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Vitamin C and Iron
Abstract
Some of the first clues that ascorbic acid might be involved in iron metabolism came from careful clinical observations of the Bantu in South Africa.1 Habituated to the practice of drinking large quantities of beer that had been brewed in iron pots, these tribesmen ingested as much as 100 mg of iron each day. Curiously, they remained relatively immune to the detrimental effects of iron overload, although tissue hemosiderosis was readily documented. Most of the excess iron was found in reticuloendothelial cells, particularly in the spleen and liver, but the pancreas was also involved.2 In contrast to the situation in . . .
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Cited by
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The importance of free radicals and catalytic metal ions in human diseases.
Halliwell, B., & Gutteridge, J. M. C. (1985) · Molecular Aspects of Medicine · doi:10.1016/0098-2997(85)90001-9 · Cited by 941
EASL clinical practice guidelines for HFE hemochromatosis
European Association for the Study of the Liver (2010) · Journal of Hepatology · doi:10.1016/j.jhep.2010.03.001 · Cited by 587
Criteria and recommendations for vitamin C intake
Levine, M. (1999) · JAMA · doi:10.1001/jama.281.15.1415 · Cited by 559
Commentary: Vitamin C: Antioxidant or Pro-Oxidant In Vivo?
Halliwell, B. (1996) · Free Radical Research · doi:10.3109/10715769609149066 · Cited by 531
Metadata
- Authors
- Nienhuis, A. W.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1981-01-15
- Volume
- 304
- Issue
- 3
- Pages
- 170-171
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2080263495
- Cited by
- 162
- References
- 0
- FWCI
- 5.66
- Type
- journal article
- Language
- en
- Open access
- closed
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