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The DOI matches its Crossref record; 101 of the 101 references it cites were found in a registry or an index.

Hepatitis E Virus Infection

Open access
Kamar, Nassim, Dalton, Harry R., Abravanel, Florence, Izopet, Jacques·2014·Clinical Microbiology Reviews

Abstract

SUMMARY: Hepatitis E virus (HEV) infection is a worldwide disease. An improved understanding of the natural history of HEV infection has been achieved within the last decade. Several reservoirs and transmission modes have been identified. Hepatitis E is an underdiagnosed disease, in part due to the use of serological assays with low sensitivity. However, diagnostic tools, including nucleic acid-based tests, have been improved. The epidemiology and clinical features of hepatitis E differ between developing and developed countries. HEV infection is usually an acute self-limiting disease, but in developed countries it causes chronic infection with rapidly progressive cirrhosis in organ transplant recipients, patients with hematological malignancy requiring chemotherapy, and individuals with HIV. HEV also causes extrahepatic manifestations, including a number of neurological syndromes and renal injury. Acute infection usually requires no treatment, but chronic infection should be treated by reducing immunosuppression in transplant patients and/or the use of antiviral therapy. In this comprehensive review, we summarize the current knowledge about the virus itself, as well as the epidemiology, diagnostics, natural history, and management of HEV infection in developing and developed countries.

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Metadata

Authors
Kamar, N., Dalton, H. R., Abravanel, F., & Izopet, J.
Venue
Clinical Microbiology Reviews
Published
2014-01
Volume
27
Issue
1
Pages
116-138
ISSN
  • 0893-8512 (ISSN-L)
  • 1098-6618
OpenAlex
W2127999679
Cited by
675
References
101
FWCI
35.66
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Hepatitis E Virus Infection. https://app.cochat.ai/papers/10.1128/cmr.00057-13
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Kamar, N., Dalton, H. R., Abravanel, F., & Izopet, J. (2014). Hepatitis E Virus Infection. Clinical Microbiology Reviews. https://doi.org/10.1128/cmr.00057-13

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.