Enhancing immune responses using suicidal DNA vaccines

Direct Gene Transfer into Mouse Muscle in Vivo

Wolff, J. A., Malone, R. W., Williams, P., Chong, W., Acsadi, G., Jani, A., & Felgner, P. L. (1990) · Science · doi:10.1126/science.1690918 · Cited by 4,173 · see citing works

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

Ulmer, J. B., Donnelly, J., Parker, S. E., Rhodes, G. H., Felgner, P. L., Dwarki, V., Gromkowski, S. H., Deck, R. R., DeWitt, C. M., Friedman, A., et al. (1993) · Science · doi:10.1126/science.8456302 · Cited by 2,318 · see citing works

Genetic immunization is a simple method for eliciting an immune response

Tang, D.-C. C., DeVit, M. J., & Johnston, S. A. (1992) · Nature · doi:10.1038/356152a0 · Cited by 1,504 · see citing works

Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.

Taswell, C. (1981) · The Journal of Immunology · doi:10.4049/jimmunol.126.4.1614 · Cited by 1,249 · see citing works

DNA VACCINES

Donnelly, J., Ulmer, J. B., Shiver, J. W., & Liu, M. A. (1997) · Annual Review of Immunology · doi:10.1146/annurev.immunol.15.1.617 · Cited by 985 · see citing works

A New Generation of Animal Cell Expression Vectors Based on the Semliki Forest Virus Replicon

Liljeström, P., & Garoff, H. (1991) · Nature Biotechnology · doi:10.1038/nbt1291-1356 · Cited by 905 · see citing works

Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells

Rötzschke, O., Falk, K., Deres, K., Schild, H., Norda, M., Metzger, J. W., Jung, G., & Rammensee, H. (1990) · Nature · doi:10.1038/348252a0 · Cited by 771 · see citing works

Long-term persistence of plasmid DNA and foreign gone expression in mouse muscle

Wolff, J. A., Ludtke, J. J., Acsádi, G., Williams, P. M., & Jáni, Á. (1992) · Human Molecular Genetics · doi:10.1093/hmg/1.6.363 · Cited by 739 · see citing works

Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses.

Raz, E., Carson, D. A., Parker, S. E., Parr, T. B., Abai, A. M., Aichinger, G., Gromkowski, S. H., Singh, M., Lew, D., & Yankauckas, M. A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.20.9519 · Cited by 543 · see citing works

Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene

Levine, B., Huang, Q. R., Isaacs, J. T., Reed, J. C., Griffin, D. E., & Hardwick, J. M. (1993) · Nature · doi:10.1038/361739a0 · Cited by 489 · see citing works

Replicon-Helper Systems from Attenuated Venezuelan Equine Encephalitis Virus: Expression of Heterologous Genesin Vitroand Immunization against Heterologous Pathogensin Vivo

Pushko, P., Parker, M., Ludwig, G. V., Davis, N., Johnston, R. E., & Smith, J. (1997) · Virology · doi:10.1006/viro.1997.8878 · Cited by 444 · see citing works

Gene Therapy by Intramuscular Injection of Plasmid DNA: Studies on Firefly Luciferase Gene Expression in Mice

Manthorpe, M., Cornefert-Jensen, F., Hartikka, J., Felgner, J. H., Rundell, A., Margalith, M., & Dwarki, V. (1993) · Human Gene Therapy · doi:10.1089/hum.1993.4.4-419 · Cited by 432 · see citing works

Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA

Robinson, H. L., Hunt, L., & Webster, R. G. (1993) · Vaccine · doi:10.1016/0264-410x(93)90385-b · Cited by 428 · see citing works

DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody

Davis, H. L., Michel, M., & Whalen, R. G. (1993) · Human Molecular Genetics · doi:10.1093/hmg/2.11.1847 · Cited by 401 · see citing works

Vaccination with a Plasmid Vector Carrying the Rabies Virus Glycoprotein Gene Induces Protective Immunity against Rabies Virus

Xiang, Z., Spitalnik, S. L., Tran, M., Wunner, W. H., Cheng, J., & Ertl, H. C. J. (1994) · Virology · doi:10.1006/viro.1994.1105 · Cited by 390 · see citing works

Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination

Letvin, N. L., Montefiori, D. C., Yasutomi, Y., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.17.9378 · Cited by 313 · see citing works

Semliki Forest Virus Expression System: Production of Conditionally Infectious Recombinant Particles

Berglund, P., Sjöberg, M., Garoff, H., Atkins, G. J., Sheahan, B. J., & Liljeström, P. (1993) · Nature Biotechnology · doi:10.1038/nbt0893-916 · Cited by 289 · see citing works

Potential DNA Vaccine Integration into Host Cell Genome

Nichols, W. W., Ledwith, B. J., Manam, S., & Troilo, P. J. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb44729.x · Cited by 268 · see citing works

The role of CpG dinucleotides in DNA vaccines

Krieg, A. Μ., Yi, A., Schorr, J., & Davis, H. L. (1998) · Trends in Microbiology · doi:10.1016/s0966-842x(97)01145-1 · Cited by 247 · see citing works

Levels of Peripheral T Cell Tolerance Induced by Different Doses of Tolerogen

Ferber, I., Schönrich, G., Schenkel, J., et al. (1994) · Science · doi:10.1126/science.8303275 · Cited by 230 · see citing works

Self-replicating Semliki Forest virus RNA as recombinant vaccine

Zhou, X., Berglund, P., Rhodes, G., Parker, S. E., Jondal, M., & Liljeström, P. (1994) · Vaccine · doi:10.1016/0264-410x(94)90074-4 · Cited by 193 · see citing works

Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer

Dubensky, T. W., Driver, D. A., Polo, J. M., Belli, B., LATHAM, E. M., Ibañez, C. E., Chada, S., Brumm, D., Banks, T. A., Mento, S. J., et al. (1996) · Journal of Virology · doi:10.1128/jvi.70.1.508-519.1996 · Cited by 192 · see citing works

DNA Immunization against Herpes Simplex Virus: Enhanced Efficacy Using a Sindbis Virus-Based Vector

Hariharan, M. J., Driver, D. A., Townsend, K., Brumm, D., Polo, J. M., Belli, B., Catton, D. J., Hsu, D. S., Mittelstaedt, D., McCormack, J. E., et al. (1998) · Journal of Virology · doi:10.1128/jvi.72.2.950-958.1998 · Cited by 178 · see citing works

Comparison of the effects of Sindbis virus and Sindbis virus replicons on host cell protein synthesis and cytopathogenicity in BHK cells

Frolov, I. V., & Schlesinger, S. (1994) · Journal of Virology · doi:10.1128/jvi.68.3.1721-1727.1994 · Cited by 147 · see citing works

DNA vaccines

Donnelly, J., Ulmer, J. B., & Liu, M. A. (1996) · Life Sciences · doi:10.1016/s0024-3205(96)00502-4 · Cited by 140 · see citing works

Protective cellular immunity: cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization

Fu, T., Friedman, A., Ulmer, J. B., et al. (1997) · Journal of Virology · doi:10.1128/jvi.71.4.2715-2721.1997 · Cited by 130 · see citing works

Induction of neonatal tolerance by plasmid DNA vaccination of mice.

Mor, G., Yamshchikov, G. V., Sedegah, M., Takeno, M., Wang, R., Houghten, R. A., Hoffman, S. L., & Klinman, D. M. (1996) · Journal of Clinical Investigation · doi:10.1172/jci119094 · Cited by 130 · see citing works

A Significantly Improved Semliki Forest Virus Expression System Based on Translation Enhancer Segments from the Viral Capsid Gene

Sjöberg, M., Suomalainen, M., & Garoff, H. (1994) · Nature Biotechnology · doi:10.1038/nbt1194-1127 · Cited by 130 · see citing works

Generation of cytotoxic and humoral immune responses by nonreplicative recombinant Semliki Forest virus.

Zhou, X., Berglund, P., Zhao, H., Liljeström, P., & Jondal, M. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.7.3009 · Cited by 115 · see citing works

A viral vaccine vector that expresses foreign genes in lymph nodes and protects against mucosal challenge

Davis, N., Brown, K. W., & Johnston, R. E. (1996) · Journal of Virology · doi:10.1128/jvi.70.6.3781-3787.1996 · Cited by 111 · see citing works

Protective CTL-dependent immunity and enhanced immunopathology in mice immunized by particle bombardment with DNA encoding an internal virion protein.

Zarozinski, C. C., Fynan, E. F., Selin, L. K., Robinson, H. L., & Welsh, R. M. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.154.8.4010 · Cited by 109 · see citing works

A Plasmid-Based Self-Amplifying Sindbis Virus Vector

Herweijer, H., Latendresse, J. S., Williams, P., Zhang, G., Dankó, I., Schlesinger, S., & Wolff, J. A. (1995) · Human Gene Therapy · doi:10.1089/hum.1995.6.9-1161 · Cited by 95 · see citing works

Death mechanisms in cultured cells infected by Semliki Forest virus.

Glasgow, G. M., Atkins, G. J., Gee, M. M. M., et al. (1997) · Journal of General Virology · doi:10.1099/0022-1317-78-7-1559 · Cited by 92 · see citing works

RAMPAGE: Promoter Activity Profiling by Paired-End Sequencing of 5′-Complete cDNAs

Batut, P. J., & Gingeras, T. (2013) · Current Protocols in Molecular Biology · doi:10.1002/0471142727.mb25b11s104 · Cited by 79 · see citing works

Alphavirus expression vectors and their use as recombinant vaccines: a minireview

Tubulekas, I., Berglund, P., Fleeton, M. N., & Liljeström, P. (1997) · Gene · doi:10.1016/s0378-1119(96)00679-8 · Cited by 67 · see citing works

Expression of Proteins Using Semliki Forest Virus Vectors

Liljeström, P., & Garoff, H. (1995) · Current Protocols in Molecular Biology · doi:10.1002/0471142727.mb1620s29 · Cited by 55 · see citing works

Long life span of tolerant T cells and the role of antigen in maintenance of peripheral tolerance

Alferink, J., Schittek, B., Schönrich, G., et al. (1995) · International Immunology · doi:10.1093/intimm/7.2.331 · Cited by 53 · see citing works

The pathogenicity of the M9 mutant of Semliki Forest virus in immune-compromised mice.

Gates, M., Sheahan, B., & Atkins, G. (1984) · Journal of General Virology · doi:10.1099/0022-1317-65-1-73 · Cited by 39 · see citing works

Neurogenic spread of Semliki forest virus in mice

Kaluza, G., Lell, G., Reinacher, M., et al. (1987) · Archives of Virology · doi:10.1007/bf01313896 · Cited by 31 · see citing works

Cloning of human IL-12 p40 and p35 DNA into the Semliki Forest virus vector: expression of IL-12 in human tumor cells

Zhang, J., Asselin‐Paturel, C., Bex, F., et al. (1997) · Gene Therapy · doi:10.1038/sj.gt.3300409 · Cited by 31 · see citing works

Long-term effects of Semliki Forest virus infection in the mouse central nervous system.

Donnelly, S., Sheahan, B. J., & Atkins, G. J. (1997) · PubMed · Cited by 29 · see citing works

Long‐term effects of Semliki Forest virus infection in the mouse central nervous system

Donnelly, S., Sheahan, B. J., & Atkins, G. J. (1997) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1997.tb01207.x · Cited by 24 · see citing works

Expression of IFN A genes in subpopulations of peripheral blood cells

Brandt, E. R., Linnane, A. W., & Devenish, R. J. (1994) · British Journal of Haematology · doi:10.1111/j.1365-2141.1994.tb04820.x · Cited by 23 · see citing works

DNA Vaccines

Robinson, H. L., LU, S., Feltquate, D., et al. (1996) · AIDS Research and Human Retroviruses · doi:10.1089/aid.1996.12.455 · Cited by 19 · see citing works

An <i>Alphavirus</i> -derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

Erasmus, J. H., Khandhar, A. P., O’Connor, M. A., Walls, A. C., Hemann, E. A., Murapa, P., Archer, J., Leventhal, S., Fuller, J. T., Lewis, T. B., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.abc9396 · Cited by 241 · see citing works

Alphavirus vectors and vaccination

Rayner, J. O., Dryga, S. A., & Kamrud, K. I. (2002) · Reviews in Medical Virology · doi:10.1002/rmv.360 · Cited by 181 · see citing works

Self-replicative RNA vaccines elicit protection against influenza A virus, respiratory syncytial virus, and a tickborne encephalitis virus

Fleeton, M. N., Chen, M., Berglund, P., Rhodes, G., Parker, S. E., Murphy, M., Atkins, G. J., & Liljeström, P. (2001) · The Journal of Infectious Diseases · doi:10.1086/319857 · Cited by 157 · see citing works

Amplifying RNA Vaccine Development

Fuller, D. H., & Berglund, P. (2020) · New England Journal of Medicine · doi:10.1056/nejmcibr2009737 · Cited by 116 · see citing works

Intradermal Electroporation of Naked Replicon RNA Elicits Strong Immune Responses

Johansson, D. X., Ljungberg, K., Kakoulidou, M., & Liljeström, P. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029732 · Cited by 98 · see citing works

Rise of the RNA machines – self-amplification in mRNA vaccine design

Comes, J. D. G., Pijlman, G. P., & Hick, T. A. H. (2023) · Trends in Biotechnology · doi:10.1016/j.tibtech.2023.05.007 · Cited by 87 · see citing works

Immunogenicity of a DNA-launched replicon-based canine parvovirus DNA vaccine expressing VP2 antigen in dogs

Dahiya, S. S., Saini, M., Kumar, P., & Gupta, P. K. (2012) · Research in Veterinary Science · doi:10.1016/j.rvsc.2012.01.017 · Cited by 12 · see citing works

Increased Immunogenicity of a DNA-Launched Venezuelan Equine Encephalitis Virus-Based Replicon DNA Vaccine

Ljungberg, K., Whitmore, A. C., Fluet, M. E., Moran, T. P., Shabman, R. S., Collier, M., Kraus, A., Thompson, J. M., Montefiori, D. C., Beard, C. W., et al. (2007) · Journal of Virology · doi:10.1128/jvi.01799-07 · Cited by 55 · see citing works

Application and development of viral vectors in neural stem cells

Li, L., Sun, C., Wang, X. B., et al. (2018) · Int J Genet · doi:10.3760/cma.j.issn.1673-4386.2018.06.013

Research Progress in Viral Vectors of Cancer Gene Therapy

Xiang-min, S. (2014) · Medical Recapitulate

Use of HIV as a gene transfer vector.

Pluta, K. D., & Kacprzak, M. M. (2009) · Acta Biochimica Polonica · doi:10.18388/abp.2009_2490 · Cited by 68 · see citing works