Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
Brahmer, Julie R., Tykodi, Scott S., Chow, Laura Q.M., Hwu, Wen-Jen, Topalian, Suzanne L., Hwu, Patrick, Drake, Charles G., Camacho, Luis H. +18 more·2012·New England Journal of Medicine
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- Predictors of responses to immune checkpoint blockade in advanced melanomaNicolas Jacquelot, María P. Roberti, David Pierre Enot, Sylvie Rusakiewicz, Nils Ternès, S. Jegou, David Michael Woods, Andressa L. Sodré, Morten Hansen, Yaron Meirow et al. · 2017 · Nature Communications
- Abscopal, immunological effects of radiotherapy: Narrowing the gap between clinical and preclinical experiencesNikko Brix, Anna Tiefenthaller, Heike Anders, Claus Belka, Kirsten Lauber · 2017 · Immunological Reviews
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- <i>TP53</i>
mutations in myelodysplastic syndromes and secondary AML confer an immunosuppressive phenotypeSallman, David A., McLemore, Amy F., Aldrich, Amy L., Komrokji, Rami S., McGraw, Kathy L., Dhawan, Abhishek, Geyer, Susan, Hou, Hsin-An, Eksioglu, Erika A., Sullivan, Amy et al. · 2020 · Blood
- The Society for Immunotherapy of Cancer consensus statement on tumour immunotherapy for the treatment of cutaneous melanomaHoward L. Kaufman, John M. Kirkwood, Frank Stephen Hodi, Sanjiv S. Agarwala, THOMAS T. AMATRUDA, Steven D. Bines, Joseph I. Clark, Brendan D. Curti, Marc S. Ernstoff, Thomas Frank Gajewski et al. · 2013 · Nature Reviews Clinical Oncology
- PD-1 and PD-L1 Expression in Renal Cell Carcinoma with Sarcomatoid DifferentiationRichard Wayne Joseph, Sherri Z. Millis, Estrella M. Carballido, David H. Bryant, Zoran Gatalica, Sandeep K. Reddy, Alan Haruo Bryce, Nicholas J. Vogelzang, Melissa Stanton, Erik P. Castle et al. · 2015 · Cancer Immunology Research
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- The role of imaging in the management of progressive glioblastomaTimothy Charles Ryken, Nafi Aygün, Johnathan Morris, Marin Leigh Schweizer, Rajeshwari Nair, Cassandra Nichole Spracklen, Steven N. Kalkanis, Jeffrey J. Olson · 2014 · Journal of Neuro-Oncology
- A new insight in chimeric antigen receptor-engineered T cells for cancer immunotherapyErhao Zhang, Hanmei Xu · 2017 · Journal of Hematology & Oncology
- Sarcoidosis-Like Reactions Induced by Checkpoint InhibitorsIoannis Gkiozos, Alexandra Kopitopoulou, Alexandros Kalkanis, Ioannis N. Vamvakaris, Marc A. Judson, Konstantinos Nikolaos Syrigos · 2018 · Journal of Thoracic Oncology
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- Reprogramming the immunological microenvironment through radiation and targeting AxlTodd Anthony Aguilera, Marjan Rafat, Laura Castellini, Hussein Shehade, Mihalis S. Kariolis, Angela Bik‐Yu Hui, Henning Stehr, Rie von Eyben, Dadi Jiang, Lesley G. Ellies et al. · 2016 · Nature Communications
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- Molecular and clinical characterization of PD-L1 expression at transcriptional level via 976 samples of brain gliomaZheng Wang, Chuanbao Zhang, Xing Liu, Zhiliang Wang, Lihua Sun, Guanzhang Li, Jingshan Liang, Huimin Hu, Yanwei Liu, Wei Zhang et al. · 2016 · OncoImmunology
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- Exomics and immunogenicsStéphane Champiat, Charles Ferté, Sophie Lebel‐Binay, Alexander M.M. Eggermont, Jean‐Charles Soria · 2014 · OncoImmunology
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- Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph NodesLaura Jeanbart, Marie Christine Ballester, Alexandre de Titta, Patricia Corthésy, Pedro J. Romero, Jeffrey A. Hubbell, Melody A. Swartz · 2014 · Cancer Immunology Research
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- Targeted antibody and cytokine cancer immunotherapies through collagen affinityIshihara, Jun, Ishihara, Ako, Sasaki, Koichi, Lee, Steve Seung-Young, Williford, John-Michael, Yasui, Mariko, Abe, Hiroyuki, Potin, Lambert, Hosseinchi, Peyman, Fukunaga, Kazuto et al. · 2019 · Science Translational Medicine
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- Immune Checkpoint Inhibitors: Making Immunotherapy a Reality for the Treatment of Lung CancerJulie Renee Brahmer, Drew M. Pardoll · 2013 · Cancer Immunology Research
- Impact of the immune system and immunotherapy in colorectal cancer.Janet L. Markman, Stephen Lawrence Shiao · 2015 · PubMed Central
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- New immunotherapies targeting the PD-1 pathwayJordan M. Chinai, Murali Janakiram, Fuxiang Chen, Wantao Chen, Mark Kaplan, Xingxing Zang · 2015 · Trends in Pharmacological Sciences
- The Tumor Microenvironment Regulates Sensitivity of Murine Lung Tumors to PD-1/PD-L1 Antibody BlockadeHoward Y. Li, Maria V. McSharry, Bonnie Bullock, Teresa T. Nguyen, Jeff Kwak, Joanna M. Poczobutt, Trisha R. Sippel, Lynn E. Heasley, Mary C. M. Weiser-Evans, Eric T. Clambey et al. · 2017 · Cancer Immunology Research
- Emerging trends in colorectal cancer: Dysregulated signaling pathways (Review)Rehan Ahmad, Jaikee Kumar Singh, Amoolya Wunnava, Omar Abdullah Al-Obeed, Maha‐Hamadien Abdulla, Sandeep Kumar Srivastava · 2021 · International Journal of Molecular Medicine
- The role of B7 family molecules in hematologic malignancyPaul Greaves, John G. Gribben · 2012 · Blood
- Predictive relevance of PD-L1 expression combined with CD8+ TIL density in stage III non-small cell lung cancer patients receiving concurrent chemoradiotherapyTakaaki Tokito, Koichi Azuma, Akihiko Kawahara, Hidenobu Ishii, Kazuhiko Yamada, Norikazu Matsuo, Takashi Kinoshita, Naohisa Mizukami, Hirofumi Ono, Masayoshi Kage et al. · 2016 · European Journal of Cancer
- Expression of programmed death ligand-1 on tumor cells varies pre and post chemotherapy in non-small cell lung cancerJin Sheng, Wenfeng Fang, Juan Yu, Nan Chen, Jianhua Zhan, Yuxiang Ma, Yunpeng Yang, Yan Huang, Hongyun Zhao, Li Zhang · 2016 · Scientific Reports
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- Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell ResponsesNorman Woller, Engin Gürlevik, Bettina Fleischmann-Mundt, Anja Schumacher, Sarah Knocke, Arnold Kloos, Michael Saborowski, Robert Geffers, Michael Peter Manns, Thomas Christian Wirth et al. · 2015 · Molecular Therapy
- Neurologic complications of immune checkpoint inhibitorsAlexandra M. Haugh, John C. Probasco, Douglas Buckner Johnson · 2020 · Expert Opinion on Drug Safety
- Checkpoint blockade for cancer therapy: revitalizing a suppressed immune systemYago Pico de Coaña, Aniruddha Choudhury, Rolf W. Kiessling · 2015 · Trends in Molecular Medicine
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