The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Advances in Diagnostic Imaging and Overestimations of Disease Prevalence and the Benefits of Therapy
Open accessAbstract
Over the past two decades a vast new armamentarium of diagnostic techniques has revolutionized the practice of medicine. The entire human body can now be imaged in exquisite anatomical detail. Computed tomography (CT), magnetic resonance imaging (MRI), and ultrasonography routinely “section” patients into slices less than a centimeter thick. Abnormalities can be detected well before they produce any clinical signs or symptoms. Undoubtedly, these technological advances have enhanced the physician's potential for understanding disease and treating patients. Unfortunately, these technological advances also create confusion that may ultimately be harmful to patients. Consider the case of prostate cancer. Although the prevalence . . .
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“The prevalence of any disease increases with the observer’s ability to detect the abnormalities associated with the disease (32).”
From Adrenal incidentaloma (2020) · cites this paper as [32]
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Boden, S. D., McCowin, P. R., Davis, D. O., Dina, T. S., Mark, A. S., & Wiesel, S. W. (1990) · Journal of Bone and Joint Surgery · doi:10.2106/00004623-199072080-00008 · Cited by 2,698
Boden, S. D., Davis, D. O., Dina, T. S., Patronas, N. J., & Wiesel, S. W. (1990) · Journal of Bone and Joint Surgery · doi:10.2106/00004623-199072030-00013 · Cited by 2,103
Feinstein, A. R., Sosin, D. M., & Wells, C. K. (1985) · New England Journal of Medicine · doi:10.1056/nejm198506203122504 · Cited by 1,554
Dorland??s Illustrated Medical Dictionary
Arey, L. B., Burrows, W. O., Greenhill, J. P., & Hewitt, R. M. (1957) · The American Journal of the Medical Sciences · doi:10.1097/00000441-195712000-00043 · Cited by 1,347
Mammographic screening and mortality from breast cancer: the Malmö mammographic screening trial.
Andersson, I., Aspegren, K., Janzon, L., Landberg, T. G., Lindholm, K., Linell, F., Ljungberg, O., Ranstam, J., & Sigfússon, B. F. (1988) · BMJ · doi:10.1136/bmj.297.6654.943 · Cited by 916
Randomized versus historical controls for clinical trials
Sacks, H., Chalmers, T. C., & Smith, H. (1982) · The American Journal of Medicine · doi:10.1016/0002-9343(82)90815-4 · Cited by 834
Cooner, W. H., Mosley, B. R., Rutherford, C. L., Beard, J. H., Pond, H. S., Terry, W. J., Igel, T. C., & Kidd, D. D. (1990) · The Journal of Urology · doi:10.1016/s0022-5347(17)40211-4 · Cited by 765
Periodic mammographic follow-up of probably benign lesions: results in 3,184 consecutive cases.
Sickles, E. A. (1991) · Radiology · doi:10.1148/radiology.179.2.2014293 · Cited by 556
(1993) · Cancer Causes & Control · doi:10.1007/bf00052433 · Cited by 437
Breast cancer and atypia among young and middle-aged women: a study of 110 medicolegal autopsies
Nielsen, M. B., Thomsen, J. L., Primdahl, S., Dyreborg, U., & Andersen, J. A. (1987) · British Journal of Cancer · doi:10.1038/bjc.1987.296 · Cited by 415
Research works printed but not linked: 9
- Cole P, 1980, J Natl Cancer Inst, 64, 1263
- Bottinger LE, 1964, Acta Chir Scand, 127, 158
- Grinnell RS, 1958, Int Abstr Surg, 106, 519
- Miller AB. Screening and detection. In: Bland KI, Copeland EM, eds. The breast. Philadelphia: W.B. Saunders, 1991:419.
- National Center for Health Statistics. Vital statistics of the United States, 1986. Vol. 2. Mortality. Part B. Washington, D.C.: Government Printing Office, 1986. (DHHS publication no. (PHS) 88-1114.)
- Frost JK, 1984, Am Rev Respir Dis, 130, 549
- Flehinger BJ, 1984, Am Rev Respir Dis, 130, 555
- Fontana RS, 1984, Am Rev Respir Dis, 130, 561
- Diagnostic and spectral markers. In: Feinstein AR. Clinical epidemiology: the architecture of clinical research. Philadelphia: W.B. Saunders, 1985:597-631.
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Shore, E. M. (2009) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.1159773.630443
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Zhou, X., Obuchowski, N. A., & McClish, D. K. (2011) · Wiley series in probability and statistics · doi:10.1002/9780470906514.refs
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(2005) · Bulletin des Médecins Suisses · doi:10.4414/saez.2005.10974
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Benninghoff, B., Birkenmeier, J., Folkman, J., Hager, E. D., Hajeck-Lang, B., Irmey, G., Kaltofen, S., Klingmüller, M., Kraft, K., Matthei, S., et al. (2006) · Elsevier eBooks · doi:10.1016/b978-343756420-8.50016-0
Ettema, R. H., Luining, W. I., Vis, A. N., & van den Bergh, R. V. D. (2024) · Tijdschrift voor Urologie · doi:10.1007/s13629-024-00420-w
Yoo, J.-Y., Leem, D. E., Kim, B. R., Kim, T. H., Kim, S. W., & Chung, J. H. (2025) · Endocrinology and Metabolism · doi:10.3803/enm.2024.2214
Point of Care Nanobiosensing Devices: Construction to Diagnosis of Diseases
Karadag, B., Kilic, N. M., & Odaci, D. (2024) · Springer eBooks · doi:10.1007/978-981-97-7445-6_40
Schmaling, K. B., & Kaplan, R. M. (2025) · Cambridge University Press eBooks · doi:10.1017/9781009391733.016
Schmaling, K. B., & Kaplan, R. M. (2025) · Cambridge University Press eBooks · doi:10.1017/9781009391733.019
Evidence categories in systematic assessment of cancer overdiagnosis
Барчук, А. А., Nordlund, N. K., Halme, A. L. E., & Tikkinen, K. A. O. (2025) · BMJ Evidence-Based Medicine · doi:10.1136/bmjebm-2024-113529
Nilsson, U. W. (2007) · DiVA (Linkoping University)
Angiogenesis regulation in hormone dependent breast- and ovarian cancer
Bendrik, C. (2011) · DiVA (Linkoping University)
Surgical Management of Medullary Thyroid Cancer
Machens, A., & Dralle, H. (2026) · Springer eBooks · doi:10.1007/978-3-032-13130-0_22
Dima, A. M., Lixandru-Petre, I.-O., Iorga, D., Pîrcălăbioru, G. G., Terzea, D. C., Goldstein, A. L., Iliescu, F. S., Dascălu, M., Muşat, M., & Iliescu, C. (2026) · Cancers · doi:10.3390/cancers18061036
Xiu, D., Hu, Y., Wang, Y., Cheng, K., Ye, Z., Liu, L., & Cheng, M. (2026) · Journal of Radiation Research and Applied Sciences · doi:10.1016/j.jrras.2026.102359
(2026) · Wiley series in probability and statistics · doi:10.1002/9781394220243.biblio
Rasouli, N., Orsmaa, L., Saukkoriipi, M., Kangas, J. A., Järnstedt, J., Sahlsten, J., Kaski, K. K., & Raisamo, R. (2026) · Applied Sciences · doi:10.3390/app16147067
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Porzsolt, F. (1995) · Springer eBooks · doi:10.1007/978-3-642-79214-4_32
Metadata
- Authors
- Black, W. C., & Welch, H. G.
- Affiliations
- Dartmouth College (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1993-04-29
- Volume
- 328
- Issue
- 17
- Pages
- 1237-1243
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2327648646
- Cited by
- 547
- References
- 47
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 7 · 2023: 13 · 2022: 7 · 2021: 13 · 2020: 11 · 2019: 9 · 2018: 14 · 2017: 18 · 2016: 16 · 2015: 23 · 2014: 16 · 2013: 11 · 2012: 15
- FWCI
- 22.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Urology › Prostate Cancer Diagnosis and Treatment
- Health Sciences › Health Professions › General Health Professions › Healthcare cost, quality, practices
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiology practices and education
- Keywords
- diagnostic imaging, disease prevalence, prostate cancer, computed tomography, magnetic resonance imaging, ultrasonography, incidental finding
- MeSH terms
- Aged, Breast Neoplasms, Decision Making, Diagnostic Imaging, Female, Humans, Male, Middle Aged, Neoplasms, Thyroid Neoplasms, Bias, Prevalence, Aortic Aneurysm, Abdominal
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