Modulation of Blood Pressure by Central Melanocortinergic Pathways

Cited by (490)

Items 201–300 of 490

1. Monogenic Obesity; Using Drugs to Bypass the Problem
   Anthony P. Coll · 2018 · Cell Metabolism
2. Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice
   Benjamin P. Tooke, Hui Min Yu, Jessica M. Adams, Graham L. Jones, Talisha Sutton-Kennedy, Lakshmi V. Mundada, Nathan Qi, Malcolm James Low, Kavaljit H. Chhabra · 2018 · Molecular Metabolism
3. Effects of AgRP Inhibition on Energy Balance and Metabolism in Rodent Models
   Roxanne Dutia, Andrea J. Kim, Matthew E. Modes, Robert Rothlein, Jane M. Shen, Ye Tian, Jumana Ihbais, Sam F. Victory, Carmen Valcarce, Sharon L. Wardlaw · 2013 · PLoS ONE
4. Obesity, Metabolic Syndrome and Disorders of Energy Balance
   Joan C. Han, Ram Weiss · 2021 · Elsevier eBooks
5. Temporal cAMP Signaling Selectivity by Natural and Synthetic MC4R Agonists
   Brent Molden, Kimberly A. Cooney, Kirk L. West, Lex H.T. Van der Ploeg, Giulia Baldini · 2015 · Molecular Endocrinology
6. Prolyl carboxypeptidase and its inhibitors in metabolism
   Jin Kwon Jeong, Sabrina Diano · 2012 · Trends in Endocrinology and Metabolism
7. Inhibition of the central melanocortin system decreases brown adipose tissue activity
   Sander Kooijman, Mariëtte R. Boon, Edwin T. Parlevliet, Janine J. Geerling, Vera van de Pol, Johannes Anthonius Romijn, Louis M. Havekes, Illiana Meurs, Patrick C.N. Rensen · 2014 · Journal of Lipid Research
8. Differentiating monogenic and syndromic obesities from polygenic obesity: Assessment, diagnosis, and management
   Angela Fitch, Sonali Malhotra, Rushika Conroy · 2024 · Obesity Pillars
9. Ac-Trp-DPhe(p-I)-Arg-Trp-NH2, a 250-Fold Selective Melanocortin-4 Receptor (MC4R) Antagonist over the Melanocortin-3 Receptor (MC3R), Affects Energy Homeostasis in Male and Female Mice Differently
   Cody J. Lensing, Danielle N. Adank, Skye R. Doering, Stacey L. Wilber, Amy M. Andreasen, Jay W. Schaub, Zhimin Xiang, Carrie Haskell‐Luevano · 2016 · ACS Chemical Neuroscience
10. Obesity‐associated mutant melanocortin‐4 receptors with normal Gαs coupling frequently exhibit other discoverable pharmacological and biochemical defects
    Taneisha R. Gillyard, Katelyn Fowler, Savannah Y. Williams, Roger D. Cone · 2019 · Journal of Neuroendocrinology
11. Modulation of blood pressure by central melanocortinergic pathways
    T. Maier, Joachim D. Hoyer · 2010 · Nephrology Dialysis Transplantation
12. Discovery of Novel Potent and Selective Agonists at the Melanocortin-3 Receptor
    Alfonso Carotenuto, Francesco Merlino, Minying Cai, Diego Brancaccio, Ali Munaim Yousif, Ettore Novellino, Victor J. Hruby, Paolo Grieco · 2015 · Journal of Medicinal Chemistry
13. Pharmacotherapy in Childhood Obesity
    Peter Kühnen, Heike Biebermann, Susanna Wiegand · 2021 · Hormone Research in Paediatrics
14. The metabolic syndrome in older persons: a loosely defined constellation of symptoms or a distinct entity?
    John Edward Morley, Alan J. Sinclair · 2009 · Age and Ageing
15. Possible Mechanism of Spinal T9 StimulationInduced Acute Renal Failure: A Virally Mediated Transsynaptic Tracing Study in Transgenic Mouse Model
    Hong‐Bing Xiang · 2013 · Pain Physician
16. Click-Chemistry-Mediated Synthesis of Selective Melanocortin Receptor 4 Agonists
    Daniel Palmer, Juliana Pereira Lopes Gonçalves, Louise V. Hansen, Boqian Wu, Helle Hald, Sanne Schoffelen, Frederik Diness, Sebastian T. Le Quement, Thomas E. Nielsen, Morten Meldal · 2017 · Journal of Medicinal Chemistry
17. Sex Differences in Leptin Control of Cardiovascular Function in Health and Metabolic Diseases
    Eric J. Belin de Chantemèle · 2017 · Advances in experimental medicine and biology
18. Developing a Biased Unmatched Bivalent Ligand (BUmBL) Design Strategy to Target the GPCR Homodimer Allosteric Signaling (cAMP over β-Arrestin 2 Recruitment) Within the Melanocortin Receptors
    Cody J. Lensing, Katie T. Freeman, Sathya M. Schnell, Robert Charles Speth, Adam T. Zarth, Carrie Haskell‐Luevano · 2018 · Journal of Medicinal Chemistry
19. Investigational drugs in Phase II clinical trials for the treatment of obesity: implications for future development of novel therapies
    V. Margaret Jackson, David A. Price, Philip A. Carpino · 2014 · Expert Opinion on Investigational Drugs
20. Enhanced blood pressure and appetite responses to chronic central melanocortin-3/4 receptor blockade in dietary-induced obesity
    John Harvey Dubinion, Alexandre A. da Silva, John Edward Hall · 2010 · Journal of Hypertension
21. Manifestation of renal disease in obesity: pathophysiology of obesity-related dysfunction of the kidney
    Larry A. Weinrauch, Manish R. Maski · 2009 · International Journal of Nephrology and Renovascular Disease
22. Activation of the melanocortin-4 receptor causes enhanced excitation in presympathetic paraventricular neurons in obese Zucker rats
    Zengyou Ye, De‐Pei Li · 2010 · Regulatory Peptides
23. Mrap2: An Accessory Protein Linked to Obesity
    Tiemin Liu, Joel Keith Elmquist, Kevin W. Williams · 2013 · Cell Metabolism
24. Melanocortin-4 receptor expression in the rostral ventromedial medulla involved in modulation of nociception in transgenic mice
    Xu-chu Pan, Yong-tang Song, Cheng Liu, Hong‐Bing Xiang, Chuanjian Lu · 2013 · Journal of Huazhong University of Science and Technology [Medical Sciences]
25. Molecular Therapy of Melanocortin-4-Receptor Obesity by an Autoregulatory BDNF Vector
    Jason J. Siu, Nicholas J. Queen, Xianglan Liu, Wei Huang, Travis B. McMurphy, Lei Cao · 2017 · Molecular Therapy — Methods & Clinical Development
26. Melanocortin-4 receptor regulation of pain
    Zhixiao Li, Baowen Liu, Zhigang He, Hong‐Bing Xiang · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
27. The Melanocortin 4 Receptor p.Ile269Asn Mutation Is Associated with Childhood and Adult Obesity in Mexicans
    Miguel Alexander Vázquez‐Moreno, Helen Zeng, Daniel Locia‐Morales, Jesús Peralta‐Romero, Hamza Asif, Arjuna Maharaj, Vivian Tam, María del Socorro Romero-Figueroa, Gloria Patricia Sosa-Bustamante, Socorro Méndez‐Martínez et al. · 2019 · The Journal of Clinical Endocrinology & Metabolism
28. Melanocortin agonists stimulate lipolysis in human adipose tissue explants but not in adipocytes
    Møller, Cathrine Laustrup, Pedersen, Steen B., Richelsen, Bjørn, Conde-Frieboes, Kilian W., Raun, Kirsten, Grove, Kevin L., Wulff, Birgitte Schjellerup · 2015 · BMC Research Notes
29. Pharmacological chaperone action in humanized mouse models of MC4R-linked obesity
    Patricia René, Damien Lanfray, Denis Richard, Michel Bouvier · 2021 · JCI Insight
30. The central melanocortin system as a treatment target for obesity and diabetes: A brief overview
    Rajesh Kumar Goit, Andrew W. Taylor, Acy Lo · 2022 · European Journal of Pharmacology
31. Melanocortin MC4 receptor expression sites and local function
    Jacqueline E Siljee-Wong · 2011 · European Journal of Pharmacology
32. Stimulation of the pedunculopontine tegmental nucleus may affect renal function by melanocortinergic signaling
    Cheng Liu, Dawei Ye, Xuehai Guan, Rong-Chun Li, Hongbing Xiang, Wenzhen Zhu · 2013 · Medical Hypotheses
33. Bombesin-like receptor 3 regulates blood pressure and heart rate via a central sympathetic mechanism
    Dalya M. Lateef, Cuiying Xiao, Robert J. Brychta, André Diedrich, Jurgen B. Schnermann, Marc L. Reitman · 2016 · American Journal of Physiology-Heart and Circulatory Physiology
34. Role of the renin-angiotensin system in the development of severe COVID-19 in hypertensive patients
    Rodrigo Pacheco Silva-Aguiar, Diogo B. Peruchetti, Patrícia R. M. Rocco, Alvin H. Schmaier, Patrı́cia Silva, Marco Aurélio Martins, Vinícius Frias Carvalho, Ana Acácia S. Pinheiro, Celso Caruso‐Neves · 2020 · American Journal of Physiology-Lung Cellular and Molecular Physiology
35. Successful Treatment with Atomoxetine of an Adolescent Boy with Attention Deficit/Hyperactivity Disorder, Extreme Obesity, and Reduced Melanocortin 4 Receptor Function
    Wilfried Pott, Özgür Albayrak, Anke Hinney, Johannes Hebebrand, Ursula Pauli‐Pott · 2013 · Obesity Facts
36. Melanocortin‐4 receptor expression in different classes of spinal and vagal primary afferent neurons in the mouse
    Laurent Gautron, Charlotte E. Lee, Syann Lee, Joel Keith Elmquist · 2012 · The Journal of Comparative Neurology
37. Ligands for Melanocortin Receptors: Beyond Melanocyte-Stimulating Hormones and Adrenocorticotropin
    Xiao‐Chen Yuan, Ya‐Xiong Tao · 2022 · Biomolecules
38. Genetic testing in patients with obesity
    Franziska Phan-Hug, Jacques Samuel Beckmann, Sébastien Jacquemont · 2012 · Best Practice & Research Clinical Endocrinology & Metabolism
39. Brain-mediated antidiabetic, anorexic, and cardiovascular actions of leptin require melanocortin-4 receptor signaling
    Alexandre A. da Silva, Frank Travis Spradley, Joey P. Granger, John Edward Hall, Jussara Marcia do Carmo · 2015 · Journal of Neurophysiology
40. Melanocortin Antagonist Tetrapeptides with Minimal Agonist Activity at the Mouse Melanocortin-3 Receptor
    Skye R. Doering, Aleksandar Todorović, Carrie Haskell‐Luevano · 2014 · ACS Medicinal Chemistry Letters
41. Tirzepatide leads to weight reduction in people with obesity due to MC4R deficiency
    Bhatnagar, Pallav, Ahmad, Nadia N., Li, Xuan, Coghlan, Matthew, Kaplan, Lee M., Farooqi, I. Sadaf · 2025 · Nature Medicine
42. Autonomic Nervous System Dysregulation in Pediatric Hypertension
    Janusz Feber, Marcel Ruzicka, Pavel Geier, Mieczysław Litwin · 2014 · Current Hypertension Reports
43. Regulation of Lean Mass, Bone Mass, and Exercise Tolerance by the Central Melanocortin System
    Theodore P. Braun, Benjamin Orwoll, Xinxia Zhu, Peter R. Levasseur, Marek Szumowski, My Linh Nguyen, Mary Bouxsein, Robert F. Klein, Daniel L. Marks · 2012 · PLoS ONE
44. The renin–angiotensin system in the arcuate nucleus controls resting metabolic rate
    Guorui Deng, Justin L. Grobe · 2018 · Current Opinion in Nephrology & Hypertension
45. MC4R Single Nucleotide Polymorphisms Were Associated with Metabolically Healthy and Unhealthy Obesity in Chinese Northern Han Populations
    Luying Gao, Linjie Wang, Hongbo Yang, Hui Pan, Fengying Gong, Huijuan Zhu · 2019 · International Journal of Endocrinology
46. γ2-Melanocyte stimulation hormone (γ2-MSH) truncation studies results in the cautionary note that γ2-MSH is not selective for the mouse MC3R over the mouse MC5R
    Christine G. Joseph, Hua Yao, Joseph W. Scott, Nicholas B. Sorensen, Rebecca N. Marnane, Kathleen Grace Mountjoy, Carrie Haskell‐Luevano · 2010 · Peptides
47. Hypothalamic melanocortin signaling and leptin resistance—Perspective of therapeutic application for obesity-diabetes syndrome
    Hiroaki Masuzaki, Tomohiro Tanaka, Ken Ebihara, Kiminori Hosoda, Kazuwa Nakao · 2009 · Peptides
48. Does leptin cause an increase in blood pressure in animals and humans?
    Stephanie E. Simonds, Jack T. Pryor, Michael Alexander Cowley · 2016 · Current Opinion in Nephrology & Hypertension
49. Obesity due to MC4R deficiency is associated with reduced cholesterol, triglycerides and cardiovascular disease risk
    Stefanie Zorn, Rebecca Bounds, Alice Williamson, Katherine Lawler, Ruth Hanßen, Julia M. Keogh, Elana Henning, Miriam Smith, Barbara A. Fielding, Anne Margot Umpleby et al. · 2025 · Nature Medicine
50. Pathophysiology of primary hypertension in children and adolescents
    Mieczysław Litwin · 2023 · Pediatric Nephrology
51. Hypogonadotropic Hypogonadism in a Homozygous MC4R Mutation Carrier and the Effect of Sibutramine Treatment on Body Weight and Obesity-Related Health Risks
    Irena Aldhoon Hainerová, Hana Zamrazilová, Dana Sedláčková, Vojtěch Hainer · 2011 · Obesity Facts
52. Chronic Central Nervous System MC3/4R Blockade Attenuates Hypertension Induced by Nitric Oxide Synthase Inhibition but Not by Angiotensin II Infusion
    da Silva, Alexandre A., do Carmo, Jussara M., Dubinion, John H., Bassi, Mirian, Mokhtarpouriani, Kasra, Hamza, Shereen M., Hall, John E. · 2015 · Hypertension
53. New perspectives on the origin of hypertension; the role of the hypothalamic melanocortin system
    Anne‐Maj Samuelsson · 2014 · Experimental Physiology
54. Endogenous cannabinoids are required for MC4R-mediated control of energy homeostasis
    Yu Yong, Işın Çakır, Pauline Lining Pan, Jessica E. Biddinger, Rebecca J. Bluett, Ken Mackie, Nathan C. Bingham, Sachin H Patel, Masoud Ghamari‐Langroudi · 2021 · Proceedings of the National Academy of Sciences
55. MicroRNA-7 regulates melanocortin circuits involved in mammalian energy homeostasis
    Mary P. LaPierre, Katherine Lawler, Svenja Godbersen, I. Sadaf Farooqi, Markus Stoffel · 2022 · Nature Communications
56. Medical semiology of patients with monogenic obesity: A systematic review
    Émeline Renard, Ariane Thevenard-Berger, David Meyre · 2024 · Obesity Reviews
57. Vascular effects of deletion of melanocortin-4 receptors in rats
    David W. Stepp, Christabell C. Osakwe, Eric J. Belin de Chantemèle, JAMES D. MINTZ · 2013 · Physiological Reports
58. The Metabolic Syndrome in Older Persons
    Alan J. Sinclair, Adie Viljoen · 2010 · Clinics in Geriatric Medicine
59. Incorporation of a Bioactive Reverse-Turn Heterocycle into a Peptide Template Using Solid-Phase Synthesis To Probe Melanocortin Receptor Selectivity and Ligand Conformations by 2D 1H NMR
    Anamika Singh, Andrzej M. Wilczynski, Jerry Ryan Holder, Rachel M. Witek, Marvin L. S. Dirain, Zhimin Xiang, Arthur S. Edison, Carrie Haskell‐Luevano · 2011 · Journal of Medicinal Chemistry
60. A Macrocyclic Agouti-Related Protein/[Nle4,DPhe7]α-Melanocyte Stimulating Hormone Chimeric Scaffold Produces Subnanomolar Melanocortin Receptor Ligands
    Mark D. Ericson, Katie T. Freeman, Sathya M. Schnell, Carrie Haskell‐Luevano · 2017 · Journal of Medicinal Chemistry
61. Systemic but not central nervous system nitric oxide synthase inhibition exacerbates the hypertensive effects of chronic melanocortin-3/4 receptor activation
    do Carmo, Jussara M., Bassi, Mirian, da Silva, Alexandre A., Hall, John E. · 2011 · Hypertension
62. Delineation of the central melanocortin circuitry controlling the kidneys by a virally mediated transsynaptic tracing study in transgenic mouse model
    Tao Tao Liu, Bao Wen Liu, Zhi Gang He, Feng Li, San Guang Liu, Hong Bing Xiang · 2016 · Oncotarget
63. A Gut-Intrinsic Melanocortin Signaling Complex Augments L-Cell Secretion in Humans
    Emily W. L. Sun, Eva Winning Iepsen, Nektaria Pezos, Amanda L. Lumsden, Alyce M. Martin, Gudrun Schober, Nichole J. Isaacs, Christopher Keith Rayner, Nam Quoc Nguyen, Dayan de Fontgalland et al. · 2021 · Gastroenterology
64. The melanocortin‐4 receptor pathway and the emergence of precision medicine in obesity management
    Sima Fansa, Andres J Acosta · 2024 · Diabetes Obesity and Metabolism
65. The Role of Sympatho-Inhibition in Combination Treatment of Obesity-Related Hypertension
    Revathy Carnagarin, Cynthia Gregory, Omar Azzam, Graham S. Hillis, Carl Johann Schultz, Gerald Francis Watts, Damon A. Bell, Vance Bruce Matthews, Markus Peter Schlaich · 2017 · Current Hypertension Reports
66. Leptin and Associated Neural Pathways Underlying Obesity‐Induced Hypertension
    Connor F. Laule, Kamal Rahmouni · 2024 · Comprehensive physiology
67. Melanocortin 4 receptor stimulation prevents antidepressant-associated weight gain in mice caused by long-term fluoxetine exposure
    María José Ortuño, Marc Schneeberger, Anoj Ilanges, François Marchildon, Kyle Pellegrino, Jeffrey M. Friedman, Patricia Ducy · 2021 · Journal of Clinical Investigation
68. Leptin in Association With Common Variants of MC3R Mediates Hypertension
    Osama A Alsmadi, Motasem Melhem, Prashantha Hebbar, Gaurav Thareja, Sumi Elsa John, Fadi Alkayal, Kazem Behbehani, Thangavel Alphonse Thanaraj · 2014 · American Journal of Hypertension
69. Robust Reductions of Excess Weight and Hyperphagia by Beloranib in Rat Models of Genetic and Hypothalamic Obesity
    Clinton Elfers, Christian Ludwig Roth · 2016 · Endocrinology
70. Molecular Mechanisms of Sodium-Sensitive Hypertension in the Metabolic Syndrome
    Jonathan M. Nizar, Vivek Bhalla · 2017 · Current Hypertension Reports
71. Treatment of Cachexia
    Jeremy R. Steinman, Mark Daniel DeBoer · 2013 · Vitamins and hormones
72. Obesity Drug Update: The Lost Decade?
    Fayi Yao, Robert G. MacKenzie · 2010 · Pharmaceuticals
73. Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy
    Michael J Litt, Gosife Donald Okoye, Daniel Stephen Lark, Işın Çakır, Christy S. Moore, Mary Barber, James B. Atkinson, Joshua P. Fessel, Javid J. Moslehi, Roger D. Cone · 2017 · eLife
74. Cardiometabolic crosstalk in obesity-associated arterial hypertension
    Jens Jordan, Andreas L. Birkenfeld · 2016 · Reviews in Endocrine and Metabolic Disorders
75. Obesity Before Birth
    Robert H. Lustig · 2010 · Endocrine updates
76. Eating behaviour in contrasting adiposity phenotypes: Monogenic obesity and congenital generalized lipodystrophy
    José Luis Santos, Vı́ctor Cortés · 2020 · Obesity Reviews
77. Pharmacologic Weight Management in the Era of Adolescent Obesity
    Vandana S. Raman, Anshu Gupta, Ambika P. Ashraf, Emily Breidbart, Evgenia Gourgari, Manmohan K. Kamboj, Brenda Kohn, Sowmya Krishnan, Amit Lahoti, Kristal Anne Matlock et al. · 2022 · The Journal of Clinical Endocrinology & Metabolism
78. Metabolic Precision Medicines: Curing POMC Deficiency
    Timo D. Müller, Matthias H. Tschöp, Stephen O’Rahilly · 2016 · Cell Metabolism
79. Mutations in melanocortin-4 receptor: From fish to men
    Ya‐Xiong Tao · 2022 · Progress in molecular biology and translational science
80. Low resting metabolic rate and increased hunger due to β-MSH and β-endorphin deletion in a canine model
    Marie Theres Dittmann, Gabriella Lakatos, Jodie F. Wainwright, Jacek Mokrosiński, Eloise Cross, I. Sadaf Farooqi, Natalie Jessica Wallis, Lewis George Halsey, Rory Paul Wilson, Stephen O’Rahilly et al. · 2024 · Science Advances
81. The Influence of the Sympathetic Nervous System on Cardiometabolic Health in Response to Weight Gain or Weight Loss
    Gavin William Lambert, Mariya Patel, Élisabeth Lambert · 2025 · Metabolites
82. Pathophysiology and Potential Non-Pharmacologic Treatments of Obesity or Kidney Disease Associated Refractory Hypertension
    Thierry H. Le Jemtel, William Richardson, Rohan Samson, Abhishek Jaiswal, Suzanne Oparil · 2017 · Current Hypertension Reports
83. Role of melanocortin 4 receptor in hypertension induced by chronic intermittent hypoxia
    Jussara Marcia do Carmo, Alexandre A. da Silva, Sydney P. Moak, Fernanda S. da Silva, Frank Travis Spradley, John Edward Hall · 2018 · Acta Physiologica
84. Metabolic Syndrome
    Matthew Bruce Lanktree, Robert Alexander Hegele · 2017 · Elsevier eBooks
85. Rolling out physical exercise and energy homeostasis: Focus on hypothalamic circuitries
    João Paulo Cavalcanti‐de‐Albuquerque, José Donato · 2021 · Frontiers in Neuroendocrinology
86. MC4R biased signalling and the conformational basis of biological function selections
    Zekun Liu, Victor J. Hruby · 2022 · Journal of Cellular and Molecular Medicine
87. An evaluation of setmelanotide injection for chronic weight management in adult and pediatric patients with obesity due to Bardet–Biedl syndrome
    Julia Lazareva, Sheila M. Brady, Jack Adam Yanovski · 2023 · Expert Opinion on Pharmacotherapy
88. Hemodynamic actions and mechanisms of systemically administered α-MSH analogs in mice
    Petteri Rinne, Sanna Tikka, Satu Mäkelä, Tomi Streng, Eriika Savontaus · 2012 · Peptides
89. SOCS3 Ablation in Leptin Receptor-Expressing Cells Causes Autonomic and Cardiac Dysfunctions in Middle-Aged Mice despite Improving Energy and Glucose Metabolism
    João A.B. Pedroso, Ivson B. da Silva, Thais T. Zampieri, Leonardo Tedesco Totola, Thiago Santos Moreira, Ana Paula Tiemi Taniguti, Gabriela Placoná Diniz, Maria Luiza Morais Barreto‐Chaves, José Donato · 2022 · International Journal of Molecular Sciences
90. Setmelanotide: A Melanocortin-4 Receptor Agonist for the Treatment of Severe Obesity Due to Hypothalamic Dysfunction
    Sulmaaz Qamar, Ritwika Mallik, Janine Makaronidis · 2024 · touchREVIEWS in Endocrinology
91. Prevalence of metabolic syndrome in obese Chilean children and association with gene variants of the leptin-melanocortin system
    José Suazo, María Isabel Hodgson, Ana María Obregón, Macarena Valladares, Gerardo Weisstaub N., Paola Amador, José Luis Santos · 2013 · Journal of Pediatric Endocrinology and Metabolism
92. Effects of the POMC System on Glucose Homeostasis and Potential Therapeutic Targets for Obesity and Diabetes
    Dan Yang, Xintong Hou, Guimei Yang, Mengnan Li, Jian Zhang, Minmin Han, Yi Zhang, Yunfeng Liu · 2022 · Diabetes Metabolic Syndrome and Obesity
93. Structure–Activity Relationships of Peptides Incorporating a Bioactive Reverse-Turn Heterocycle at the Melanocortin Receptors: Identification of a 5800-fold Mouse Melanocortin-3 Receptor (mMC3R) Selective Antagonist/Partial Agonist versus the Mouse Melanocortin-4 Receptor (mMC4R)
    Anamika Singh, Marvin L. S. Dirain, Rachel M. Witek, James R. Rocca, Arthur S. Edison, Carrie Haskell‐Luevano · 2013 · Journal of Medicinal Chemistry
94. Sympathetic Activation in Resistant Hypertension: Theory and Therapy
    Raymond Oliva, George L. Bakris · 2014 · Seminars in Nephrology
95. Obesity due to melanocortin 4 receptor (MC4R) deficiency is associated with delayed gastric emptying
    Eleonora Seelig, Elana Henning, Julia M. Keogh, Daniel Gillett, Evelyn Shin, John Richard Buscombe, Agatha A. van der Klaauw, I. Sadaf Farooqi · 2021 · Clinical Endocrinology
96. Discrete melanocortin-sensitive neuroanatomical pathway linking the ventral premmamillary nucleus to the paraventricular hypothalamus
    L. Gautron, Roberta M. Cravo, Joel Keith Elmquist, Carol Fuzeti Elias · 2013 · Neuroscience
97. Effect of Age on Interdependence and Hierarchy of Cardiovascular Risk Factors in Hypertensive Patients
    Gregory P. Vyssoulis, E. Karpanou, Dionysios N. Adamopoulos, V. Tzamou, Christodoulos Stefanadis, Ulrich M. Vischer · 2011 · The American Journal of Cardiology
98. Effect of Body Weight Change on Blood Pressure in a Japanese General Population with a Body Mass Index ≥ 22 kg/m2
    Hidetaka Itoh, Hidehiro Kaneko, Hiroyuki Kiriyama, Koki Nakanishi, Yoshiko Mizuno, Masao Daimon, Hiroyuki Morita, Nobutake Yamamichi, Issei Komuro · 2019 · International Heart Journal
99. Melanocortin-4 receptors activate sympathetic preganglionic neurons and elevate blood pressure via TRPV1
    Sang Hyeon Ju, Hyeonju Yun, Youjin Oh, Yeeun Choi, Jong‐Woo Sohn · 2022 · Cell Reports
100. RISING STARS: Targeting G protein-coupled receptors to regulate energy homeostasis
     Aqfan Jamaluddin, Caroline M. Gorvin · 2023 · Journal of Molecular Endocrinology