The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Treatment of Parkinson's Disease
Abstract
Parkinson's disease (idiopathic parkinsonism or paralysis agitans) is characterized clinically by progressive tremor, bradykinesia, and rigidity and pathologically by degeneration of the dopaminergic nigrostriatal pathway, decreases in the striatal concentration of dopamine, and the presence of laminated inclusions (Lewy bodies) in neurons of the substantia nigra. The cause (or causes) of Parkinson's disease is not known, and the pathophysiology is poorly understood. However, there is a considerable body of knowledge concerning the disturbances of synaptic function. Degeneration of the nigrostriatal pathway leads to the depletion of the neurotransmitter dopamine. Since dopamine does not readily cross the blood-brain barrier, the major . . .
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Cites
Parkinsonism: onset, progression, and mortality
Hoehn, M. M., & Yahr, M. D. (1967) · Neurology · doi:10.1212/wnl.17.5.427 · Cited by 12,107
Nutt, J. G., Woodward, W. R., Carter, J. H., & Trotman, T. L. (1989) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.52.4.481 · Cited by 49
Cited by
Peto, V., Jenkinson, C., Fitzpatrick, R., & Greenhall, R. (1995) · Quality of Life Research · doi:10.1007/bf02260863 · Cited by 1,204
MiR-155: An Important Regulator of Neuroinflammation
Zingale, V. D., Gugliandolo, A., & Mazzon, E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010090 · Cited by 163
Ultrasound targeted CNS gene delivery for Parkinson's disease treatment
Fan, C.-H., Lin, C.-Y., Liu, H.-L., & Yeh, C.-K. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.07.004 · Cited by 97
Metadata
- Authors
- Wood, A. J. J., & Calne, D. B.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1993-09-30
- Volume
- 329
- Issue
- 14
- Pages
- 1021-1027
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2330445375
- Cited by
- 183
- References
- 2
- FWCI
- 7.16
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wood, A. J. J., & Calne, D. B. (1993). Treatment of Parkinson's Disease. New England Journal of Medicine. https://doi.org/10.1056/nejm199309303291408
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
