The DOI matches its Crossref record.
The Quantitative Relation between Platelet Count and Hemorrhage in Patients with Acute Leukemia
Abstract
HEMORRHAGE is a frequent and often major complication in patients with acute leukemia. In addition to thrombocytopenia and its resulting coagulation defects disturbances of the hemostatic mechanism have been described in such patients.1 These include qualitative platelet defects2 3 4 and the presence of a fibrinolytic system and hypofibrinogenemia.5 , 6 Fever, which is presumably due to bacterial infection, has been found to be related to bleeding in patients with acute leukemia.6 , 7 This may result from the anticoagulant effect of bacterial polysaccharide demonstrated in vitro.8 Capillary damage resulting from lysins,9 anoxemia or leukemic infiltration has been postulated.10 Although any or all of these disturbances . . .
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Hematopoietic stem cell compartment: acute and late effects of radiation therapy and chemotherapy.
Mauch, P., Constine, L., Greenberger, J., Knospe, W., Sullivan, J., Liesveld, J. L., & Deeg, H. J. (1995) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/0360-3016(94)00430-s · Cited by 507
Practice Parameter for the Use of Fresh-Frozen Plasma, Cryoprecipitate, and Platelets
Cooper, E. S. (1994) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1994.03510340067036 · Cited by 295
Factors Associated with Fatal Hemoptysis in Cancer Patients
Panos, R. J., Barr, L. F., Walsh, T. J., & Silverman, H. J. (1988) · Chest · doi:10.1378/chest.94.5.1008 · Cited by 59
Metadata
- Authors
- Gaydos, L. A., Freireich, E. J., & Mantel, N.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1962-05-03
- Volume
- 266
- Issue
- 18
- Pages
- 905-909
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2339005914
- Cited by
- 527
- References
- 0
- FWCI
- 4.53
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Quantitative Relation between Platelet Count and Hemorrhage in Patients with Acute Leukemia. https://app.cochat.ai/papers/10.1056/nejm196205032661802
- The paper
- Gaydos, L. A., Freireich, E. J., & Mantel, N. (1962). The Quantitative Relation between Platelet Count and Hemorrhage in Patients with Acute Leukemia. New England Journal of Medicine. https://doi.org/10.1056/nejm196205032661802
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
