The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Respiratory Function of Hemoglobin
Abstract
Hemoglobin is essential for oxygen transport, and the study of its structure and function has led to numerous discoveries that have shaped modern biologic science.1 This review will examine how hemoglobin actively regulates oxygen transport and will illustrate the clinical and physiologic importance of this regulation.Oxyhemoglobin Dissociation CurveThe oxyhemoglobin dissociation curve describes the relation between the oxygen saturation or content of hemoglobin and the oxygen tension at equilibrium. Bohr2,3 first showed that the dissociation curve was sigmoid-shaped, leading Hill4 to postulate that there were multiple oxygen-binding sites on hemoglobin and to derive an empirical approximation of the . . .
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Cites
On the nature of allosteric transitions: A plausible model
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S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control
Jia, L., Bonaventura, C., Bonaventura, J., & Stamler, J. S. (1996) · Nature · doi:10.1038/380221a0 · Cited by 1,601
Blood Flow Regulation by S -Nitrosohemoglobin in the Physiological Oxygen Gradient
Stamler, J. S., Jia, L., Eu, J. P., McMahon, T. J., Demchenko, I. T., Bonaventura, J., Gernert, K., & Piantadosi, C. A. (1997) · Science · doi:10.1126/science.276.5321.2034 · Cited by 1,050
Hemoglobin: Molecular, Genetic and Clinical Aspects.
(1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-105-5-820_2 · Cited by 1,006
Bohr, C., Hasselbalch, K., & Krogh, A. (1904) · Skandinavisches Archiv Für Physiologie · doi:10.1111/j.1748-1716.1904.tb01382.x · Cited by 629
Exercise‐induced arterial hypoxaemia in healthy human subjects at sea level.
Dempsey, J. A., Hanson, P. G., & Henderson, K. S. (1984) · The Journal of Physiology · doi:10.1113/jphysiol.1984.sp015412 · Cited by 555
Digital computer subroutine for the conversion of oxygen tension into saturation.
Kelman, G. R. (1966) · Journal of Applied Physiology · doi:10.1152/jappl.1966.21.4.1375 · Cited by 537
Pulmonary gas exchange in humans exercising at sea level and simulated altitude
Wagner, P. D., Gale, G. E., Moon, R. E., Torre-Bueno, J. R., Stolp, B. W., & Saltzman, H. A. (1986) · Journal of Applied Physiology · doi:10.1152/jappl.1986.61.1.260 · Cited by 487
The absorption and dissociation of carbon dioxide by human blood
Christiansen, J., Douglas, C. G., & Haldane, J. S. (1914) · The Journal of Physiology · doi:10.1113/jphysiol.1914.sp001659 · Cited by 466
Effect of altitude on oxygen binding by hemoglobin and on organic phosphate levels
Lenfant, C., Torrance, J., English, E., Finch, C. A., Reynafarje, C., Ramos, J., & Faura, J. (1968) · Journal of Clinical Investigation · doi:10.1172/jci105948 · Cited by 418
Cited by
Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control
Huang, Z. (2005) · Journal of Clinical Investigation · doi:10.1172/jci24650 · Cited by 520
Risks and Benefits of Nicotine to Aid Smoking Cessation in Pregnancy
Dempsey, D. A., & Benowitz, N. L. (2001) · Drug Safety · doi:10.2165/00002018-200124040-00005 · Cited by 346
Optically Active Porphyrin and Phthalocyanine Systems
Lu, H., & Kobayashi, N. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00588 · Cited by 323
Controlled oxygen delivery to power tissue regeneration
Zoneff, E., Wang, Y., Jackson, C., Smith, O., Duchi, S., Onofrillo, C., Farrugia, B., Moulton, S. E., Williams, R., Parish, C., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-48719-x · Cited by 89
Prediction of Protein Ion–Ligand Binding Sites with ELECTRA
Essien, C., Jiang, L., Wang, D., & Xu, D. (2023) · Molecules · doi:10.3390/molecules28196793 · Cited by 5
Metadata
- Authors
- Hsia, C. C. W.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1998-01-22
- Volume
- 338
- Issue
- 4
- Pages
- 239-248
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2338041258
- Cited by
- 300
- References
- 34
- FWCI
- 3.16
- Type
- journal article
- Language
- en
- Open access
- closed
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