Cited by 85Pancreatitis Pathology and TreatmentLipid metabolism and disordersLipoproteins and Cardiovascular Health

Volanesorsen to Prevent Acute Pancreatitis in Hypertriglyceridemia

Alexander, Veronica J., Karwatowska-Prokopczuk, Ewa, Prohaska, Thomas A., Li, Lu, Geary, Richard S., Gouni-Berthold, Ioanna, Oral, Elif A., Hegele, Robert A. +3 more·2024·New England Journal of Medicine

Integrity signals

Registry

Crossref · 10.1056/nejmc2306575

Cites

4 of 4 references verified0 citation errors · 0 not checkable

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  • The trial findings are consistent with a meta-analysis of three randomized, placebo-controlled trials of volanesorsen, which showed an association between treatment and a reduction in the incidence of acute pancreatitis.

    “Our findings are consistent with the results of a meta-analysis of three randomized, placebocontrolled trials of volanesorsen, which showed an association between treatment and a reduction in the incidence of acute pancreatitis. 35”

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Authors
Alexander, V. J., Karwatowska-Prokopczuk, E., Prohaska, T. A., Li, L., Geary, R. S., Gouni-Berthold, I., Oral, E. A., Hegele, R. A., Stroes, E. S. G., Witztum, J. L., & Tsimikas, S.
Affiliations
  • Ionis Pharmaceuticals (United States) (US)
  • Ionis Pharmaceuticals, Carlsbad, CA
  • University of Cologne, Cologne, Germany
  • University of Michigan (US)
  • Western University (CA)
  • Amsterdam UMC Location University of Amsterdam (NL)
  • University of California San Diego (US)
Venue
New England Journal of Medicine
Published
2024-02
Volume
390
Issue
5
Pages
476-477
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W4391378948
Cited by
85
References
4
Citations by year
2026: 23 · 2025: 39 · 2024: 23
FWCI
35.79
Type
journal article
Language
en
Open access
closed
Locations
  • New England Journal of Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (submittedVersion)
Funders
Ionis Pharmaceuticals
Topics
  • Health Sciences › Medicine › Surgery › Pancreatitis Pathology and Treatment
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
  • Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
Keywords
volanesorsen, acute pancreatitis, hypertriglyceridemia, triglyceride-lowering therapy, apolipoprotein C-III, triglyceride-rich lipoproteins
MeSH terms
Acute Disease, Humans, Hyperlipidemias, Oligonucleotides, Pancreatitis, Triglycerides, Hypertriglyceridemia

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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