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Severe Herpesvirus Infections in an Adolescent without Natural Killer Cells
Abstract
NATURAL killer cells are a population of T-cell–receptornegative (CD3–) lymphocytes that spontaneously mediate the lysis of sensitive target cells. Natural killer cells are similar morphologically to large granular lymphocytes.1 They have the CD16 receptor for Fc portions of immunoglobulin molecules,2 and they express a member of the complement receptor–lymphocyte adhesion family of molecules, CD11b,3 on their cell surfaces, as well as the determinant NKH-1, which is specific to large granular lymphocytes.4 Although endogenous killer cells isolated from normal persons lyse only a limited range of highly sensitive target cells, both interferon and interleukin-2 can activate killer cells to lyse a . . .
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Cited by
NATURAL KILLER CELLS IN ANTIVIRAL DEFENSE: Function and Regulation by Innate Cytokines
Biron, C. A., Nguyen, K. B., Pien, G. C., Cousens, L. P., & Salazar-Mather, T. P. (1999) · Annual Review of Immunology · doi:10.1146/annurev.immunol.17.1.189 · Cited by 2,113
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Virgin, H. W., Wherry, E. J., & Ahmed, R. (2009) · Cell · doi:10.1016/j.cell.2009.06.036 · Cited by 1,031
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Laing, A. G., Lorenc, A., del Molino del Barrio, I., Das, A., Fish, M., Monin, L., Muñoz-Ruiz, M., McKenzie, D. R., Hayday, T. S., Francos-Quijorna, I., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-1038-6 · Cited by 946
The 3 major types of innate and adaptive cell-mediated effector immunity
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Lopez-Vergès, S., Milush, J. M., Schwartz, B. S., Pando, M. J., Jarjoura, J., York, V. A., Houchins, J. P., Miller, S., Kang, S.-M., Norris, P. J., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1110900108 · Cited by 822
Metadata
- Authors
- Biron, C. A., Byron, K. S., & Sullivan, J. L.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1989-06-29
- Volume
- 320
- Issue
- 26
- Pages
- 1731-1735
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2008221423
- Cited by
- 1,269
- References
- 0
- FWCI
- 11.36
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Severe Herpesvirus Infections in an Adolescent without Natural Killer Cells. https://app.cochat.ai/papers/10.1056/nejm198906293202605
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- Biron, C. A., Byron, K. S., & Sullivan, J. L. (1989). Severe Herpesvirus Infections in an Adolescent without Natural Killer Cells. New England Journal of Medicine. https://doi.org/10.1056/nejm198906293202605
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
