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Smoking: A Risk Factor for Spontaneous Abortion
Abstract
We compared cigarette smoking during pregnancy among 574 women who aborted spontaneously (cases) and 320 women with delivery after at least 28 weeks' gestation (controls). Log-linear analysis was used to test the hypothesis that smoking is associated with spontaneous abortion. Several potentially confounding variables--namely, age at last menstrual period and the number of previous pregnancies ending in spontaneous abortion, in induced abortion and in live birth--were controlled in the analysis. Women who had aborted spontaneously reported smoking during pregnancy more often than those with delivery after 28 weeks' gestation: 41% of cases and 28% of controls smoked. The odds ratio for the highly significant association with smoking was 1.8. The association did not vary with age or previous obstetric events. We conclude that smoking during pregnancy is a risk factor for spontaneous abortion.
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Citations
Cited by
Behavioral and Neural Consequences of Prenatal Exposure to Nicotine
ERNST, M., MOOLCHAN, E. T., & ROBINSON, M. L. (2001) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200106000-00007 · Cited by 590
Maternal smoking during pregnancy and psychiatric adjustment in late adolescence
Fergusson, D. M., Woodward, L. J., & Horwood, L. J. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.8.721 · Cited by 396
Pineles, B. L., Park, E., & Samet, J. M. (2014) · American Journal of Epidemiology · doi:10.1093/aje/kwt334 · Cited by 387
ALCOHOL, SMOKING, AND INCIDENCE OF SPONTANEOUS ABORTIONS IN THE FIRST AND SECOND TRIMESTER
Harlap, S., & Shiono, P. H. (1980) · The Lancet · doi:10.1016/s0140-6736(80)90061-6 · Cited by 367
A Study of Occupational Exposure to Antineoplastic Drugs and Fetal Loss in Nurses
Selevan, S. G., Lindbohm, M.-L., Hornung, R. W., & Hemminki, K. (1985) · New England Journal of Medicine · doi:10.1056/nejm198511073131901 · Cited by 319
Metadata
- Authors
- Kline, J., Stein, Z. A., Susser, M., & Warburton, D.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1977-10-13
- Volume
- 297
- Issue
- 15
- Pages
- 793-796
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1983667127
- Cited by
- 227
- References
- 0
- FWCI
- 9.90
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kline, J., Stein, Z. A., Susser, M., & Warburton, D. (1977). Smoking: A Risk Factor for Spontaneous Abortion. New England Journal of Medicine. https://doi.org/10.1056/nejm197710132971501
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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