The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Five-Year Outcomes after Off-Pump or On-Pump Coronary-Artery Bypass Grafting
Open accessAbstract
BACKGROUND: We previously reported that there was no significant difference at 30 days or at 1 year in the rate of the composite outcome of death, stroke, myocardial infarction, or renal failure between patients who underwent coronary-artery bypass grafting (CABG) performed with a beating-heart technique (off-pump) and those who underwent CABG performed with cardiopulmonary bypass (on-pump). We now report the results at 5 years (the end of the trial). METHODS: A total of 4752 patients (from 19 countries) who had coronary artery disease were randomly assigned to undergo off-pump or on-pump CABG. For this report, we analyzed a composite outcome of death, stroke, myocardial infarction, renal failure, or repeat coronary revascularization (either CABG or percutaneous coronary intervention). The mean follow-up period was 4.8 years. RESULTS: There were no significant differences between the off-pump group and the on-pump group in the rate of the composite outcome (23.1% and 23.6%, respectively; hazard ratio with off-pump CABG, 0.98; 95% confidence interval [CI], 0.87 to 1.10; P=0.72) or in the rates of the components of the outcome, including repeat coronary revascularization, which was performed in 2.8% of the patients in the off-pump group and in 2.3% of the patients in the on-pump group (hazard ratio, 1.21; 95% CI, 0.85 to 1.73; P=0.29). The secondary outcome for the overall period of the trial - the mean cost in U.S. dollars per patient - also did not differ significantly between the off-pump group and the on-pump group ($15,107 and $14,992, respectively; between-group difference, $115; 95% CI, -$697 to $927). There were no significant between-group differences in quality-of-life measures. CONCLUSIONS: In our trial, the rate of the composite outcome of death, stroke, myocardial infarction, renal failure, or repeat revascularization at 5 years of follow-up was similar among patients who underwent off-pump CABG and those who underwent on-pump CABG. (Funded by the Canadian Institutes of Health Research; CORONARY ClinicalTrials.gov number, NCT00463294 .).
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Yusuf, S., Zucker, D., Passamani, E., Peduzzi, P., Takaro, T., Fisher, L. D., Kennedy, J. W., Davis, K., Killip, T., Norris, R., et al. (1994) · The Lancet · doi:10.1016/s0140-6736(94)91963-1 · Cited by 2,134
Self-citationStrategies for Multivessel Revascularization in Patients with Diabetes
Farkouh, M. E., Domanski, M., Sleeper, L. A., Siami, F. S., Dangas, G., Mack, M., Yang, M., Cohen, D. J., Rosenberg, Y., Solomon, S. D., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1211585 · Cited by 1,922
Cognitive Trajectories after Postoperative Delirium
Saczynski, J. S., Marcantonio, E. R., Quach, L., Fong, T. G., Gross, A., Inouye, S. K., & Jones, R. N. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1112923 · Cited by 1,188
On-Pump versus Off-Pump Coronary-Artery Bypass Surgery
Shroyer, A. L., Grover, F. L., Hattler, B., Collins, J. F., McDonald, G. O., Kozora, E., Lucke, J. C., Baltz, J. H., & Novitzky, D. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0902905 · Cited by 1,148
Off-Pump or On-Pump Coronary-Artery Bypass Grafting at 30 Days
Lamy, A., Devereaux, P. J., Prabhakaran, D., Taggart, D. P., Hu, S., Paolasso, E., Straka, Z., Piegas, L. S., Akar, A. R., Jain, A. R., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1200388 · Cited by 707
Self-citationPuskas, J. D., Williams, W. H., Mahoney, E. M., Huber, P. R., Block, P. C., Duke, P. G., Staples, J. R., Glas, K. E., Marshall, J. J., Leimbach, M. E., et al. (2004) · JAMA · doi:10.1001/jama.291.15.1841 · Cited by 565
Off-Pump versus On-Pump Coronary-Artery Bypass Grafting in Elderly Patients
Diegeler, A., Börgermann, J., Kappert, U., Breuer, M., Böning, A., Ursulescu, A., Rastan, A., Holzhey, D., Treede, H., Rieß, F.-C., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1211666 · Cited by 519
Effects of Off-Pump and On-Pump Coronary-Artery Bypass Grafting at 1 Year
Lamy, A., Devereaux, P. J., Prabhakaran, D., Taggart, D. P., Hu, S., Paolasso, E., Straka, Z., Piegas, L. S., Akar, A. R., Jain, A. R., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1301228 · Cited by 438
Self-citationNeed for expertise based randomised controlled trials
Devereaux, P. J., Bhandari, M., Clarke, M., Montori, V. M., Cook, D. J., Yusuf, S., Sackett, D. L., Cinà, C. S., Walter, S. D., Haynes, B., et al. (2005) · BMJ · doi:10.1136/bmj.330.7482.88 · Cited by 427
Self-citationA Comparison of On-Pump and Off-Pump Coronary Bypass Surgery in Low-Risk Patients
Nathoe, H. M., van Dijk, D., Jansen, E. W. L., Suyker, W. J. L., Diephuis, J. C., van Boven, W.-J., de la Rivière, A. B., Borst, C., Kalkman, C. J., Grobbee, D. E., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa021775 · Cited by 402
Metadata
- Authors
- Lamy, A., Devereaux, P. J., Prabhakaran, D., Taggart, D. P., Hu, S., Straka, Z., Piegas, L. S., Avezum, A., Akar, A. R., Lanas Zanetti, F., Jain, A. R., Noiseux, N., Padmanabhan, C., Bahamondes, J.-C., Novick, R. J., Tao, L., Olavegogeascoechea, P. A., Airan, B., Sulling, T.-A., Whitlock, R. P., Ou, Y., Gao, P., Pettit, S., & Yusuf, S.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2016-12-15
- Volume
- 375
- Issue
- 24
- Pages
- 2359-2368
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2533292853
- Cited by
- 432
- References
- 20
- FWCI
- 52.77
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Lamy, A., Devereaux, P. J., Prabhakaran, D., Taggart, D. P., Hu, S., Straka, Z., Piegas, L. S., Avezum, A., Akar, A. R., Lanas Zanetti, F., Jain, A. R., Noiseux, N., Padmanabhan, C., Bahamondes, J.-C., Novick, R. J., Tao, L., Olavegogeascoechea, P. A., Airan, B., Sulling, T.-A., . . . Yusuf, S. (2016). Five-Year Outcomes after Off-Pump or On-Pump Coronary-Artery Bypass Grafting. New England Journal of Medicine. https://doi.org/10.1056/nejmoa1601564
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
