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Cited by 1,926

The DOI matches its Crossref record; 295 of the 295 references it cites were found in a registry or an index.

Antigen Presentation and T Cell Stimulation by Dendritic Cells

Guermonprez, Pierre, Valladeau, Jenny, Zitvogel, Laurence, Théry, Clotilde, Amigorena, Sebastian·2002·Annual Review of Immunology

Abstract

Dendritic cells take up antigens in peripheral tissues, process them into proteolytic peptides, and load these peptides onto major histocompatibility complex (MHC) class I and II molecules. Dendritic cells then migrate to secondary lymphoid organs and become competent to present antigens to T lymphocytes, thus initiating antigen-specific immune responses, or immunological tolerance. Antigen presentation in dendritic cells is finely regulated: antigen uptake, intracellular transport and degradation, and the traffic of MHC molecules are different in dendritic cells as compared to other antigen-presenting cells. These specializations account for dendritic cells' unique role in the initiation of immune responses and the induction of tolerance.

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Crossref · 10.1146/annurev.immunol.20.100301.064828

Cites

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Citations

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Metadata

Authors
Guermonprez, P., Valladeau, J., Zitvogel, L., Théry, C., & Amigorena, S.
Venue
Annual Review of Immunology
Published
2002-04
Volume
20
Issue
1
Pages
621-667
ISSN
  • 0732-0582 (ISSN-L)
  • 1545-3278
OpenAlex
W2170240282
Cited by
1,926
References
295
FWCI
5.52
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Antigen Presentation and T Cell Stimulation by Dendritic Cells. https://app.cochat.ai/papers/10.1146/annurev.immunol.20.100301.064828
The paper
Guermonprez, P., Valladeau, J., Zitvogel, L., Théry, C., & Amigorena, S. (2002). Antigen Presentation and T Cell Stimulation by Dendritic Cells. Annual Review of Immunology. https://doi.org/10.1146/annurev.immunol.20.100301.064828

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.