Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

Zannad, Faiez, McMurray, John J.V., Krum, Henry, van Veldhuisen, Dirk J., Swedberg, Karl, Shi, Harry, Vincent, John, Pocock, Stuart J., Pitt, Bertram·2011·New England Journal of Medicine

DOI 10.1056/nejmoa1009492

Cited by (1,004)

Items 401–500 of 1,004

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Merabet, Nassiba, Bellien, Jeremy, Glevarec, Etienne, Nicol, Lionel, Lucas, Daniele, Remy-Jouet, Isabelle, Bounoure, Frederic, Dreano, Yvonne, Wecker, Didier, Thuillez, Christian et al. · 2012 · Journal of Molecular and Cellular Cardiology
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Qingzhong Hu, Lina Yin, Rolf W. Hartmann · 2014 · Journal of Medicinal Chemistry
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Pharmacokinetics, safety and tolerability of the novel, selective mineralocorticoid receptor antagonist finerenone – results from first‐in‐man and relative bioavailability studies
Silvia Lentini, Roland Heinig, Nina Kimmeskamp‐Kirschbaum, Georg Wensing · 2015 · Fundamental and Clinical Pharmacology
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Tohru Masuyama, Takeshi Tsujino, Hideki Origasa, Kazuhiro Yamamoto, Takashi Akasaka, Yutaka Hirano, Nobuyuki Ohte, Takashi Daimon, Satoshi Nakatani, Hiroshi Ito · 2012 · Circulation Journal
Mineralocorticoid receptor antagonists for heart failure: systematic review and meta-analysis
Nicolas M. Berbenetz, Marko Mrkobrada · 2016 · BMC Cardiovascular Disorders
2020 ACC/AHA Clinical Performance and Quality Measures for Adults With Heart Failure
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Beta-blockers and inhibitors of the renin-angiotensin aldosterone system for chronic heart failure with preserved ejection fraction
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Jishnu Malgie, Pascal R.D. Clephas, Hans‐Peter Brunner‐La Rocca, Rudolf A. de Boer, Jasper Jan Brugts · 2023 · Heart Failure Reviews
Mineralocorticoid receptor overactivation: targeting systemic impact with non-steroidal mineralocorticoid receptor antagonists
Gianluigi Savarese, Felix Lindberg, Gerasimos S Filippatos, Javed Butler, Stefan D. Anker · 2023 · Diabetologia
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Subodh Verma, Avinash Pandey, Arjun K. Pandey, Javed Butler, John S. Lee, Hwee Teoh, C. David Mazer, Mikhail Kosiborod, Francesco Cosentino, Stefan D. Anker et al. · 2023 · American Journal of Physiology-Heart and Circulatory Physiology
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Mineralocorticoid receptor antagonists—pharmacodynamics and pharmacokinetic differences
Jun Yang, Morag J. Young · 2016 · Current Opinion in Pharmacology
The renin-angiotensin-aldosterone system in heart failure for the non-specialist: the past, the present and the future
Christopher Orsborne, Parminder S Chaggar, Steven M. Shaw, Simon G. Williams · 2016 · Postgraduate Medical Journal
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Chao Li, Xue‐Nan Sun, Mengru Zeng, Xiaojun Zheng, Yuyao Zhang, Qiangyou Wan, Wuchang Zhang, Chaoji Shi, Lin‐Juan Du, Tang-Jun Ai et al. · 2017 · Hypertension
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Timothy James Cole, Morag J. Young · 2017 · Journal of Endocrinology
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Yoshio Takemoto, Rafael J. Ramírez, Kuljeet Kaur, O. Salvador, Daniela Ponce‐Balbuena, Roberto Ramos‐Mondragón, Steven R. Ennis, Guadalupe Guerrero‐Serna, Omer Berenfeld, José Jalife · 2017 · Journal of the American College of Cardiology
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Mario Boehm, Nadine D. Arnold, Adam T. Braithwaite, Josephine A. Pickworth, Changwu Lu, Tatyana Novoyatleva, David Gerard Kiely, Friedrich Grimminger, Hossein Ardeschir Ghofrani, Norbert Weißmann et al. · 2018 · BMC Pulmonary Medicine
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