The DOI matches its Crossref record.
Calcium and Ischemic Injury
Abstract
ISCHEMIC diseases of the heart, kidney, and brain continue to be the primary causes of mortality and morbidity in the United States and other Western industrialized nations. The magnitude of the problem has stimulated much research directed at identifying the proximate causes of ischemic cell death. It is hoped that a clear understanding of ischemia-induced derangements of cell function will allow more rational prevention and therapy.In the past two decades, many potentially damaging factors, such as ATP depletion, plasma-membrane phospholipid degradation, activation of autolytic systems, cellular acidosis, superoxide-induced membrane damage, and mitochondrial dysfunction, have been implicated as playing a . . .
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Citations
Cited by
Tator, C. H., & Fehlings, M. G. (1991) · Journal of Neurosurgery · doi:10.3171/jns.1991.75.1.0015 · Cited by 1,577
Siesjö, B. K., & Bengtsson, F. (1989) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1989.20 · Cited by 1,231
CNS energy metabolism as related to function
Ames, A. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(00)00038-2 · Cited by 663
Steenbergen, C., Murphy, E., Levy, L., & London, R. E. (1987) · Circulation Research · doi:10.1161/01.res.60.5.700 · Cited by 499
Tymianski, M., & Tator, C. H. (1996) · Neurosurgery · doi:10.1097/00006123-199606000-00028 · Cited by 313
Metadata
- Authors
- Epstein, F. H., Cheung, J. Y., Bonventre, J. V., Malis, C. D., & Leaf, A.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1986-06-26
- Volume
- 314
- Issue
- 26
- Pages
- 1670-1676
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1973408614
- Cited by
- 526
- References
- 0
- FWCI
- 31.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Calcium and Ischemic Injury. https://app.cochat.ai/papers/10.1056/nejm198606263142604
- The paper
- Epstein, F. H., Cheung, J. Y., Bonventre, J. V., Malis, C. D., & Leaf, A. (1986). Calcium and Ischemic Injury. New England Journal of Medicine. https://doi.org/10.1056/nejm198606263142604
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
