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Cited by 438

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

Effects of Off-Pump and On-Pump Coronary-Artery Bypass Grafting at 1 Year

Open access
Lamy, André, Devereaux, P.J., Prabhakaran, Dorairaj, Taggart, David P., Hu, Shengshou, Paolasso, Ernesto, Straka, Zbynek, Piegas, Leopoldo S., Akar, Ahmet Ruchan, Jain, Anil R., Noiseux, Nicolas, Padmanabhan, Chandrasekar, Bahamondes, Juan-Carlos, Novick, Richard J., Vaijyanath, Prashant, Reddy, Sukesh Kumar, Tao, Liang, Olavegogeascoechea, Pablo A., Airan, Balram, Sulling, Toomas-Andres, Whitlock, Richard P., Ou, Yongning, Pogue, Janice, Chrolavicius, Susan, Yusuf, Salim·2013·New England Journal of Medicine
DOI 10.1056/nejmoa1301228
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Abstract

BACKGROUND: Previously, we reported that there was no significant difference at 30 days in the rate of a primary composite outcome of death, myocardial infarction, stroke, or new renal failure requiring dialysis between patients who underwent coronary-artery bypass grafting (CABG) performed with a beating-heart technique (off-pump) and those who underwent CABG performed with cardiopulmonary bypass (on-pump). We now report results on quality of life and cognitive function and on clinical outcomes at 1 year. METHODS: We enrolled 4752 patients with coronary artery disease who were scheduled to undergo CABG and randomly assigned them to undergo the procedure off-pump or on-pump. Patients were enrolled at 79 centers in 19 countries. We assessed quality of life and cognitive function at discharge, at 30 days, and at 1 year and clinical outcomes at 1 year. RESULTS: At 1 year, there was no significant difference in the rate of the primary composite outcome between off-pump and on-pump CABG (12.1% and 13.3%, respectively; hazard ratio with off-pump CABG, 0.91; 95% confidence interval [CI], 0.77 to 1.07; P=0.24). The rate of the primary outcome was also similar in the two groups in the period between 31 days and 1 year (hazard ratio, 0.79; 95% CI, 0.55 to 1.13; P=0.19). The rate of repeat coronary revascularization at 1 year was 1.4% in the off-pump group and 0.8% in the on-pump group (hazard ratio, 1.66; 95% CI, 0.95 to 2.89; P=0.07). There were no significant differences between the two groups at 1 year in measures of quality of life or neurocognitive function. CONCLUSIONS: At 1 year after CABG, there was no significant difference between off-pump and on-pump CABG with respect to the primary composite outcome, the rate of repeat coronary revascularization, quality of life, or neurocognitive function. (Funded by the Canadian Institutes of Health Research; CORONARY ClinicalTrials.gov number, NCT00463294.).

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Metadata

Authors
Lamy, A., Devereaux, P. J., Prabhakaran, D., Taggart, D. P., Hu, S., Paolasso, E., Straka, Z., Piegas, L. S., Akar, A. R., Jain, A. R., Noiseux, N., Padmanabhan, C., Bahamondes, J.-C., Novick, R. J., Vaijyanath, P., Reddy, S. K., Tao, L., Olavegogeascoechea, P. A., Airan, B., Sulling, T.-A., Whitlock, R. P., Ou, Y., Pogue, J., Chrolavicius, S., & Yusuf, S.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
2013-03-28
Volume
368
Issue
13
Pages
1179-1188
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
DOI
10.1056/nejmoa1301228
OpenAlex
W2107706993
Cited by
438
References
25
FWCI
61.67
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Effects of Off-Pump and On-Pump Coronary-Artery Bypass Grafting at 1 Year. https://app.cochat.ai/papers/10.1056/nejmoa1301228
The paper
Lamy, A., Devereaux, P. J., Prabhakaran, D., Taggart, D. P., Hu, S., Paolasso, E., Straka, Z., Piegas, L. S., Akar, A. R., Jain, A. R., Noiseux, N., Padmanabhan, C., Bahamondes, J.-C., Novick, R. J., Vaijyanath, P., Reddy, S. K., Tao, L., Olavegogeascoechea, P. A., Airan, B., . . . Yusuf, S. (2013). Effects of Off-Pump and On-Pump Coronary-Artery Bypass Grafting at 1 Year. New England Journal of Medicine. https://doi.org/10.1056/nejmoa1301228

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.