Mutations in TERT, the Gene for Telomerase Reverse Transcriptase, in Aplastic Anemia

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Items 301–400 of 725

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5. Making Therapeutic Decisions in Adults with Aplastic Anemia
   Judith C. W. Marsh · 2006 · Hematology
6. Consequences of telomere shortening during lifespan
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7. The wide-ranging clinical implications of the Short Telomere Syndromes
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8. Short Telomeres Resulting from Heritable Mutations in the Telomerase Reverse Transcriptase Gene Predispose for a Variety of Malignancies
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9. Telomere length is severely and similarly reduced in JAK2V617F-positive and -negative myeloproliferative neoplasms
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10. Telomerase as a “stemness” enzyme
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11. Telomere dysfunction and stem cell ageing
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12. Recent progress in dyskeratosis congenita
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13. Haematopoietic stem and progenitor cells in rheumatoid arthritis.
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14. Telomeres and Telomerase in Stem Cells during Aging and Disease
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15. A homozygous telomerase T-motif variant resulting in markedly reduced repeat addition processivity in siblings with Hoyeraal Hreidarsson syndrome
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16. Red Blood Cell and Bleeding Disorders
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17. Bone marrow skeletal stem/progenitor cell defects in dyskeratosis congenita and telomere biology disorders
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18. Telomeres in lung disease
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19. Updates on the pathophysiology and treatment of aplastic anemia: a comprehensive review
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20. iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors
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21. Structural, functional, and stability change predictions in human telomerase upon specific point mutations
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22. Hepatitis-Associated Aplastic Anemia
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23. Hypoplastic myelodysplastic syndrome and acquired aplastic anemia: Immune‑mediated bone marrow failure syndromes (Review)
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24. Medical genetics and epigenetics of telomerase
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25. Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Bone Marrow Failure Syndromes
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26. High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegans
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27. Genetics and Genodermatoses
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28. Missing Cells: Pathophysiology, Diagnosis, and Management of (Pan)Cytopenia in Childhood
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29. At the stem of youth and health
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30. Telomere length maintenance in stem cell populations
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31. Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice
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32. CURRENT DIAGNOSIS OF INHERITED BONE MARROW FAILURE SYNDROMES
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33. Understanding telomere diseases through analysis of patient-derived iPS cells
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34. Effect of Danggui Buxue Tang on immune-mediated aplastic anemia bone marrow proliferation mice
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35. Short telomeres and high telomerase activity in T-cell prolymphocytic leukemia
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36. Telomerase reverse transcriptase haploinsufficiency and telomere length in individuals with 5p– syndrome
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37. Telomerase: not just for the elongation of telomeres
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38. DNA damage response in adult stem cells
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39. Syngeneic transplantation in aplastic anemia: pre-transplant conditioning and peripheral blood are associated with improved engraftment: an observational study on behalf of the Severe Aplastic Anemia and Pediatric Diseases Working Parties of the European Group for Blood and Marrow Transplantation
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40. Dysfunctional Bone Marrow Mesenchymal Stem Cells in Patients with Poor Graft Function after Allogeneic Hematopoietic Stem Cell Transplantation
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41. Relapse of aplastic anemia in children after immunosuppressive therapy: a report from the Japan Childhood Aplastic Anemia Study Group
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42. Stress, social rank and leukocyte telomere length
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43. Inherited bone marrow failure syndromes in 2012
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44. Tieing together loose ends: telomere instability in cancer and aging
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45. Dyskerin, telomerase and the DNA damage response
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46. The prediction of the wild-type telomerase RNA pseudoknot structure and the pivotal role of the bulge in its formation
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47. Deciphering the genetics and mechanisms of predisposition to multiple myeloma
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48. Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis
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49. Maintenance of telomere length in AML
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50. Telomere dysfunction in human diseases: the long and short of it!
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51. ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IS SUPERIOR TO IMMUNOSUPPRESSIVE THERAPY IN INDIAN CHILDREN WITH APLASTIC ANEMIA—A SINGLE-CENTER ANALYSIS OF 100 PATIENTS
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52. Telomerase Reverse Transcriptase Polymorphism rs2736100: A Balancing Act between Cancer and Non-Cancer Disease, a Meta-Analysis
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53. Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure
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54. Telomere biology of the chicken: A model for aging research
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55. Telomerase Mutations and the Pulmonary Fibrosis–Bone Marrow Failure Syndrome Complex
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56. Pulmonary Fibrosis and a TERT Founder Mutation With a Latency Period of 300 Years
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57. Telomerase enzyme deficiency promotes metabolic dysfunction in murine hepatocytes upon dietary stress
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58. Genetic polymorphisms, mRNA expression levels of telomere-binding proteins, and associates with telomere damage in PAHs–Exposure workers
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59. Unravelling the role of telomere shortening with ageing and their potential association with diabetes, cancer, and related lifestyle factors
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60. Acquired Aplastic Anemia in Childhood
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63. A structurally conserved human and Tetrahymena telomerase catalytic core
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64. Single-cell transcriptomics identifies premature aging features of TERC-deficient mouse brain and bone marrow
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67. Childhood Maltreatment in Bipolar Disorders
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68. Next-generation Sequencing in Bone Marrow Failure Syndromes and Isolated Cytopenias: Experience of the Spanish Network on Bone Marrow Failure Syndromes
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75. Telomere biology and telomerase mutations in cirrhotic patients with hepatocellular carcinoma
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80. Naive T-cells in myelodysplastic syndrome display intrinsic human telomerase reverse transcriptase (hTERT) deficiency
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86. Mutations of Telomerase Complex Genes Linked to Bone Marrow Failures
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90. Human short-term repopulating cells have enhanced telomerase reverse transcriptase expression
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92. Aplastic Anemia as a Roadmap for Bone Marrow Failure: An Overview and a Clinical Workflow
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94. Clinical and genetic features of dyskeratosis congenita, cryptic dyskeratosis congenita, and Hoyeraal-Hreidarsson syndrome in Japan
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95. Aplastic Anemia: Management of Adult Patients
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96. Prolonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cells
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97. Recent Advances and Long-Term Results of Medical Treatment of Acquired Aplastic Anemia
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98. The known genetic loci for telomere length may be involved in the modification of telomeres length after birth
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99. Dysfunctional telomeres and dyskeratosis congenita
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100. Genetic dissection of the mechanisms underlying telomere-associated diseases: impact of the TRF2 telomeric protein on mouse epidermal stem cells
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