Cited by 114SARS-CoV-2 and COVID-19 ResearchCOVID-19 epidemiological studiesCOVID-19 Clinical Research Studies

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Waning mRNA-1273 Vaccine Effectiveness against SARS-CoV-2 Infection in Qatar

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Abu-Raddad, Laith J., Chemaitelly, Hiam, Bertollini, Roberto·2022·New England Journal of Medicine

Abstract

vaccine was associated with neutralization titers against the omicron variant that were 20.0 times higher than those assessed after the second dose of vaccine, and these titers may substantially reduce the risk of breakthrough infection.The decline in neutralization of the omicron variant 6 months after the booster injection was similar to the decline in neutralization titers against the D614G variant 7 months after the second dose.The limitations of our study include small sample sets that may not reflect neutralization in diverse populations, differences in the length of time before boosting among the groups, and a lack of post-boost efficacy data.These limitations may be addressed in further studies.

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Metadata

Authors
Abu-Raddad, L. J., Chemaitelly, H., & Bertollini, R.
Affiliations
  • Weill Cornell Medical College in Qatar (QA)
  • Ministry of Public Health (QA)
Corresponding author
Abu-Raddad, Laith J.
Venue
New England Journal of Medicine
Published
2022-03-17
Volume
386
Issue
11
Pages
1091-1093
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W4210488818
Cited by
114
References
5
Citations by year
2026: 8 · 2025: 16 · 2024: 13 · 2023: 26 · 2022: 51
FWCI
12.96
Type
journal article
Language
en
Open access
Locations
  • New England Journal of Medicine (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Qatar University QSpace (Qatar University) (submittedVersion)
Funders
  • Biomedical Research Program and the Biostatistics, Epidemiology, and Biomathematics Research Core at Weill Cornell Medicine–Qatar
  • Qatar Ministry of Public Health, Hamad Medical Corporation, Sidra Medicine, Qatar Genome Program, and Qatar University Biomedical Research Center
Topics
  • Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
  • Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
  • Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
Keywords
mRNA-1273 vaccine, SARS-CoV-2, Omicron variant, neutralizing antibodies, waning vaccine effectiveness, breakthrough infection, booster vaccination, D614G mutation, vaccine durability, Qatar
MeSH terms
COVID-19, COVID-19 Vaccines, Vaccine Efficacy, 2019-nCoV Vaccine mRNA-1273, Female, Humans, Immunization, Secondary, Male, Qatar, Case-Control Studies

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