Estrogen plus Progestin and the Risk of Coronary Heart Disease

Manson, JoAnn E., Hsia, Judith, Johnson, Karen C., Rossouw, Jacques E., Assaf, Annlouise R., Lasser, Norman L., Trevisan, Maurizio, Black, Henry R. +7 more·2003·New England Journal of Medicine

DOI 10.1056/nejmoa030808

Cited by (1,001)

Items 501–600 of 1,001

The Effect of Acupuncture on Postmenopausal Symptoms and Reproductive Hormones: A Sham Controlled Clinical Trial
Didem Sunay, Muruvvet Ozdiken, Huseyin Arslan, Ali Seven, Yalçın Aral · 2011 · Acupuncture in Medicine
The Role of Estradiol in Traumatic Brain Injury: Mechanism and Treatment Potential
Erzsébet Kövesdi, Edina Szabó‐Meleg, István M. Ábrahám · 2020 · International Journal of Molecular Sciences
Trust in Scientific Experts on Obesity: Implications for Awareness and Behavior Change
Sara N. Bleich, Robert J. Blendon, Alyce Sophia Adams · 2007 · Obesity
Lipid Profiles in Women With 45,X vs 46,XX Primary Ovarian Failure
Margaret M. Cooley · 2003 · JAMA
Cardioprotection by chronic estrogen or superoxide dismutase mimetic treatment in the aged female rat
Yi Xu, Stephen J. Armstrong, Ivan A. Arenas, Daniel J. Pehowich, Sandra Thomas Davidge · 2004 · American Journal of Physiology-Heart and Circulatory Physiology
Evidence-based guidelines for cardiovascular disease prevention in women
Livia de Paula Caetano Mosca, L.J Appel, Emelia J. Benjamin · 2004 · ACC Current Journal Review
Emerging Selective Estrogen Receptor Modulators
Tatjana E. Vogelvang, Marius J. van der Mooren, Velja Mijatovic, Peter Kenemans · 2006 · Drugs
A randomised controlled trial of cognitive-behavioural therapy for women with problematic menopausal hot flushes: MENOS 2 trial protocol
Beverley Ayers, Eleanor Mann, Myra Sally Hunter · 2011 · BMJ Open
Proteomic risk markers for coronary heart disease and stroke: validation and mediation of randomized trial hormone therapy effects on these diseases
Ross L. Prentice, Shanshan Zhao, Melissa M. Johnson, Aaron K. Aragaki, Judith A. Hsia, Rebecca D. Jackson, Jacques E. Rossouw, JoAnn E. Manson, Samir Hanash · 2013 · Genome Medicine
A simulation using data from a primary care practice database closely replicated the women's health initiative trial
Richard L. Tannen, Mark G. Weiner, Dawei Xie, Kurt Thomas Barnhart · 2006 · Journal of Clinical Epidemiology
Gender and estrogen supplementation increases severity of experimental choroidal neovascularization
Diego G. Espinosa‐Heidmann, Maria E. Marin‐Castaño, Simone Pereira‐Simon, Eleut P. Hernandez, Sharon J. Elliot, Scott W. Cousins · 2004 · Experimental Eye Research
Systemic lupus erythematosus in a multiethnic US cohort (LUMINA): XXI. Disease activity, damage accrual, and vascular events in pre‐ and postmenopausal women
Mónica Fernández, Jaime Calvo Alén, Graciela S. Alarcón, Jeffrey M. Roseman, Holly M. Bastian, Barri J. Fessler, Gerald McGwin, Luis M. Vilá, Martha L. Sanchez, John D. Reveille et al. · 2005 · Arthritis & Rheumatism
Clinical Management of Takotsubo Cardiomyopathy
Raymond E. Bietry, Alex Reyentovich, Stuart D. Katz · 2013 · Heart Failure Clinics
Estrogen and salt sensitivity in the female mRen(2).Lewis rat
Mark C. Chappell, Liliya M. Yamaleyeva, Brian M. Westwood · 2006 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Cardiovascular Risk in Women With Non-Specific Chest Pain (from the Women's Health Initiative Hormone Trials) † ‡
Jennifer G. Robinson, Robert B. Wallace, Marian C. Limacher, Hong Ren, Barbara B. Cochrane, Sylvia W Wassertheil-Smoller, Judith K. Ockene, Patricia Lanoie Blanchette, Marcia G. Ko · 2008 · The American Journal of Cardiology
Activation of nitric oxide synthesis in human endothelial cells by red clover extracts
Tommaso Simoncini, Letizia Fornari, Paolo Mannella, Antonella Caruso, Silvia Garibaldi, Chiara Baldacci, Andrea Riccardo Genazzani · 2005 · Menopause The Journal of The North American Menopause Society
Managing the menopause
Helen Roberts · 2007 · BMJ
Influence of Maternal Dysmetabolic Conditions During Pregnancy on Cardiovascular Disease
Wulf Palinski, Eric Nicolaides, Antonio Liguori, Claudio Napoli A · 2009 · Journal of Cardiovascular Translational Research
Effects of low and high dose oestradiol and dydrogesterone therapy on insulin and lipoprotein metabolism in healthy postmenopausal women
Ian F. Godsland, N Manassiev, Carl V. Felton, Anthony J. Proudler, David Crook, Malcolm I. Whitehead, John C. Stevenson · 2004 · Clinical Endocrinology
Gender Differences in Outcome of Conservatively Treated Patients With Asymptomatic High Grade Carotid Stenosis
Petra Dick, Camillo Sherif, Schila Sabeti, Jasmin Amighi, Erich Minar, Martin Schillinger · 2005 · Stroke
Menopausal Hormone Therapy
Bhagu R. Bhavnani, Ronald C. Strickler · 2005 · Journal of Obstetrics and Gynaecology Canada
Postmenopausal hormone therapy in clinical perspective
Howard Neil Hodis, Wendy Jean Mack · 2007 · Menopause The Journal of The North American Menopause Society
Hormone use and patient concerns after the findings of the Women's Health Initiative
Sharon J. Rolnick, Richard A. Kopher, Terese A. DeFor, Mary E. Kelley · 2005 · Menopause The Journal of The North American Menopause Society
Riluzole improves outcome following ischemia–reperfusion injury to the spinal cord by preventing delayed paraplegia
Yongchao Wu, Kajana Satkunendrarajah, Michael George Fehlings · 2014 · Neuroscience
Properties of 2 Counterfactual Effect Definitions of a Point Exposure
W. Dana Flanders, Mitchel Klein · 2007 · Epidemiology
Treating hot flushes in menopausal women with homeopathic treatment–Results of an observational study
Marie-France Bordet, Aurélie Colas, Philippe Marijnen, J.-F. Masson, M Trichard · 2008 · Homeopathy
Should Progestins Be Blamed for the Failure of Hormone Replacement Therapy to Reduce Cardiovascular Events in Randomized Controlled Trials?
Kwang Kon Koh, Ichiro Sakuma · 2004 · Arteriosclerosis Thrombosis and Vascular Biology
Ovariectomy enhances SR Ca2+ release and increases Ca2+ spark amplitudes in isolated ventricular myocytes
Elias Fares, Randi J. Parks, Jennifer K. MacDonald, Jeanne Egar, Susan Ellen Howlett · 2011 · Journal of Molecular and Cellular Cardiology
Impact of hormone replacement on myocardial fatty acid metabolism: Potential role of estrogen
Pilar Herrero, Pablo F. Soto, Carmen S. Dence, Zulfia Kisrieva-Ware, Deborah A. Delano, Linda R. Peterson, Robert J. Gropler · 2005 · Journal of Nuclear Cardiology
Effect of genetic variations in platelet glycoproteins Ibα and VI on the risk for coronary heart disease events in postmenopausal women taking hormone therapy
Paul F. Bray, Timothy D. Howard, Eric Vittinghoff, David C. Sane, David M. Herrington · 2006 · Blood
Estrogen actions in the cardiovascular system
Michael E. Mendelsohn · 2009 · Climacteric
Effects of dehydroepiandrosterone (DHEA) on cardiovascular risk factors in older women with frailty characteristics
Rebecca S. Boxer, Alison Kleppinger, Jennifer Brindisi, Richard Feinn, J. Burleson, Rose Anne Kenny · 2010 · Age and Ageing
Risk Factors for Age-Related Maculopathy
Paul Connell, Pearse Andrew Keane, Evelyn C. O’Neill, Rasha Al‐Taie, Edward Loane, Kumari Neelam, John M. Nolan, Stephen Beatty · 2009 · Journal of Ophthalmology
Vascular Inflammation and Atherosclerosis: The Role of Estrogen Receptors
Eva N. Kassi, Eliana Spilioti, Narjes Nasiri Ansari, Christos Adamopoulos, Paraskevi Moutsatsou, Angeliki Papapanagiotou, Gerasimos Siasos, Dimitris Tousoulis, Athanasios G. Papavassiliou · 2015 · Current Medicinal Chemistry
Challenges and Novel Approaches in the Epidemiological Study of Early Life Influences on Later Disease
George Davey Smith, Sam D. Leary, Andy Ness, Debbie A. Lawlor · 2009 · Advances in experimental medicine and biology
Sex and Gender Aspects in Vascular Ageing – Focus on Epidemiology, Pathophysiology, and Outcomes
Ute Seeland, János Nemcsik, Mai Tone Lønnebakken, Karolina R. Kublickiene, Helena Schluchter, Chloe M. Park, Giacomo Pucci, Ioana Monica Mozos, Rosa María Bruno · 2021 · Heart Lung and Circulation
Committee Opinion No. 565
2013 · Obstetrics and Gynecology
Management of hypertension in women
Niels Engberding, NANETTE KASS WENGER · 2011 · Hypertension Research
A critique of Women’s Health Initiative Studies (2002-2006)
Clark · 2007 · Nuclear Receptor Signaling
Association of oestrogen receptor alpha gene polymorphism with the angiographic extent of coronary artery disease
Arthur Pollak · 2004 · European Heart Journal
Future Directions for Cardiovascular Disease Comparative Effectiveness Research
Mark Andrew Hlatky, Pamela S. Douglas, Nakela L. Cook, Barbara L. Wells, Emelia J. Benjamin, Kay Dickersin, David Calvin Goff, Alan T. Hirsch, Elaine M. Hylek, Eric David Peterson et al. · 2012 · Journal of the American College of Cardiology
Cardiovascular diseases in American women
Ying Zhang · 2010 · Nutrition Metabolism and Cardiovascular Diseases
Vascular Disease in Diabetic Women: Why Do They Miss the Female Protection?
Ana Paula Dantas, Zuleica Bruno Fortes, Maria Helena Catelli de Carvalho · 2012 · Experimental Diabetes Research
Hypertension in women: the role of progesterone and aldosterone
Ewald Boschitsch, S. Mayerhofer, D Magometschnigg · 2010 · Climacteric
Increasing use of prescription drugs in the United Kingdom
Frank Zhang, Ronac Mamtani, Frank I. Scott, David Seth Goldberg, Kevin Haynes, James D. Lewis · 2015 · Pharmacoepidemiology and Drug Safety
Menopausal Hormone Therapy Is Associated With Increased Risk of Fecal Incontinence in Women After Menopause
Kyle D. Staller, Mary K. Townsend, Hamed Khalili, Raaj S. Mehta, Francine Grodstein, William E. Whitehead, Catherine Ann Matthews, Braden Kuo, Andrew Tan Chan · 2017 · Gastroenterology
Menopausal Hormone Therapy and Risks of First Hospitalized Heart Failure and its Subtypes During the Intervention and Extended Postintervention Follow-up of the Women's Health Initiative Randomized Trials
Longjian Liu, Liviu Klein, Charles B. Eaton, Gurusher Singh Panjrath, Lisa Warsinger Martin, Claudia U. Chae, Philip Greenland, Donald M. Lloyd‐Jones, Jean Wactawski‐Wende, JoAnn E. Manson · 2019 · Journal of Cardiac Failure
Arterial and venous thrombosis: What's the link? A narrative review
Aurélien Delluc, Karine Lacut, Marc Alan Rodger · 2020 · Thrombosis Research
Relaxin as a natural agent for vascular health
Danièle Bani · 2008 · Vascular Health and Risk Management
Chronic disease prevention: public health potential and research needs
Ross L. Prentice · 2004 · Statistics in Medicine
Estrogen Decreases Atherosclerosis in Part by Reducing Hepatic Acyl-CoA:Cholesterol Acyltransferase 2 (ACAT2) in Monkeys
Kylie Kavanagh, Matthew A. Davis, Li Zhang, Martha D. Wilson, Thomas C. Register, Michael R. Adams, Lawrence L. Rudel, Janice D. Wagner · 2009 · Arteriosclerosis Thrombosis and Vascular Biology
Differential and Opposing Regulation of PAI-1 Promoter Activity by Estrogen Receptor α and Estrogen Receptor β in Endothelial Cells
Layton Harris Smith, Stephen R. Coats, Hao Qin, Matthew S. Petrie, Joseph W. Covington, Ming Su, Mesut Eren, Douglas E. Vaughan · 2004 · Circulation Research
Heart Failure and its Treatment in Women
Vera Regitz‐Zagrosek, Elke Lehmkuhl · 2005 · Herz
Menopausal estrogen therapy counteracts normal aging effects on intima thickness, media thickness and intima/media ratio in carotid and femoral arteries
Tord Naessén, Kenny A. Rodriguez‐Wallberg · 2006 · Atherosclerosis
A Contemporary View of Menopausal Hormone Therapy
Barbara S. Levy, James A. Simon · 2024 · Obstetrics and Gynecology
Multidisciplinary Strategy for Managing Cardiovascular Risks When Treating Patients with Early Breast Cancer
Daniel John Lenihan, Francisco J. Esteva · 2008 · The Oncologist
Postmenopausal estrogen and progestin effects on the serum proteome
Sharon J. Pitteri, Samir Hanash, Aaron K. Aragaki, Lynn M. Amon, Lin Chen, Tina Busald Buson, Sophie Paczesny, Hiroyuki Katayama, Hong Wang, Melissa M. Johnson et al. · 2009 · Genome Medicine
HRT and cardiovascular disease
John C. Stevenson · 2008 · Best Practice & Research Clinical Obstetrics & Gynaecology
Estrogen potentiates constrictor prostanoid function in female rat aorta by upregulation of cyclooxygenase-2 and thromboxane pathway expression
Min Li, Lih Kuo, John N. Stallone · 2008 · American Journal of Physiology-Heart and Circulatory Physiology
Postmenopausal hormone therapy before and after the women's health initiative study: what consequences?
Tomi S. Mikkola, Thomas B. Clarkson, Morris Notelovitz · 2004 · Annals of Medicine
Hormone therapy and Alzheimer?s disease: benefit or harm?
Victor W. Henderson · 2004 · Expert Opinion on Pharmacotherapy
Safety and benefit considerations for menopausal hormone therapy
James H. Pickar, David F. Archer, Risa Kagan, JoAnn V. Pinkerton, Hugh Stott Taylor · 2017 · Expert Opinion on Drug Safety
Prevalence and management of hypertension in acute coronary syndrome patients varies by sex: Observations from the Sibrafiban versus aspirin to Yield Maximum Protection from ischemic Heart events postacute cOroNary sYndromes (SYMPHONY) randomized clinical trials
Camille G. Frazier‐Mills, Svati Hasmukh Shah, Paul W. Armstrong, Manjushri V. Bhapkar, Darren K. McGuire, Zygmunt Sadowski, Arni Kristinsson, Philip E. Aylward, Werner W Klein, W. Douglas Weaver et al. · 2005 · American Heart Journal
Menopausal Hormone Therapy and Cardiovascular Disease Risk: Utility of Biomarkers and Clinical Factors for Risk Stratification
Shari S. Bassuk, JoAnn E. Manson · 2013 · Clinical Chemistry
Targeted basic research to highlight the role of estrogen and estrogen receptors in the cardiovascular system
Elke Dworatzek, Shokoufeh Mahmoodzadeh · 2017 · Pharmacological Research
The hypertensive potential of estrogen: An untold story
Manal Fardoun, Hassan Dehaini, Abdullah A. Shaito, Joelle Edward Mesmar, Ahmed Fawzy EL‐Yazbi, Adnan Badran, Elias Beydoun, Ali Hussein Eid · 2019 · Vascular Pharmacology
Sex hormone ratio changes in men and postmenopausal women with coronary artery disease
Hong He, Falin Yang, Xianxi Liu, Xianwei Zeng, Qin Hu, Qing xia Zhu, Bing Tu · 2006 · Menopause The Journal of The North American Menopause Society
Hormone replacement therapy and age-related brain shrinkage: regional effects
Naftali Raz, Karen M. Rodrigue, Kristen M. Kennedy, James D. Acker · 2004 · Neuroreport
Old and new cardiovascular risk factors: from unresolved issues to new opportunities
Renke Maas, Rainer H. Böger · 2003 · Atherosclerosis Supplements
Ischemic and bleeding outcomes in women treated with bivalirudin during percutaneous coronary intervention: A subgroup analysis of the Randomized Evaluation in PCI Linking Angiomax to Reduced Clinical Events (REPLACE)–2 trial
Matthews Chacko, Abraham Michael Lincoff, Katherine E. Wolski, David J. Cohen, John A. Bittl, Alexandra J. Lansky, Yoshihiro Tsuchiya, Amadeo Betriu, Michael H. Yen, Derek P. Chew et al. · 2006 · American Heart Journal
Advances in hormone replacement therapy with drospirenone, a unique progestogen with aldosterone receptor antagonism
Santiago Palacios, Jean‐Michel Foidart, Andrea Ricardo Genazzani · 2006 · Maturitas
Testosterone replacement therapy for late-onset hypogonadism
Glenn R. Cunningham · 2006 · Nature Clinical Practice Urology
Unique features of dyslipidemia in women across a lifetime and a tailored approach to management
Neeja Patel, Nikita Mittal, Michael J. Wilkinson, Pam R. Taub · 2024 · American Journal of Preventive Cardiology
European Code against Cancer 4th Edition: Medical exposures, including hormone therapy, and cancer
Søren Friis, Ausrele Kesminiene, Carolina Espina, Anssi P. Auvinen, Kurt Straíf, Joachim Schüz · 2015 · Cancer Epidemiology
Effect of Hormone Replacement Therapy on Cardiovascular Outcomes: A Meta-Analysis of Randomized Controlled Trials
Dicheng Yang, Jing Li, Zhongxiang Yuan, Xu Liu · 2013 · PLoS ONE
Osteoporosis treatment and atrial fibrillation
Weng-Foung Huang, Yi‐Wen Tsai, Yu‐Wen Wen, Fei‐Yuan Hsiao, Ken N. Kuo, Chia-Rung Tsai · 2010 · Menopause The Journal of The North American Menopause Society
Effect of Dietary Fiber Intake on Lipoprotein Cholesterol Levels Independent of Estradiol in Healthy Premenopausal Women
Sunni L. Mumford, Enrique F. Schisterman, Anna Maria Siega‐Riz, Audrey Jane Gaskins, Jean Wactawski‐Wende, Tyler J. VanderWeele · 2010 · American Journal of Epidemiology
Risk of Inflammatory Bowel Disease with Oral Contraceptives and Menopausal Hormone Therapy: Current Evidence and Future Directions
Hamed Khalili · 2015 · Drug Safety
Italian association of clinical endocrinologists (AME) position statement: drug therapy of osteoporosis
Fabio Vescini, Roberto Attanasio, A. Balestrieri, Francisco Alfredo Farias Bandeira, Stefania Bonadonna, Valentina Camozzi, Sara Cassibba, R. Cesareo, Iacopo Chiodini, Cristiano Maria Francucci et al. · 2016 · Journal of Endocrinological Investigation
Drug Therapy for Stable Angina Pectoris
Talla A. Rousan, Sunil T. Mathew, Udho Thadani · 2017 · Drugs
Estrogen effects on arteries vary with stage of reproductive life and extent of subclinical atherosclerosis progression
Thomas B. Clarkson · 2018 · Menopause The Journal of The North American Menopause Society
Relationship between Postmenopausal Estrogen Deficiency and Aneurysmal Subarachnoid Hemorrhage
Sadaharu Tabuchi · 2015 · Behavioural Neurology
Effect of aromatase inhibition on lipids and inflammatory markers of cardiovascular disease in elderly men with low testosterone levels
Ryan H. Dougherty, Jacqueline L. Rohrer, Douglas Hayden, Stephen D. Rubin, Benjamin Z. Leder · 2005 · Clinical Endocrinology
Have we come full circle – or moved forward? The Women's Health Initiative 10 years on
Robert D. Langer, JoAnn E. Manson, Matthew Allison · 2012 · Climacteric
Surrogate end-points or primary outcomes in clinical trials in women with polycystic ovary syndrome?
Richard S. Legro · 2004 · Human Reproduction
Sex matters to the heart: A special issue dedicated to the impact of sex related differences of cardiovascular diseases
Hester M. den Ruijter, Saskia Haitjema, Folkert Wouter Asselbergs, Gerard Pasterkamp · 2015 · Atherosclerosis
Systemic Effects of Vaginally Administered Estrogen Therapy
Megan L. Krause, Thomas L. Wheeler, Holly Elizabeth Richter, Thomas E. Snyder · 2010 · Urogynecology
Identification of Menopausal and Reproductive Risk Factors for Microscopic Colitis—Results From the Nurses’ Health Study
Kristin E. Burke, Ashwin N. Ananthakrishnan, Paul J. Lochhead, Po‐Hong Liu, Ola Olén, Jonas Filip Ludvigsson, James M. Richter, Shelley S. Tworoger, Andrew Tan Chan, Hamed Khalili · 2018 · Gastroenterology
Postmenopausal oral estrogen therapy and blood pressure in normotensive and hypertensive subjects: the Estrogen in the Prevention of Atherosclerosis Trial
Anne Z. Steiner, Howard Neil Hodis, Rogerio A. Løbo, Donna Shoupe, Min Xiang, Wendy Jean Mack · 2005 · Menopause The Journal of The North American Menopause Society
The forthcoming role of treatment with oestrogens in mental health
Geyter De · 2007 · Swiss Medical Weekly
Use of Hormone Replacement Therapy by Postmenopausal Women After Publication of the Women's Health Initiative Trial
Jose Ness, Wilbert S. Aronow, Erin N Newkirk, Deanna L. McDanel · 2005 · The Journals of Gerontology Series A
Age at Menopause, Leukocyte Telomere Length, and Coronary Artery Disease in Postmenopausal Women
Art Schuermans, Tetsushi Nakao, Md Mesbah Uddin, Whitney Hornsby, Shriienidhie Ganesh, Aladdin H. Shadyab, Simin Liu, Bernhard Haring, CHRISANDRA L. SHUFELT, Margaret A. Taub et al. · 2023 · Circulation Research
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Alberico Luigi Catapano, Ian M Graham, Guy De Backer, Olov Wiklund, M. John Chapman, Heinz Drexel, Arno Wilhelmus Hoes, Catriona Sian Jennings, Ulf Landmesser, Terje Rolf Pedersen et al. · 2016 · Kardiologia Polska
Different mechanisms for benefit and risk of coronary heart disease and stroke in early postmenopausal women
Rogerio A. Løbo, Tom B. Clarkson · 2010 · Menopause The Journal of The North American Menopause Society
Lasofoxifene, a new selective estrogen receptor modulator for the treatment of osteoporosis and vaginal atrophy
Luigi Gennari · 2009 · Expert Opinion on Pharmacotherapy
Progestogens regulate endothelial actin cytoskeleton and cell movement via the actin-binding protein moesin
Xiaodong Fu, Marina Inés Flamini, Angel Matías Sanchez, Lorenzo Goglia, Maria Silvia Giretti, Andrea Riccardo Genazzani, Tommaso Simoncini · 2008 · Molecular Human Reproduction
Postmenopausal Hormone Therapy and Cardiovascular Disease in Perspective
Howard Neil Hodis, Wendy Jean Mack · 2008 · Clinical Obstetrics & Gynecology
After the women’s health initiative: Decision making and trust of women taking hormone therapy
Mara A. Schonberg, Roger B. Davis, Christina C. Wee · 2005 · Women s Health Issues
Mortality associated with hormone replacement therapy in younger and older women
Shelley R. Salpeter · 2006 · Journal of General Internal Medicine
Invited Commentary: Off-Roading With Social Epidemiology—Exploration, Causation, Translation
M. Maria Glymour, Theresa L. Osypuk, David H. Rehkopf · 2013 · American Journal of Epidemiology