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Hyperuricemia in Primary and Renal Hypertension
Abstract
AN increased incidence of hyperuricemia in patients with primary hypertension has been cited in several reports.1 2 3 The present investigation of the population of the Hypertension-Nephritis Clinic of the Presbyterian Hospital in New York City confirms this observation among patients with either primary or renal hypertension, treated and untreated. The data from a related series of studies suggest that the hyperuricemia in both types of hypertension results from diminished renal excretion of urate. Altered lactic acid metabolism in hypertensive disease may account in part for the altered renal transport of uric acid.4 The results also raise the possibility that elevations of . . .
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Citations
Cited by
Feig, D. I., Soletsky, B., & Johnson, R. J. (2008) · JAMA · doi:10.1001/jama.300.8.924 · Cited by 914
Mechanisms of Disease: oxidative stress and inflammation in the pathogenesis of hypertension
Vaziri, N. D., & Rodríguez-Iturbe, B. (2006) · Nature Clinical Practice Nephrology · doi:10.1038/ncpneph0283 · Cited by 442
Matsuo, H., Takada, T., Ichida, K., Nakamura, T., Nakayama, A., Ikebuchi, Y., Ito, K., Kusanagi, Y., Chiba, T., Tadokoro, S., et al. (2009) · Science Translational Medicine · doi:10.1126/scitranslmed.3000237 · Cited by 437
Uric acid in metabolic syndrome: From an innocent bystander to a central player
Kanbay, M., Jensen, T., Solak, Y., Le, M., Roncal-Jimenez, C., Rivard, C., Lanaspa, M. A., Nakagawa, T., & Johnson, R. J. (2016) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2015.11.026 · Cited by 419
Uric acid, hyperuricemia and vascular diseases
Jin, M. (2012) · Frontiers in Bioscience · doi:10.2741/3950 · Cited by 406
Metadata
- Authors
- Cannon, P. J., Stason, W. B., Demartini, F. E., Sommers, S. C., & Laragh, J. H.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1966-09
- Volume
- 275
- Issue
- 9
- Pages
- 457-464
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2323300482
- Cited by
- 505
- References
- 0
- FWCI
- 7.25
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cannon, P. J., Stason, W. B., Demartini, F. E., Sommers, S. C., & Laragh, J. H. (1966). Hyperuricemia in Primary and Renal Hypertension. New England Journal of Medicine. https://doi.org/10.1056/nejm196609012750902
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
