Leptin-Replacement Therapy for Lipodystrophy
Oral, Elif Arioglu, Simha, Vinaya, Ruiz, Elaine, Andewelt, Alexa, Premkumar, Ahalya, Snell, Peter, Wagner, Anthony J., DePaoli, Alex M. +4 more·2002·New England Journal of Medicine
Cited by (1,000)
Items 901–1,000 of 1,000
- Precision medicine: toward restoring fat with gene therapy in inherited lipodystrophyXavier Prieur, Lei Cao · 2024 · Gene Therapy
- Efficacy and Safety of Obeticholic Acid for Treating Hepatic Steatosis in Patients With Familial Partial LipodystrophyAbhimanyu Garg, Chandna Vasandani, Xilong Li, Claudia Quittner, Takeshi Yokoo · 2025 · The Journal of Clinical Endocrinology & Metabolism
- Regulación de la ingesta alimentaria: una perspectiva clínicaJavier Salvador, Gema Frühbeck · 2005 · Endocrinología y Nutrición
- Hipercrecimientos con y sin obesidad: fundamentos clínicos y molecularesJesús Argente, J.F. Sotos · 2011 · Anales de Pediatría
- Berardinelli Seip congenital lipodystrophy presenting with neonatal diabetes mellitus due to a mutation in the AGPAT2 geneV. Poovazhagi, S. Shanthi, S Jahnavi, Venkatesan Radha, Viswanathan Mohan · 2012 · International Journal of Diabetes in Developing Countries
- Effects of Leptin Receptor Gene 3'-untranslated Region Polymorphism on Metabolic Profiles in Young Japanese MenKanako Nishikai, Hiroshi Hirose, Tatsuya Ishii, Matsuhiko Hayashi, Ikuo Saito, Takao Saruta · 2004 · Journal of Atherosclerosis and Thrombosis
- How adipocytes integrate surplus caloric intake with caloric storage: lessons from Morgan Spurlock and some French geeseRoger H. Unger · 2004 · Current Opinion in Endocrinology & Diabetes
- So, Is Leptin Good or Bad in Chronic Kidney Disease?Kamyar Kalantar‐Zadeh · 2007 · Obesity
- Intra-abdominal adiposity, inflammation, and cardiovascular risk: New insight in the global cardiometabolic riskPaolo Calabrò, Edward T.H. Yeh · 2007 · Current Cardiovascular Risk Reports
- The Central Question of Type 2 DiabetesThaïs Rouquet, Marion S. Bonnet, Pierre Clément, Michel Dallaporta, Jean‐Denis Troadec, Julien Roux, Bruno Bariohay · 2013 · Pharmaceutical Patent Analyst
- A very rare cause of acute pancreatitis: Berardinelli-Seip congenital lipodystrophyAli İşlek, Ersin Sayar, Aygen Yılmaz, Özgür Duman, Reha Artan · 2014 · The Turkish Journal of Gastroenterology
- Weight-Loss DrugsGeorge A. Bray, Frank L. Greenway · 2007 · Humana Press eBooks
- Anti-obesity drugs currently used and new compounds in clinical developmentArmindo Martins · 2014 · World Journal of Meta-Analysis
- Congenital generalized lipodystrophy in a 4 year old Chinese girl.Guanping Dong, Li Liang, Chaochun Zou · 2005 · PubMed
- LeptinMartin Grosvenor Myers, Megan L. Greenwald-Yarnell · 2013 · Elsevier eBooks
- Lipodystrophy SyndromesChuanyun Gao, Christos Socrates Mantzoros · 2010 · Elsevier eBooks
- Pathophysiology of Diabetes in ObesityGeetha R. Soodini, Osama Hamdy · 2006 · Humana Press eBooks
- Editorial: Molecular Obesity Research: Lessons Learned?Rexford S. Ahima · 2014 · Molecular Endocrinology
- Evaluating the therapeutic impact of tirzepatide in people with partial lipodystrophyMandour Omer Mandour, Anna J. Stears, Agatha A. van der Klaauw, Catherine Flanagan, Lisa Gaff, Charlotte Jenkins, David B. Savage · 2026 · The Journal of Clinical Endocrinology & Metabolism
- Serum Leucine-Rich Alpha-2 Glycoprotein 1 Levels in Patients with Lipodystrophy SyndromesMichelle Krienke, Susan Kralisch, Leonie Wagner, Anke Tönjes, Konstanze Miehle · 2024 · Biomolecules
- Dose-finding and in vivo safety study of an adipose targeted leptin gene therapy for congenital leptin deficiencyWei Huang, Tawfiq Mohammed, Xunchang Zou, Anya A. Krishnan, Xiaokui Molly Mo, Min Xiao, Lei Cao · 2025 · Molecular Therapy — Methods & Clinical Development
- The clinical approach to child and adolescent patients with lipodystrophy: a series of international case discussionsRebecca J. Brown, Barış Akıncı, Saif Al-Yaarubi, Élise Bismuth, Marco Cappa, Asma Deeb, Clemens Kamrath, Carla Musso, Nivedita Patni, Flavia Prodam et al. · 2025 · Frontiers in Endocrinology
- LipodystrophieKonstanze Miehle, Michael Stümvoll, Mathias Faßhauer · 2011 · Der Internist
- Research Article Identification of differentially expressed genes in pathways of cerebral neurotransmission of anovulatory mice.M A Azevedo, I D C G Silva · 2017 · Genetics and Molecular Research
- Rabson Mendenhall Syndrome; a Case Report and Review of LiteratureDaniel Zamanfa, F Mohamadi, Somayeh Rostami Maskopaii · 2020 · International Journal of Environmental Chemistry
- Familial partial lipodystrophy type 2 and obesity, two adipose tissue pathologies with different inflammatory profilesGuillaume Treiber, Marie‐Paule Gonthier, Alice Guilleux, Samir Medjane, Oriane Bonfanti, Muriel Cogne, Olivier Meilhac, Estelle Nobécourt · 2023 · Diabetology & Metabolic Syndrome
- Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesityChandramohan Chitraju, Alexander W. Fischer, Yohannes Abere Ambaw, Kun Wang, Bo Yuan, Sheng Tony Hui, Tobias C. Walther, Robert V. Farese · 2023 · eLife
- Regulated regeneration of adipose tissue in lipodystrophic Agpat2-null mice partially ameliorates hepatic steatosisAnil K. Agarwal, Katie Tunison, Jay D. Horton, Abhimanyu Garg · 2024 · iScience
- Serum leptin changes with metformin treatment in polycystic ovarian syndromeHafsa Rehan, Vikas Seth, Prerna Upadhyaya · 2011 · PubMed Central
- Changes in Plasma Visfatin and Insulin Resistance Index in Obese Women with Type 2 Diabetes after Pilates ExerciseE Mir, Mehrdad Fathi · 2018 · Journal of Health and Care
- A case of generalized lipodystrophy-associated progeroid syndrome treated by leptin replacement with short and long-term monitoring of the metabolic and endocrine profilesTakahiro Fukaishi, Isao Minami, S Masuda, Yasutaka Miyachi, Kazutaka Tsujimoto, Hajime Izumiyama, Koshi Hashimoto, Masayuki Yoshida, Sayako Takahashi, Kenichi Kashimada et al. · 2019 · Endocrine Journal
- LipodystrophiesAbhimanyu Garg · 2015 · Elsevier eBooks
- A New Understanding of MetforminDavid Grahame Hardie · 2021 · Elsevier eBooks
- Dermatological Complications of Diabetes Mellitus; Allergy to Insulin and Oral AgentsGeorge I. Varghese, Ellen S. Marmur, Mathew C. Varghese · 2009 · Springer eBooks
- Update on HIV LipodystrophyStephen Kravcik · 2004 · HIV Clinical Trials
- La leptine, nouvelle perspective thérapeutique dans le traitement du diabète ?Camille Vatier, Jacqueline Capeau, Corinne Vigouroux · 2010 · médecine/sciences
- Movin' on up: Adipocytes become regulators of nutrient homeostasisRoger H. Unger, Joel Keith Elmquist · 2006 · Cell Metabolism
- Lipodistrofias: bases moleculares y manifestaciones clínicasDavid Araujo Vilar · 2003 · Endocrinología y Nutrición
- Carbohydrate, Fat, and Protein Metabolism in ObesityJ. Galgani, V. Cortes, F. Carrasco · 2015 · Springer eBooks
- Scientific evidence for therapeutic effects of Chinese prescription Kangen-karyu from pre-clinical animal experimentsTakako Yokozawa, Chan Hum Park, Kinzo Matsumoto · 2017 · Drug Discoveries & Therapeutics
- Association of Leptin Gene G2548A Polymorphism and Leptin Resistance with Insulin Resistance and Obesity among EgyptiansSara A. Aboelroos, Abdel Malik Nassar, Mohamed M. EL Shabrawy, Ranya Hassan, Ahmed Abdelellah · 2017 · Suez Canal University Medical Journal
- Structured Intermittent Interruption of Chronic HIV Infection Treatment with Highly Active Antiretroviral Therapy: Effects on Leptin and TNF- αM. Montes de Oca Arjona, R. Pérez-Cano, R. Garcia-Juárez, Andrés Martín-Aspas, Clotilde Fernández-Gutiérrez, J.A. Girón González · 2006 · AIDS Research and Human Retroviruses
- Manifestations of Adipose Tissue DysfunctionNicola I. Abate, Anne E. Sumner, Manisha Chandalia · 2013 · Journal of Obesity
- Leptin and insulin resistance: good, bad, or still unclear?Elif A Oral, Charles Burant · 2009 · American Journal of Physiology-Endocrinology and Metabolism
- Neuroendocrine Regulation of Food IntakeSamuel E. Dagogo-Jack · 2005 · CRC Press eBooks
- Cardiac Lipids by 1 H MRSLidia S. Szczepaniak, Laura G. Smith · 2016
- Anorexia Nervosa, Bulimia Nervosa, and Other Eating DisordersMelita L. Daley, Carolyn Nguyen, Robert T. Rubín · 2010 · Elsevier eBooks
- Subcutaneous FatMartin Munro Black, W. J. Cunliffe · 2004
- Mitochondrial medicineEmma Dorey · 2014 · Nature Biotechnology
- Pancreatic Islets as a Target of AdipokinesMoritz Reiterer, Ankit Gilani, James C. Lo · 2022 · Comprehensive physiology
- Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesityChandramohan Chitraju, Alexander W. Fischer, Yohannes Abere Ambaw, Kun Wang, Bo Yuan, Sheng Tony Hui, Tobias C. Walther, Robert V. Farese · 2023 · eLife
- Endocrine Regulation of Leptin ProductionRobert V. Considine · 2003 · Springer eBooks
- Changes After Leptin Administration in Partial Lipodystrophy and Factors Associated With Hepatic and Metabolic ResponseBarış Akıncı, Nevin Ajluni, Rasimcan Meral, Adam Neidert, Maria Foss de Freitas, Donatella Gilio, Hari S. Conjeevaram, Elif A Oral · 2025 · Journal of the Endocrine Society
- The Impact of Neuregulin 4 on Metabolic Dysregulation in LipodystrophyLeonie Wagner, Juliane Estrada-Kunz, Lisa Giulino Roth, Juliane Weiner, Susan Kralisch, Annett Hoffmann, Michael Stümvoll, Mathias Faßhauer, Thomas Ebert, Kerstin Krause et al. · 2025 · Endocrinology
- Leptin and Acute Lung DisordersAlice Huertas, Jahar Bhattacharya · 2025 · Comprehensive physiology
- Advances of pharmacological therapies in lipodystrophy syndromes: current evidence and future directionsÖzge Besci, Merve Çelik Güler, Maria Cristina Foss‐Freitas, Elif A Oral · 2025 · Expert Review of Endocrinology & Metabolism
- Adipokine-mediated crosstalk between metabolic dysregulation and inflammatory pathwaysZhiheng He, Linjie Zhao, Jiarui Liu, Wanjie Zheng, Chengjun Gong, Chengxuan Gong, Li Guo, Tingming Liang · 2025 · Pathology - Research and Practice
- Postmarketing Surveillance of the Safety and Effectiveness of Metreleptin in Patients with Lipodystrophy in JapanKen Ebihara, Tomohisa Hata, Yumi Sato, Makiko Miyano · 2025 · Journal of the Endocrine Society
- Pathogenesis of Hepatic Steatosis and Fibrosis: Role of LeptinFaidon Magkos, Elisa Fabbrini, Samuel Klein · 2014 · Springer eBooks
- Metreleptin therapy in LMNA-linked lipodystrophiesCamille Vatier, Corinne Vigouroux · 2015 · Orphanet Journal of Rare Diseases
- LeptinMalaka B. Jackson, Rexford S. Ahima · 2007 · Humana Press eBooks
- Uric acid is associated with morpho-functional adipose tissue markers in apparently healthy subjectsJuan Reyes-Barrera, Aída Xochitl Medina-Urrutia, Esteban Jorge Galarza, Horacio Osorio‐Alonso, Abraham Said Arellano-Buendía, Gabriela Olvera-Mayorga, Néstor A. Sánchez‐Ortiz, Margarita Torres‐Tamayo, Armando R Tovar Palacio, Iván Torre-Villalvazo et al. · 2022 · Clinica Chimica Acta
- Across-species benefits of adrenalectomy on congenital generalized lipoatrophic diabetes: a reviewPatricio H. Contreras, Pilar Vigil P · 2024 · Frontiers in Endocrinology
- Clinical features of acquired lipodystrophy after total body irradiation: a case report and mini reviewGiuseppe Ancona · 2025 · Current Medical Research and Opinion
- A real-world pharmacovigilance assessment and literature review of lymphoma development in lipodystrophyRebecca J. Brown, David Araújo‐Vilar, Kelly J. Walkovich, Alexandru Barbarosie, David A. Magee, Barış Akıncı, Elif A Oral · 2025 · Frontiers in Endocrinology
- The Investigation of Leptin (LEP) and Leptin Receptor (LEPR) Gene Variations in Obese PatientsŞermin Durak, Saadet Büşra Aksoyer Sezgin, Faruk Çelik, Murat Dıramali, İlhan Yaylım, Ali Osman Gürol, Ramazan Çakmak, Ümit Zeybek · 2025 · Clinical & Translational Metabolism
- Pathogenesis of Obstructive Sleep Apnea in ObesityJason Paul Kirkness, Susheel P. Patil · 2012 · Humana Press eBooks
- Les lipodystrophies génétiquesCamille Vatier, Guillaume Bidault, Caroline Le Dour, Véronique Béréziat, Olivier Lascols, Jacqueline Capeau, Corinne Vigouroux · 2011 · Médecine et Nutrition
- Aşırı beslenmeye bağlı oluşan insülin direncinin biyokimyasal gelişimi ve AMP-ile aktive edilmiş protein kinaz (AMPK)’ın fonksiyonuCemalettin KİSMİROĞLU, Mustafa Yaman · 2020 · European Journal of Science and Technology
- Endocrinology: past, present and futureAndrey F. Verbovoy, Yu. A. Dolgikh, N. I. Verbovaya, Rudolf A. Galkin · 2022 · Endocrinology News Opinions Training
- Control of fatty acid metabolism by leptin in L6 rat myoblasts is regulated by hyperinsulinemiaMegumi Eguchi, S. Shrivastava, Natalia Lyakhovsky, W I Kim, R. Palanivel, Gary Sweeney · 2007 · Journal of Endocrinological Investigation
- Leaping for leptin: the 2010 Albert Lasker Basic Medical Research Award goes to Douglas Coleman and Jeffrey M. FriedmanUshma S. Neill · 2010 · Journal of Clinical Investigation
- Metabolic Disorders in HIV-infected Children Metabolic Disorders in HIVinfected ChildrenSpagnuolo M Liguoro · 2014 · Journal of Metabolic Syndrome
- Síndrome de Berardinelli-Seip en diálisis peritonealJosé Joaquín Bande-Fernández, Raúl García-Castro, José Emilio Sánchez-Álvarez, Carmen Rodríguez-Suárez, Diego Coronel, Carlos Hidalgo, Beatriz Istanbuli, Carmen Merino Bueno, Laura del Rio-García · 2015 · Nefrología
- Adipokines and MetabolismRexford S. Ahima, Laura M. Scolaro, Hyeong-Kyu Park · 2015 · Springer eBooks
- Nonalcoholic Fatty Liver Disease and Adipokines: A Novel Role for Fat ImbalanceStergios A. Pοlyzos · 2013 · ImmunoGastroenterology
- Leptin and the Regulation of FeedingMartin Grosvenor Myers · 2006 · Elsevier eBooks
- Neuroendocrine Control of Energy StoresRoger D. Cone, Joel Keith Elmquist · 2016 · Elsevier eBooks
- A histomorphometric study on the effects of antiretroviral therapy (ART) combined with a high-calorie diet (HCD) on aortic perivascular adipose tissue (PVAT)Stephan Nel, Hans Strijdom, Amanda Genis, Frans Everson, R. Van Wijk, Sanet H. Kotzé · 2017 · Acta Histochemica
- Anorexia Nervosa, Bulimia Nervosa, and Other Eating DisordersIrina Kowalska, Monika Karczewska‐Kupczewska, Marek Strączkowski, Robert T. Rubín · 2015 · Elsevier eBooks
- Berardinelli-Seip Syndrome: Report of an Old Case Successfully Treated with Anti-Glucocorticoid Therapy Followed by Bilateral AdrenalectomyPatricio H. Contreras · 2022 · IntechOpen eBooks
- Leptin ResistanceYong‐Woon Kim · 2007 · Journal of Korean Endocrine Society
- Carbohydrate, Fat, and Protein Metabolism in ObesityJosé Eduardo Galgani, Vı́ctor Cortés, Fernando Carrasco N · 2016 · Springer eBooks
- Lipodystrophies and DyslipidemiasAbhimanyu Garg · 2015 · Contemporary Endocrinology
- Metabolic Mechanisms of Muscle Insulin ResistanceDeborah M. Muoio, Timothy R. Koves, Jie An, Christopher B. Newgard · 2008 · Humana Press eBooks
- Mediators of Insulin ResistanceRocio I. Pereira, David M. Maahs · 2009 · Humana Press eBooks
- Protein pieces of adipose tissue secretory puzzleFatma Töre, Neşe Tunçel · 2007 · Biomedical Reviews
- Experiência de pessoas que vivem com a Síndrome de Berardinelli-Seip no Nordeste brasileiroÉverson de Brito Damasceno, Jakson Gomes de Figueiredo, Jean Marcel Bezerra França, Júlio Cesar Duarte Veras, Raul Elton Araújo Borges, Lucas Pereira de Melo · 2018 · Ciência & Saúde Coletiva
- In Silico Disulfide Bond Engineering to Improve Human LEPTIN StabilityBahram Barati, Fatemeh Fazeli Zafar, Shuanhu Hu, Najmeh Fani, Sajjad Eshtiaghi, Shuang Wang · 2021 · JOURNAL OF RENEWABLE MATERIALS
- Obesity and Disease: Hormones and ObesityJonathan H. Pinkney · 2005 · Wiley eBooks
- The emerging clinical significance of leptin in humans with absolute or relative leptin deficiencyStergios J. Moschos, Christos Socrates Mantzoros · 2005 · Current Opinion in Internal Medicine
- Treatment of partial lipodystrophy: can the zebra teach us about the horse?Robert Alexander Hegele · 2004 · Drug Discovery Today Disease Mechanisms
- Adipocyte BiologyPaul Trayhurn · 2009 · Wiley eBooks
- Monogenic Causes of DiabetesShivani Misra, Andrew Tym Hattersley · 2016 · Wiley eBooks
- Neurophysiology of the endocrine systemKiran Prakash, Manpreet Kaur, Shival Srivastav, Mahesh Arjundan Gadhvi, Renuka Sharma · 2024 · Elsevier eBooks
- Lipodystrophiesyndrome – klinische Präsentation und ManagementMarianna Beghini, Thomas Scherer · 2024 · Journal für Endokrinologie Diabetologie und Stoffwechsel
- Adipsin and Leptin Levels in Type 2 Diabetic Patients on Sitagliptin and Metformin Versus Metformin TherapySura Khalid Mohammed · 2024 · SiSli Etfal Hastanesi Tip Bulteni / The Medical Bulletin of Sisli Hospital
- Effects of FGF21, soluble TGFBR2, and environmental temperature on metabolic dysfunction in lipodystrophic miceJessica N. Maung, Yang Chen, Keegan S. Hoose, Rose E. Adler, Hadla Hariri, Mia J. Dickson, Taryn A. Hetrick, Gabriel A. Ferguson, Rebecca L. Schill, Hiroyuki Mori et al. · 2025 · JCI Insight
- Long-Term Clinical Experience With Metreleptin in a Brazilian Patient With Congenital Generalized Lipodystrophy Type 2Isabella Sued Leão, Joana Rodrigues Dantas, Sarah Galvão, Melanie Rodacki, Lenita Zajdenverg · 2025 · JCEM Case Reports
- Leptin Therapy Improves Metabolic Dysfunction in Immune Checkpoint Inhibitor–induced LipodystrophyMona Vahidi Rad, Suhail M Saad-Omer, B. J. Bindu, Vinaya Simha · 2025 · JCEM Case Reports