Amplifying RNA Vaccine Development

Direct Gene Transfer into Mouse Muscle in Vivo

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Self-amplifying RNA vaccines give equivalent protection against influenza to mRNA vaccines but at much lower doses

Vogel, A. B., Lambert, L., Kinnear, E., Busse, D., Erbar, S., Reuter, K. C., Wicke, L., Perkovic, M., Beissert, T., Haas, H., et al. (2018) · Molecular Therapy · doi:10.1016/j.ymthe.2017.11.017 · Cited by 501 · see citing works

Enhancing immune responses using suicidal DNA vaccines

Berglund, P., Smerdou, C., Fleeton, M. N., Tubulekas, L., & Liljeström, P. (1998) · Nature Biotechnology · doi:10.1038/nbt0698-562 · Cited by 229 · see citing works

A trans-amplifying RNA vaccine strategy for induction of potent protective immunity

Beissert, T., Perkovic, M., Vogel, A., Erbar, S., Walzer, K. C., Hempel, T., Brill, S., Haefner, E., Becker, R., Türeci, Ö., et al. (2020) · Molecular Therapy · doi:10.1016/j.ymthe.2019.09.009 · Cited by 212 · see citing works

Generation of cytotoxic and humoral immune responses by nonreplicative recombinant Semliki Forest virus.

Zhou, X., Berglund, P., Zhao, H., Liljeström, P., & Jondal, M. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.7.3009 · Cited by 115 · see citing works

Unlocking the promise of mRNA therapeutics

Rohner, E., Yang, R., Foo, K. S., Goedel, A., & Chien, K. R. (2022) · Nature Biotechnology · doi:10.1038/s41587-022-01491-z · Cited by 612 · see citing works

Advances in COVID-19 mRNA vaccine development

Fang, E., Liu, X., Li, M., Zhang, Z., Song, L., Zhu, B., Wu, X., Liu, J., Zhao, D., & Li, Y. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-00950-y · Cited by 601 · see citing works

Age-dependent Immune Response to the Biontech/Pfizer BNT162b2 Coronavirus Disease 2019 Vaccination

Müller, L., Andrée, M., Moskorz, W., Drexler, I., Walotka, L., Grothmann, R., Ptok, J., Hillebrandt, J., Ritchie, A., Rabl, D., et al. (2021) · Clinical Infectious Diseases · doi:10.1093/cid/ciab381 · Cited by 511 · see citing works

Innate immune mechanisms of mRNA vaccines

Verbeke, R., Hogan, M. J., Loré, K., & Pardi, N. (2022) · Immunity · doi:10.1016/j.immuni.2022.10.014 · Cited by 518 · see citing works

The dawn of mRNA vaccines: the COVID-19 case

Verbeke, R., Lentacker, I., De Smedt, S. C., & Dewitte, H. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.03.043 · Cited by 504 · see citing works

mRNA-based cancer therapeutics

Liu, C., Shi, Q., Huang, X., Koo, S., Kong, N., & Tao, W. (2023) · Nature Reviews Cancer · doi:10.1038/s41568-023-00586-2 · Cited by 500 · see citing works

Lipid nanoparticles for delivery of RNA therapeutics: Current status and the role of <i>in vivo</i> imaging

Jung, H. N., Lee, S.-Y., Lee, S., Youn, H., & Im, H.-J. (2022) · Theranostics · doi:10.7150/thno.77259 · Cited by 282 · see citing works

COVID-19: Coronavirus Vaccine Development Updates

Zhao, J., Zhao, S., Ou, J., Zhang, J., Lan, W., Guan, W., Wu, X., Yan, Y., Zhao, W., Wu, J., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.602256 · Cited by 225 · see citing works

A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice

de Alwis, R., Gan, E. S., Chen, S., Leong, Y. S., Tan, H. C., Zhang, S. L., Yau, C., Low, J. G. H., Kalimuddin, S., Matsuda, D., et al. (2021) · Molecular Therapy · doi:10.1016/j.ymthe.2021.04.001 · Cited by 191 · see citing works

A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies

Kumari, M., Lu, R., Li, M., Huang, J., Hsu, F., Ko, S.-H., Ke, F.-Y., Su, S.-C., Liang, K.-H., Yuan, J. P., et al. (2022) · Journal of Biomedical Science · doi:10.1186/s12929-022-00852-9 · Cited by 157 · see citing works

The Covid-19 Vaccine-Development Multiverse

Heaton, P. M. (2020) · New England Journal of Medicine · doi:10.1056/nejme2025111 · Cited by 151 · see citing works

Clinical approval of nanotechnology-based SARS-CoV-2 mRNA vaccines: impact on translational nanomedicine

Milane, L. S., & Amiji, M. M. (2021) · Drug Delivery and Translational Research · doi:10.1007/s13346-021-00911-y · Cited by 116 · see citing works

From COVID-19 to Cancer mRNA Vaccines: Moving From Bench to Clinic in the Vaccine Landscape

Chakraborty, C., Sharma, A. R., Bhattacharya, M., & Lee, S. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.679344 · Cited by 111 · see citing works

Lipid-Based Nanoformulations for Drug Delivery: An Ongoing Perspective

Rehman, M., Tahir, N., Sohail, M. F., Qadri, M. U., Duarte, S. O. D., Brandão, P., Esteves, T., Javed, I., & Fonte, P. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16111376 · Cited by 104 · see citing works

Recent developments of RNA-based vaccines in cancer immunotherapy

Faghfuri, E., Pourfarzi, F., Faghfouri, A. H., Shadbad, M. A., Hajiasgharzadeh, K., & Baradaran, B. (2020) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2020.1815704 · Cited by 99 · see citing works

Approved and marketed nanoparticles for disease targeting and applications in COVID-19

Abdellatif, A. A. H., & Alsowinea, A. F. (2021) · Nanotechnology Reviews · doi:10.1515/ntrev-2021-0115 · Cited by 101 · see citing works

Advancements of in vitro transcribed mRNA (IVT mRNA) to enable translation into the clinics

Kang, D. D., Li, H., & Dong, Y. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.114961 · Cited by 100 · see citing works

Progress and Pitfalls in the Quest for Effective SARS-CoV-2 (COVID-19) Vaccines

Flanagan, K. L., Best, E., Crawford, N. W., Giles, M., Koirala, A., Macartney, K. K., Russell, F. M., Teh, B. W., & Wen, S. C.-H. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.579250 · Cited by 95 · see citing works

Strategies for Vaccination: Conventional Vaccine Approaches Versus New-Generation Strategies in Combination with Adjuvants

Bouazzaoui, A., Abdellatif, A. A. H., Al-Allaf, F. A., Bogari, N. M., Al-Dehlawi, S., & Qari, S. H. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13020140 · Cited by 91 · see citing works

mRNA Vaccine Development for Emerging Animal and Zoonotic Diseases

Le, T., Sun, C., Chang, J., Zhang, G., & Yin, X. (2022) · Viruses · doi:10.3390/v14020401 · Cited by 93 · see citing works

Combining Cancer Vaccines with Immunotherapy: Establishing a New Immunological Approach

Kim, C.-G., Sang, Y. B., Lee, J. H., & Chon, H. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158035 · Cited by 77 · see citing works

Self-Amplifying RNA Vaccine Candidates: Alternative Platforms for mRNA Vaccine Development

Schmidt, C., & Schnierle, B. S. (2023) · Pathogens · doi:10.3390/pathogens12010138 · Cited by 78 · see citing works

Self-Amplifying RNA Approach for Protein Replacement Therapy

Papukashvili, D., Rcheulishvili, N., Liu, C., Ji, Y., He, Y., & Wang, P. G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232112884 · Cited by 76 · see citing works

Perspectives on RNA Vaccine Candidates for COVID-19

Borah, P., Deb, P. K., Al‐Shar’i, N. A., Dahabiyeh, L. A., Venugopala, K. N., Singh, V., Shinu, P., Hussain, S., Deka, S., Chandrasekaran, B., et al. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.635245 · Cited by 66 · see citing works

mRNA therapies: Pioneering a new era in rare genetic disease treatment

Shen, G., Liu, J., Yang, H., Xie, N., & Yang, Y. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.03.056 · Cited by 61 · see citing works

SARS-CoV-2: Targeted managements and vaccine development

Bakhiet, M., & Taurin, S. (2020) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2020.11.001 · Cited by 59 · see citing works

Is there a role for childhood vaccination against COVID‐19?

Eberhardt, C. S., & Siegrist, C. (2020) · Pediatric Allergy and Immunology · doi:10.1111/pai.13401 · Cited by 56 · see citing works

Self-amplifying mRNA vaccines: Mode of action, design, development and optimization

Pourseif, M. M., Masoudi‐Sobhanzadeh, Y., Azari, E., Parvizpour, S., Barar, J., Ansari, R. A., & Omidi, Y. (2022) · Drug Discovery Today · doi:10.1016/j.drudis.2022.103341 · Cited by 54 · see citing works

Long-term survival of patients with stage III colon cancer treated with VRP-CEA(6D), an alphavirus vector that increases the CD8+ effector memory T cell to Treg ratio

Crosby, E. J., Hobeika, A. C., Niedzwiecki, D., Rushing, C. N., Hsu, D. S., Berglund, P., Smith, J., Osada, T., Gwin, W. R., Hartman, Z. C., et al. (2020) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2020-001662 · Cited by 54 · see citing works

The Importance of RNA-Based Vaccines in the Fight against COVID-19: An Overview

Machado, B. A. S., Hodel, K. V. S., Fonseca, L. M. D. S., Mascarenhas, L. A. B., Andrade, L. P. C. D. S., Rocha, V. P. C., Soares, M. B. P., Berglund, P., Duthie, M. S., Reed, S. G., et al. (2021) · Vaccines · doi:10.3390/vaccines9111345 · Cited by 52 · see citing works

Modulating intracellular pathways to improve non-viral delivery of RNA therapeutics

de Vyver, T. V., Smedt, S. C. D., & Raemdonck, K. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.114041 · Cited by 51 · see citing works

Cellular Trafficking of Nanotechnology‐Mediated mRNA Delivery

Huang, P., Deng, H., Wang, C., Zhou, Y., & Chen, X. S. (2023) · Advanced Materials · doi:10.1002/adma.202307822 · Cited by 49 · see citing works

mRNA Vaccines: Why Is the Biology of Retroposition Ignored?

Domazet‐Lošo, T. (2022) · Genes · doi:10.3390/genes13050719 · Cited by 44 · see citing works

Advancements and challenges in mRNA and ribonucleoprotein-based therapies: From delivery systems to clinical applications

Eftekhari, Z., Zohrabi, H., Oghalaie, A., Ebrahimi, T., Shariati, F. S., Behdani, M., & Kazemi‐Lomedasht, F. (2024) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2024.102313 · Cited by 43 · see citing works

Therapeutic synthetic and natural materials for immunoengineering

Slezak, A., Chang, K., Hossainy, S., Mansurov, A., Rowan, S. J., Hubbell, J. A., & Guler, M. O. (2024) · Chemical Society Reviews · doi:10.1039/d3cs00805c · Cited by 44 · see citing works

A trans-amplifying RNA simplified to essential elements is highly replicative and robustly immunogenic in mice

Perković, M., Gawletta, S., Hempel, T., Brill, S., Nett, E., Şahin, U., & Beißert, T. (2023) · Molecular Therapy · doi:10.1016/j.ymthe.2023.01.019 · Cited by 46 · see citing works

In Vitro Transcribed RNA-Based Platform Vaccines: Past, Present, and Future

Perenkov, A. D., Sergeeva, A. D., Vedunova, M. V., & Krysko, D. V. (2023) · Vaccines · doi:10.3390/vaccines11101600 · Cited by 40 · see citing works

Together is Better: mRNA Co‐Encapsulation in Lipoplexes is Required to Obtain Ratiometric Co‐Delivery and Protein Expression on the Single Cell Level

Zhang, H., Bussmann, J., Huhnke, F. H., Devoldere, J., Minnaert, A., Jiskoot, W., Serwane, F., Spatz, J. P., Röding, M., Smedt, S. C. D., et al. (2021) · Advanced Science · doi:10.1002/advs.202102072 · Cited by 37 · see citing works

Cancer vaccine strategies using self-replicating RNA viral platforms

Dailey, G. P., Crosby, E. J., & Hartman, Z. C. (2022) · Cancer Gene Therapy · doi:10.1038/s41417-022-00499-6 · Cited by 36 · see citing works

Peroxisomes exhibit compromised structure and matrix protein content in SARS-CoV-2-infected cells

Knoblach, B., Ishida, R., Hobman, T. C., & Rachubinski, R. A. (2021) · Molecular Biology of the Cell · doi:10.1091/mbc.e21-02-0074 · Cited by 36 · see citing works

Engineering DNA Nanostructures to Manipulate Immune Receptor Signaling and Immune Cell Fates

Tseng, C., Wang, W. X., Douglas, T. R., & Chou, L. Y. T. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202101844 · Cited by 36 · see citing works

Virus-like Magnetic Mesoporous Silica Particles as a Universal Vaccination Platform against Pathogenic Infections

Liu, M., Zhao, Y. G., Shi, Z., Zink, J. I., & Yu, Q. (2023) · ACS Nano · doi:10.1021/acsnano.3c00644 · Cited by 29 · see citing works

Re-thinking yellow fever vaccines: fighting old foes with new generation vaccines

Zurbia-Flores, G. M., Rollier, C. S., & Reyes‐Sandoval, A. (2021) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2021.1895644 · Cited by 28 · see citing works

Immunotherapy for HER-2 positive breast cancer

Yang, T., Kang, L., Li, D., & Song, Y. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1097983 · Cited by 27 · see citing works

Ongoing Clinical Trials of Vaccines to Fight against COVID-19 Pandemic

Chakraborty, C., Sharma, A. R., Bhattacharya, M., Sharma, G., Saha, R. P., & Lee, S. (2021) · Immune Network · doi:10.4110/in.2021.21.e5 · Cited by 25 · see citing works

RNA-based therapies in liver metabolic diseases

Fontanellas, A., Berraondo, P., Urigo, F., Jericó, D., Martini, P. G. V., Pastor, F., & Avila, M. A. (2025) · Gut · doi:10.1136/gutjnl-2023-331742 · Cited by 23 · see citing works

Chemically modified mRNA beyond COVID-19: Potential preventive and therapeutic applications for targeting chronic diseases

Elkhalifa, D. H., Rayan, M., Negmeldin, A. T., Elhissi, A. M. A., & Khalil, A. A. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112385 · Cited by 23 · see citing works

Biosecurity risks associated with vaccine platform technologies

Sandbrink, J. B., & Koblentz, G. D. (2021) · Vaccine · doi:10.1016/j.vaccine.2021.02.023 · Cited by 22 · see citing works

Immune gene expression analysis indicates the potential of a self-amplifying Covid-19 mRNA vaccine

Ong, E. Z., Yee, J. X., Ooi, J. S. G., Syenina, A., de Alwis, R., Chen, S., Sim, J. X. Y., Kalimuddin, S., Leong, Y. S., Chan, Y. F. Z., et al. (2022) · npj Vaccines · doi:10.1038/s41541-022-00573-y · Cited by 20 · see citing works

Efforts towards a COVID ‐19 vaccine

Brüssow, H. (2020) · Environmental Microbiology · doi:10.1111/1462-2920.15225 · Cited by 19 · see citing works

Tipping the scales: Immunotherapeutic strategies that disrupt immunosuppression and promote immune activation

Santiago-Sánchez, G. S., Hodge, J. W., & Fabian, K. P. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.993624 · Cited by 19 · see citing works

Discovery and development of COVID ‐19 vaccine from laboratory to clinic

Saravanan, V., Chagaleti, B. K., Narayanan, P. L., Anandan, V. B., Manoharan, H., Anjana, G. V., Peraman, R., Namasivayam, S. K. R., Kavisri, M., Arockiaraj, J., et al. (2023) · Chemical Biology & Drug Design · doi:10.1111/cbdd.14383 · Cited by 18 · see citing works

Combination Organelle Mitochondrial Endoplasmic Reticulum Therapy (COMET) for Multidrug Resistant Breast Cancer

Milane, L. S., Dolare, S., Ren, G., & Amiji, M. M. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.09.023 · Cited by 17 · see citing works

Injection site vaccinology of a recombinant vaccinia-based vector reveals diverse innate immune signatures

Hazlewood, J. E., Dumenil, T. D., Le, T. T., Slonchak, A., Kazakoff, S. H., Patch, A., Gray, L.-A., Howley, P. M., Liu, L., Hayball, J. D., et al. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1009215 · Cited by 16 · see citing works

Preparation of RNAs with non-canonical 5′ ends using novel di- and trinucleotide reagents for co-transcriptional capping

Depaix, A., Grudzien‐Nogalska, E., Fedorczyk, B., Kiledjian, M., Jemielity, J., & Kowalska, J. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.854170 · Cited by 15 · see citing works

RNA Engineering for Public Health: Innovations in RNA-Based Diagnostics and Therapeutics

Thavarajah, W., Hertz, L. M., Bushhouse, D. Z., Archuleta, C. M., & Lucks, J. B. (2021) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-101420-014055 · Cited by 15 · see citing works

The oral vaccine based on self-replicating RNA lipid nanoparticles can simultaneously neutralize both SARS-CoV-2 variants alpha and delta

Mohammadi, G., Koranni, Z. S., & Jebali, A. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.108231 · Cited by 15 · see citing works

Quantitative evaluation of PpSP15-LmSTI1 fusion gene expression following transfection with an alphavirus-derived self-amplifying mRNA and conventional DNA vaccine platforms

Savar, N. S., Vallet, T., Azizi, M., Arashkia, A., Lundstrom, K. H., Vignuzzi, M., & Niknam, H. M. (2021) · Molecular and Cellular Probes · doi:10.1016/j.mcp.2021.101749 · Cited by 15 · see citing works

Will the mRNA vaccine platform be the panacea for the development of vaccines against antimicrobial resistant (AMR) pathogens?

Chen, W. (2021) · Expert Review of Vaccines · doi:10.1080/14760584.2022.2011226 · Cited by 14 · see citing works

Essential considerations during vaccine design against COVID-19 and review of pioneering vaccine candidate platforms

Bayat, M., Asemani, Y., & Najafi, S. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.107679 · Cited by 14 · see citing works

RNAglib: a python package for RNA 2.5 D graphs

Mallet, V., Oliver, C., Broadbent, J., Hamilton, W. L., & Waldispühl, J. (2021) · Bioinformatics · doi:10.1093/bioinformatics/btab844 · Cited by 13 · see citing works

What rheumatologists need to know about mRNA vaccines: current status and future of mRNA vaccines in autoimmune inflammatory rheumatic diseases

Park, J. K., Lee, E. B., & Winthrop, K. L. (2024) · Annals of the Rheumatic Diseases · doi:10.1136/ard-2024-225492 · Cited by 11 · see citing works

Impact of Ribosome Activity on SARS-CoV-2 LNP – Based mRNA Vaccines

Tsiambas, E., Chrysovergis, A., PAPANIKOLAOU, V. S., MASTRONIKOLIS, N. S., Ragos, V., Batistatou, A. K., Peschos, D., Kavantzas, N., Lazaris, A. C., & Kyrodimos, E. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.654866 · Cited by 11 · see citing works

The dynamics of quantitative SARS‐CoV‐2 antispike IgG response to BNT162b2 vaccination

Kaneko, S., Kurosaki, M., Sugiyama, T., Takahashi, Y., Yamaguchi, Y., Nagasawa, M., & Izumi, N. (2021) · Journal of Medical Virology · doi:10.1002/jmv.27231 · Cited by 10 · see citing works

Multimeric RNAs for efficient RNA-based therapeutics and vaccines

Kim, D., Han, S. W., Ji, Y., Moon, S., Nam, H., & Lee, J. B. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.03.052 · Cited by 11 · see citing works

RNA Vaccines against Infectious Diseases: Vital Progress with Room for Improvement

Abdelzaher, H. M., Gabr, A. S., Saleh, B. M., Gawad, R. M. A., Nour, A. A., & Abdelnaser, A. (2021) · Vaccines · doi:10.3390/vaccines9111211 · Cited by 12 · see citing works

The mRNA-Based Innovative Strategy: Progress and Challenges

Zhou, H., Wei, D., Chen, Z., Chen, H., Dong, C., Cai, W., Wang, J., Liu, X., Li, Y., Yang, Y., et al. (2026) · Nano-Micro Letters · doi:10.1007/s40820-025-01906-x · Cited by 14 · see citing works

Sodium and Magnesium Ion Location at the Backbone and at the Nucleobase of RNA: Ab Initio Molecular Dynamics in Water Solution

Kolev, S. K., Petkov, P. S., Milenov, T. I., & Vayssilov, G. N. (2022) · ACS Omega · doi:10.1021/acsomega.2c01327 · Cited by 10 · see citing works

Intratumoral immunotherapy with mRNAs encoding chimeric protein constructs encompassing IL-12, CD137 agonists, and TGF-β antagonists

Cirella, A., Bolaños, E., Luri‐Rey, C., Trani, C. A. D., Olivera, I., Gomis, G., Glez‐Vaz, J., Pinci, B., Garasa, S., Sánchez‐Gregorio, S., et al. (2023) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2023.07.026 · Cited by 10 · see citing works

Progress Towards a Therapeutic HIV DNA Vaccine

Munson, P. V. (2022) · Expert Review of Vaccines · doi:10.1080/14760584.2022.2059467 · Cited by 10 · see citing works

Replicon RNA vaccines: design, delivery, and immunogenicity in infectious diseases and cancer

Tang, L., Que, H., Wei, Y., Yang, T., Tong, A., & Wei, X. (2025) · Journal of Hematology & Oncology · doi:10.1186/s13045-025-01694-2 · Cited by 10 · see citing works

Towards mRNA therapeutics 2.0

Chien, K. R., Foo, K. S., & Witman, N. (2026) · Nature Reviews Drug Discovery · doi:10.1038/s41573-026-01459-7 · Cited by 10 · see citing works

Do RNA vaccines obviate the need for genotoxicity studies?

Cimolai, N. (2020) · Mutagenesis · doi:10.1093/mutage/geaa028 · Cited by 8 · see citing works

Unleashing the potential of mRNA : Overcoming delivery challenges with nanoparticles

Chen, Q., Huo, K.-G., Ji, S., Pang, S., Sun, T., Niu, Y., Jiang, Z., Zhang, P., Han, S., & Li, J. (2024) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10713 · Cited by 7 · see citing works

Recent Progress of Paclitaxel Delivery Systems: Covalent and Noncovalent Approaches

Wang, J., Li, X., Wu, W., Xu, X., Xu, H., & Zhang, T. (2023) · Advanced Therapeutics · doi:10.1002/adtp.202200281 · Cited by 7 · see citing works

COVID-19 vaccines: current and future challenges

Mohammadi, D., Ghasemi, M., Manouchehrian, N., Zafarmand, M., Akbari, M., & Boroumand, A. B. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1434181 · Cited by 6 · see citing works

A second-generation, self-amplifying COVID-19 Vaccine: World’s first approval and distribution in the Japanese market with vaccine hesitancy

Naito, T. (2025) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2025.2530291 · Cited by 6 · see citing works

Trans amplifying mRNA vaccine expressing consensus spike elicits broad neutralization of SARS CoV 2 variants

Gontu, A., Misra, S., Chothe, S. K., Ramasamy, S., Jakka, P., Byukusenge, M., LaBella, L. C., Nair, M. S., Jayarao, B. M., Archetti, M., et al. (2025) · npj Vaccines · doi:10.1038/s41541-025-01166-1 · Cited by 6 · see citing works

Lipid nanoparticle-assisted mRNA therapy for cancer treatment

Kim, H.-J., Le, N. D., Oh, H.-J., Kim, B., Yoo, E., Kim, J., & Yim, H. (2025) · Applied Physics Reviews · doi:10.1063/5.0247029 · Cited by 5 · see citing works

Modern vaccine strategies for emerging zoonotic viruses

Ahmed, A., Safdar, M., Sardar, S., Yousaf, S., Farooq, F., Raza, A., Shahid, M., Malik, K. A., & Afzal, S. (2022) · Expert Review of Vaccines · doi:10.1080/14760584.2022.2148660 · Cited by 6 · see citing works

Antiviral Drugs - in Past and Current Pandemics

Nandi, A., Das, A., Lin, W., & Chakraborty, P. (2023) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815080056123020009 · Cited by 4 · see citing works

Delivery of Rna Drugs: Beyond the Liver, More than Vaccine

Elnaggar, M. G., He, Y., & Yeo, Y. (2023) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2024.114203 · Cited by 4 · see citing works

A Computational Search for Peptide Vaccines Using Novel Mathematical Descriptors of Sequences of Emerging Pathogens

Chatterjee, S., Dey, S., Nandy, A., & Basak, S. C. (2020) · Topics in medicinal chemistry · doi:10.1007/7355_2020_108 · Cited by 4 · see citing works

An engineered linear cap-independent mRNA vaccine with intrinsic adjuvanticity induces potent anti-tumor immunity in mice

Yu, H., Yang, Y., Lin, P., Liu, C., Wen, Y., Huang, Z., Fang, Z., Hu, Z., & St, H. (2026) · Nature Communications · doi:10.1038/s41467-026-69972-2 · Cited by 3 · see citing works

In Vitro-Transcribed mRNAs as a New Generation of Therapeutics in the Dawn of Twenty-First Century: Exploitation of Peptides as Carriers for Their Intracellular Delivery

Miliotou, Α. N., Pappas, I. S., Vizirianakis, I. S., & Papadopoulou, L. C. (2022) · RNA technologies · doi:10.1007/978-3-031-08415-7_10 · Cited by 3 · see citing works

RNA Vaccines: The Evolution, Applications, and the Challenges Ahead

Banerji, I., Bhattacharjee, S., Mukherjee, K., & Bhattacharyya, S. N. (2023) · Springer eBooks · doi:10.1007/978-981-19-8520-1_10 · Cited by 3 · see citing works

Vaccine development strategies and impact

Nandi, A., Dey, Y. N., Maity, D., & Das, A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95374-0.00015-4 · Cited by 2 · see citing works

COVID-19: Do DNA / RNA vaccines integrate into the genome?

Pacheco, T. J. A., da Silva, V. C. M., de Souza, D. G., Borges, M. B. S., & Silva, S. A. E. (2021) · Research Society and Development · doi:10.33448/rsd-v10i1.12103 · Cited by 2 · see citing works

Nucleic acid therapy for metabolic-related diseases

Guo, J. R., Lü, Z., Zhao, R., Li, B.-K., & Zhang, X. (2024) · Chinese Chemical Letters · doi:10.1016/j.cclet.2024.109875 · Cited by 2 · see citing works

Next Generation Vaccines

Kebabçıoğlu, C., Erganiş, O., & Tawor, A. B. (2024) · Dicle Üniversitesi Veteriner Fakültesi Dergisi · doi:10.47027/duvetfd.1474558 · Cited by 1 · see citing works

A novel replicase-mediated self-amplifying RNA amplification mechanism of the SARS-CoV-2 replication–transcription system

Liu, H.-L., Lin, S., Hung, W., Chang, D. C., & Lin, S.-L. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.151654 · Cited by 1 · see citing works

Pharmaceutical perspectives on oligonucleotide therapeutics and delivery systems

Staller, D. W., Gawargi, F. I., Panigrahi, S. S., Mishra, P. K., & Mahato, R. I. (2025) · Pharmacological Reviews · doi:10.1016/j.pharmr.2025.100065 · Cited by 1 · see citing works

International legal regulation of the circulation of dual-use biotechnologies

Абашидзе, А., & Маличенко, В. С. (2023) · Вестник Российского университета дружбы народов. Серия: Юридические науки · doi:10.22363/2313-2337-2023-27-3-541-563 · Cited by 1 · see citing works

Comparative Function Analysis of Self‐Amplifying mRNA and Self‐Amplifying DNA

Li, W., Wang, Y., Wang, C., Huo, Y., & Lu, Y. (2025) · ChemBioChem · doi:10.1002/cbic.202500110 · Cited by 1 · see citing works

Potential Therapeutics Pathways in Solving the Challenges of the COVID-19 Pandemic

Mafugu, T. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.96283 · Cited by 1 · see citing works

Nucleic acid-based vaccines of COVID-19 and their delivery systems

Yang, H., Zhang, M., Weng, Y., Cao, Y., & Huang, Y. (2021) · Scientia Sinica Vitae · doi:10.1360/ssv-2021-0051 · Cited by 1 · see citing works

COVID-19 as milestone for the use of new vaccine types

Marković, M. (2020) · Hrana i ishrana · doi:10.5937/hraish2001001m · Cited by 1 · see citing works

A New Era in Antigen-Specific Immunotherapy: The Promise of Nucleoside-Modified mRNA Vaccines for Autoimmune Thyroid Disease

Banga, J. P., & Stan, M. N. (2021) · Clinical Thyroidology · doi:10.1089/ct.2021;33.154-156

Development of leading first-generation vaccines against SARS-CoV-2

Perera, P., & Perera, L. (2021) · Microbes and infection · doi:10.1016/j.micinf.2021.104841

Genomic Evidence Provides the Understanding of SARS-CoV-2 Composition, Divergence, and Diagnosis

Tiwari, M., Suri, G. S., Kaur, G., Singh, B. P., Mehta, S., & Mishra, D. (2021) · Springer eBooks · doi:10.1007/978-981-16-0691-5_4

RNA Vaccines: Methods and Protocols

Kramps, T., & Elbers, K. (2017) · Cited by 16 · see citing works

RNA Vaccines for COVID-19

Lin, C.-J., Mecham, R. P., & Mann, D. L. (2020) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2020.11.006 · Cited by 10 · see citing works

Self-Amplifying RNA Vaccine Candidates: Alternative Platforms for mRNA Vaccine Development

Schmidt, C., & Schnierle, B. S. (2023) · Pathogens · doi:10.3390/pathogens12010138 · Cited by 78 · see citing works

RNA as a base for novel methods of immunotherapy and immune

Popov, D. (2021) · doi:10.13140/rg.2.2.16377.80482

RNA Vaccines

Kramps, T. (2024) · Methods in molecular biology · doi:10.1007/978-1-0716-3770-8 · Cited by 2 · see citing works