The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Cyclosporine
Abstract
ATHERAPEUTIC attack on the immune system is initiated in anticipation of or in response to immunologically mediated tissue damage. Drug regimens seek to inhibit selectively the T-cell and B-cell elements that permit adaptive, specific recognition of pathogenic, alien molecules and organisms while sparing the nonspecific granulocyte, monocyte, and macrophage elements that are responsible for phagocytosis, digestion, and metabolism of foreign materials. The prototype immunosuppressive drugs — azathioprine and adrenal corticosteroids — inhibit cell division of and cytokine generation by all elements of the immune system, respectively. In contradistinction, the immunosuppressive agent cyclosporine selectively inhibits adaptive immune responses. In spite of . . .
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Citations
Cites
Feutren, G., Assan, R., Karsenty, G., Du Rostu, H., Sirmai, J., Papoz, L., Vialettes, B., Vexiau, P., Rodier, M., Lallemand, A., et al. (1986) · The Lancet · doi:10.1016/s0140-6736(86)91943-4 · Cited by 448
Cited by
Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands
Schreiber, S. L. (1991) · Science · doi:10.1126/science.1702904 · Cited by 1,494
Kahan, B. D. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02480-6 · Cited by 913
Self-citationWinston, D. J., Pakrasi, A., & Busuttil, R. W. (1999) · Annals of Internal Medicine · doi:10.7326/0003-4819-131-10-199911160-00003 · Cited by 261
Lan, G.-B., Xie, X.-B., Peng, L.-K., Liu, L., Song, L., & Dai, H.-L. (2015) · BioMed Research International · doi:10.1155/2015/413169 · Cited by 46
Regulation of liver regeneration by interleukin-2 and its inhibitors: Cyclosporine A and FK 506
Tanaka, N., Yamamoto, H., Tatemoto, A., Urabe, T., & Orita, K. (1993) · International Journal of Immunopharmacology · doi:10.1016/0192-0561(93)90097-i · Cited by 31
Metadata
- Authors
- Oates, J. A., Wood, A. J. J., & Kahan, B. D.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1989-12-21
- Volume
- 321
- Issue
- 25
- Pages
- 1725-1738
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4255940022
- Cited by
- 1,359
- References
- 1
- FWCI
- 33.78
- Type
- journal article
- Language
- en
- Open access
- closed
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- Oates, J. A., Wood, A. J. J., & Kahan, B. D. (1989). Cyclosporine. New England Journal of Medicine. https://doi.org/10.1056/nejm198912213212507
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
