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Studies on the Epidemiology of Adverse Drug Reactions: An Evaluation of Penicillin Allergy
Abstract
THE remarkable lack of pharmacologic toxicity of penicillin is now well established, but penicillin hypersensitivity reactions have become a serious problem. A projection of statistics from some surveys estimates that 100 to 300 fatalities occur annually in the United States from reactions to penicillin,1 and an estimated 2,500,000 people in the United States are allergic to this widely used antibiotic.2 Adverse reactions to penicillin occur in 1 to 8 per cent of patients treated.3 The different reaction rates are probably related to numerous factors, including the difficulty in attributing reactions specifically to penicillin, particularly when several drugs are being administered . . .
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Citations
Cited by
Drug Allergy: An Updated Practice Parameter
(2010) · Annals of Allergy, Asthma & Immunology · doi:10.1016/j.anai.2010.08.002 · Cited by 957
HALLAS, J., HARVALD, B., GRAM, L. F., GRODUM, E., BRØSEN, K., HAGHFELT, T., & DAMSBO, N. (1990) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.1990.tb00199.x · Cited by 377
Absence of Cross-Reactivity between Sulfonamide Antibiotics and Sulfonamide Nonantibiotics
Strom, B. L., Schinnar, R., Apter, A. J., Margolis, D. J., Lautenbach, E., Hennessy, S., Bilker, W. B., & Pettitt, D. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022963 · Cited by 349
The Effect of Clinical Pharmacy Services on Patients with Essential Hypertension
McKENNEY, J. M., SLINING, J. M., HENDERSON, H. R., DEVINS, D., & BARR, M. (1973) · Circulation · doi:10.1161/01.cir.48.5.1104 · Cited by 340
SMITH, J. W., SEIDL, L. G., & CLUFF, L. E. (1966) · Annals of Internal Medicine · doi:10.7326/0003-4819-65-4-629 · Cited by 305
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Metadata
- Authors
- Smith, J. W., Johnson, J. E., & Cluff, L. E.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1966-05-05
- Volume
- 274
- Issue
- 18
- Pages
- 998-1002
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1988984702
- Cited by
- 316
- References
- 0
- FWCI
- 12.14
- Type
- journal article
- Language
- en
- Open access
- closed
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- Smith, J. W., Johnson, J. E., & Cluff, L. E. (1966). Studies on the Epidemiology of Adverse Drug Reactions: An Evaluation of Penicillin Allergy. New England Journal of Medicine. https://doi.org/10.1056/nejm196605052741804
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.