Cited by 1,585Atrial Fibrillation Management and OutcomesCardiac pacing and defibrillation studiesHeart Failure Treatment and Management

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Rhythm Control versus Rate Control for Atrial Fibrillation and Heart Failure

Roy, Denis, Talajic, Mario, Nattel, Stanley, Wyse, D. George, Dorian, Paul, Lee, Kerry L., Bourassa, Martial G., Arnold, J. Malcolm O., Buxton, Alfred E., Camm, A. John, Connolly, Stuart J., Dubuc, Marc, Ducharme, Anique, Guerra, Peter G., Hohnloser, Stefan H., Lambert, Jean, Le Heuzey, Jean-Yves, O'Hara, Gilles, Pedersen, Ole Dyg, Rouleau, Jean-Lucien, Singh, Bramah N., Stevenson, Lynne Warner, Stevenson, William G., Thibault, Bernard, Waldo, Albert L.·2008·New England Journal of Medicine

DOI 10.1056/nejmoa0708789

Open this paper in CoChat — free account

Abstract

BACKGROUND: It is common practice to restore and maintain sinus rhythm in patients with atrial fibrillation and heart failure. This approach is based in part on data indicating that atrial fibrillation is a predictor of death in patients with heart failure and suggesting that the suppression of atrial fibrillation may favorably affect the outcome. However, the benefits and risks of this approach have not been adequately studied. METHODS: We conducted a multicenter, randomized trial comparing the maintenance of sinus rhythm (rhythm control) with control of the ventricular rate (rate control) in patients with a left ventricular ejection fraction of 35% or less, symptoms of congestive heart failure, and a history of atrial fibrillation. The primary outcome was the time to death from cardiovascular causes. RESULTS: A total of 1376 patients were enrolled (682 in the rhythm-control group and 694 in the rate-control group) and were followed for a mean of 37 months. Of these patients, 182 (27%) in the rhythm-control group died from cardiovascular causes, as compared with 175 (25%) in the rate-control group (hazard ratio in the rhythm-control group, 1.06; 95% confidence interval, 0.86 to 1.30; P=0.59 by the log-rank test). Secondary outcomes were similar in the two groups, including death from any cause (32% in the rhythm-control group and 33% in the rate-control group), stroke (3% and 4%, respectively), worsening heart failure (28% and 31%), and the composite of death from cardiovascular causes, stroke, or worsening heart failure (43% and 46%). There were also no significant differences favoring either strategy in any predefined subgroup. CONCLUSIONS: In patients with atrial fibrillation and congestive heart failure, a routine strategy of rhythm control does not reduce the rate of death from cardiovascular causes, as compared with a rate-control strategy. (ClinicalTrials.gov number, NCT00597077.)

Integrity signals

Registry

Crossref · 10.1056/nejmoa0708789

Cites

41 of 41 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Amiodarone or an Implantable Cardioverter–Defibrillator for Congestive Heart Failure
Bardy, G. H., Lee, K. L., Mark, D. B., Poole, J. E., Packer, D. L., Boineau, R., Domanski, M., Troutman, C., Anderson, J., Johnson, G., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043399 · Cited by 6,552
Effects of Enalapril on Mortality in Severe Congestive Heart Failure
The Consensus Trial Study Group* (1987) · New England Journal of Medicine · doi:10.1056/nejm198706043162301 · Cited by 5,109
Impact of Atrial Fibrillation on the Risk of Death: The Framingham Heart Study
Benjamin, E. J., Wolf, P. A., D’Agostino, R. B., Silbershatz, H., Kannel, W. B., & Levy, D. (1998) · Circulation · doi:10.1161/01.cir.98.10.946 · Cited by 4,575
A comparison of rate control and rhythm control in patients with atrial fibrillation
(2002) · New England Journal of Medicine · doi:10.1056/nejmoa021328 · Cited by 4,405
ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation): Developed in Collaboration With the European Heart Rhythm Association and the Heart Rhythm Society
Fuster, V., Rydén, L. E., Cannom, D. S., Crijns, H. J., Curtis, A. B., Ellenbogen, K. A., Halperin, J. L., Le Heuzey, J.-Y., Kay, G. N., Lowe, J. E., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.177292 · Cited by 2,805
Self-citation
A Comparison of Rate Control and Rhythm Control in Patients with Recurrent Persistent Atrial Fibrillation
Gelder, I. C. V., Hagens, V. E., Bosker, H. A., Kingma, J. H., Otto Kamp, B., Kingma, T., Said, S. A., Darmanata, J. I., Timmermans, A. J. M., Tijssen, J. G. P., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa021375 · Cited by 2,355
Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications
Feinberg, W. M. (1995) · Archives of Internal Medicine · doi:10.1001/archinte.155.5.469 · Cited by 2,282
ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death
Zipes, D. P., Camm, A. J., Borggrefe, M., Buxton, A. E., CHAITMAN, B. R., FROMER, M. A., Gregoratos, G., Klein, G. J., Myerburg, R. J., Quiñones, M. A., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.07.010 · Cited by 1,975
Temporal Relations of Atrial Fibrillation and Congestive Heart Failure and Their Joint Influence on Mortality: The Framingham Heart Study
Wang, T. J., Larson, M. G., Levy, D., Vasan, R. S., Leip, E. P., Wolf, P. A., D’Agostino, R. B., Murabito, J. M., Kannel, W. B., & Benjamin, E. J. (2003) · Circulation · doi:10.1161/01.cir.0000072767.89944.6e · Cited by 1,970
Cardiovascular Medicine at the Turn of the Millennium: Triumphs, Concerns, and Opportunities
Braunwald, E. (1997) · New England Journal of Medicine · doi:10.1056/nejm199711063371906 · Cited by 1,426

Flagged first, then by citations

Show all 41 references

Research works printed but not linked: 1

Carson PE, 1993, Circulation, 87, VI

Sorted by citations

Items 401–500 of 999

In Silico Optimization of Atrial Fibrillation-Selective Sodium Channel Blocker Pharmacodynamics
Aguilar, M., Vigmond, E. J., Nattel, S., & Comtois, P. (2012) · Biophysical Journal · doi:10.1016/j.bpj.2012.01.032 · Cited by 28
Heart failure, diastolic dysfunction and atrial fibrillation; mechanistic insight of a complex inter-relationship
Caldwell, J. C., & Mamas, M. A. (2010) · Heart Failure Reviews · doi:10.1007/s10741-010-9204-4 · Cited by 29
Ganglioneuroma presenting as an asymptomatic huge posterior mediastinal and retroperitoneal tumor.
Chang, C.-Y., Hsieh, Y.-L., Hung, G., Pan, C., & Hwang, B. (2003) · PubMed · Cited by 29
A New Landscape for Stroke Prevention in Atrial Fibrillation
Banerjee, A., Marín, F. R., & Lip, G. Y. H. (2011) · Stroke · doi:10.1161/strokeaha.111.617886 · Cited by 28
Prognostic impact of atrial fibrillation progression in a community study: AFBAR Study (Atrial Fibrillation in the Barbanza Area Study)
García‐Castelo, A., García‐Seara, J., Otero-Raviña, F., Lado, M., Vizcaya, A., Vidal, J. M., Lafuente, R., Bouza, D., Lear, P., & González‐Juanatey, J. R. (2010) · International Journal of Cardiology · doi:10.1016/j.ijcard.2010.08.042 · Cited by 28
Antiarrhythmic Drug Therapy for Atrial Fibrillation
Sardar, M. R., Saeed, W., & Kowey, P. R. (2016) · Heart Failure Clinics · doi:10.1016/j.hfc.2015.08.017 · Cited by 28
Heart Failure in Patients With Atrial Fibrillation Is Associated With a High Symptom and Hospitalization Burden: The RealiseAF Survey
Silva‐Cardoso, J., Zharinov, O. J., Ponikowski, P. P., Naditch‐Brûlé, L., Lewalter, T., Brette, S., Steg, P. G., & on behalf of the RealiseAF Investigators (2013) · Clinical Cardiology · doi:10.1002/clc.22209 · Cited by 28
Does intensity of rate control influence outcome in persistent atrial fibrillation?
Groenveld, H. F., Crijns, H. J. G. M., Rienstra, M., van den Berg, M. P., van Veldhuisen, D. J., & Gelder, I. C. V. (2009) · American Heart Journal · doi:10.1016/j.ahj.2009.09.007 · Cited by 29
Long-term outcome after catheter ablation for atrial fibrillation: safety, efficacy and impact on prognosis
Hunter, R. J., & SCHILLING, R. J. (2010) · Heart · doi:10.1136/hrt.2010.194613 · Cited by 28
Cardiovascular risk profile and management of atrial fibrillation in India: Real world data from RealiseAF survey
Narasimhan, C., Verma, J. S., Kishore, A. G. R., Singh, B. B., Dani, S., Chawala, K., Haque, A., Khan, A., Nair, M., Vora, A. M., et al. (2016) · Indian Heart Journal · doi:10.1016/j.ihj.2015.12.011 · Cited by 28
Patient-Centred Care of Older Adults With Cardiovascular Disease and Multiple Chronic Conditions
Kim, D. H., & Rich, M. W. (2016) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2016.04.003 · Cited by 30
Anxiety Sensitivity Moderates Prognostic Importance of Rhythm-Control Versus Rate-Control Strategies in Patients With Atrial Fibrillation and Congestive Heart Failure
Frasure‐Smith, N., Lespérance, F., Talajic, M. R., Khairy, P., Dorian, P., O’Meara, E., & Roy, D. (2012) · Circulation Heart Failure · doi:10.1161/circheartfailure.111.964122 · Cited by 27
Left Atrial Reverse Remodeling After Catheter Ablation of Nonparoxysmal Atrial Fibrillation in Patients With Heart Failure With Reduced Ejection Fraction
Oka, T., Inoue, K., Tanaka, K., Ninomiya, Y., Hirao, Y., Tanaka, N., Okada, M., Inoue, H., Nakamaru, R., Koyama, Y., et al. (2018) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2018.03.026 · Cited by 28
Foundation/American Heart Association Task Force on Practice Guidelines Heart Failure in Adults. A Report of the American College of Cardiology Focused Update: ACCF/AHA Guidelines for the Diagnosis and Management of
Ganiats, T. G., Konstam, M. A., MANCINI, D. M., Abraham, W. T., Casey, D. E., Feldman, A. M., & Ma, G. S. (2009) · Cited by 27
Catheter ablation for treatment of patients with atrial fibrillation and heart failure: a meta-analysis of randomized controlled trials
Ma, Y., Bai, F., Qin, F., Li, Y., Tu, T., Sun, C., Zhou, S., & Liu, Q. (2018) · BMC Cardiovascular Disorders · doi:10.1186/s12872-018-0904-3 · Cited by 28
Atrial Fibrillation and Heart Failure: Untangling a Modern Gordian Knot
Skanes, A. C., & TANG, A. S. L. (2018) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2018.07.483 · Cited by 27
Prognostic Impact of Atrial Fibrillation in Acute Myocardial Infarction and Cardiogenic Shock
Feistritzer, H., Desch, S., Zeymer, U., Fuernau, G. F., de Waha‐Thiele, S., Dudek, D., Huber, K., Stępińska, J., Schneider, S., Ouarrak, T., et al. (2019) · Circulation Cardiovascular Interventions · doi:10.1161/circinterventions.118.007661 · Cited by 28
The management of atrial fibrillation in heart failure: an expert panel consensus
Farmakis, D. T., Chrysohoou, C. A., Giamouzis, G., Giannakoulas, G. A., Hamilos, M. I., Naka, K. Κ., Tzeis, S. E., Xydonas, S., Karavidas, A. I., & Parissis, J. (2020) · Heart Failure Reviews · doi:10.1007/s10741-020-09978-0 · Cited by 28
Upstream therapy of atrial fibrillation
Smit, M. D., & Gelder, I. C. V. (2009) · Expert Review of Cardiovascular Therapy · doi:10.1586/erc.09.59 · Cited by 27
Minimally Invasive Delivery of Hydrogel-Encapsulated Amiodarone to the Epicardium Reduces Atrial Fibrillation
García, J. R., Campbell, P. F., Kumar, G., Langberg, J. J., Cesar, L., Deppen, J. N., Shin, E., Bhatia, N. K., Wang, L., Xu, K., et al. (2018) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.118.006408 · Cited by 27
Computational approaches to structural and functional analysis of plastocyanin and other blue copper proteins
Rienzo, F. D., Gabdoulline, R. R., Wade, R. C., Sola, M., & Menziani, M. C. (2004) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-3181-5 · Cited by 27
Atrial fibrillation: better symptom control with rate and rhythm management
Gupta, D., Rienstra, M., Gelder, I. C. V., & Fauchier, L. (2024) · The Lancet Regional Health - Europe · doi:10.1016/j.lanepe.2023.100801 · Cited by 31
Nuevas evidencias, nuevas controversias: análisis crítico de la guía de práctica clínica sobre fibrilación auricular 2010 de la Sociedad Europea de Cardiología
Anguita, M. P., Worner, F., Domenech, P., Marín, F. R., Ortigosa, J., Pérez‐Villacastín, J., Fernández‐Ortíz, A., Alonso, Á., Cequier, A. R., Colet, J. C., et al. (2011) · Revista Española de Cardiología · doi:10.1016/j.recesp.2011.10.003 · Cited by 26
Rapid improvement in left ventricular function after sinus rhythm restoration in patients with idiopathic cardiomyopathy and atrial fibrillation
Müller‐Edenborn, B., Minners, J., Allgeier, J., Burkhardt, T., Lehrmann, H., Ruile, P., Merz, S., Allgeier, M., Neumann, F., Arentz, T., et al. (2019) · EP Europace · doi:10.1093/europace/euz013 · Cited by 26
Benefits of early rhythm control of atrial fibrillation
Eckardt, L., Wolfes, J., & Frommeyer, G. (2023) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2023.04.001 · Cited by 27
Arrhythmias in Dilated Cardiomyopathy
Kumar, S., Stevenson, W. G., & John, R. M. (2015) · Cardiac Electrophysiology Clinics · doi:10.1016/j.ccep.2015.03.005 · Cited by 26
Clinical predictors of atrial fibrillation recurrence in the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico–Atrial Fibrillation (GISSI-AF) trial
Disertori, M., Lombardi, F., Barlera, S., Latini, R., Maggioni, A. P., Zeni, P., Pasquale, G. D., Cosmi, F., & Franzosi, M. G. (2010) · American Heart Journal · doi:10.1016/j.ahj.2010.02.016 · Cited by 26
Cardioversion for Atrial Fibrillation: Treatment Options and Advances
Reiffel, J. A. (2009) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2009.02441.x · Cited by 26
Can we improve outcomes in AF patients by early therapy?
Kirchhof, P. F. (2009) · BMC Medicine · doi:10.1186/1741-7015-7-72 · Cited by 26
Mortality after catheter ablation for atrial fibrillation compared with antiarrhythmic drug therapy. A meta-analysis of randomized trials
Dagres, N., Varounis, C., Flevari, P. G., Piorkowski, C., Bode, K., Rallidis, L. S., Tsougos, E., Leftheriotis, D. I., Sommer, P., Hindricks, G., et al. (2009) · American Heart Journal · doi:10.1016/j.ahj.2009.05.012 · Cited by 26
Rhythm Control in Atrial Fibrillation — One Setback after Another
CAIN, M. E., & Curtis, A. B. (2008) · New England Journal of Medicine · doi:10.1056/nejme0803289 · Cited by 26
Heart failure in the elderly: advances and challenges
Jugdutt, B. I. (2010) · Expert Review of Cardiovascular Therapy · doi:10.1586/erc.10.36 · Cited by 26
Management of atrial fibrillation around the world: a comparison of current ACCF/AHA/HRS, CCS, and ESC guidelines
Wasmer, K., & Eckardt, L. (2011) · EP Europace · doi:10.1093/europace/eur172 · Cited by 25
Comparing the 2010 North American and European Atrial Fibrillation Guidelines
Gillis, A. M., & Skanes, A. C. (2011) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2010.11.009 · Cited by 25
Catheter Ablation Compared with Medical Therapy for Atrial Fibrillation with Heart Failure: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Pan, K., Wu, Y., Lee, M., & Ovbiagele, B. I. (2021) · International Journal of Medical Sciences · doi:10.7150/ijms.52257 · Cited by 25
Cost‐Utility of Catheter Ablation for Atrial Fibrillation in Patients with Heart Failure: An Economic Evaluation
Lau, D., Sandhu, R. K., Andrade, J. G., Ezekowitz, J. A., So, H., & Klarenbach, S. W. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.019599 · Cited by 25
Optimal Rhythm Control Strategy in Patients With Atrial Fibrillation
Kim, D., Yang, P., & Joung, B. (2022) · Korean Circulation Journal · doi:10.4070/kcj.2022.0078 · Cited by 25
Managing Recent-Onset Atrial Fibrillation in the Emergency Department
Stiell, I. G., & Birnie, D. H. (2010) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2010.04.006 · Cited by 25
New Pharmacological Strategies for the Treatment of Atrial Fibrillation
Burashnikov, A., & Antzelevitch, C. N. (2009) · Annals of Noninvasive Electrocardiology · doi:10.1111/j.1542-474x.2009.00305.x · Cited by 25
A randomized trial of budiodarone in paroxysmal atrial fibrillation
For the PASCAL Investigators, Ezekowitz, M. D., Nagarakanti, R., Lubiński, A., Bandman, O., Canafax, D. M., Ellis, D., Milner, P. G., Ziola, M., Thibault, B., et al. (2011) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-011-9636-3 · Cited by 27
Novel use of the ultra-short-acting intravenous β1-selective blocker landiolol for supraventricular tachyarrhythmias in patients with congestive heart failure
Adachi, T., Sato, A., Baba, M., Hiraya, D., Hasegawa, T., Kuroki, K., Hoshi, T., & Aonuma, K. (2013) · Heart and Vessels · doi:10.1007/s00380-013-0377-3 · Cited by 25
Long-term events following atrial fibrillation rate control or transcatheter ablation
Gallo, C., Battaglia, A., Anselmino, M., Bianchi, F., Grossi, S., Nangeroni, G., Toso, E., Gaido, L., Scaglione, M., Ferraris, F., et al. (2015) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0000000000000311 · Cited by 25
Atrial tachyarrhythmia in adult congenital heart disease
Karbassi, A., Nair, K., Harris, L., Wald, R. M., & Roche, S. L. (2017) · World Journal of Cardiology · doi:10.4330/wjc.v9.i6.496 · Cited by 27
Choice and Outcomes of Rate Control versus Rhythm Control in Elderly Patients with Atrial Fibrillation: A Report from the REPOSI Study
REPOSI Investigators, Paciullo, F., Proietti, M., Bianconi, V., Nobili, A., Pirro, M., Mannucci, P. M., Lip, G. Y. H., & Lupattelli, G. (2018) · Drugs & Aging · doi:10.1007/s40266-018-0532-8 · Cited by 25
Impact of Emergency Department Management of Atrial Fibrillation on Hospital Charges
Sacchetti, A. D., Williams, J. A. S., Levi, S. A., & Akula, D. N. (2013) · Western Journal of Emergency Medicine · doi:10.5811/westjem.2012.1.6893 · Cited by 25
Catheter and Surgical Ablation for Atrial Fibrillation
Montané, B., Zhang, S., Wolfe, J. D., Prime, S., Luo, C., Cooper, D. H., Doering, M. M., Blomström‐Lundqvist, C., Nashef, S. A. M., Osmancik, P. P., et al. (2025) · Annals of Internal Medicine · doi:10.7326/annals-25-00253 · Cited by 24
Left atrial mechanics predict the success of pulmonary vein isolation in patients with atrial fibrillation
Spethmann, S., Stüer, K., Diaz, I., Althoff, T. F., Hewing, B., Baumann, G., Dreger, H., & Knebel, F. (2014) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-014-9876-0 · Cited by 25
Meta‐analysis of randomized controlled trials on atrial fibrillation ablation in patients with heart failure with reduced ejection fraction
Smer, A. M., Salih, M., Darrat, Y., Saadi, A., Guddeti, R. R., Haddad, T. M., Kabach, A., Ayan, M., Saurav, A., Abuissa, H. S., et al. (2018) · Clinical Cardiology · doi:10.1002/clc.23068 · Cited by 24
Mobile health-technology integrated care in atrial fibrillation patients with heart failure: A report from the mAFA-II randomized clinical trial
Guo, Y., Romiti, G. F., Corica, B., Proietti, M., Bonini, N., Zhang, H., & Lip, G. Y. H. (2022) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2022.11.002 · Cited by 24
Management of Atrial Fibrillation: Translating Clinical Trial Data into Clinical Practice
Eagle, K. A., Cannom, D. S., & Garcia, D. A. (2010) · The American Journal of Medicine · doi:10.1016/j.amjmed.2010.05.016 · Cited by 24
Rhythm Control Strategies and the Role of Antiarrhythmic Drugs in the Management of Atrial Fibrillation: Focus on Clinical Outcomes
Bunch, T. J., & Gersh, B. J. (2010) · Journal of General Internal Medicine · doi:10.1007/s11606-010-1574-8 · Cited by 24
Prognosis in Patients Hospitalized With Permanent and Nonpermanent Atrial Fibrillation in Heart Failure
Taillandier, S., Bernard, A. B., Lallemand, B., Siméon, E., Pericart, L., Clémenty, N., Babuty, D., & Fauchier, L. (2014) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2013.12.024 · Cited by 24
Impact of restrictive lung disorder on cardiovascular mortality in a general population: The Yamagata (Takahata) study
Honda, Y., Watanabe, T., Shibata, Y., Otaki, Y., Kadowaki, S., Narumi, T., Takahashi, T., Kinoshita, D., Yokoyama, M., Nishiyama, S., et al. (2017) · International Journal of Cardiology · doi:10.1016/j.ijcard.2017.04.049 · Cited by 24
Current Antiarrhythmic Therapy for Nonvalvular Atrial Fibrillation in Spain. Data From the FANTASIIA Registry
Rabadán, I. R., Sánchez, M. A., Marín, F. R., Simón, M. A. Q., Siles, J. C., Peinado, R., Bertoméu, V., Cequier, A. R., Badimón, L., & Muñiz, J. (2015) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2015.03.004 · Cited by 23
Atrial fibrillation in heart failure: The sword of Damocles revisited.
Khan, M., Ahmed, F., Neyses, L., & Mamas, M. (2013) · World Journal of Cardiology · doi:10.4330/wjc.v5.i7.215 · Cited by 21
Emergency medicine considerations in atrial fibrillation
Long, B., Robertson, J., Koyfman, A., Maliel, K., & Warix, J. R. (2018) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2018.01.066 · Cited by 24
Clinical Outcomes of Rate vs Rhythm Control for Atrial Fibrillation in Older People: A Systematic Review and Meta-Analysis
Depoorter, L., Sels, L., Deschodt, M., Grootven, B. V., der Linden, L. R. V., & Tournoy, J. (2019) · Drugs & Aging · doi:10.1007/s40266-019-00722-4 · Cited by 23
Cryoballoon Ablation for the Treatment of Atrial Fibrillation in Patients With Concomitant Heart Failure and Either Reduced or Preserved Left Ventricular Ejection Fraction: Results From the Cryo AF Global Registry
Rordorf, R., Scazzuso, F., Chun, K. R. J., Khelae, S. K., Kueffer, F. J., Braegelmann, K. M., Okumura, K., Al‐Kandari, F., On, Y. K., Földesi, C., et al. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.121.021323 · Cited by 23
Efficacy of Early Catheter Ablation for Atrial Fibrillation After Admission for Heart Failure
Sakamoto, K., Tohyama, T., Ide, T., Mukai, Y., Enzan, N., Nagata, T., Ikeda, M., Takase, S., Nagayama, T., Fujino, T., et al. (2023) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2023.05.038 · Cited by 23
Ion channel trafficking: A new therapeutic horizon for atrial fibrillation
Schumacher, S. M., & Martens, J. R. (2010) · Heart Rhythm · doi:10.1016/j.hrthm.2010.02.017 · Cited by 23
Long-term symptom improvement and patient satisfaction after AV-node ablation vs. pulmonary vein isolation for symptomatic atrial fibrillation: results from the German Ablation Registry
Wasmer, K., Hochadel, M., Wieneke, H., Spitzer, S. G., Brachmann, J., Straube, F., Tebbenjohanns, J., Groschup, G., Heisel, A., Lewalter, T., et al. (2018) · Clinical Research in Cardiology · doi:10.1007/s00392-018-1368-2 · Cited by 24
Digoxin, mortality, and cardiac hospitalizations in patients with atrial fibrillation and heart failure with reduced ejection fraction and atrial fibrillation: An AF-CHF analysis
Elayi, C. S., Shohoudi, A., Moodie, E. E. M., Etaee, F., Guglin, M. E., Roy, D., & Khairy, P. (2020) · International Journal of Cardiology · doi:10.1016/j.ijcard.2020.04.047 · Cited by 24
Compensatory caspase activation in MPP+-induced cell death in dopaminergic neurons
Chee, J. L. Y., Guan, X. L., Lee, J. Y., Dong, B., Leong, S. M., Ong, E. H., Liou, A. K. F., & Lim, T. M. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4413-4 · Cited by 23
Long-term oral anticoagulation for patients after successful catheter ablation of atrial fibrillation
Ha, A. C. T., Hindricks, G., Birnie, D. H., & Verma, A. (2014) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000121 · Cited by 22
Rate or Rhythm Control for Atrial Fibrillation: Update and Controversies
Chinitz, J. S., Halperin, J. L., Reddy, V. Y., & Fuster, V. (2012) · The American Journal of Medicine · doi:10.1016/j.amjmed.2012.04.007 · Cited by 22
Medical treatment of atrial fibrillation
Camm, A. J., Camm, C. F., & Savelieva, I. (2011) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0b013e32834f23e1 · Cited by 22
Modelling the lifetime cost-effectiveness of catheter ablation for atrial fibrillation with heart failure
Gao, L., & Moodie, M. (2019) · BMJ Open · doi:10.1136/bmjopen-2019-031033 · Cited by 22
Atrial arrhythmias in chronic lung disease‐associated pulmonary hypertension
Vahdatpour, C., Luebbert, J. J., & Palevsky, H. I. (2020) · Pulmonary Circulation · doi:10.1177/2045894020910685 · Cited by 22
Atrial fibrillation: the rate versus rhythm management controversy
Aj, C., & Savelieva, I. (2012) · The Journal of the Royal College of Physicians of Edinburgh · doi:10.4997/jrcpe.2012.s03 · Cited by 22
Clinical Outcome in Patients With Paroxysmal or Persistent Atrial Fibrillation Receiving Bepridil
Shiga, T., Suzuki, A., Naganuma, M., Hosaka, F., Shoda, M., & Hagiwara, N. (2011) · Circulation Journal · doi:10.1253/circj.cj-10-1084 · Cited by 22
Mineralocorticoid Receptor Antagonists and Cardiovascular Mortality in Patients With Atrial Fibrillation and Left Ventricular Dysfunction
O’Meara, E., Khairy, P., Chabot-Blanchet, M., de Denus, S., Pedersen, O. D., Lévesque, S., Talajic, M. R., Ducharme, A., White, M., Racine, N., et al. (2012) · Circulation Heart Failure · doi:10.1161/circheartfailure.111.965160 · Cited by 22
Cardioverting acute atrial fibrillation and the risk of thromboembolism: not all patients are created equal
Rankin, A. J., & Rankin, S. H. (2017) · Clinical Medicine · doi:10.7861/clinmedicine.17-5-419 · Cited by 21
Ablation for Atrial Fibrillation in Heart Failure with Reduced Ejection Fraction
Liang, J. J., & Callans, D. J. (2018) · Cardiac failure review · doi:10.15420/cfr.2018:3:1 · Cited by 23
Review of Contemporary Antiarrhythmic Drug Therapy for Maintenance of Sinus Rhythm in Atrial Fibrillation
Singla, S., Karam, P., Deshmukh, A. J., Mehta, J. L., & Paydak, H. (2011) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/1074248410397195 · Cited by 23
Atrial Tachyarrhythmias Among Patients With Left Ventricular Assist Devices
Noll, A. E., Adewumi, J., Amuthan, R., Gillombardo, C. B., Mannan, Z., Kiehl, E. L., Hussein, A. A., Chung, M. K., Wazni, O. M., Starling, R. C., et al. (2019) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2018.11.016 · Cited by 22
Impact of Clinical Characteristics and Management on the Prognosis of Unselected Heart Failure Patients
Eschalier, R., Chenaf, C., Mulliez, A., Yalioua, A., Clerfond, G., Authier, N., Vorilhon, C., Citron, B., Pereira, B., Jean, F., et al. (2015) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-015-6572-y · Cited by 22
Antiarrhythmic Drugs 2013: State of the Art
Kumar, K., & ZIMETBAUM, P. J. (2013) · Current Cardiology Reports · doi:10.1007/s11886-013-0410-2 · Cited by 21
Improved survival in patients with atrial fibrillation and heart failure undergoing catheter ablation compared to medical treatment: A systematic review and meta‐analysis of randomized controlled trials
Romero, J. E., Gabr, M., Alviz, I., Briceno, D. F., Díaz, J. C., Rodríguez, D., Patel, K., Polanco, D., Trivedi, C. G., Mohanty, S., et al. (2022) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.15622 · Cited by 21
Atrial Fibrillation
Trappe, H. (2012) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2012.0001 · Cited by 21
Obesity Paradox and 12 Month Outcome in Patients with Atrial Fibrillation
Rodríguez-Reyes, H., Lara-Vaca, S., Ochoa-Guzmán, A., Chiquete, E., Abundes-Velasco, A., Acevedo-Zepeda, C., Alcocer-Gamba, M. A., Alfaro-Ledesma, Y., Álvarez‐López, H., Álvarez-Mosquera, J. B., et al. (2020) · Archives of Medical Research · doi:10.1016/j.arcmed.2020.10.015 · Cited by 20
This is Your Brain, and This is Your Brain on Atrial Fibrillation: The Roles of Cardiac Malperfusion Events and Vascular Dysfunction in Cognitive Impairment
Zenger, B., Rizzi, S. A., Steinberg, B. A., Ranjan, R., & Bunch, T. J. (2023) · Arrhythmia & Electrophysiology Review · doi:10.15420/aer.2022.29 · Cited by 21
Causal effects between atrial fibrillation and heart failure: evidence from a bidirectional Mendelian randomization study
Zhang, Z., Li, L., Zhao, H., Zhou, L., Zhang, Z., Xiong, Y., & Yao, Y. (2023) · BMC Medical Genomics · doi:10.1186/s12920-023-01606-8 · Cited by 21
Atrial fibrillation, stroke, and quality of life
Chinitz, J. S., Castellano, J. M., Kovacic, J. C., & Fuster, V. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2012.06494.x · Cited by 20
Actualización en cardiología geriátrica
Dı́az-Castro, Ó., Datino, T., López‐Palop, R., & Martínez‐Sellés, M. (2011) · Revista Española de Cardiología · doi:10.1016/s0300-8932(11)70002-1 · Cited by 20
Acute and Chronic Management of Atrial Fibrillation in Patients With Late-Stage CKD
Aronow, W. S. (2009) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2009.01.257 · Cited by 20
Update on the management of atrial fibrillation
Amerena, J. V., Walters, T. E., Mirzaee, S., & Kalman, J. M. (2013) · The Medical Journal of Australia · doi:10.5694/mja13.10191 · Cited by 20
Novel approaches to the management of chronic systolic heart failure: future directions and unanswered questions
Reddy, Y. N. V., Borlaug, B. A., O’Connor, C. M., & Gersh, B. J. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehz364 · Cited by 22
Impact of initial heart failure emergence on clinical outcomes of atrial fibrillation patients in the AFFIRM trial
Slee, A. E., & Saksena, S. V. (2019) · American Heart Journal · doi:10.1016/j.ahj.2019.10.005 · Cited by 20
Prognostic value of atrial fibrillation in patients with heart failure and different left ventricular ejection fraction: results of the multicenter RIF-CHF register
Жиров, И. В., Safronova, N. V., Osmolovskaya, Y. F., & Тereschenko, S. N. (2021) · Russian Journal of Cardiology · doi:10.15829/1560-4071-2021-4200 · Cited by 20
Clinical U pdate on the M anagement of A trial F ibrillation
Danelich, I. M., Reed, B. N., Hollis, I. B., Cook, A. M., & Rodgers, J. E. (2013) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.1217 · Cited by 21
How to manage various arrhythmias and sudden cardiac death in the cardiovascular intensive care
Kobayashi, Y. (2018) · Journal of Intensive Care · doi:10.1186/s40560-018-0292-x · Cited by 20
Cardiac arrhythmias in congestive heart failure
Kantharia, B. K. (2010) · Expert Review of Cardiovascular Therapy · doi:10.1586/erc.09.185 · Cited by 19
Classification and choice of antiarrhythmic therapies
Barton, A. K., McGowan, M., Smyth, A., Wright, G. A., & Gardner, R. S. (2020) · Prescriber · doi:10.1002/psb.1828 · Cited by 19
Sex-Specific Prevalence, Incidence, and Mortality Associated With Atrial Fibrillation in Heart Failure
Barillas-Lara, M. I., Monahan, K. M., Helm, R. H., Vasan, R. S., Schou, M., Køber, L., Gislason, G., Torp-Pedersen, C. T., & Andersson, C. (2021) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2021.02.021 · Cited by 19
Low ambient temperature increases the risk and burden of atrial fibrillation episodes: A nationwide case-crossover study in 322 Chinese cities
Zhu, X., Chen, R., Zhang, Y., Hu, J., Jiang, Y., Huang, K., Wang, J., Li, W., Shi, B., Chen, Y., et al. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.163351 · Cited by 19
Atrial Fibrillation and Heart Failure: Cause or Effect?
Luong, C. L., Barnes, M. E., & Tsang, T. S. M. (2014) · Current Heart Failure Reports · doi:10.1007/s11897-014-0229-1 · Cited by 19
Arrhythmias in Structural Heart Disease
Gillespie, H. S., Lin, C. C. H., & Prutkin, J. M. (2014) · Current Cardiology Reports · doi:10.1007/s11886-014-0510-7 · Cited by 18
Comparison of Rate Control versus Rhythm Control for Management of Atrial Fibrillation in Patients with Coexisting Heart Failure: A Cost‐Effectiveness Analysis
Pérez, A., Touchette, D. R., DiDomenico, R. J., Stamos, T. D., & Walton, S. M. (2011) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.31.6.552 · Cited by 19
Catheter ablation of atrial fibrillation in the elderly: does the benefit outweigh the risk?
Kennedy, R. T., & Oral, H. (2013) · Expert Review of Cardiovascular Therapy · doi:10.1586/erc.13.2 · Cited by 19
Atrial Fibrillation: Goals of Therapy and Management Strategies to Achieve the Goals
Padanilam, B. J., & Prystowsky, E. N. (2008) · Cardiology Clinics · doi:10.1016/j.ccl.2008.09.006 · Cited by 19

Authors: Roy, D., Talajic, M., Nattel, S., Wyse, D. G., Dorian, P., Lee, K. L., Bourassa, M. G., Arnold, J. M. O., Buxton, A. E., Camm, A. J., Connolly, S. J., Dubuc, M., Ducharme, A., Guerra, P. G., Hohnloser, S. H., Lambert, J., Le Heuzey, J.-Y., O'Hara, G., Pedersen, O. D., Rouleau, J.-L., Singh, B. N., Stevenson, L. W., Stevenson, W. G., Thibault, B., & Waldo, A. L.
Affiliations: Montreal Heart Institute (CA)
Libin Cardiovascular Institute of Alberta (CA)
St. Michael's Hospital (CA)
Duke Medical Center (US)
London Health Sciences Centre (CA)
Rhode Island Hospital (US)
St George's Hospital (GB)
Population Health Research Institute (CA)
Goethe University Frankfurt (DE)
Bispebjerg Hospital (DK)
VA West Los Angeles Medical Center (US)
Brigham and Women's Hospital (US)
University Hospitals Cleveland Medical Center (US)
ORCID: Roy, Denis
Talajic, Mario
Nattel, Stanley
Dorian, Paul
Bourassa, Martial G.
Buxton, Alfred E.
Camm, A. John
Connolly, Stuart J.
Ducharme, Anique
Guerra, Peter G.
Hohnloser, Stefan H.
Lambert, Jean
Pedersen, Ole Dyg
Rouleau, Jean-Lucien
Stevenson, Lynne Warner
Stevenson, William G.
Thibault, Bernard
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2008-06-19
Volume: 358
Issue: 25
Pages: 2667-2677
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmoa0708789
OpenAlex: W2131260805
Cited by: 1,585
References: 41
Citations by year: 2026: 42 · 2025: 33 · 2024: 69 · 2023: 55 · 2022: 76 · 2021: 86 · 2020: 77 · 2019: 82 · 2018: 96 · 2017: 87 · 2016: 73 · 2015: 75 · 2014: 87 · 2013: 123 · 2012: 114
FWCI: 97.76
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B)) (submittedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
Keywords: atrial fibrillation, heart failure, rhythm control, rate control, sinus rhythm maintenance, ventricular rate control, cardiovascular mortality, congestive heart failure, stroke, worsening heart failure, left ventricular ejection fraction
MeSH terms: Adrenergic beta-Antagonists, Aged, Amiodarone, Angiotensin-Converting Enzyme Inhibitors, Anti-Arrhythmia Agents, Atrial Fibrillation, Cardiovascular Diseases, Combined Modality Therapy, Digitalis Glycosides, Electric Countershock, Female, Follow-Up Studies, Heart Failure, Heart Rate, Hospitalization, Humans, Male, Middle Aged, Prospective Studies, Ventricular Dysfunction, Left, Kaplan-Meier Estimate

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Rhythm Control versus Rate Control for Atrial Fibrillation and Heart Failure

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks