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Cited by 382

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Hypertriglyceridemia: A Metabolic Consequence of Chronic Renal Failure

Bagdade, John D., Porte, Daniel, Bierman, Edwin L.·1968·New England Journal of Medicine

Abstract

Basal plasma triglyceride concentrations were supranormal in 13 undialyzed (164 ± 62 mg per 100 ml, mean ± S.D.) and 25 dialyzed (276 ± 250 mg per 100 ml) patients with non-nephrotic uremia. Basal immunoreactive insulin levels of both uremic groups were also higher than in nonuremic subjects of the same weight. In the dialyzed group triglyceride and immunoreactive insulin were directly related (r = 0.58, p<0.02), a relation suggesting that increased hepatic synthesis of triglyceride-rich lipoprotein may contribute to triglyceride elevation in uremia. In addition, peak postheparin lipolytic activity, an indirect estimate of tissue lipoprotein lipase and triglyceride removal capacity, was subnormal in both dialyzed and undialyzed uremic subjects. Hypertriglyceridemia appears to be a previously unrecognized consequence of non-nephrotic uremia. Alterations in both triglyceride production and assimilation may contribute to this abnormality.

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Crossref · 10.1056/nejm196807252790403

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Metadata

Authors
Bagdade, J. D., Porte, D., & Bierman, E. L.
Venue
New England Journal of Medicine
Published
1968-07-25
Volume
279
Issue
4
Pages
181-185
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W1980611267
Cited by
382
References
4
FWCI
10.15
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Hypertriglyceridemia: A Metabolic Consequence of Chronic Renal Failure. https://app.cochat.ai/papers/10.1056/nejm196807252790403
The paper
Bagdade, J. D., Porte, D., & Bierman, E. L. (1968). Hypertriglyceridemia: A Metabolic Consequence of Chronic Renal Failure. New England Journal of Medicine. https://doi.org/10.1056/nejm196807252790403

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.