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Basic and Clinical Concepts Related to Vitamin D Metabolism and Action: (Second of Two Parts)
Abstract
Assays for Vitamin D MetabolitesThe basic advances in our understanding of the metabolism and mechanism of action of vitamin D not only are important in physiology and nutrition but have been successfully applied to the study of the pathophysiology of a myriad of metabolic bone disorders. Initially, assay procedures were developed to measure vitamin D metabolites. Competitive protein binding is the most widely used method for the assay of vitamin D metabolites, and various selective binding proteins, such as plasma carriers and intracellular receptors, have been employed. These measurements have led to increased comprehension of . . .
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Cited by
Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Bouillon, R., Carmeliet, G., Verlinden, L., van Etten, E., Verstuyf, A., Luderer, H. F., Lieben, L., Mathieu, C., & Demay, M. (2008) · Endocrine Reviews · doi:10.1210/er.2008-0004 · Cited by 1,783
Cloning and expression of full-length cDNA encoding human vitamin D receptor.
Baker, A. R., McDonnell, D. P., Hughes, M., Crisp, T. M., Mangelsdorf, D. J., Haussler, M. R., Pike, J. W., Shine, J., & O'Malley, B. W. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.10.3294 · Cited by 959
Self-citationVitamin D Deficiency Inhibits Pancreatic Secretion of Insulin
Norman, A. W., Frankel, B. J., Heldt, A. M., & Grodsky, G. M. (1980) · Science · doi:10.1126/science.6250216 · Cited by 720
Vitamin D, disease and therapeutic opportunities
Plum, L. A., & DeLuca, H. F. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd3318 · Cited by 477
Consensus statement on vitamin D status assessment and supplementation: Whys, whens, and hows
Giustina, A., Bilezikian, J. P., Adler, R. A., Banfi, G., Bikle, D. D., Binkley, N. C., Bollerslev, J., Bouillon, R., Brandi, M. L., Casanueva, F. F., et al. (2024) · Endocrine Reviews · doi:10.1210/endrev/bnae009 · Cited by 392
Metadata
- Authors
- Haussler, M. R., & McCain, T. A.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1977-11-10
- Volume
- 297
- Issue
- 19
- Pages
- 1041-1050
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W3090461134
- Cited by
- 254
- References
- 0
- FWCI
- 25.07
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Basic and Clinical Concepts Related to Vitamin D Metabolism and Action: (Second of Two Parts). https://app.cochat.ai/papers/10.1056/nejm197711102971906
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- Haussler, M. R., & McCain, T. A. (1977). Basic and Clinical Concepts Related to Vitamin D Metabolism and Action: (Second of Two Parts). New England Journal of Medicine. https://doi.org/10.1056/nejm197711102971906
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
