A Randomized Trial of Intensive Lipid-Lowering Therapy in Calcific Aortic Stenosis

Cowell, S. Joanna, Newby, David E., Prescott, Robin J., Bloomfield, Peter, Reid, John, Northridge, David B., Boon, Nicholas A.·2005·New England Journal of Medicine

Cited by (1,000)

Items 101–200 of 1,000

  1. A prospective, double-blind, randomized controlled trial of the angiotensin-converting enzyme inhibitor Ramipril In Aortic Stenosis (RIAS trial)
    Sacha Bull, Margaret A. Loudon, Jane M Francis, Jubin P Joseph, Stephen Gerry, Theodoros D. Karamitsos, Bernard Prendergast, ADRIAN P BANNING, Stefan Neubauer, Saul G. Myerson · 2015 · European Heart Journal - Cardiovascular Imaging
  2. Cardiovascular effects of statins, beyond lipid-lowering properties
    Christos G. Mihos, Andrés M. Pineda, Orlando Santana · 2014 · Pharmacological Research
  3. Inhibiting PCSK9 — biology beyond LDL control
    Stoekenbroek, Robert M., Lambert, Gilles, Cariou, Bertrand, Hovingh, G. Kees · 2019 · Nature Reviews Endocrinology
  4. Runx2 Expression in Smooth Muscle Cells Is Required for Arterial Medial Calcification in Mice
    Mu-En Lin, Theodore Chen, Elizabeth M. Leaf, Mei Y. Speer, Cecilia M. Giachelli · 2015 · American Journal Of Pathology
  5. Incidence, risk factors, clinical impact, and management of bioprosthesis structural valve degeneration
    Nancy Côté, Philippe Pîbarot, Marie-Annick A Clavel · 2017 · Current Opinion in Cardiology
  6. An exploratory analysis of proprotein convertase subtilisin/kexin type 9 inhibition and aortic stenosis in the FOURIER trial
    Bergmark, Brian A., O’Donoghue, Michelle L., Murphy, Sabina A., Kuder, Julia F., Ezhov, Marat V., Ceška, Richard, Gouni-Berthold, Ioanna, Jensen, Henrik K., Tokgozoglu, S. Lale, Mach, François et al. · 2020 · JAMA Cardiology
  7. Potential drug targets for calcific aortic valve disease
    Joshua D. Hutcheson, Elena Rabkin Aikawa, W. David Merryman · 2014 · Nature Reviews Cardiology
  8. Animal Models of Calcific Aortic Valve Disease
    Krista L. Sider, Mark C. Blaser, Craig A. Simmons · 2011 · International Journal of Inflammation
  9. PCSK9 R46L loss-of-function mutation reduces lipoprotein(a), LDL cholesterol, and risk of aortic valve stenosis
    Langsted, Anne, Nordestgaard, Børge G., Benn, Marianne, Tybjærg-Hansen, Anne, Kamstrup, Pia R. · 2016 · The Journal of Clinical Endocrinology & Metabolism
  10. A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis
    Thériault, Sébastien, Gaudreault, Nathalie, Lamontagne, Maxime, Rosa, Mickael, Boulanger, Marie-Chloé, Messika-Zeitoun, David, Clavel, Marie-Annick, Capoulade, Romain, Dagenais, François, Pibarot, Philippe et al. · 2018 · Nature Communications
  11. Angiotensin Receptor-1 Blocker Inhibits Atherosclerotic Changes and Endothelial Disruption of the Aortic Valve in Hypercholesterolemic Rabbits
    Kumiko Arishiro, Masaaki Hoshiga, Nobuyuki Negoro, Denan Jin, Shinji Takai, Mizuo Miyazaki, Tadashi Ishihara, Toshiaki Hanafusa · 2007 · Journal of the American College of Cardiology
  12. Reduced Sox9 Function Promotes Heart Valve Calcification Phenotypes In Vivo
    Jacqueline D. Peacock, Agata K. Levay, Devin B. Gillaspie, Ge Tao, Joy Lincoln · 2010 · Circulation Research
  13. Aortic valve stenosis: an active atheroinflammatory process
    Satu Helske, Markku M. Kupari, Ken A. Lindstedt, Petri T. Kovanen · 2007 · Current Opinion in Lipidology
  14. Left Ventricular Hypertrophy With Strain and Aortic Stenosis
    Anoop S.V. Shah, Calvin Chin, Vassilios S. Vassiliou, S. Joanna Cowell, Mhairi Katrina Doris, T’ng Choong Kwok, Scott Semple, Vipin Zamvar, Audrey C. White, Graham McKillop et al. · 2014 · Circulation
  15. Imaging Cardiovascular Calcification
    Ying Wang, Michael Thomas Osborne, Brian Tung, Ming Li, Yaming Li · 2018 · Journal of the American Heart Association
  16. Cholesterol Lowering, Cardiovascular Diseases, and the Rosuvastatin-JUPITER Controversy
    Michel de Lorgeril · 2010 · Archives of Internal Medicine
  17. Impact of Metabolic Syndrome on Progression of Aortic Stenosis
    Capoulade, Romain, Clavel, Marie-Annick, Dumesnil, Jean G., Chan, Kwan L., Teo, Koon K., Tam, James W., Côté, Nancy, Mathieu, Patrick, Després, Jean-Pierre, Pibarot, Philippe · 2012 · Journal of the American College of Cardiology
  18. Inflammatory and metabolic mechanisms underlying the calcific aortic valve disease
    Kyoung Im Cho, Ichiro Sakuma, Il Suk Sohn, Sang‐Ho Jo, Kwang Kon Koh · 2018 · Atherosclerosis
  19. A High Fat/High Carbohydrate Diet Induces Aortic Valve Disease in C57BL/6J Mice
    Marie‐Claude Drolet, Élise Roussel, Yves Deshaies, Jacques Couët, Marie Arsenault · 2006 · Journal of the American College of Cardiology
  20. Triglycerides and remnant cholesterol associated with risk of aortic valve stenosis: Mendelian randomization in the Copenhagen General Population Study
    Kaltoft, Morten, Langsted, Anne, Nordestgaard, Børge G · 2020 · European Heart Journal
  21. Association between circulating oxidised low-density lipoprotein and fibrocalcific remodelling of the aortic valve in aortic stenosis
    Côté, C, Pibarot, P, Després, J-P, Mohty, D, Cartier, A, Arsenault, B J, Couture, C, Mathieu, P · 2008 · Heart
  22. Lipid Lowering on Progression of Mild to Moderate Aortic Stenosis: Meta-analysis of the Randomized Placebo-Controlled Clinical Trials on 2344 Patients
    Koon Kang Teo, Daniel J. Corsi, James W. Tam, Jean Gaston Dumesnil, Kwan Leung Chan · 2011 · Canadian Journal of Cardiology
  23. Associations of Long-Term and Early Adult Atherosclerosis Risk Factors With Aortic and Mitral Valve Calcium
    Thanassoulis, George, Massaro, Joseph M., Cury, Ricardo, Manders, Emily, Benjamin, Emelia J., Vasan, Ramachandran S., Cupple, L. Adrienne, Hoffmann, Udo, O'Donnell, Christopher J., Kathiresan, Sekar · 2010 · Journal of the American College of Cardiology
  24. Temporal Trends in the Incidence and Prognosis of Aortic Stenosis
    Andreas Martinsson, Xinjun Li, Charlotte Andersson, Johan Nilsson, J. Gustav Smith, Kristina Sundquist · 2015 · Circulation
  25. Relationship of Metabolic Syndrome With Incident Aortic Valve Calcium and Aortic Valve Calcium Progression
    Ronit Katz, Matthew Jay Budoff, Junichiro Takasu, David M. Shavelle, Alain Gerald Bertoni, Roger Scott Blumenthal, Pamela Ouyang, Nathan D. Wong, Kevin D. O’Brien · 2009 · Diabetes
  26. Evaluating Medical Therapy for Calcific Aortic Stenosis
    Brian R. Lindman, Devraj Sukul, Marc Richard Dweck, Mahesh V. Madhavan, Benoît J. Arsenault, Megan J. Coylewright, W. David Merryman, David Ernest Newby, John Lewis, Frank E. Harrell et al. · 2021 · Journal of the American College of Cardiology
  27. Upregulation of the 5-Lipoxygenase Pathway in Human Aortic Valves Correlates With Severity of Stenosis and Leads to Leukotriene-Induced Effects on Valvular Myofibroblasts
    Edit Nagy, Daniel C. Andersson, Kenneth Caidahl, Maria J. Eriksson, Per Olof Eriksson, Anders Franco‐Cereceda, Göran K. Hansson, Magnus Bäck · 2011 · Circulation
  28. Increased Expression of Elastolytic Cathepsins S, K, and V and Their Inhibitor Cystatin C in Stenotic Aortic Valves
    Satu Helske, Suvi Syväranta, Ken A. Lindstedt, Jani Lappalainen, Katariina Öörni, Mikko Ilari Mäyränpää, Jyri Lommi, Heikki Turto, Kalervo Werkkala, Markku M. Kupari et al. · 2006 · Arteriosclerosis Thrombosis and Vascular Biology
  29. Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice
    Zeng Qingchun, Rui Song, David A. Fullerton, Lihua Ao, Yufeng Zhai, Suzhao Li, Dov B. Ballak, Joseph C. Cleveland, Thomas Brett Reece, Timothy A. McKinsey et al. · 2017 · Proceedings of the National Academy of Sciences
  30. Role of oxidative stress in calcific aortic valve disease and its therapeutic implications
    Harry Z.E. Greenberg, Guoan Zhao, Ajay M. Shah, Min Zhang · 2021 · Cardiovascular Research
  31. Lipid‐mediated inflammation and degeneration of bioprosthetic heart valves
    Rahul C. Shetty, Philippe Pîbarot, Audrey Audet, Régis Janvier, François Dagenais, J. Perron, Christian Couture, Pierre Voisine, Jean‐Pierre Després, Patrick Mathieu · 2009 · European Journal of Clinical Investigation
  32. Critical appraisal of C-reactive protein throughout the spectrum of cardiovascular disease
    Raed Osman, Philippe L. L’Allier, Nader Z. Elgharib, Jean‐Claude Tardif · 2006 · Vascular Health and Risk Management
  33. Prognosis and risk factors in patients with asymptomatic aortic stenosis and their modulation by atorvastatin (20 mg)
    Dichtl, Wolfgang, Alber, Hannes Franz, Feuchtner, Gudrun Maria, Hintringer, Florian, Reinthaler, Markus, Bartel, Thomas, Süssenbacher, Alois, Grander, Wilhelm, Ulmer, Hanno, Pachinger, Otmar et al. · 2008 · The American Journal of Cardiology
  34. Evidence for Active Regulation of Pro-Osteogenic Signaling in Advanced Aortic Valve Disease
    Jordan D. Miller, Robert M. Weiss, Kristine M. Serrano, Lauren E. Castaneda, Robert M. Brooks, Kathy Zimmerman, Donald D. Heistad · 2010 · Arteriosclerosis Thrombosis and Vascular Biology
  35. A three-dimensional co-culture model of the aortic valve using magnetic levitation
    Hubert Tseng, Liezl Rae Balaoing, Bagrat Grigoryan, Robert M. Raphael, T. C. Killian, Glauco R. Souza, Kathryn Jane Grande-Allen · 2013 · Acta Biomaterialia
  36. Degenerative calcific aortic stenosis: a natural history
    Iung, Bernard, Vahanian, Alec · 2012 · Heart
  37. Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease
    Theodoris, Christina V., Zhou, Ping, Liu, Lei, Zhang, Yu, Nishino, Tomohiro, Huang, Yu, Kostina, Aleksandra, Ranade, Sanjeev S., Gifford, Casey A., Uspenskiy, Vladimir et al. · 2021 · Science
  38. Cardiac valve cells and their microenvironment—insights from in vitro studies
    Huan Wang, Leslie Anne Leinwand, Kristi S. Anseth · 2014 · Nature Reviews Cardiology
  39. Diagnosis and Management of Valvular Aortic Stenosis
    Matthew J. Czarny, Jon R. Resar · 2014 · Clinical Medicine Insights Cardiology
  40. High prevalence of amyloid in 150 surgically removed heart valves—a comparison of histological and clinical data reveals a correlation to atheroinflammatory conditions
    Arnt V. Kristen, Philipp Albert Schnabel, Bettina Winter, Burkhard Maria Helmke, Thomas Longerich, Stefan E. Hardt, Achim Koch, Falk‐Udo Sack, Hugo Albert Katus, Reinhold Paul LINKE et al. · 2009 · Cardiovascular Pathology
  41. Heart Valve Biomechanics and Underlying Mechanobiology
    Salma Ayoub, Giovanni Maria Ferrari, Robert C. Gorman, Joseph H. Gorman, Frederick J. Schöen, Michael S. Sacks · 2016 · Comprehensive physiology
  42. Aortic valve calcification: basic science to clinical practice
    Kemal Marc Akat, Martin M. Borggrefe, Jens J. Kaden · 2008 · Heart
  43. Unmet needs in valvular heart disease
    David Messika–Zeitoun, Helmut Baumgartner, Ian G. Burwash, Alec S. Vahanian, Jeroen Joost Bax, Philippe Pîbarot, Vincent Chan, Martin B. Leon, Maurice L. Enriquez-Sarano, Thierry G. Mesana et al. · 2023 · European Heart Journal
  44. Antioxidant Enzymes Reduce DNA Damage and Early Activation of Valvular Interstitial Cells in Aortic Valve Sclerosis
    Emanuela Branchetti, Rachana Sainger, Paolo Poggio, Juan B. Grau, Jeffrey Patterson-Fortin, Joseph E. Bavaria, Michael Chorny, Eric K. Lai, Robert C. Gorman, Robert J. Levy et al. · 2012 · Arteriosclerosis Thrombosis and Vascular Biology
  45. Systolic hypertension and progression of aortic valve calcification in patients with aortic stenosis: results from the PROGRESSA study
    Tastet, Lionel, Capoulade, Romain, Clavel, Marie-Annick, Larose, Éric, Shen, Mylène, Dahou, Abdellaziz, Arsenault, Marie, Mathieu, Patrick, Bédard, Élisabeth, Dumesnil, Jean G. et al. · 2017 · European Heart Journal – Cardiovascular Imaging
  46. A clinical risk score of myocardial fibrosis predicts adverse outcomes in aortic stenosis
    Calvin Chin, David Messika–Zeitoun, Anoop S.V. Shah, Guillaume Lefèvre, Sophie Bailleul, Emily Yeung, Maria Koo, Saeed Mirsadraee, Tiffany Mathieu, Scott I K Semple et al. · 2015 · European Heart Journal
  47. Lipoprotein(a) is associated with the onset but not the progression of aortic valve calcification
    Yannick Kaiser, Janine E. van der Toorn, Sunny S Singh, Kang H. Zheng, Maryam Kavousi, Eric J.G. Sijbrands, Erik S.G. Stroes, Meike Willemijn Vernooij, Yolanda B. de Rijke, S. Matthijs Boekholdt et al. · 2022 · European Heart Journal
  48. Calcific Aortic Stenosis: A Review
    Otto, Catherine M., Newby, David E., Hillis, Graham S. · 2024 · JAMA
  49. The progression of calcific aortic valve disease through injury, cell dysfunction, and disruptive biologic and physical force feedback loops
    Chen Li, Songyi Xu, Avrum I. Gotlieb · 2012 · Cardiovascular Pathology
  50. Pathophysiology of Aortic Stenosis and Future Perspectives for Medical Therapy
    Kang H. Zheng, Evangelos Tzolos, Marc Richard Dweck · 2019 · Cardiology Clinics
  51. Early aortic valve inflammation precedes calcification: A longitudinal FDG-PET/CT study
    Abdelbaky, Amr, Corsini, Erin, Figueroa, Amparo L., Subramanian, Sharath, Fontanez, Sara, Emami, Hamed, Hoffmann, Udo, Narula, Jagat, Tawakol, Ahmed · 2015 · Atherosclerosis
  52. Mechanisms of aortic stenosis
    Hirokuni Akahori, Takeshi Tsujino, Tohru Masuyama, Masaharu Ishihara · 2017 · Journal of Cardiology
  53. Effect of Statins on Venous Thromboembolic Events: A Meta-analysis of Published and Unpublished Evidence from Randomised Controlled Trials
    Kazem Rahimi, Neeraj B. Bhala, Pieter Willem Kamphuisen, Jonathan Emberson, Sara Biere‐Rafi, Vera Krane, Michele Robertson, John Wikstrand, John J.V. McMurray · 2012 · PLoS Medicine
  54. The Pleiotropic Effects of the Hydroxy-Methyl-Glutaryl-CoA Reductase Inhibitors in Cardiovascular Disease
    Christos G. Mihos, Maria J. Salas, Orlando Santana · 2010 · Cardiology in Review
  55. Development of calcific aortic valve disease: Do we know enough for new clinical trials?
    Alexander E. Kostyunin, Arseniy E. Yuzhalin, Evgeny Andreevich Ovcharenko, Антон Геннадьевич Кутихин · 2019 · Journal of Molecular and Cellular Cardiology
  56. Valvular heart disease: from mechanisms to management
    Fabien Praz, Friedhelm Beyersdorf, Kristina Hermann Haugaa, Bernard Prendergast · 2024 · The Lancet
  57. Lipoprotein (a) in calcific aortic valve disease: from genomics to novel drug target for aortic stenosis
    George Thanassoulis · 2015 · Journal of Lipid Research
  58. Warfarin and aortic valve calcification in hemodialysis patients
    Rachel Mary Holden, Anthony J. Sanfilippo, Wilma M. Hopman, Deborah Lynn Zimmerman, Jocelyn S. Garland, A. Ross Morton · 2007 · Journal of Nephrology
  59. Adaptive immune cells in calcific aortic valve disease
    Michael A. Raddatz, Meena S. Madhur, W. David Merryman · 2019 · American Journal of Physiology-Heart and Circulatory Physiology
  60. Biomarkers of Calcific Aortic Valve Disease
    Aeron Small, Daniel Kiss, Jay S. Giri, Saif Anwaruddin, Hasan Khalid Siddiqi, Marie A. Guerraty, Julio A. Chirinos, Giovanni Maria Ferrari, Daniel James Rader · 2017 · Arteriosclerosis Thrombosis and Vascular Biology
  61. Genetic Association Analyses Highlight <i>IL6</i> , <i>ALPL</i> , and <i>NAV1</i> As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis
    Thériault, Sébastien, Dina, Christian, Messika-Zeitoun, David, Le Scouarnec, Solena, Capoulade, Romain, Gaudreault, Nathalie, Rigade, Sidwell, Li, Zhonglin, Simonet, Floriane, Lamontagne, Maxime et al. · 2019 · Circulation: Genomic and Precision Medicine
  62. Aortic Stenosis Progression
    Nadav Asher Willner, Graeme Prosperi‐Porta, Lawrence Lau, Angel Yi Nam Fu, Kevin E. Boczar, Anthony Poulin, Pietro Di Santo, Rudy R Unni, Sarah May Visintini, Paul Everett Ronksley et al. · 2022 · JACC. Cardiovascular imaging
  63. 2025 ESC/EACTS Guidelines for the management of valvular heart disease
    Fabien Praz, Michael Andrew Borger, Jonas Lanz, Mateo Marin Cuartas, Ana Abreu, Marianna Adamo, Nina Ajmone Marsan, Fabio Barili, Nikolaos E. Bonaros, Bernard Cosyns et al. · 2025 · European Journal of Cardio-Thoracic Surgery
  64. Imaging of the Aortic Valve Using Fluorodeoxyglucose Positron Emission Tomography
    Gergana Marincheva-Savcheva, Sharath S. Subramanian, Sadia Qadir, Amparo L. Figueroa, Quynh A. Truong, Jayanthi Vijayakumar, Thomas J. Brady, Udo Hoffmann, Ahmed A Tawakol · 2011 · Journal of the American College of Cardiology
  65. Lipoprotein(a) and oxidized phospholipids in calcific aortic valve stenosis
    Calvin Yeang, Michael J. Wilkinson, Sotirios Tsimikas · 2016 · Current Opinion in Cardiology
  66. Vitamin K2 and D in Patients With Aortic Valve Calcification: A Randomized Double-Blinded Clinical Trial
    Axel C.P. Diederichsen, Jes S. Lindholt, Sören Möller, Kristian A. Øvrehus, Søren Auscher, Jess Lambrechtsen, Susanne Elisabeth Hosbond, Dilek H. Alan, Grazina Urbonaviciene, Søren W. Becker et al. · 2022 · Circulation
  67. Potential Causality and Emerging Medical Therapies for Lipoprotein(a) and Its Associated Oxidized Phospholipids in Calcific Aortic Valve Stenosis
    Sotirios Tsimikas · 2019 · Circulation Research
  68. Intraleaflet haemorrhage is associated with rapid progression of degenerative aortic valve stenosis
    Hirokuni Akahori, T. Tsujino, Y Naito, Mika Matsumoto, Masaaki Lee‐Kawabata, Mitsumasa Ohyanagi, Masataka Mitsuno, Yuji Miyamoto, Takashi Daimon, Hiroyuki Hao et al. · 2010 · European Heart Journal
  69. Inhibition of calcifying nodule formation in cultured porcine aortic valve cells by nitric oxide donors
    Jennifer A. Kennedy, Xiang Hua, Kumaril Mishra, Geraldine A. Murphy, Anke C. Rosenkranz, John David Horowitz · 2008 · European Journal of Pharmacology
  70. Lipoprotein(a)-Associated Molecules Are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis
    Michael Torzewski, Amir Ravandi, Calvin Yeang, Andrea L. Edel, Rahul Bhindi, Stefan Kath, Laura Twardowski, Jens O. Schmid, Xiaohong Yang, Ulrich F W Franke et al. · 2017 · JACC Basic to Translational Science
  71. Three-dimensional imaging of the aortic valve and aortic root with computed tomography: new standards in an era of transcatheter valve repair/implantation
    Paul Schoenhagen, Emin Murat Tuzcu, S. R. Kapadia, Milind Y. Desai, Lars Georg Svensson · 2009 · European Heart Journal
  72. Calcific Aortic Valve Disease-Natural History and Future Therapeutic Strategies
    Brunilda Alushi, Lavinia Curini, Mary Roxana Christopher, Herko Grubitzch, Ulf Landmesser, Amedeo Amedei, Alexander Lauten · 2020 · Frontiers in Pharmacology
  73. Stage-Related Effect of Statin Treatment on the Progression of Aortic Valve Sclerosis and Stenosis
    Francesco Antonini‐Canterin, Monica Hîrşu, Bogdan Alexandru Popescu, Elisa Leiballi, Rita Piazza, Daniela Pavan, Carmen Ginghină, Gian Luigi Nicolosi · 2008 · The American Journal of Cardiology
  74. Valvular Heart Disease
    Catherine M Otto, Robert O. Bonow · 2012 · Elsevier eBooks
  75. Innate and adaptive immunity: the understudied driving force of heart valve disease
    Francesca Bartoli‐Leonard, Jonas Zimmer, Elena Rabkin Aikawa · 2021 · Cardiovascular Research
  76. Management of Asymptomatic Severe Aortic Stenosis
    Jacob P. Dal‐Bianco, Bjoy K. Khandheria, Farouk Mookadam, Federico Gentile, Partho P. Sengupta · 2008 · Journal of the American College of Cardiology
  77. Endoplasmic Reticulum Stress Participates in Aortic Valve Calcification in Hypercholesterolemic Animals
    Zhejun Cai, Fei Li, Wei Gong, Wanjun Liu, Quanlu Duan, Chen Chen, Li Ni, Yong Xia, Katherine Cianflone, Nianguo Dong et al. · 2013 · Arteriosclerosis Thrombosis and Vascular Biology
  78. Oxidized Phospholipids and Risk of Calcific Aortic Valve Disease
    Pia R. Kamstrup, Ming‐Yow Hung, Joseph Lee Witztum, Sotirios Tsimikas, Børge Grønne Nordestgaard · 2017 · Arteriosclerosis Thrombosis and Vascular Biology
  79. Inflammation and Cardiovascular Diseases in the Elderly: The Role of Epicardial Adipose Tissue
    Maddalena Conte, Laura Petraglia, Paolo Poggio, Vincenza Valerio, Serena Cabaro, Pasquale Campana, Giuseppe Comentale, Emilio Attena, Vincenzo Russo, Emanuele Pilato et al. · 2022 · Frontiers in Medicine
  80. Association between degenerative aortic valve disease and long-term exposure to cardiovascular risk factors: results of the longitudinal population-based KORA/MONICA survey
    Jan Stritzke, Patrick Linsel‐Nitschke, Marcello Ricardo Paulista Markus, Bernd Mayer, Wolfgang Lieb, Andreas Luchner, Angela Döring, Wolfgang Köenig, Ulrich Keil, H. W. Hense et al. · 2009 · European Heart Journal
  81. Aortic Valve Sclerosis and Clinical Outcomes: Moving Toward a Definition
    Shahyar Michael Gharacholou, Barry L. Karon, Clarence Shub, Patricia A. Pellikka · 2011 · The American Journal of Medicine
  82. Haemodynamic and anatomic progression of aortic stenosis
    Nguyen, Virginia, Cimadevilla, Claire, Estellat, Candice, Codogno, Isabelle, Huart, Virginie, Benessiano, Joelle, Duval, Xavier, Pibarot, Philippe, Clavel, Marie Annick, Enriquez-Sarano, Maurice et al. · 2015 · Heart
  83. Omega-3 Polyunsaturated Fatty Acids Decrease Aortic Valve Disease Through the Resolvin E1 and ChemR23 Axis
    Gonzalo Artiach, Miguel Carracedo, Oscar Plunde, Craig Edward Wheelock, Silke Thul, Peter Sjövall, Anders Franco‐Cereceda, Andrés Laguna-Fernández, Hildur H. Arnardottir, Magnus Bäck · 2020 · Circulation
  84. The effect of statins on valve function and calcification in aortic stenosis: a meta-analysis
    Zhao, Ying, Nicoll, Rachel, He, Yi hua, Henein, Michael Y. · 2016 · Atherosclerosis
  85. Lipoprotein(a) and Calcific Aortic Valve Stenosis Progression: A Systematic Review and Meta-Analysis
    Arsenault, Benoit J., Loganath, Krithika, Girard, Arnaud, Botezatu, Simona, Zheng, Kang H., Tzolos, Evangelos, Abdoun, Kathia, Tastet, Lionel, Capoulade, Romain, Côté, Nancy et al. · 2024 · JAMA Cardiology
  86. Contemporary Perioperative Results of Isolated Aortic Valve Replacement for Aortic Stenosis
    S. Chris Malaisrie, Patrick M. McCarthy, Edwin C. McGee, Richard Lee, Vera H. Rigolin, Charles J. Davidson, Nirat Beohar, Brittany R. Lapin, Haris P. Subacius, Robert O. Bonow · 2010 · The Annals of Thoracic Surgery
  87. Uncoupling the Vicious Cycle of Mechanical Stress and Inflammation in Calcific Aortic Valve Disease
    Nalin H. Dayawansa, Sara Baratchi, Karlheinz Peter · 2022 · Frontiers in Cardiovascular Medicine
  88. Post-stenotic aortic dilatation
    Emma Wilton, Marjan Jahangiri · 2006 · Journal of Cardiothoracic Surgery
  89. Cholesterol in Vascular and Valvular Calcification
    Linda L. Demer · 2001 · Circulation
  90. ApoB/ApoA-I Ratio Is Associated With Increased Risk of Bioprosthetic Valve Degeneration
    Haïfa Mahjoub, Patrick Mathieu, Mario Sénéchal, Éric Larose, Jean Gaston Dumesnil, Jean‐Pierre Després, Philippe Pîbarot · 2013 · Journal of the American College of Cardiology
  91. Atherosclerotic-like process in aortic stenosis: Activation of the tissue factor–thrombin pathway and potential role through osteopontin alteration
    Joke Breyne, Françis Juthier, Delphine Corseaux, Sylvestre Maréchaux, Christophe Zawadzki, Emmanuelle Jeanpierre, Alexandre Ung, Pierre‐Vladimir Ennezat, Sophie Susen, Eric VAN BELLE et al. · 2010 · Atherosclerosis
  92. Differential proteoglycan and hyaluronan distribution in calcified aortic valves
    Elizabeth H. Stephens, Jerome G. Saltarrelli, L. Scott Baggett, Indrajit Nandi, Joyce J. Kuo, Alan R. Davis, Elizabeth A. Olmsted‐Davis, Michael J. Reardon, Joel D. Morrisett, Kathryn Jane Grande-Allen · 2010 · Cardiovascular Pathology
  93. Asymptomatic Aortic Stenosis in the Elderly
    Warren J. Manning · 2013 · JAMA
  94. Nonrheumatic calcific aortic stenosis: an overview from basic science to pharmacological prevention☆
    Alessandro Parolari, Claudia Maria Loardi, L. Mussoni, Laura Cavallotti, Marina Camera, Paolo Biglioli, Elena Tremoli, Francesco Alamanni · 2009 · European Journal of Cardio-Thoracic Surgery
  95. Cardiovascular Disease in the Elderly
    Janice B. Schwartz, Douglas Peter Zipes · 2012 · Elsevier eBooks
  96. Calcific Aortic Valve Disease: a Developmental Biology Perspective
    Punashi Dutta, Joy Lincoln · 2018 · Current Cardiology Reports
  97. Reasons for Nonadherence to Guidelines for Aortic Valve Replacement in Patients With Severe Aortic Stenosis and Potential Solutions
    Benjamin H. Freed, Lissa Sugeng, Kathleen Furlong, Victor Mor‐Avi, Jai Raman, Valluvan Jeevanandam, Roberto Miguel Lang · 2010 · The American Journal of Cardiology
  98. Statins Block Calcific Nodule Formation of Valvular Interstitial Cells by Inhibiting α-Smooth Muscle Actin Expression
    Julie A. Benton, Hanna B. Kern, Leslie Anne Leinwand, Peter D. Mariner, Kristi S. Anseth · 2009 · Arteriosclerosis Thrombosis and Vascular Biology
  99. Effects of Phosphodiesterase Type 5 Inhibition on Systemic and Pulmonary Hemodynamics and Ventricular Function in Patients With Severe Symptomatic Aortic Stenosis
    Brian R. Lindman, Alan Zajarías, José Madrazo, Jay Shah, Brian F. Gage, Eric L. Novak, Stephanie N. Johnson, Murali M. Chakinala, Tara A. Hohn, Mohammed Saghir et al. · 2012 · Circulation
  100. Unraveling the Mechanisms of Valvular Heart Disease to Identify Medical Therapy Targets: A Scientific Statement From the American Heart Association
    Aeron Small, Katherine E. Yutzey, Bryce Anthony Binstadt, Kaitlin Voigts Key, Nabila Bouatia‐Naji, David Milan, Elena Aïkawa, Catherine M Otto, Cynthia St. Hilaire · 2024 · Circulation