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The Carrier Potential of Liposomes in Biology and Medicine: (Second of Two Parts)
Abstract
Interaction of Liposomes with CellsSince the demonstration that liposomes can transport entrapped agents into cultured cells and influence intracellular catabolism10 an ever-increasing number of mammalian and other cells have been found capable of associating in vitro with liposomes of diverse lipid composition (Table 1). Depending on the cell type, uptake of liposomes is temperature dependent,56 proportional to the lipid concentration56,90 and independent of pH (range, 6.8 to 8.7)90 and lipid composition,56 and it is more pronounced with monolamellar liposomes.91 With one exception,90 positive charge on the liposomal surface favors enhanced uptake (in the absence of . . .
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Cited by
Liposomal drug delivery systems: From concept to clinical applications
Allen, T. M., & Cullis, P. R. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.037 · Cited by 4,839
Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
Knop, K., Hoogenboom, R., Fischer, D., & Schubert, U. S. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.200902672 · Cited by 3,533
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
Sun, T., Zhang, Y. S., Pang, B., Hyun, D. C., Yang, M., & Xia, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201403036 · Cited by 2,164
New developments in liposomal drug delivery
Pattni, B. S., Chupin, V. V., & Torchilin, V. P. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00046 · Cited by 1,600
Kano, K., & Fendler, J. H. (1978) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(78)90048-2 · Cited by 353
Metadata
- Authors
- Gregoriadis, G.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1976-09-30
- Volume
- 295
- Issue
- 14
- Pages
- 765-770
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W3089887934
- Cited by
- 321
- References
- 0
- FWCI
- 16.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gregoriadis, G. (1976). The Carrier Potential of Liposomes in Biology and Medicine: (Second of Two Parts). New England Journal of Medicine. https://doi.org/10.1056/nejm197609302951406
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