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Cited by 954

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

The Role of Interleukin-1 in Disease

Epstein, Franklin H., Dinarello, Charles A., Wolff, Sheldon M.·1993·New England Journal of Medicine

Abstract

The interleukin-1 family consists of three structurally related polypeptides. The first two are interleukin-1α and interleukin-1β, each of which has a broad spectrum of both beneficial and harmful biologic actions, and the third is interleukin-1-receptor antagonist, which inhibits the activities of interleukin-1. Among the properties of the two forms of interleukin-1 (α and β) is the ability to induce fever, sleep, anorexia, and hypotension. Interleukin-1 stimulates the release of pituitary hormones, increases the synthesis of collagenases, resulting in the destruction of cartilage, and stimulates the production of prostaglandins, leading to a decrease in the pain threshold. Interleukin-1 has also been . . .

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Crossref · 10.1056/nejm199301143280207

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Metadata

Authors
Epstein, F. H., Dinarello, C. A., & Wolff, S. M.
Venue
New England Journal of Medicine
Published
1993-01-14
Volume
328
Issue
2
Pages
106-113
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2332739634
Cited by
954
References
1
FWCI
31.10
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Role of Interleukin-1 in Disease. https://app.cochat.ai/papers/10.1056/nejm199301143280207
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Epstein, F. H., Dinarello, C. A., & Wolff, S. M. (1993). The Role of Interleukin-1 in Disease. New England Journal of Medicine. https://doi.org/10.1056/nejm199301143280207

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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