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Graft-versus-Host Disease
Abstract
DURING the 1980s the number of allogeneic bone marrow transplantations performed worldwide increased exponentially. In 1990 more than 4000 allogeneic transplantations were estimated to have been completed. This dramatic increase has been stimulated by the demonstration that bone marrow transplantation is an important therapeutic option for many patients with leukemia or lymphoma. In addition, the establishment of international marrow-donor registries has made HLA phenotypically matched marrow from unrelated donors available to patients who lack a suitable related donor. These developments have focused attention on the immunologic aspects of allogeneic transplantation and its chief complication, graft-versus-host disease (GVHD).Definition and Cause . . .
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Cited by
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Transplantation of Anergic Histoincompatible Bone Marrow Allografts
Guinan, E. C., Boussiotis, V. A., Neuberg, D., Brennan, L. L., Hirano, N., Nadler, L. M., & Gribben, J. G. (1999) · New England Journal of Medicine · doi:10.1056/nejm199906033402202 · Cited by 429
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Themeli, M., Rivière, I., & Sadelain, M. (2015) · Cell stem cell · doi:10.1016/j.stem.2015.03.011 · Cited by 179
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Morris, J. C., & Waldmann, T. A. (2000) · Annals of the Rheumatic Diseases · doi:10.1136/ard.59.suppl_1.i109 · Cited by 131
Metadata
- Authors
- Ferrara, J. L. M., & Deeg, H. J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1991-03-07
- Volume
- 324
- Issue
- 10
- Pages
- 667-674
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2094292853
- Cited by
- 1,219
- References
- 0
- FWCI
- 26.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ferrara, J. L. M., & Deeg, H. J. (1991). Graft-versus-Host Disease. New England Journal of Medicine. https://doi.org/10.1056/nejm199103073241005
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
