The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Disorders of Aldosterone Biosynthesis and Action
Abstract
Patients with Addison's disease excrete excessive amounts of sodium in the urine but retain potassium, thus becoming hyponatremic and hyperkalemic. Early studies demonstrated that the problems could be ameliorated in humans and animals by administering extracts from adrenal glands1,2. These extracts were presumed to contain hormones with sodium-retaining, or mineralocorticoid, properties. The existence of distinct mineralocorticoids was, however, not proved until a novel steroid with potent mineralocorticoid activity was isolated3. This hormone was named aldosterone to acknowledge its unique structural feature, an aldehyde group at C18.This article reviews conditions of mineralocorticoid deficiency or excess, concentrating on . . .
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Cites
Inositol trisphosphate and calcium signalling
Berridge, M. J. (1993) · Nature · doi:10.1038/361315a0 · Cited by 6,545
Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters
Mosser, J., Douar, A.-M., Sarde, C.-O., Kioschis, P., Feil, R., Moser, H., Poustka, A.-M., Mandel, J.-L., & Aubourg, P. (1993) · Nature · doi:10.1038/361726a0 · Cited by 1,202
Lifton, R. P., Dluhy, R. G., Powers, M., Rich, G. M., Cook, S., Ulick, S., & Lalouel, J.-M. (1992) · Nature · doi:10.1038/355262a0 · Cited by 1,158
Speiser, P. W., Dupont, J., Zhu, D., Serrat, J., Buegeleisen, M., Tusie-Luna, M. T., Lesser, M., New, M. I., & White, P. C. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115897 · Cited by 572
Self-citation21-hydroxylase, a major autoantigen in idiopathic Addison's disease
Winqvist, O., Karlsson, F. A., & Kämpe, O. (1992) · The Lancet · doi:10.1016/0140-6736(92)91829-w · Cited by 410
The use of ketoconazole as an inhibitor of steroid production
Oates, J. A., Wood, A. J. J., & Sonino, N. (1987) · New England Journal of Medicine · doi:10.1056/nejm198709243171307 · Cited by 395
The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex
Curnow, K. M., Tusie-Luna, M.-T., Pascoe, L., Natarajan, R., Gu, J.-L., Nadler, J. L., & White, P. C. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-10-1513 · Cited by 362
Self-citationA new isoform of 11 beta-hydroxysteroid dehydrogenase in aldosterone target cells
Rusvai, E., & Náray-Fejes-Tóth, A. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)82044-0 · Cited by 248
Adrenoleukodystrophy: Phenotypic variability and implications for therapy
Moser, H. W., Moser, A. B., Smith, K. D., Bergin, A., Borel, J., Shankroff, J., Stine, O. C., Merette, C., Ott, J., Krivit, W., et al. (1992) · Journal of Inherited Metabolic Disease · doi:10.1007/bf01799621 · Cited by 239
Rhéaume, E., Simard, J., Morel, Y., Mebarki, F., Zachmann, M., Forest, M. G., New, M. I., & Labrie, F. (1992) · Nature Genetics · doi:10.1038/ng0792-239 · Cited by 235
Cited by
Angiotensin II and Potassium Regulate Human CYP11B2 Transcription through Common cis-Elements
Clyne, C. D., Zhang, Y., Slutsker, L., Mathis, J. M., White, P. C., & Rainey, W. E. (1997) · Molecular Endocrinology · doi:10.1210/mend.11.5.9920 · Cited by 202
Self-citationAdrenal Steroidogenesis and Congenital Adrenal Hyperplasia
Turcu, A. F., & Auchus, R. J. (2015) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2015.02.002 · Cited by 177
Steroidogenic enzyme gene expression in the human heart
Kayes-Wandover, K. M. (2000) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.7.2519 · Cited by 174
Kelly, T. N., Takeuchi, F., Tabara, Y., Edwards, T. L., Kim, Y. J., Chen, P., Li, H., Wu, Y., Yang, C.-F., Zhang, Y., et al. (2013) · Hypertension · doi:10.1161/hypertensionaha.113.01148 · Cited by 66
Yang, M., & White, P. C. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgae535 · Cited by 20
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Metadata
- Authors
- Epstein, F. H., & White, P. C.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1994-07-28
- Volume
- 331
- Issue
- 4
- Pages
- 250-258
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2335083369
- Cited by
- 225
- References
- 14
- FWCI
- 4.18
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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