The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Innate Immunity
Abstract
The immune system has traditionally been divided into innate and adaptive components, each with a different function and role. The adaptive component is organized around two classes of specialized cells, T cells and B cells. Since each lymphocyte displays a single kind of structurally unique receptor, the repertoire of antigen receptors in the entire population of lymphocytes is very large and extremely diverse. The size and diversity of this repertoire increase the probability that an individual lymphocyte will encounter an antigen that binds to its receptor, thereby triggering activation and proliferation of the cell. This process, termed clonal selection, accounts . . .
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Citations
Cites
Innate Immunity: The Virtues of a Nonclonal System of Recognition
Medzhitov, R., & Janeway, C. A. (1997) · Cell · doi:10.1016/s0092-8674(00)80412-2 · Cited by 2,434
Self-citation
Cited by
Raetz, C. R. H., & Whitfield, C. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.110601.135414 · Cited by 4,404
Adverse childhood experiences, allostasis, allostatic load and age-related disease
Danese, A., & McEwen, B. S. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.08.019 · Cited by 2,140
HIF-1α is essential for myeloid cell-mediated inflammation
Cramer, T., Yamanishi, Y., Clausen, B. E., Förster, I., Pawlinski, R., Mackman, N., Haase, V. H., Jaenisch, R., Corr, M., Nizet, V., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00154-5 · Cited by 2,046
Complement and its role in innate and adaptive immune responses
Dunkelberger, J. R., & Song, W.-C. (2010) · Cell Research · doi:10.1038/cr.2009.139 · Cited by 1,932
Antigen Presentation and T Cell Stimulation by Dendritic Cells
Guermonprez, P., Valladeau, J., Zitvogel, L., Théry, C., & Amigorena, S. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.100301.064828 · Cited by 1,926
Metadata
- Authors
- Medzhitov, R., & Janeway, C.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2000-08-03
- Volume
- 343
- Issue
- 5
- Pages
- 338-344
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4236842068
- Cited by
- 1,825
- References
- 1
- FWCI
- 28.13
- Type
- journal article
- Language
- en
- Open access
- closed
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- Medzhitov, R., & Janeway, C. (2000). Innate Immunity. New England Journal of Medicine. https://doi.org/10.1056/nejm200008033430506
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
