The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“At 12 weeks, the primary endpoint (an absence of fever and at least 30% improvement on the ACR core set for JIA) was achieved in significantly more patients in the tocilizumab group than in the placebo group (85% versus 24%, p < 0.001) (De Benedetti et al., 2012”
From Targeting Interleukin-6 Signaling in Clinic (2019) · cites this paper as De Benedetti et al., 2012
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Measurement of health status in children with juvenile rheumatoid arthritis
Singh, G., Athreya, B. H., Fries, J. F., & Goldsmith, D. P. (1994) · Arthritis & Rheumatism · doi:10.1002/art.1780371209 · Cited by 838
De Benedetti, F., Alonzi, T., Moretta, A., Lazzaro, D., Costa, P., Poli, V, Martini, A., Ciliberto, G., & Fattori, E. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119207 · Cited by 529
Self-citationCazzola, M., Ponchio, L., de Benedetti, F., Ravelli, A., Rosti, V, Beguin, Y., Invernizzi, R., Barosi, G., & Martini, A. (1996) · Blood · doi:10.1182/blood.v87.11.4824.bloodjournal87114824 · Cited by 197
Self-citation
Research works printed but not linked: 25
- Petty RE, 2004, J Rheumatol, 31, 390
- Lomater C, 2000, J Rheumatol, 27, 491
- 10.1016/S0140-6736(07)60363-8 · DOI
- 10.1002/1529-0131(200008)43:8<1849::AID-ANR22>3.0.CO;2-F · DOI
- 10.1136/ard.2007.087593 · DOI
- 10.1136/ard.2007.087411 · DOI
- 10.1002/art.23437 · DOI
- 10.1136/ard.2007.076034 · DOI
- 10.1136/ard.2010.134254 · DOI
- De Benedetti F, 1998, J Rheumatol, 25, 203
- 10.1002/art.1780340912 · DOI · Paper page
- De Benedetti F, 1997, J Rheumatol, 24, 1403
- 10.1002/art.22175 · DOI · Paper page
- 10.1016/S0140-6736(08)60454-7 · DOI · Paper page
- 10.1136/adc.2010.188946 · DOI
- Brunner HI, 2002, J Rheumatol, 29, 1058
- 10.1056/NEJM200003163421103 · DOI
- 10.1002/1529-0131(199707)40:7<1202::AID-ART3>3.0.CO;2-R · DOI
- Ruperto N, 2001, Clin Exp Rheumatol, 19, S1
- Wallace CA, 2004, J Rheumatol, 31, 2290
- 10.1002/art.33496 · DOI
- 10.1002/art.1780341216 · DOI
- 10.1002/1529-0131(200011)43:11<2402::AID-ANR5>3.0.CO;2-C · DOI
- 10.1186/1546-0096-9-S1-O18 · DOI
- Hashkes PJ, 2010, Arthritis Rheum, 62, 599, 10.1002/art.27218 · DOI
Cited by
Sorted by citations
McGonagle, D., Sharif, K., O'Regan, A., & Bridgewood, C. (2020) · Autoimmunity Reviews · doi:10.1016/j.autrev.2020.102537 · Cited by 1,654
Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer
Jones, S. A., & Jenkins, B. J. (2018) · Nature Reviews Immunology · doi:10.1038/s41577-018-0066-7 · Cited by 1,102
Targeting Interleukin-6 Signaling in Clinic
Kang, S., Tanaka, T., Narazaki, M., & Kishimoto, T. (2019) · Immunity · doi:10.1016/j.immuni.2019.03.026 · Cited by 904
How COVID-19 induces cytokine storm with high mortality
Hojyo, S., Uchida, M., Tanaka, K., Hasebe, R., Tanaka, Y., Murakami, M., & Hirano, T. (2020) · Inflammation and Regeneration · doi:10.1186/s41232-020-00146-3 · Cited by 663
The Immunology of Macrophage Activation Syndrome
Crayne, C. B., Albeituni, S., Nichols, K. E., & Cron, R. Q. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00119 · Cited by 633
The role of interleukin-6 signaling in nervous tissue
Rothaug, M., Becker-Pauly, C., & Rose-John, S. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2016.03.018 · Cited by 491
Metadata
- Authors
- De Benedetti, F., Brunner, H. I., Ruperto, N., Kenwright, A., Wright, S., Calvo, I., Cuttica, R., Ravelli, A., Schneider, R., Woo, P., Wouters, C., Xavier, R., Zemel, L., Baildam, E., Burgos-Vargas, R., Dolezalova, P., Garay, S. M., Merino, R., Joos, R., Grom, A., Wulffraat, N., Zuber, Z., Zulian, F., Lovell, D., & Martini, A.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2012-12-20
- Volume
- 367
- Issue
- 25
- Pages
- 2385-2395
- ISSN
- 0028-4793
- 1533-4406
- Cited by
- 763
- References
- 3
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
