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Tai Chi and Postural Stability in Patients with Parkinson's Disease
Open accessAbstract
BACKGROUND: Patients with Parkinson's disease have substantially impaired balance, leading to diminished functional ability and an increased risk of falling. Although exercise is routinely encouraged by health care providers, few programs have been proven effective. METHODS: We conducted a randomized, controlled trial to determine whether a tailored tai chi program could improve postural control in patients with idiopathic Parkinson's disease. We randomly assigned 195 patients with stage 1 to 4 disease on the Hoehn and Yahr staging scale (which ranges from 1 to 5, with higher stages indicating more severe disease) to one of three groups: tai chi, resistance training, or stretching. The patients participated in 60-minute exercise sessions twice weekly for 24 weeks. The primary outcomes were changes from baseline in the limits-of-stability test (maximum excursion and directional control; range, 0 to 100%). Secondary outcomes included measures of gait and strength, scores on functional-reach and timed up-and-go tests, motor scores on the Unified Parkinson's Disease Rating Scale, and number of falls. RESULTS: The tai chi group performed consistently better than the resistance-training and stretching groups in maximum excursion (between-group difference in the change from baseline, 5.55 percentage points; 95% confidence interval [CI], 1.12 to 9.97; and 11.98 percentage points; 95% CI, 7.21 to 16.74, respectively) and in directional control (10.45 percentage points; 95% CI, 3.89 to 17.00; and 11.38 percentage points; 95% CI, 5.50 to 17.27, respectively). The tai chi group also performed better than the stretching group in all secondary outcomes and outperformed the resistance-training group in stride length and functional reach. Tai chi lowered the incidence of falls as compared with stretching but not as compared with resistance training. The effects of tai chi training were maintained at 3 months after the intervention. No serious adverse events were observed. CONCLUSIONS: Tai chi training appears to reduce balance impairments in patients with mild-to-moderate Parkinson's disease, with additional benefits of improved functional capacity and reduced falls. (Funded by the National Institute of Neurological Disorders and Stroke; ClinicalTrials.gov number, NCT00611481.).
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“Findings from these studies show that, following 24 weeks of twice weekly sessions, Tai Chi leads to improved stride length and maximum excursion as well as reduced falls compared to resistance training or stretching.”
From Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease (2013) · cites this paper as [17]
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“These benefits were retained for at least 2 months 17.”
From Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease (2013) · cites this paper as [17]
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Cites
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282
The Timed “Up & Go”: A Test of Basic Functional Mobility for Frail Elderly Persons
Podsiadlo, D., & Richardson, S. (1991) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1991.tb01616.x · Cited by 14,418
Parkinsonism: onset, progression, and mortality
Hoehn, M. M., & Yahr, M. D. (1967) · Neurology · doi:10.1212/wnl.17.5.427 · Cited by 12,107
The physical activity scale for the elderly (PASE): Development and evaluation
Washburn, R. A., Smith, K. W., Jette, A. M., & Janney, C. A. (1993) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(93)90053-4 · Cited by 3,256
Physical Activity and Public Health in Older Adults
Nelson, M. E., Rejeski, W. J., Blair, S. N., Duncan, P. W., Judge, J. O., King, A. C., Macera, C. A., & Castaneda‐Sceppa, C. (2007) · Circulation · doi:10.1161/circulationaha.107.185650 · Cited by 3,057
Functional Reach: A New Clinical Measure of Balance
Duncan, P. W., Weiner, D. K., Chandler, J., & Studenski, S. A. (1990) · Journal of Gerontology · doi:10.1093/geronj/45.6.m192 · Cited by 2,876
Diagnostic Criteria for Parkinson Disease
Gelb, D. J., Oliver, E., & Gilman, S. (1999) · Archives of Neurology · doi:10.1001/archneur.56.1.33 · Cited by 2,822
Members of the UPDRS Development Committee. Unified Parkinson's Disease Rating Scale
Fahn, S. (1987) · Medical Entomology and Zoology · Cited by 2,163
NELSON, M. E., REJESKI, W. J., BLAIR, S. N., DUNCAN, P. W., JUDGE, J. O., KING, A. C., MACERA, C. A., & CASTANEDA-SCEPPA, C. (2007) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3180616aa2 · Cited by 2,089
Wolf, S. L., Barnhart, H. X., Kutner, N. G., McNeely, E., Coogler, C., Xu, T., & Atlanta FICSIT Group (1996) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1996.tb01432.x · Cited by 1,142
Goodwin, V. A., Richards, S. H., Taylor, R. S., Taylor, A. H., & Campbell, J. L. (2008) · Movement Disorders · doi:10.1002/mds.21922 · Cited by 922
Tai Chi and Fall Reductions in Older Adults: A Randomized Controlled Trial
Li, F., Harmer, P., Fisher, K. J., McAuley, E., Chaumeton, N. R., Eckstrom, E., & Wilson, N. L. (2005) · The Journals of Gerontology Series A · doi:10.1093/gerona/60.2.187 · Cited by 750
Self-citationA meta‐analysis of six prospective studies of falling in Parkinson's disease
Pickering, R. M., Grimbergen, Y. A. M., Rigney, U., Ashburn, A., Mazibrada, G., Wood, B. H., Gray, P., Kerr, G., & Bloem, B. R. (2007) · Movement Disorders · doi:10.1002/mds.21598 · Cited by 587
Hirsch, M. A., Toole, T., Maitland, C., & Rider, R. A. (2003) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/s0003-9993(03)00046-7 · Cited by 464
Effects of a Group Exercise Program on Strength, Mobility, and Falls Among Fall-Prone Elderly Men
Rubenstein, L. Z., Josephson, K. R., Trueblood, P. R., Loy, S. F., Harker, J. O., Pietruszka, F. M., & Robbins, A. S. (2000) · The Journals of Gerontology Series A · doi:10.1093/gerona/55.6.m317 · Cited by 394
Li, F., Fisher, K. J., Harmer, P., Irbe, D., Tearse, R. G., & Weimer, C. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52255.x · Cited by 370
Self-citationAshburn, A. (2001) · Age and Ageing · doi:10.1093/ageing/30.1.47 · Cited by 330
Tai Chi improves balance and mobility in people with Parkinson disease
Hackney, M. E., & Earhart, G. M. (2008) · Gait & Posture · doi:10.1016/j.gaitpost.2008.02.005 · Cited by 295
Voukelatos, A., Cumming, R. G., Lord, S. R., & Rissel, C. E. (2007) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2007.01244.x · Cited by 280
Principles and Practice of Movement Disorders
(2011) · Elsevier eBooks · doi:10.1016/c2009-0-44357-5 · Cited by 276
Dibble, L. E., Addison, O. R., & Papa, E. V. (2009) · Neurology Report · doi:10.1097/npt.0b013e3181990fcc · Cited by 242
Quality improvement in neurology: AAN epilepsy quality measures
Fountain, N. B., Ness, P. C. V., Swain‐Eng, R. J., Tonn, S. T., & Bever, C. T. (2010) · Neurology · doi:10.1212/wnl.0b013e318203e9d1 · Cited by 230
Resistance Training and Gait Function in Patients with Parkinson’s Disease
Scandalis, T. A., Bosak, A. M., Berliner, J. C., Helman, L. L., & Wells, M. R. (2001) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/00002060-200101000-00011 · Cited by 222
Functional reach: J.A new clinical measure of balance
Duncan, P. (1990) · The Journals of Gerontology Series A · Cited by 183
Teaching tape for the motor section of the unified Parkinson's disease rating scale
Goetz, C. G., Stebbins, G. T., Chmura, T. A., Fahn, S., Klawans, H. L., & MARSDEN, C. D. (1995) · Movement Disorders · doi:10.1002/mds.870100305 · Cited by 154
Weighted Vest Exercise Improves Indices of Fall Risk in Older Women
Shaw, J. M., & Snow, C. M. (1998) · The Journals of Gerontology Series A · doi:10.1093/gerona/53a.1.m53 · Cited by 142
Translation of an Effective Tai Chi Intervention Into a Community-Based Falls-Prevention Program
Li, F., Harmer, P., Glasgow, R. E., Mack, K. A., Sleet, D. A., Fisher, K. J., Kohn, M. A., Millet, L. M., Mead, J., Xu, J., et al. (2008) · American Journal of Public Health · doi:10.2105/ajph.2007.120402 · Cited by 129
Self-citationQuality improvement in neurology: AAN Parkinson disease quality measures
Cheng, E. M., Tonn, S. T., Swain‐Eng, R. J., Factor, S. A., Weiner, W. J., & Bever, C. T. (2010) · Neurology · doi:10.1212/wnl.0b013e3181ff96dd · Cited by 109
Physiotherapy for Parkinson's disease: a comparison of techniques
Deane, K. H., Jones, D. E., Ellis‐Hill, C., Clarke, C. E., Playford, E. D., & Ben‐Shlomo, Y. (2001) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002815 · Cited by 102
Tai Chi–Based Exercise for Older Adults with Parkinson’s Disease: A Pilot-Program Evaluation
Li, F., Harmer, P., Fisher, K. J., Xu, J., Fitzgerald, K., & Vongjaturapat, N. (2007) · Journal of Aging and Physical Activity · doi:10.1123/japa.15.2.139 · Cited by 72
Self-citationGreendale, G. A., Salem, G. J., Young, J. T., Damesyn, M. A., Marion, M., Wang, M., & Reuben, D. B. (2000) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2000.tb02651.x · Cited by 65
Dibble, L. E., Hale, T. F., Marcus, R. L., Gerber, J. P., & LaStayo, P. C. (2006) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2006.05.016 · Cited by 55
Psychogenic Movement Disorders
Fahn, S., Jankovic, J. J., Hallett, M., & Jenner, P. G. (2007) · Elsevier eBooks · doi:10.1016/b978-0-443-07941-2.50029-2 · Cited by 45
Developing the Medication Change Questionnaire
Paterson, C., Symons, L., Britten, N., & Bargh, J. (2004) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1111/j.1365-2710.2004.00570.x · Cited by 13
The Role of Levodopa and Catechol-O-Methyltransferase Inhibitors
Nirenberg, M. J. (2005) · Elsevier eBooks · doi:10.1016/b978-0-7506-5428-9.50005-6 · Cited by 13
Physical therapy in Parkinson's disease
MacKay-Lyons, M. J., Turnbull, G., Comella, C. L., Stebbins, G. T., Brown-Toms, N., & Goetz, C. G. (1995) · Neurology · doi:10.1212/wnl.45.1.205 · Cited by 11
The Medical Management of Parkinson's Disease
Schapira, A. H. V. (2005) · Elsevier eBooks · doi:10.1016/b978-0-7506-5428-9.50010-x · Cited by 8
Physical therapy in Parkinson's disease
Graciès, J., Tse, W., Lugassy, M. M., & FRANK, J. (2007) · Handbook of clinical neurology · doi:10.1016/s0072-9752(07)84030-9 · Cited by 5
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- Deane KH, 2001, Cochrane Database Syst Rev, 1, CD002815
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Fox, S. H., Katzenschlager, R., Lim, S., Barton, B. R., de Bie, R. M. A., Seppi, K., Coelho, M. M., & Sampaio, C. (2018) · Movement Disorders · doi:10.1002/mds.27372 · Cited by 1,009
Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease
Petzinger, G. M., Fisher, B. E., McEwen, S., Beeler, J. A., Walsh, J. P., & Jakowec, M. W. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70123-6 · Cited by 798
Su, D., Cui, Y., He, C., Yin, P., Bai, R., Zhu, J., Lam, J. S. T., Zhang, J., Yan, R., Zheng, X., et al. (2025) · BMJ · doi:10.1136/bmj-2024-080952 · Cited by 751
Long-term effects of exercise and physical therapy in people with Parkinson disease
Mak, K. Y., Wong-Yu, I. S. K., Shen, X., & Chung, C. L. H. (2017) · Nature Reviews Neurology · doi:10.1038/nrneurol.2017.128 · Cited by 553
Schenkman, M., Moore, C. G., Kohrt, W. M., Hall, D. A., Delitto, A., Comella, C. L., Josbeno, D. A., Christiansen, C. L., Berman, B. D., Kluger, B. M., et al. (2018) · JAMA Neurology · doi:10.1001/jamaneurol.2017.3517 · Cited by 515
Metadata
- Authors
- Li, F., Harmer, P., Fitzgerald, K., Eckstrom, E., Stock, R., Galver, J., Maddalozzo, G., & Batya, S. S.
- Affiliations
- Oregon Research Institute (US)
- Willamette University (US)
- Oregon Health & Science University (US)
- Oregon State University (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2012-02-09
- Volume
- 366
- Issue
- 6
- Pages
- 511-519
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC3285459
- OpenAlex
- W2150072209
- Cited by
- 890
- References
- 39
- Citations by year
- 2026: 42 · 2025: 54 · 2024: 47 · 2023: 53 · 2022: 63 · 2021: 69 · 2020: 52 · 2019: 67 · 2018: 50 · 2017: 58 · 2016: 62 · 2015: 75 · 2014: 79 · 2013: 81 · 2012: 37
- FWCI
- 216.62
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (NS047130, R01NS047130)
- Topics
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
- Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
- Social Sciences › Arts and Humanities › Visual Arts and Performing Arts › Diversity and Impact of Dance
- Keywords
- Tai Chi, Parkinson's disease, postural stability, balance disorders, falls, exercise intervention, resistance training, stretching, limits of stability test, gait, functional reach test, fall prevention
- MeSH terms
- Aged, Postural Balance, Female, Gait, Humans, Male, Parkinson Disease, Outcome Assessment, Health Care, Tai Ji, Muscle Stretching Exercises, Resistance Training
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