd_13_26
- Authors
- Douketis, J. D., & Sharma, A. M.
- Affiliations
- McMaster University (CA)
- Venue
- Seminars in Vascular Medicine
- Publisher
- Georg Thieme Verlag KG
- Published
- 2005-02
- Volume
- 5
- Issue
- 01
- Pages
- 25-33
- ISSN
- 1528-9648 (ISSN-L)
- 1529-3505
- OpenAlex
- W1984246339
- Cited by
- 77
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2023: 1 · 2022: 5 · 2021: 2 · 2020: 3 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 2 · 2015: 3 · 2014: 7 · 2013: 5 · 2012: 2
- FWCI
- 5.17
- Type
- journal article
- Language
- de
- Open access
- closed
- Locations
- Seminars in Vascular Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Keywords
- obesity, cardiovascular disease, weight loss, abdominal obesity, cardiovascular risk factors, hypertension, dyslipidemia, dysglycemia, coronary artery disease, stroke, ventricular function, peripheral arterial disease, venous thromboembolism, bariatric surgery, weight loss interventions, Look AHEAD trial
- MeSH terms
- Orlistat, Adult, Aged, Cardiovascular Diseases, Combined Modality Therapy, Diet, Reducing, Female, Humans, Lactones, Life Style, Male, Middle Aged, Obesity, Prognosis, Severity of Illness Index, Weight Loss, Exercise, Comorbidity, Body Mass Index, Prevalence, Survival Analysis, Randomized Controlled Trials as Topic, Age Distribution, Sex Distribution, Risk Assessment
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