Cited by 3,157Cardiac pacing and defibrillation studiesCardiac Arrest and ResuscitationCardiac Health and Mental Health

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

Cardiac-Resynchronization Therapy for the Prevention of Heart-Failure Events

Moss, Arthur J., Hall, W. Jackson, Cannom, David S., Klein, Helmut, Brown, Mary W., Daubert, James P., Estes, N.A. Mark, Foster, Elyse, Greenberg, Henry, Higgins, Steven L., Pfeffer, Marc A., Solomon, Scott D., Wilber, David, Zareba, Wojciech·2009·New England Journal of Medicine

DOI 10.1056/nejmoa0906431

Open this paper in CoChat — free account

Abstract

BACKGROUND: This trial was designed to determine whether cardiac-resynchronization therapy (CRT) with biventricular pacing would reduce the risk of death or heart-failure events in patients with mild cardiac symptoms, a reduced ejection fraction, and a wide QRS complex. METHODS: During a 4.5-year period, we enrolled and followed 1820 patients with ischemic or nonischemic cardiomyopathy, an ejection fraction of 30% or less, a QRS duration of 130 msec or more, and New York Heart Association class I or II symptoms. Patients were randomly assigned in a 3:2 ratio to receive CRT plus an implantable cardioverter-defibrillator (ICD) (1089 patients) or an ICD alone (731 patients). The primary end point was death from any cause or a nonfatal heart-failure event (whichever came first). Heart-failure events were diagnosed by physicians who were aware of the treatment assignments, but they were adjudicated by a committee that was unaware of assignments. RESULTS: During an average follow-up of 2.4 years, the primary end point occurred in 187 of 1089 patients in the CRT-ICD group (17.2%) and 185 of 731 patients in the ICD-only group (25.3%) (hazard ratio in the CRT-ICD group, 0.66; 95% confidence interval [CI], 0.52 to 0.84; P=0.001). The benefit did not differ significantly between patients with ischemic cardiomyopathy and those with nonischemic cardiomyopathy. The superiority of CRT was driven by a 41% reduction in the risk of heart-failure events, a finding that was evident primarily in a prespecified subgroup of patients with a QRS duration of 150 msec or more. CRT was associated with a significant reduction in left ventricular volumes and improvement in the ejection fraction. There was no significant difference between the two groups in the overall risk of death, with a 3% annual mortality rate in each treatment group. Serious adverse events were infrequent in the two groups. CONCLUSIONS: CRT combined with ICD decreased the risk of heart-failure events in relatively asymptomatic patients with a low ejection fraction and wide QRS complex. (ClinicalTrials.gov number, NCT00180271.)

Integrity signals

Registry

Crossref · 10.1056/nejmoa0906431

Cites

17 of 17 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Regression Models and Life-Tables
Cox, D. R. (1972) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1972.tb00899.x · Cited by 39,793
Recommendations for Chamber Quantification: A Report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, Developed in Conjunction with the European Association of Echocardiography, a Branch of the European Society of Cardiology
Lang, R. M., Bierig, M., Devereux, R. B., Flachskampf, F. A., Foster, E., Pellikka, P. A., Picard, M. H., Roman, M. J., Seward, J., Shanewise, J. S., et al. (2005) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2005.10.005 · Cited by 11,318
Self-citation
Prophylactic Implantation of a Defibrillator in Patients with Myocardial Infarction and Reduced Ejection Fraction
Moss, A. J., Zaręba, W., Hall, W. J., Klein, H., Wilber, D. J., Cannom, D. S., Daubert, J. P., Higgins, S. L., Brown, M. W., & Andrews, M. L. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa013474 · Cited by 6,885
Self-citation
Amiodarone or an Implantable Cardioverter–Defibrillator for Congestive Heart Failure
Bardy, G. H., Lee, K. L., Mark, D. B., Poole, J. E., Packer, D. L., Boineau, R., Domanski, M., Troutman, C., Anderson, J., Johnson, G., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043399 · Cited by 6,552
The Effect of Cardiac Resynchronization on Morbidity and Mortality in Heart Failure
Cleland, J. G. F., Daubert, J., Erdmann, E., Freemantle, N., Gras, D., KAPPENBERGER, L. J., & Tavazzi, L. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050496 · Cited by 6,300
Self-citation
Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure
Bristow, M. R., Saxon, L. A., Boehmer, J., Krueger, S., Kass, D. A., De Marco, T., Carson, P., DiCarlo, L., DeMets, D., White, B. G., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032423 · Cited by 5,812
Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmia
Moss, A. J., Hall, W. J., Cannom, D. S., Daubert, J. P., Higgins, S. L., Klein, H., Levine, J. H., Saksena, S., Waldo, A. L., Wilber, D., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199612263352601 · Cited by 4,165
Self-citation
Dual-Chamber Pacing or Ventricular Backup Pacing in Patients With an Implantable Defibrillator: The Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial
The DAVID Trial Investigators* (2002) · JAMA · doi:10.1001/jama.288.24.3115 · Cited by 2,056
ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities
Epstein, A. E., Dimarco, J., Ellenbogen, K. A., Estes, N. A. M., Freedman, R. A., Gettes, L. S., Gillinov, A. M., Gregoratos, G., Hammill, S. C., Hayes, D. L., et al. (2008) · Circulation · doi:10.1161/circualtionaha.108.189742 · Cited by 1,772
Self-citation
Randomized Trial of Cardiac Resynchronization in Mildly Symptomatic Heart Failure Patients and in Asymptomatic Patients With Left Ventricular Dysfunction and Previous Heart Failure Symptoms
Linde, C. M., Abraham, W. T., Gold, M. R., Sutton, M. S. J., Ghio, S., & Daubert, J. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.08.027 · Cited by 1,269
Self-citation

Flagged first, then by citations

Show all 17 references

Sorted by citations

Items 701–800 of 1,002

Prognostic Value of QRS Duration After Transcatheter Aortic Valve Implantation for Aortic Stenosis Using the CoreValve
Meguro, K., Lellouche, N., Yamamoto, M., Fougères, E., Monin, J., Lim, P., Mouillet, G., Dubois‐Randé, J., & Teíger, E. (2013) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2013.02.032 · Cited by 28
Comparative Effectiveness of Cardiac Resynchronization Therapy With an Implantable Cardioverter-Defibrillator Versus Defibrillator Therapy Alone
Masoudi, F. A., Mi, X., Curtis, L. H., Peterson, P. N., Curtis, J. P., Fonarow, G. C., Hammill, S. C., Heidenreich, P. A., Al‐Khatib, S. M., Piccini, J. P., et al. (2014) · Annals of Internal Medicine · doi:10.7326/m13-1879 · Cited by 28
Effect of Cardiac Resynchronization Therapy on Left Ventricular Remodeling in Patients With Cardiac Sarcoidosis
Patel, D. R., Trulock, K. M., Toro, S., Grimaldi, A. S., Gonzalez, M. H., Moennich, L. A., Gorodeski, E. Z., Joyce, E., Niebauer, M. J., Wilkoff, B. L., et al. (2018) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2018.09.044 · Cited by 28
Scar burden is an independent and incremental predictor of cardiac resynchronisation therapy response
Harb, S. C., Toro, S., Bullen, J. A., Obuchowski, N. A., Xu, B., Trulock, K. M., Varma, N., Rickard, J., Grimm, R. A., Griffin, B. P., et al. (2019) · Open Heart · doi:10.1136/openhrt-2019-001067 · Cited by 28
Cardiac resynchronization therapy-heart failure (CRT-HF) clinic: A novel model of care
Gorodeski, E. Z., Magnelli-Reyes, C., Moennich, L. A., Grimaldi, A. S., & Rickard, J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0222610 · Cited by 28
Prevalence and Incidence of Intra-Ventricular Conduction Delays and Outcomes in Patients with Heart Failure and Reduced Ejection Fraction: Insights from PARADIGM-HF and ATMOSPHERE
Kristensen, S. L., Castagno, D., Shen, L., Jhund, P. S., Docherty, K. F., Rørth, R., Abraham, W. T., Desai, A. S., Dickstein, K., Rouleau, J. L., et al. (2020) · European Journal of Heart Failure · doi:10.1002/ejhf.1972 · Cited by 29
Self-citation
QRS duration predicts death and hospitalization among patients with atrial fibrillation irrespective of heart failure: evidence from the AFFIRM study
Whitbeck, M. G., Charnigo, R. J., Shah, J. S., MORALES, G. X., Leung, S., Fornwalt, B. K., Bailey, A. L., Ziada, K. M., Sorrell, V. L., Zegarra, M. M., et al. (2013) · EP Europace · doi:10.1093/europace/eut335 · Cited by 28
DNA damage repair and transcription
Berardi, P., Russell, M., El‐Osta, A., & Riabowol, K. T. (2004) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4179-8 · Cited by 28
The dilemma, causes and approaches to avoid recurrent hospital readmissions for patients with chronic heart failure
Zaya, M., Phan, A., & Schwarz, E. R. (2011) · Heart Failure Reviews · doi:10.1007/s10741-011-9256-0 · Cited by 29
Current Challenges in the Management of Heart Failure
Michel Komajda, N. (2015) · Circulation Journal · doi:10.1253/circj.cj-15-0368 · Cited by 27
Echocardiography-guided left ventricular lead placement for cardiac resynchronization therapy in ischemic vs nonischemic cardiomyopathy patients
Daya, H. A., Alam, M. B., ADELSTEIN, E. C., SCHWARTZMAN, D. S., Jain, S. K., Marek, J. J., Gorcsan, J., & Saba, S. (2014) · Heart Rhythm · doi:10.1016/j.hrthm.2014.01.023 · Cited by 27
Brain Natriuretic Peptide and Cardiac Resynchronization Therapy in Patients With Mildly Symptomatic Heart Failure
brenyo, A. J., Barsheshet, A., Rao, M. C., Huang, D. T.-C., Zaręba, W., McNitt, S. A., Hall, W. J., Peterson, D. R., Solomon, S. D., Moss, A. J., et al. (2013) · Circulation Heart Failure · doi:10.1161/circheartfailure.112.000174 · Cited by 27
Self-citation
Predictors of Spontaneous Reverse Remodeling in Mild Heart Failure Patients With Left Ventricular Dysfunction
brenyo, A. J., Barsheshet, A., Kutyifa, V., Ruwald, A., Rao, M. C., Zaręba, W., Pouleur, A., Knappe, D., Solomon, S. D., McNitt, S. A., et al. (2014) · Circulation Heart Failure · doi:10.1161/circheartfailure.113.000929 · Cited by 27
Self-citation
Cardiac Resynchronization Therapy Device Implantation Using a New Sensor-Based Navigation System
Richter, S., Döring, M., Gaspar, T., John, S., Rolf, S., Sommer, P., Hindricks, G., & Piorkowski, C. (2013) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.113.000066 · Cited by 27
Profound differences in prognostic impact of left ventricular reverse remodeling after cardiac resynchronization therapy relate to heart failure etiology
Martens, P., Nijst, P., Verbrugge, F. H., Dupont, M., Tang, W. H. W., & Müllens, W. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.08.021 · Cited by 28
Gender differences in electro-mechanical characteristics of left bundle branch block: Potential implications for selection and response of cardiac resynchronization therapy
Pooter, J. D., Kamoen, V., Haddad, M. E., Stroobandt, R., Buyzere, M. D., Jordaens, L. J. L. M., & Timmermans, F. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2017.10.055 · Cited by 26
Sex Differences in the Risk of First and Recurrent Ventricular Tachyarrhythmias Among Patients Receiving an Implantable Cardioverter-Defibrillator for Primary Prevention
Saxena, S., Goldenberg, I., McNitt, S. A., Hsich, E., Kutyifa, V., Bragazzi, N. L., Polonsky, B., Aktaş, M. K., Huang, D. T.-C., Rosero, S. Z., et al. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.17153 · Cited by 27
Self-citation
Baseline clinical characteristics of heart failure patients with reduced ejection fraction enrolled in the BUDAPEST‐CRT Upgrade trial
Merkely, B. P., Gellér, L., Zima, E., Osztheimer, I., Molnár, L., Földesi, C., Duray, G. Z., Wranicz, J. K., Németh, M., Gościńska-Bis, K., et al. (2022) · European Journal of Heart Failure · doi:10.1002/ejhf.2609 · Cited by 27
Efficacy of the antibacterial envelope to prevent cardiac implantable electronic device infection in a high-risk population
Chaudhry, U. A., Borgquist, R., Smith, J. G., & Mörtsell, D. (2022) · EP Europace · doi:10.1093/europace/euac119 · Cited by 26
Cardiac Resynchronization Therapy in Adult Patients with Repaired Tetralogy of Fallot and Left Ventricular Systolic Dysfunction
Merchant, F. M., Kella, D., Book, W., Langberg, J. J., & Lloyd, M. S. (2013) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.12284 · Cited by 27
Atrioventricular delay programming and the benefit of cardiac resynchronization therapy in MADIT-CRT
brenyo, A. J., Kutyifa, V., Moss, A. J., Mathias, A., Barsheshet, A., Pouleur, A., Knappe, D., McNitt, S. A., Polonsky, B., Huang, D. T.-C., et al. (2013) · Heart Rhythm · doi:10.1016/j.hrthm.2013.04.013 · Cited by 27
Self-citation
Cardiac resynchronization therapy: the issue of non-response
Padeletti, L., Perini, A. P., & Gronda, E. (2011) · Heart Failure Reviews · doi:10.1007/s10741-011-9250-6 · Cited by 27
Revisiting diastolic filling time as mechanistic insight for response to cardiac resynchronization therapy
Verbrugge, F. H., Verhaert, D., Grieten, L., Dupont, M., Rivero‐Ayerza, M., Vusser, P. D., Herendael, H. V., Reyskens, R., Vandervoort, P. M., Tang, W. H. W., et al. (2013) · EP Europace · doi:10.1093/europace/eut130 · Cited by 27
Cardiac MRI scar patterns differ by sex in an implantable cardioverter-defibrillator and cardiac resynchronization therapy cohort
Loring, Z., Strauss, D. G., Gerstenblith, G., Tomaselli, G. F., Weiss, R. G., & Wu, K. C. (2013) · Heart Rhythm · doi:10.1016/j.hrthm.2013.01.003 · Cited by 27
Cardiac Resynchronization by Cardiosphere-Derived Stem Cell Transplantation in an Experimental Model of Myocardial Infarction
Bonios, M. J., Chang, C. Y., Pinheiro, A. C., Dimaano, V. L. J., Higuchi, T., Melexopoulou, C., Bengel, F. M., Terrovitis, J. V., Abraham, T. P., & Abraham, M. R. (2011) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2011.03.003 · Cited by 27
Prognostic value of left ventricular reverse remodeling and performance improvement after cardiac resynchronization therapy: A prospective study
Menet, A., Guyomar, Y., Ennezat, P., Graux, P., Castel, A., Delelis, F., Heuls, S., Cuvelier, E., Gevaert, C., Goffic, C. L., et al. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.11.091 · Cited by 27
Comparative Effectiveness of CRT-D Versus Defibrillator Alone in HF Patients With Moderate-to-Severe Chronic Kidney Disease
Friedman, D. J., Singh, J. P., Curtis, J. P., Tang, W. H. W., Bao, H., Spatz, E. S., Hernandez, A. F., Patel, U. D., & Al‐Khatib, S. M. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.09.097 · Cited by 27
Cardiac Resynchronization in Women
de Waard, D., Manlucu, J., Gillis, A. M., Sapp, J. L., Bernick, J., Doucette, S. P., Tang, A., Wells, G. A., & Parkash, R. (2019) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2019.06.007 · Cited by 27
Performance of a novel active fixation quadripolar left ventricular lead for cardiac resynchronization therapy: Attain Stability Quad Clinical Study results
JACKSON, K. P., Færestrand, S., Philippon, F., Yee, R. K., Kong, M. H., Kloppe, A., Bongiorni, M. G., Lee, S. F., Canby, R. C., Pouliot, E., et al. (2020) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.14439 · Cited by 27
JCS / JHRS 2024 Guideline Focused Update on Management of Cardiac Arrhythmias
Iwasaki, Y., Noda, T., Akao, M., Fujino, T., Hirano, T., Inoue, K., Kusano, K., Nagai, T., Satomi, K., Shinohara, T., et al. (2025) · Journal of Arrhythmia · doi:10.1002/joa3.70033 · Cited by 28
Acute and Chronic Response to CRT in Narrow QRS Patients
on behalf of the ESTEEM-CRT Investigators, Donahue, T., Niazi, I. K., León, A. R., Stucky, M. J., & Herrmann, K. L. (2011) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-011-9338-3 · Cited by 25
When to Stop a Clinical Trial Early for Benefit: Lessons Learned and Future Approaches
Zannad, F. M., Stough, W. G., McMurray, J. J. V., Remme, W. J., Pitt, B., BORER, J. S., Geller, N. L., & Pocock, S. (2012) · Circulation Heart Failure · doi:10.1161/circheartfailure.111.965707 · Cited by 26
Role of echocardiography before cardiac resynchronization therapy: new advances and current developments
Maréchaux, S., Menet, A., Guyomar, Y., Ennezat, P. V., Guerbaaï, R.-A., Graux, P., & Tribouilloy, C. M. (2016) · Echocardiography · doi:10.1111/echo.13334 · Cited by 26
Novel bradycardia pacing strategies
Heckman, L. I. B., Vijayaraman, P., LUERMANS, J. G. L. M., van Stipdonk, A. M. W., Salden, F., Maass, A. H., Prinzen, F. W., & Vernooy, K. (2020) · Heart · doi:10.1136/heartjnl-2020-316849 · Cited by 26
Management of Heart Failure With Reduced Ejection Fraction
Rashid, A. M., Khan, M. S., Fudim, M., DeWald, T. A., DeVore, A. D., & Butler, J. (2023) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2023.101596 · Cited by 31
Impact of Using a Telescoping‐Support Catheter System for Left Ventricular Lead Placement on Implant Success and Procedure Time of Cardiac Resynchronization Therapy
JACKSON, K. P., Hegland, D. D., Frazier‐Mills, C. G., Piccini, J. P., Koontz, J. I., Atwater, B. D., Daubert, J. P., & WORLEY, S. J. (2013) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.12103 · Cited by 25
Self-citation
The determinants of clinical outcome and clinical response to CRT are not the same
Cleland, J. G. F., & Ghio, S. (2011) · Heart Failure Reviews · doi:10.1007/s10741-011-9268-9 · Cited by 26
Small left atrium and mild mitral regurgitation predict super-response to cardiac resynchronization therapy
Stefan, L., Sedláček, K., Cerna, D., Kryze, L., Vančura, V., Marek, T., & Kautzner, J. (2012) · EP Europace · doi:10.1093/europace/eus075 · Cited by 26
Implantable Cardioverter–Defibrillator Use in Older Adults
Kramer, D. B., Matlock, D. D., Buxton, A. E., Goldstein, N. E., Goodwin, C., Green, A. R., Kirkpatrick, J. N., Knoepke, C. E., Lampert, R. J., Mueller, P. S., et al. (2015) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.114.001660 · Cited by 26
Clinical Outcomes According to QRS Duration and Morphology in the Eplerenone in Mild Patients: Hospitalization and SurvIval Study in Heart Failure (EMPHASIS-HF)
Cannon, J. A., Collier, T. J., Shen, L., Swedberg, K. B., Krum, H., van Veldhuisen, D. J., Vincent, J., Pocock, S., Pitt, B., Zannad, F. M., et al. (2015) · European Journal of Heart Failure · doi:10.1002/ejhf.303 · Cited by 26
Current Pacemaker and Defibrillator Therapy
Trappe, H., & Gummert, J. F. (2011) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2011.0372 · Cited by 26
Active fixation of a thin transvenous left-ventricular lead by a side helix facilitates targeted and stable placement in cardiac resynchronization therapy
Keilegavlen, H., Hovstad, T., & Færestrand, S. (2015) · EP Europace · doi:10.1093/europace/euv272 · Cited by 26
Applicability of a risk score for prediction of the long-term benefit of the implantable cardioverter defibrillator in patients receiving cardiac resynchronization therapy
Barra, S., Looi, K., Gajendragadkar, P. R., Khan, F. Z., Virdee, M., & Agarwal, S. (2015) · EP Europace · doi:10.1093/europace/euv352 · Cited by 26
Ventricular pacing – Electromechanical consequences and valvular function
Ebrille, E., DeSimone, C. V., Vaidya, V. R., Chahal, C. A. A., Nkomo, V. T., & Asirvatham, S. J. (2016) · Indian Pacing and Electrophysiology Journal · doi:10.1016/j.ipej.2016.02.013 · Cited by 27
Impact of QRS Complex Duration and Morphology on Left Ventricular Reverse Remodelling and Left Ventricular Function Improvement After Cardiac Resynchronization Therapy
van der Bijl, P., Khidir, M., Leung, M., Mertens, B. J. A., Marsan, N. A., Delgado, V., & Bax, J. J. (2017) · European Journal of Heart Failure · doi:10.1002/ejhf.769 · Cited by 26
Heart Failure and Sudden Cardiac Death
Saour, B., Smith, B., & Yancy, C. W. (2017) · Cardiac Electrophysiology Clinics · doi:10.1016/j.ccep.2017.07.010 · Cited by 27
Rate-Response Programming Tailored to the Force-Frequency Relationship Improves Exercise Tolerance in Chronic Heart Failure
Gierula, J., Paton, M. F., Lowry, J. E., Jamil, H. A., Byrom, R. J., Drozd, M., Garnham, J. O., Cubbon, R. M., Cairns, D. A., Kearney, M. T., et al. (2017) · JACC Heart Failure · doi:10.1016/j.jchf.2017.09.018 · Cited by 28
Safety and Feasibility of Cephalic Venous Access for Cardiac Resynchronization Device Implantation
Ussen, B., Dhillon, P. S., Anderson, L., Beeton, I., Hickman, M., & Gallagher, M. M. (2010) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2010.02975.x · Cited by 26
Performance of the Seattle Heart Failure Model in Implantable Defibrillator Patients Treated With Cardiac Resynchronization Therapy
Smith, T., Levy, W. C., Schaer, B. A., BALK, A., Sticherling, C., Jordaens, L. J. L. M., & Theuns, D. A. M. J. (2012) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2012.03.038 · Cited by 26
The Importance of Worsening Heart Failure in Ambulatory Patients
Mallick, A., Gandhi, P. U., Gaggin, H. K., Ibrahim, N., & Januzzi, J. L. (2016) · JACC: Heart Failure · doi:10.1016/j.jchf.2016.03.012 · Cited by 25
Left Bundle Branch Block-associated Cardiomyopathy: A New Approach
Ponnusamy, S. S., Vijayaraman, P., & Ellenbogen, K. A. (2024) · Arrhythmia & Electrophysiology Review · doi:10.15420/aer.2024.14 · Cited by 25
Arritmias ventriculares en superrespondedores a la terapia de resincronización cardiaca
García‐Lunar, I., Castro‐Urda, V., Toquero‐Ramos, J., Mingo‐Santos, S., Moñivas‐Palomero, V., Mitroi, C. D., Sánchez-García, M., Pérez-Pereira, E., Delgado, H. E., & Lozano, I. F. (2014) · Revista Española de Cardiología · doi:10.1016/j.recesp.2014.01.017 · Cited by 25
Absolute survival after cardiac resynchronization therapy according to baseline QRS duration: A multinational 10-year experience
Gasparini, M., Leclercq, C., Yu, C., Auricchio, A., Steinberg, J. S., Lamp, B., Klersy, C., & Leyva, F. (2013) · American Heart Journal · doi:10.1016/j.ahj.2013.10.017 · Cited by 25
Active fixation mechanism complicates coronary sinus lead extraction and limits subsequent reimplantation targets
Cronin, E. M., Ingelmo, C. P., Rickard, J., Wazni, O. M., Martin, D. O., Wilkoff, B. L., & Baranowski, B. J. (2012) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-012-9704-3 · Cited by 25
Maximal Electric Separation–Guided Placement of Right Ventricular Lead Improves Responders in Cardiac Resynchronization Defibrillator Therapy
Miranda, R. I., Nault, M. A., Johri, A. M., Simpson, C. S., Michael, K. A., Abdollah, H., Baranchuk, A. M., & Redfearn, D. (2012) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.111.967208 · Cited by 25
Battery longevity from cardiac resynchronization therapy defibrillators: differences between manufacturers and discrepancies with published product performance reports
Alam, M. B., Munir, M. B., Rattan, R., ADELSTEIN, E. C., Jain, S. K., & Saba, S. (2016) · EP Europace · doi:10.1093/europace/euw044 · Cited by 25
Effects of Mechanical Dyssynchrony on Coronary Flow: Insights From a Computational Model of Coupled Coronary Perfusion With Systemic Circulation
Fan, L., Namani, R., Choy, J. S., Kassab, G. S., & Lee, L. C. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00915 · Cited by 25
Cardiac resynchronization therapy: Current status and near-future prospects
Nakai, T., Ikeya, Y., Kogawa, R., & Okumura, Y. (2021) · Journal of Cardiology · doi:10.1016/j.jjcc.2021.10.021 · Cited by 25
Guía ESC 2021 sobre estimulación cardiaca y terapia de resincronización
Glikson, M., Nielsen, J. C., Kronborg, M. B., Michowitz, Y., Auricchio, A., Barbash, I. M., Barrabés, J. A., Boriani, G., Braunschweig, F., Brignole, M., et al. (2022) · Revista Española de Cardiología · doi:10.1016/j.recesp.2021.10.025 · Cited by 28
Diretriz Brasileira de Dispositivos Cardíacos Eletrônicos Implantáveis – 2023
Teixeira, R. A., Fagundes, A. A., Baggio, J. M., de Oliveira, J. C., Medeiros, P. D. T. J., Valdigem, B. P., Teno, L. A. C., Silva, R. T., de Melo, C. S., Elías, J., et al. (2023) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20220892 · Cited by 53
Outcomes of Upgrading to LBBP in CRT Nonresponders
Chen, X., Jin, Q., Qiu, Z., Qian, C., Liang, Y., Wang, J., Qin, S., Bai, J., Wang, W., Chen, H., et al. (2023) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2023.08.031 · Cited by 25
Rates of Upgrade of ICD Recipients to CRT in Clinical Practice and the Potential Impact of the More Liberal Use of CRT at Initial Implant
Scott, P. A., WHITTAKER, A., Zeb, M., WATTS, E., YUE, A. M., Roberts, P. R., & Morgan, J. M. (2011) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2011.03255.x · Cited by 25
Inefficacy Interim Monitoring Procedures in Randomized Clinical Trials: The Need to Report
Korn, E. L., & Freidlin, B. (2011) · The American Journal of Bioethics · doi:10.1080/15265161.2010.546471 · Cited by 25
Local electrogram delay recorded from left ventricular lead at implant predicts response to cardiac resynchronization therapy: Retrospective study with 1 year follow up
Polášek, R., Kucera, P., Nedbal, P., Roubíček, T., Belza, T., Hanuliaková, J., Horak, D., Wichterle, D., & Kautzner, J. (2012) · BMC Cardiovascular Disorders · doi:10.1186/1471-2261-12-34 · Cited by 25
Effects of Cardiac Resynchronization Therapy on Muscle Sympathetic Nerve Activity
Kuniyoshi, R. R., Filho, M. M., Negrão, C. E., de Siqueira, S. F., Rondon, M. U. P. B., Trombetta, I. C., Kuniyoshi, F. H. S., Laterza, M. C., Nishioka, S., Costa, R., et al. (2013) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.12254 · Cited by 25
Cardiac resynchronization therapy in the ageing population – With or without an implantable defibrillator?
Döring, M., Ebert, M., Dagres, N., Müssigbrodt, A., Bode, K., Knopp, H., Kühl, M., Hindricks, G., & Richter, S. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2018.03.087 · Cited by 24
Cardiac resynchronization therapy guided by cardiac magnetic resonance imaging: A prospective, single-centre randomized study (CMR-CRT)
Kočková, R., Sedláček, K., Wichterle, D., Šikula, V., Tintěra, J., Jansová, H., Pravečková, A., Langová, R., Krýže, L., El-Husseini, W., et al. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2018.06.009 · Cited by 24
Clinical Effectiveness of Cardiac Resynchronization Therapy Versus Medical Therapy Alone Among Patients With Heart Failure
Khazanie, P., Hammill, B. G., Qualls, L. G., Fonarow, G. C., Hammill, S. C., Heidenreich, P. A., Al‐Khatib, S. M., Piccini, J. P., Masoudi, F. A., Peterson, P. N., et al. (2014) · Circulation Heart Failure · doi:10.1161/circheartfailure.113.000838 · Cited by 25
Saudi Heart Association (SHA) guidelines for the management of heart failure
AlHabeeb, W., Alayoubi, F., Alghalayini, K. W., Ghofaili, F. A., Hebaishi, Y. A., Al‐Jazairi, A. S., Al-Mallah, M. H., Almasood, A. S., Qaseer, M. A., AlSaif, S. M., et al. (2019) · Journal of the Saudi Heart Association · doi:10.1016/j.jsha.2019.06.004 · Cited by 26
Complications of left bundle branch area pacing compared with biventricular pacing in candidates for resynchronization therapy: Results of a propensity score–matched analysis from a multicenter registry
Palmisano, P., Dell’Era, G., Guerra, F., Ammendola, E., Ziacchi, M., Laffi, M., Donateo, P., Guido, A., Ghiglieno, C., Parlavecchio, A., et al. (2024) · Heart Rhythm · doi:10.1016/j.hrthm.2024.02.053 · Cited by 24
Left bundle branch area pacing compared with biventricular pacing for cardiac resynchronization therapy in patients with left ventricular ejection fraction ≤50%: Results from the International Collaborative LBBAP Study (I-CLAS)
Morcos, R., Vijayaraman, P., Cano, Ó., Zanon, F., Ponnusamy, S. S., Herweg, B., Sharma, P. S., Jastrzębski, M., Molina‐Lerma, M., Whinnett, Z. I., et al. (2025) · Heart Rhythm · doi:10.1016/j.hrthm.2025.04.005 · Cited by 24
Vector Selection of a Quadripolar Left Ventricular Pacing Lead Affects Acute Hemodynamic Response to Cardiac Resynchronization Therapy: A Randomized Cross-Over Trial
Asbach, S., Hartmann, M., Wengenmayer, T., Graf, E., Bode, C., & Biermann, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067235 · Cited by 24
Comparing outcome of patients with coronary artery disease and dilated cardiomyopathy in ICD and CRT recipients: data from the German DEVICE—registry
Wasmer, K., Köbe, J., Andresen, D., Zahn, R., Spitzer, S. G., Jehle, J., Brachmann, J., Stellbrink, C., Martens, E., Hochadel, M., et al. (2013) · Clinical Research in Cardiology · doi:10.1007/s00392-013-0559-0 · Cited by 24
Self-citation
Adding the implantable cardioverter-defibrillator to cardiac resynchronization therapy is associated with improved long-term survival in ischaemic, but not in non-ischaemic cardiomyopathy
Witt, C. T., Kronborg, M. B., Nohr, E. A., Mortensen, P. T., Gerdes, C., Jensen, H. K., & Nielsen, J. C. (2015) · EP Europace · doi:10.1093/europace/euv212 · Cited by 24
Geschlecht und Herz-Kreislauf-Erkrankungen
Regitz‐Zagrosek, V. (2017) · Der Internist · doi:10.1007/s00108-017-0214-3 · Cited by 24
Effect of Expanding Evidence and Evolving Clinical Guidelines on the Prevalence of Indication for Cardiac Resynchronization Therapy in Patients with Heart Failure
Lund, L. H., Svennblad, B., Dahlström, U., & Ståhlberg, M. (2017) · European Journal of Heart Failure · doi:10.1002/ejhf.929 · Cited by 24
Cardiac resynchronization therapy: How did consensus guidelines from Europe and the United States evolve in the last 15 years?
Boriani, G., Ziacchi, M., Nesti, M., Battista, A., Placentino, F., Malavasi, V. L., Diemberger, I., & Padeletti, L. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2018.01.039 · Cited by 24
Cardiac resynchronization therapy and ventricular tachyarrhythmia burden
Tankut, S. S., Goldenberg, I., Kutyifa, V., Zaręba, W., Bragazzi, N. L., McNitt, S. A., Huang, D. T.-C., Aktaş, M. K., & Younis, A. (2021) · Heart Rhythm · doi:10.1016/j.hrthm.2020.12.034 · Cited by 24
Optimal effectiveness of heart failure management — an umbrella review of meta-analyses examining the effectiveness of interventions to reduce (re)hospitalizations in heart failure
Hafkamp, F. J., Tio, R. A., Otterspoor, L., Greef, T. V.-D., van Steenbergen, G. J., van de Ven, A. R. T., Smits, G., Post, H., & van Veghel, D. (2022) · Heart Failure Reviews · doi:10.1007/s10741-021-10212-8 · Cited by 24
Efficacy of implantable haemodynamic monitoring in heart failure across ranges of ejection fraction: a systematic review and meta-analysis
Curtain, J. P., Lee, M. M. Y., McMurray, J. J. V., Gardner, R. S., Petrie, M. C., & Jhund, P. S. (2022) · Heart · doi:10.1136/heartjnl-2022-321885 · Cited by 24
Multicenter Study of Survival Benefit of Cardiac Resynchronization Therapy in Pediatric and Congenital Heart Disease
Chubb, H., Mah, D. Y., Shah, M. J., Lin, K. Y., Peng, D. M., Hale, B., May, L. J., Etheridge, S. P., Goodyer, W. R., Ceresnak, S. R., et al. (2024) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2023.11.008 · Cited by 24
Reduced Risk of Life-Threatening Ventricular Tachyarrhythmias with Cardiac Resynchronization Therapy: Relationship to Left Ventricular Ejection Fraction
Kutyifa, V., Moss, A. J., Solomon, S. D., McNitt, S. A., Aktaş, M. K., Barsheshet, A., Merkely, B. P., Zaręba, W., & Goldenberg, I. (2015) · European Journal of Heart Failure · doi:10.1002/ejhf.311 · Cited by 24
Self-citation
Longer right to left ventricular activation delay at cardiac resynchronization therapy implantation is associated with improved clinical outcome in left bundle branch block patients
Kosztin, A., Kutyifa, V., Nagy, V. K., Gellér, L., Zima, E., Molnár, L., Szilágyi, S., Özcan, E. E., Széplaki, G., & Merkely, B. P. (2015) · EP Europace · doi:10.1093/europace/euv117 · Cited by 24
Cellular Evidence of Reverse Cardiac Remodeling Induced by Cardiac Resynchronization Therapy
Orrego, C. M., Nasir, N., Oliveira, G. H., Flores‐Arredondo, J. H., Cordero‐Reyes, A. M., Loebe, M. M., Youker, K. A., & Torre‐Amione, G. (2011) · Congestive Heart Failure · doi:10.1111/j.1751-7133.2011.00227.x · Cited by 24
Survival of Patients With Biventricular Devices After Device Infection, Extraction, and Reimplantation
Rickard, J., Tarakji, K. G., Cheng, A., SPRAGG, D. D., Cantillon, D. J., Martin, D. O., Baranowski, B. J., Gordon, S. M., Tang, W. H. W., Kanj, M., et al. (2013) · JACC Heart Failure · doi:10.1016/j.jchf.2013.05.009 · Cited by 26
Left Ventricular Reverse Remodeling, Device-Related Adverse Events, and Long-Term Outcome After Cardiac Resynchronization Therapy in the Elderly
Höke, U., Putter, H., van der Velde, E. T., Schalij, M. J., Delgado, V., Bax, J. J., & Marsan, N. A. (2014) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.113.000821 · Cited by 24
Long term impact of cardiac contractility modulation on QRS duration
Röger, S., Michels-Zetsche, J. D., Heggemann, F., Stach, K., Rousso, B., Borggrefe, M., & Kuschyk, J. (2014) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2014.08.011 · Cited by 24
Cardiac resynchronization therapy: a cost or an investment?
Boriani, G., Mantovani, L. G., Biffi, M., Schalij, M. J., Martignani, C., Leclercq, C., Bax, J. J., & Auricchio, A. (2011) · EP Europace · doi:10.1093/europace/eur079 · Cited by 24
Improved success rate of cardiac resynchronization therapy implant by employing an active fixation coronary sinus lead
Lüdorff, G., Kranig, W., Grove, R., Wolff, E., Heimlich, G., & Thale, J. (2010) · EP Europace · doi:10.1093/europace/euq078 · Cited by 23
Real‐World Assessment of Acute Left Ventricular Lead Implant Success and Complication Rates: Results from the Attain Success Clinical Trial
Hummel, J. D., Coppess, M. A., Osborn, J. S., Yee, R. K., Fung, J. W., Augostini, R. S., Li, S., Hine, D. S., & Singh, J. P. (2016) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.12939 · Cited by 24
Effect of Interventricular Electrical Delay on Atrioventricular Optimization for Cardiac Resynchronization Therapy
Gold, M. R., Yu, Y., Singh, J. P., Birgersdotter-Green, U. M., Steín, K. M., Wold, N. D., Meyer, T. E., & Ellenbogen, K. A. (2018) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.117.006055 · Cited by 24
The Role of Sacubitril/Valsartan in the Management of Cardiac Resynchronization Therapy Non-Responders: A Retrospective Analysis
Chun, K., Oh, J., Yu, H. T., Lee, C. J., Kim, T., Uhm, J., Pak, H., Lee, M., Joung, B., & Kang, S. (2020) · ESC Heart Failure · doi:10.1002/ehf2.12988 · Cited by 24
Permanent His Bundle Pacing in Patients With Congenital Complete Heart Block
Dandamudi, G., Simon, J. W., Cano, Ó., Master, V. M., Koruth, J. S., Naperkowski, A. M., Kean, A. C., Schaller, R. D., Ellenbogen, K. A., Kron, J., et al. (2020) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2020.09.015 · Cited by 24
Actual conditions of implantable defibrillation therapy over 5 years in Japan
Shimizu, A., Nitta, T., Kurita, T., Imai, K., Kobayashi, Y., Soejima, K., Niwano, S., Watanabe, S., Abe, H., Aizawa, Y., et al. (2012) · Journal of Arrhythmia · doi:10.1016/j.joa.2012.03.014 · Cited by 24
Predictors and Risk of Ventricular Tachyarrhythmias or Death in Black and White Cardiac Patients
Sabbag, A., Goldenberg, I., Moss, A. J., McNitt, S. A., Glikson, M., Biton, Y., Jackson, L. R., Polonsky, B., Zaręba, W., & Kutyifa, V. (2016) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2016.03.003 · Cited by 23
Self-citation
Physiological pacing: mechanisms, clinical indications, and perspectives
Whinnett, Z. I., Naraen, A., Vijayaraman, P., Cleland, J. G. F., & Keene, D. (2025) · European Heart Journal · doi:10.1093/eurheartj/ehaf440 · Cited by 25
The Effect of Cardiac Resynchronization Therapy on Left Ventricular Diastolic Function Assessed with Speckle-Tracking Echocardiography
Shanks, M., Antoni, M. L., Höke, U., Bertini, M., Ng, A. C. T., Auger, D., Marsan, N. A., van Erven, L., Holman, E. R., Schalij, M. J., et al. (2011) · European Journal of Heart Failure · doi:10.1093/eurjhf/hfr115 · Cited by 23
Is mechanical dyssynchrony a therapeutic target in heart failure with preserved ejection fraction?
Menet, A., Greffe, L., Ennezat, P., Delelis, F., Guyomar, Y., Castel, A., Guiot, A., Graux, P., Tribouilloy, C. M., & Maréchaux, S. (2014) · American Heart Journal · doi:10.1016/j.ahj.2014.08.004 · Cited by 23
ECG parameters predict left ventricular conduction delay in patients with left ventricular dysfunction
Pastore, G., Maines, M., Marcantoni, L., Zanon, F., Noventa, F., CORBUCCI, G., Baracca, E., Aggio, S., Picariello, C., Lanza, D., et al. (2016) · Heart Rhythm · doi:10.1016/j.hrthm.2016.07.010 · Cited by 23
Cardiac Implantable Electronic Devices Following Heart Transplantation
DeFilippis, E. M., Rubin, G. A., FARR, M. A., BIVIANO, A. B., Wan, E. Y., Takeda, K., Garan, H., Topkara, V. K., & Yarmohammadi, H. (2020) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2020.06.023 · Cited by 23

Authors: Moss, A. J., Hall, W. J., Cannom, D. S., Klein, H., Brown, M. W., Daubert, J. P., Estes, N. A. M., Foster, E., Greenberg, H., Higgins, S. L., Pfeffer, M. A., Solomon, S. D., Wilber, D., & Zareba, W.
Affiliations: University of Rochester Medicine (US)
Good Samaritan Hospital (US)
Duke Medical Center (US)
University of California, San Francisco (US)
St. Luke's-Roosevelt Hospital Center (US)
Scripps Memorial Hospital (US)
Brigham and Women's Hospital (US)
Loyola University Medical Center (US)
ORCID: Moss, Arthur J.
Hall, W. Jackson
Cannom, David S.
Klein, Helmut
Daubert, James P.
Greenberg, Henry
Pfeffer, Marc A.
Solomon, Scott D.
Wilber, David
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2009-10
Volume: 361
Issue: 14
Pages: 1329-1338
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmoa0906431
OpenAlex: W2146521529
Cited by: 3,157
References: 17
Citations by year: 2026: 106 · 2025: 116 · 2024: 137 · 2023: 188 · 2022: 140 · 2021: 155 · 2020: 163 · 2019: 173 · 2018: 174 · 2017: 199 · 2016: 210 · 2015: 210 · 2014: 227 · 2013: 243 · 2012: 267
FWCI: 151.00
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Institutional Research Information System (Università degli Studi di Brescia) (submittedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Health Sciences › Medicine › Emergency Medicine › Cardiac Arrest and Resuscitation
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Keywords: cardiac resynchronization therapy, implantable cardioverter-defibrillator, heart failure prevention, reduced ejection fraction, wide QRS complex, ischemic cardiomyopathy, non-ischemic cardiomyopathy, left ventricular volume, ejection fraction, mortality, asymptomatic patients
MeSH terms: Aged, Cardiac Pacing, Artificial, Electric Countershock, Female, Heart Failure, Humans, Male, Middle Aged, Pacemaker, Artificial, Stroke Volume, Defibrillators, Implantable, Disease-Free Survival, Kaplan-Meier Estimate

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Cardiac-Resynchronization Therapy for the Prevention of Heart-Failure Events

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks