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Cited by 715

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Cellular Origin of Human B-Cell Lymphomas

Küppers, Ralf, Klein, Ulf, Hansmann, Martin-Leo, Rajewsky, Klaus·1999·New England Journal of Medicine

Abstract

The origin of human lymphomas has been studied by various approaches, including histology and immunophenotyping. In some types of lymphoma these studies suggested the cellular origin, but in many instances the origin could not be identified. When somatic mutations of the genes for the variable region of the B-lymphocyte antigen receptor proved to be a hallmark of germinal-center B cells and their descendants, sequence analysis of the variable-region genes of B-cell lymphomas offered a molecular approach to studying the origin of the tumors. Before discussing the results of these studies, we outline the human peripheral B-cell repertoire and its generation. . . .

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Crossref · 10.1056/nejm199911113412007

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Metadata

Authors
Küppers, R., Klein, U., Hansmann, M.-L., & Rajewsky, K.
Venue
New England Journal of Medicine
Published
1999-11-11
Volume
341
Issue
20
Pages
1520-1529
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W1975100378
Cited by
715
References
2
FWCI
25.50
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Cellular Origin of Human B-Cell Lymphomas. https://app.cochat.ai/papers/10.1056/nejm199911113412007
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Küppers, R., Klein, U., Hansmann, M.-L., & Rajewsky, K. (1999). Cellular Origin of Human B-Cell Lymphomas. New England Journal of Medicine. https://doi.org/10.1056/nejm199911113412007

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.