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Cited by 371

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Intermittent Coronary Occlusion in Acute Myocardial Infarction

Hackett, David, Davies, Graham, Chierchia, Sergio, Maseri, Attilio·1987·New England Journal of Medicine

Abstract

We performed continuous electrocardiographic ST-segment monitoring and serial coronary arteriography in 45 consecutive patients presenting in the early stages of acute myocardial infarction. During cardiac catheterization, 28 episodes of arteriographically confirmed coronary reopening and subsequent reocclusion were observed in 16 patients before (3 episodes) and during (25 episodes) continuous intracoronary infusion of streptokinase. In addition, ST-segment monitoring demonstrated 12 episodes of spontaneous transient return of the ST segment to the base line in eight patients between the time of admission and the performance of coronary arteriography. During arteriographically documented reocclusion, intracoronary isosorbide dinitrate (2 mg) reestablished the patency of the coronary artery within one to two minutes in 14 of 28 episodes that occurred in 11 of 16 patients. After streptokinase infusion, intracoronary administration of isosorbide dinitrate was followed by dilatation of the infarct-related stenosis from a mean value (+/- SD) of 1.12 +/- 0.3 mm (58.1 +/- 12.1 percent) to 1.33 +/- 0.4 mm (51.6 +/- 12.9 percent; P = 0.004). Spontaneous intermittent coronary recanalization and reocclusion resulting from a variable combination of thrombosis and vasoconstriction are frequent during the early phase of acute myocardial infarction. We propose that the combination of intracoronary streptokinase and isosorbide dinitrate may increase the rate of stable coronary recanalization.

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Metadata

Authors
Hackett, D., Davies, G., Chierchia, S., & Maseri, A.
Venue
New England Journal of Medicine
Published
1987-10-22
Volume
317
Issue
17
Pages
1055-1059
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2322445769
Cited by
371
References
12
FWCI
21.78
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Intermittent Coronary Occlusion in Acute Myocardial Infarction. https://app.cochat.ai/papers/10.1056/nejm198710223171704
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Hackett, D., Davies, G., Chierchia, S., & Maseri, A. (1987). Intermittent Coronary Occlusion in Acute Myocardial Infarction. New England Journal of Medicine. https://doi.org/10.1056/nejm198710223171704

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.