The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Stroke and Alcohol Consumption
Abstract
We conducted a retrospective case-control study to investigate a possible association between alcohol intake and stroke. Reported recent alcohol consumption and biochemical and hematologic markers of alcohol intake were examined for 230 patients with stroke (20 to 70 years old) and compared with concurrently collected data on controls matched for age, sex, and race. A single estimate of current intake was used as a measure of alcohol consumption. Among men, the relative risk of stroke (adjusted for hypertension, cigarette smoking, and medication) was lower in light drinkers (those consuming 10 to 90 g of alcohol weekly) than in nondrinkers (relative risk, 0.5), but was four times higher in heavy drinkers (consuming greater than or equal to 300 g weekly) than in nondrinkers. Because very few women in our study drank heavily, we were unable to determine whether heavy alcohol intake influenced the risk of stroke in women. With increasing serum concentrations of the biochemical markers of alcohol intake (aspartate aminotransferase, uric acid, and gamma-glutamyl transferase), we observed similar trends in the relative risk of stroke. Only the erythrocyte mean cell volume did not follow this pattern. We conclude that heavy alcohol consumption is an important and underrecognized independent risk factor for stroke in men, but our data are not adequate to settle the issue for women. Our conclusions are qualified by our reliance on reported recent alcohol consumption as the primary measure of intake.
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Citations
Cites
Case-Control Studies: Design, Conduct, Analysis.
Youkeles, L., & Schlesselman, J. J. (1983) · Journal of the American Statistical Association · doi:10.2307/2288156 · Cited by 2,346
Limitations of the Application of Fourfold Table Analysis to Hospital Data
Berkson, J. (1946) · Biometrics Bulletin · doi:10.2307/3002000 · Cited by 1,810
International Classification of Diseases
Peery, M. L. (2014) · Encyclopedia of Special Education · doi:10.1002/9781118660584.ese1248 · Cited by 979
Alcohol Consumption and Blood Pressure: Kaiser-Permanente Multiphasic Health Examination Data
Klatsky, A. L., Friedman, G. D., Siegelaub, A. B., & Gérard, M. J. (1977) · New England Journal of Medicine · doi:10.1056/nejm197705262962103 · Cited by 865
Arrhythmias and the “Holiday Heart”: Alcoholassociated cardiac rhythm disorders
Ettinger, P. O., Wu, C. F., Cruz, C. D. L., Weisse, A. B., Sultan Ahmed, S., & Regan, T. J. (1978) · American Heart Journal · doi:10.1016/0002-8703(78)90296-x · Cited by 609
Greenburg, G. A. (1981) · PubMed · Cited by 545
Bernadt, M. W., Taylor, C., Mumford, J., Smith, B., & Murray, R. M. (1982) · The Lancet · doi:10.1016/s0140-6736(82)91579-3 · Cited by 449
Alcohol and Coronary Heart Disease
MARMOT, M. G. (1984) · International Journal of Epidemiology · doi:10.1093/ije/13.2.160 · Cited by 359
Alcohol and Hemorrhagic Stroke: The Honolulu Heart Program
Donahue, R. P. (1986) · JAMA · doi:10.1001/jama.1986.03370170075038 · Cited by 348
PRESSOR EFFECT OF ALCOHOL IN HYPERTENSION
Potter, J. F., & Beevers, D. G. (1984) · The Lancet · doi:10.1016/s0140-6736(84)90060-6 · Cited by 289
Self-citation
Cited by
Kernan, W. N., Ovbiagele, B., Black, H. R., Bravata, D. M., Chimowitz, M. I., Ezekowitz, M. D., Fang, M. C., Fisher, M., Furie, K. L., Heck, D. V., et al. (2014) · Stroke · doi:10.1161/str.0000000000000024 · Cited by 5,170
Meschia, J. F., Bushnell, C., Boden-Albala, B., Braun, L. T., Bravata, D. M., Chaturvedi, S., Creager, M. A., Eckel, R. H., Elkind, M. S. V., Fornage, M., et al. (2014) · Stroke · doi:10.1161/str.0000000000000046 · Cited by 2,650
Stroke risk factors, genetics, and prevention
Boehme, A. K., Esenwa, C., & Elkind, M. S. V. (2017) · Circulation Research · doi:10.1161/circresaha.116.308398 · Cited by 1,952
The Links Between Education and Health
Ross, C. E., & Wu, C.-L. (1995) · American Sociological Review · doi:10.2307/2096319 · Cited by 1,943
Sacco, R. L., Adams, R., Albers, G., Alberts, M. J., Benavente, O., Furie, K., Goldstein, L. B., Gorelick, P., Halperin, J., Harbaugh, R., et al. (2006) · Stroke · doi:10.1161/01.str.0000199147.30016.74 · Cited by 1,873
Metadata
- Authors
- Gill, J. S., Zezulka, A. V., Shipley, M. J., Gill, S. K., & Beevers, D. G.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1986-10-23
- Volume
- 315
- Issue
- 17
- Pages
- 1041-1046
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2338943201
- Cited by
- 331
- References
- 32
- FWCI
- 19.51
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Stroke and Alcohol Consumption. https://app.cochat.ai/papers/10.1056/nejm198610233151701
- The paper
- Gill, J. S., Zezulka, A. V., Shipley, M. J., Gill, S. K., & Beevers, D. G. (1986). Stroke and Alcohol Consumption. New England Journal of Medicine. https://doi.org/10.1056/nejm198610233151701
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
