The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Unethical Trials of Interventions to Reduce Perinatal Transmission of the Human Immunodeficiency Virus in Developing Countries
Abstract
It has been almost three years since the Journal 1 published the results of AIDS Clinical Trials Group (ACTG) Study 076, the first randomized, controlled trial in which an intervention was proved to reduce the incidence of human immunodeficiency virus (HIV) infection. The antiretroviral drug zidovudine, administered orally to HIV-positive pregnant women in the United States and France, administered intravenously during labor, and subsequently administered to the newborn infants, reduced the incidence of HIV infection by two thirds.2 The regimen can save the life of one of every seven infants born to HIV-infected women.Because of these findings, the study was . . .
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Cites
Angell, M. (1988) · New England Journal of Medicine · doi:10.1056/nejm198810203191608 · Cited by 143
Cited by
What Makes Clinical Research Ethical?
Emanuel, E. J. (2000) · JAMA · doi:10.1001/jama.283.20.2701 · Cited by 2,710
What Makes Clinical Research in Developing Countries Ethical? The Benchmarks of Ethical Research
Emanuel, E. J., Wendler, D., Killen, J., & Grady, C. (2004) · The Journal of Infectious Diseases · doi:10.1086/381709 · Cited by 966
The Ethics of Clinical Research in the Third World
Angell, M. (1997) · New England Journal of Medicine · doi:10.1056/nejm199709183371209 · Cited by 863
Assessing the Gold Standard — Lessons from the History of RCTs
Bothwell, L. E., Greene, J. A., Podolsky, S. H., & Jones, D. S. (2016) · New England Journal of Medicine · doi:10.1056/nejmms1604593 · Cited by 664
(2002) · The Lancet · doi:10.1016/s0140-6736(02)08214-4 · Cited by 459
Metadata
- Authors
- Lurie, P., & Wolfe, S. M.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1997-09-18
- Volume
- 337
- Issue
- 12
- Pages
- 853-856
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1973698029
- Cited by
- 882
- References
- 1
- FWCI
- 27.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lurie, P., & Wolfe, S. M. (1997). Unethical Trials of Interventions to Reduce Perinatal Transmission of the Human Immunodeficiency Virus in Developing Countries. New England Journal of Medicine. https://doi.org/10.1056/nejm199709183371212
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
